natimmunol
Nature Immunology publishes original research, reviews and commentary of the highest quality and significance in all areas of immunology.
- Our February issue is now live! www.nature.com/ni/volumes/2...
- Congratulations to Fred Ramsdell, Mary Brunkow and Shimon Sakaguchi - the 2025 Winners of the Nobel Prize in Physiology or Medicine. #Treg_cells #Foxp3 #Immune_regulation
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- Check out the August issue of Nature Aging featuring a focus on immune aging. See www.nature.com/nataging and rdcu.be/eC58o
- Idoyaga and colleagues suggest that pDCs can lose the ability to secrete IFN-I and acquire the transcriptional, epigenetic and functional features of cDCs. Read it here: rdcu.be/eBB5e www.nature.com/articles/s41...
- Sun and colleagues show that the transcription factor TCF19 drives a transcriptional program that coordinates both innate and adaptive NK cell responses against viral infection. Read it here:https://rdcu.be/eBB3K www.nature.com/articles/s41...
- Klein and colleagues find that cathepsin L shapes CD4+ T cell selection by promoting full repertoire diversity and fine-tuning CD4+ T cell functionality. Read it here: rdcu.be/etDy2 www.nature.com/articles/s41...
- Fang and colleagues find that succinate can suppress Foxp3 expression and enhance colitis severity. Read it here: rdcu.be/etDuE www.nature.com/articles/s41...
- Amarnath and colleagues find that PD-1 controls coinhibitory receptor expression in Tregs. Read it here: rdcu.be/etDtN www.nature.com/articles/s41...
- We Stand Up for Science!!!
- “In an unusual act of public protest, more than 340 scientists and staff at the National Institutes of Health today released a statement charging NIH officials and their superiors with politicizing science.” www.science.org/content/arti... #StandUpForScience #BethesdaDeclaration
- Joulia et al use single cell spatial transcriptomics to profile the lung in health and during asthma and identify discrete proinflammatory spatial niches that produce alarmins and chemokines. Read it here: rdcu.be/epjN7 www.nature.com/articles/s41...
- Mak and colleagues find that double positive thymocytes express α9 nicotinic ACh receptors and these control negative selection. Read it here: rdcu.be/epjNm www.nature.com/articles/s41...
- Penninger and colleagues developed bat respiratory and intestinal organoids and find there are type I and III IFN responses to viruses, including Marburg virus. Read it here: rdcu.be/epjMK www.nature.com/articles/s41...
- Congratulations to all of the trainee awardees at the recent Aegean Conference on Innate Immunity. Well done all!!!
- Chaudhry et al show that the transcriptional repressor GFI1 is required for the generation and maintenance of stem cell memory CD8+ T cells. Read it here: www.nature.com/articles/s41...
- Paul Klenerman and colleagues combine single cell and spatial transcriptomics to provide a resource of the immune environment in adults and children with celiac disease. Read it here: rdcu.be/el8rn www.nature.com/articles/s41...
- Iwasaki and colleagues show that mucosal vaccine boosters can induce protective immune responses without any adjuvant by retooling lymph node resident memory B cells with memory T cells acting as a natural adjuvant. Read it here: rdcu.be/elTur www.nature.com/articles/s41...
- Sanders et al find that T cells in the tumor can take up adenosine via ENT1 and this suppresses their anti-tumor response, ENT1 inhibition combined with anti-PD1 could control tumor growth in models resistant to immune checkpoint blockade. Read it here: rdcu.be/elTq8 www.nature.com/articles/s41...
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- Last Chance to Submit! Late-breaking abstract submissions for #IUIS2025 close May 6! Share your research with the global immunology community and help shape the science of tomorrow. 🔗 Submit here: iuis2025.org/abstracts/ #Immunology #Science2025 #CallForAbstracts #IUIS
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