GlycoCaging, a targeted drug delivery system using plant oligosaccharide glycoconjugates, enables microbiota-activated colonic drug release, reducing off-target effects while maintaining drug efficacy in inflammatory bowel disease
#NBThighlight www.science.org/doi/10.1126/...
Bespoke plant glycoconjugates for gut microbiota-mediated drug targeting
The gut microbiota of mammals possess unique metabolic pathways with untapped therapeutic potential. Using molecular insights into dietary fiber metabolism by the human gut microbiota, we designed a t...
