😱 Tumors sabotaging the immune system! New study in
@natcellbio.nature.com shows that phosphoethanolamine in tumor interstitial fluid disables T cells by depleting diacylglycerol, crippling their signaling. Big find from
@delgoffelab.bsky.social.
🧪
doi.org/10.1038/s415...
Tumour interstitial fluid-enriched phosphoethanolamine suppresses T cell function
Nature Cell Biology - Wang, Wilfahrt and colleagues show that phosphoethanolamine, a phospholipid intermediate, is enriched in tumour interstitial fluid and induces T cell dysfunction, in part by...