Viral immune evasion:
Cytomegalovirus Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity
#virology #immunology
Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity - Nature Communications
The role of viral Fc-gamma receptors in rhesus cytomegalovirus (RhCMV) infection is unclear. Here, the authors characterized RhCMV vFcγRs and report that their deletion did not affect virus replication, tropism or superinfection in rhesus macaques but increased susceptibility of the virus to antibody control.
