Chaudhry et al show that the transcriptional repressor GFI1 is required for the generation and maintenance of stem cell memory CD8+ T cells. Read it here:
www.nature.com/articles/s41...
GFI1-driven transcriptional and epigenetic programs maintain CD8+ T cell stemness and persistence - Nature Immunology
Belz and colleagues show that GFI1, a transcriptional repressor that recruits histone-modifying enzymes, is necessary for the generation and maintenance of stem cell memory CD8+ T cells.
