Patrycja Kozik
Cell biologist and immunologist.
Group Leader at MRC LMB @mrclmb.bsky.social
🧪 Dendritic cells, antigen presentation, endocytic escape
- Reposted by Patrycja KozikAbsolutely delighted that our latest paper is out today @natimmunol.nature.com. It has taken five years to uncover a role for cross-presentation in shaping the immune visibility of tumour antigens. A labour of love led by @drjonlim.bsky.social and Oliver Schulz. Great start of 2026!
- Reposted by Patrycja KozikDay 24 of making proteins for #ArtAdventCalendar The nuclear pore complex is a huge pore made of hundreds of proteins, that allows the flow of nucleic acids and proteins between the nucleus and cytoplasm. It also looks like a wreath! Merry Christmas! More projects: e-nox.net/portfolio/ #SciArt
- Reposted by Patrycja KozikWe are thrilled to share our new pre-print on the molecular anatomy of nuclear proteasome in human sperm cells! #In-cellcryo-ET + #SPA + #LM! @piotrkolata.bsky.social @a-dsantos.bsky.social, @tomdendooven.bsky.social!! doi.org/10.64898/202...
- Reposted by Patrycja KozikOrganelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
- Organelles harbour pH gradients biorxiv.org/content/10.64898/20…
- Reposted by Patrycja KozikMy "News & views" was published today @natmethods.nature.com Thanks @ritastrack.bsky.social for the invitation to write it and Allison Doerr for the editing after Rita left... www.nature.com/articles/s41...
- Reposted by Patrycja KozikI am excited to share that our work, in which we have dissected the signals driven by the nucleoside-modified mRNA and LNP components of mRNA vaccines that regulate germinal center (GC) responses, is now published in Cell! www.cell.com/cell/fulltex...
- Reposted by Patrycja KozikHow does a macrophage decide to eat or simply nibble? Check out our latest paper! You can also read this nice review. Congrats Caitlin for leading this amazing work! www.nature.com/articles/s41... www.nature.com/articles/s41...
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- Reposted by Patrycja KozikI have a PhD position available with start date September 2026 at the University of Manchester. Proteomics analysis of flow cytometry-based isolated pathogen-containing phagosomes Due to funding requirements, this position is for UK home students only. www.findaphd.com/phds/project...
- Reposted by Patrycja KozikHappy to share a new preprint from our lab, uncovering "spooky action at a distance" - for RNA Polymerase II: www.biorxiv.org/content/10.6...
- Reposted by Patrycja Kozik🔬 Call to create junior research groups at the Institut Pasteur Focus: Infectious diseases, host-microbe interactions, vaccines Special interest: AI methodologies 📅 Deadline: Feb 9, 2026 👥 2-12 years post-PhD Apply now 📝 research.pasteur.fr/en/call/crea... #JobOpportunity #Research
- Time for a new pre-print! How do dendritic cells control pore formation in their own endocytic compartments? Our work shows that the unique transmembrane anchor of perforin-2 does not protect DC membranes, but instead it enables antigen escape during cross-presentation doi.org/10.64898/202...
- Reposted by Patrycja KozikThe EMBO Gold Medal 2025 was awarded to Tanmay Bharat and David Bikard: embo.org/press-releases/embo… 🧪 At #CellBio2025, the EMBO Gold Medal was handed over to David Bikard in recognition of his pioneering work on #GeneEditing.
- Reposted by Patrycja KozikSome archaea—an ancient group of microorganisms—have an entirely novel genetic code, according to a new study in Science. The findings expand our understanding of how alternative genetic codes evolve and hint at new molecular tools for biotechnology applications. scim.ag/4omApQ7
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- Reposted by Patrycja KozikBBC News - Top UK scientist says research visa restrictions endanger economy www.bbc.com/news/article...
- Reposted by Patrycja KozikCheck out the latest paper from Leo James and William McEwan which explains the science behind LMB spin out TRIMTECH Therapeutic's TRIMTAC® degraders ⤵️
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- Reposted by Patrycja KozikToday, our animation synthesizing decades of research on actin-mediated endocytosis in budding yeast was published: journals.biologists.com/jcs/article/... The result of a fantastic Iwasa-Drubin lab collaboration. @margotriggi.bsky.social @jiwasa.bsky.social movie.biologists.com/video/10.124...
- Reposted by Patrycja KozikHappy to share our newest preprint on antigen presentation of Mtb-derived peptides on MHC-I: www.biorxiv.org/cgi/content/... This is a follow up to our previous paper where we applied immunopeptidomics to understand MHC-I presentation by Mtb-infected cells: elifesciences.org/articles/84070
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- Reposted by Patrycja KozikAn authoritative review on phagosome immunobiology by David Underhill and Kai Li. Highly recommend for anyone interested in innate immunity, antigen presentation, infection and host defense. @cedarssinai.bsky.social rdcu.be/eNIFY
- Reposted by Patrycja KozikPre-print alert! And this one really is a must read for anyone that does spectral #flowcytometry. It is a complete, fully-automated spectral unmixing pipeline that reduces error up to 9000-fold. Want to get a tough sample, like lung, looking like this? Read more! www.biorxiv.org/content/10.1...
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- Looking forward to meeting PFP enthusiasts at the Prato conference on Pore Forming Proteins in June! ⏰ Early Bird Registration deadline - May 16th ⏰ www.pratopores.org/speakers #PFPsky
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- Reposted by Patrycja KozikWow! Amazing response in the first few days of registration opening for www.emds2025.com Be sure to register early to avoid disappointment. 🚨 Abstract deadline is FRIDAY 30th MAY (Sneak peak of @profandrewmac.bsky.social rehearsing for the 'Scotland Experience' social.)
- 🚨 REGISTRATION NOW OPEN!!! Head to www.emds2025.com to register and submit your abstracts. Full programme is now available. NB: Spaces are limited, so don't delay, register today! @britsocimm.bsky.social @efis-immunology.bsky.social @societymucosalimm.bsky.social @natrevimmunol.nature.com
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- Reposted by Patrycja KozikThe LMB Rising Talent Fellowship for Black heritage scientists is open for applicants! With this 3 year postdoc position we want to enable scientists of Black heritage to learn & grow their experience. To apply and for full details check here: www2.mrc-lmb.cam.ac.uk/recruitment/... Please share!
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- Reposted by Patrycja KozikJoin our Structural Studies Division, leading a research group developing computational methods to address questions in molecular & cellular biology! You will be supported by core funding, excellent facilities & enthusiastic colleagues. Apply by 18 MAR www.nature.com/naturecareer...
- Reposted by Patrycja KozikWe are excited to announce the 2nd Symposium on the Immunobiology of Pattern Recognition Receptors, Oct 1-2 2025, Lausanne, Switzerland. Registrations open March 1 - Attendance limited to 150 participants. More info: wp.unil.ch/immunobiolog... #ImmunoSky
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- Just a little reminder on the important role of perforin-2 in transport... 🎁🎁🎁 🎄 Happy Christmas everyone! 🎄 Image credits: @e-nox.net #KozikLabScience #PFPsky
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- News from the lab: we went skating and we all survived! Thank you to @immunoah.bsky.social for organising a joint Christmas lunch 🎄 #KozikLabMembers #KozikLabUpdates
- It is great to see a lot of familiar faces at #UKMT2024 in London! A big thank you to Chris Stefan and @jezcarlton.bsky.social for organising and putting together an exciting programme for the day. #KozikLabUpdates
- Reposted by Patrycja KozikOk, I made a starter pack for membrane trafficking and organelles (broadly defined). Feel free to self-nominate! go.bsky.app/RbtJjt7at://did:plc:qqgx2dooaid3j2qgu4d5xbxc/app.bsky.graph.starterpack/3laoqqodbfc2j
- Reposted by Patrycja KozikFriends, it's fun to see the #immunology community continue to grow! I created a 4th Starter Pack to help folks find each other. If you're an immunologist and you don't see yourself on the lists, let me know 🧪 go.bsky.app/PY5tCas go.bsky.app/FmERUoD go.bsky.app/6aT6qDS go.bsky.app/QSEPDoj
- Friends, the second #immunology starter pack filled in 3 days! I started a third to help folks new to BlueSky rebuild their network Below are the links If you're an immunologist and I have missed you so far, let me know 🧪 go.bsky.app/PY5tCas go.bsky.app/FmERUoD go.bsky.app/6aT6qDS
- Reposted by Patrycja KozikA starter pack for PhD students and Postdocs in Immunology to connect 🔽 Drop a 🧬 and I'll add you to the list. Let's build the upcoming immuno community! #ImmunoSky 🧪 go.bsky.app/RABVXY4at://did:plc:xwfnlcvkqh7d7qvxj2uq3ocy/app.bsky.graph.starterpack/3lchlvjozes2m
- If you are interested in dendritic cells, macrophages, antigen presentation or pore forming proteins, check out the feeds we are working on: Antigen presentation: bsky.app/profile/patr... APCs: bsky.app/profile/patr... Mammalian pore forming proteins: bsky.app/profile/patr...
- #PapersToRead In silico designed MHC class I:peptide binders can activate CAR T cells - from the Baker lab www.biorxiv.org/content/10.1...
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