Some archaea—an ancient group of microorganisms—have an entirely novel genetic code, according to a new study in Science.
The findings expand our understanding of how alternative genetic codes evolve and hint at new molecular tools for biotechnology applications.
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An archaeal genetic code with all TAG codons as pyrrolysine
Multiple genetic codes developed during the evolution of eukaryotes and bacteria, yet no alternative genetic code is known for archaea. We used proteomics to confirm our prediction that certain archae...