Geanncarlo Lugo
@CNRS #immunologist at @IpbsToulouse specialized in host-pathogen interaction, including #tuberculosis #HIV ; he/him/his; opinions=own
- Our work on how a conserved core network in the SARS-CoV-2 nucleocapsid NTD affects stability, RNA-binding affinity, and selectivity of the domain is now online. www.nature.com/articles/s41...
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- 🩸 New @naturecomms.bsky.social study with #IrsiCaixa collaboration explores therapeutic plasma exchange for #LongCovid, assessing its safety and efficacy in a phase II trial. 🧪 The study provides valuable insights into this complex condition. 👇🏽👇🏽👇🏽 www.nature.com/articles/s41...
- Excited to share our last study. Huge congrats to Sarah Monard, Arnaud Métais, @gclugo.bsky.social, @chrisverollet.bsky.social and all colleagues! We have found a mysterious cell type inside TB lung lesions that seems neuron-like but isn't quite a nerve cell. Let's dive in👇 shorturl.at/x4Sb5
- This new study shows that inhibition of S1pr3 ameliorates bleomycin-induced #PulmonaryFibrosis (PF) by reducing #macrophage M2 polarization via the PI3K/Akt-Stat3 signaling pathway, indicating that S1pr3 may be a potential target for PF treatment. #OpenAccess: www.sciencedirect.com/science/arti...
- Everything Is Tuberculosis comes out THE DAY AFTER TOMORROW. I am so excited and also nervous. I hope you like it. Preorder your signed copy at everythingistb.com
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- @jakstat.bsky.social et al. of the Ardolino Lab show that PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway. rupress.org/jem/article/... 📘 In Tumor #Metabolism 2025: rupress.org/jem/collecti... #KSTumorMetab25
- Miao et al. highlight tRNA m1A modification as a regulatory checkpoint in cholesterol #metabolism in CD8+ T cells, suggesting potential novel strategies for #cancer #immunotherapy. rupress.org/jem/article/... 📘 In Tumor Metabolism 2025: rupress.org/jem/collecti... #KSTumorMetab25
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- First TB Journal Club of 2025 meets *this Thursday* 20th at 4pm UK time 🕓 Liz Corbett & Verena Faehling @lshtm.bsky.social will be discussing shorturl.at/AGD8l Duong &al 2024 meta-analysis of VQUIN & TB-CHAMP RCTs of levofloxacin for #MDRTB contacts. Hope to see you there! #tbsky #tuberculosis
- Our methods paper made it to bioRxiv: doi.org/10.1101/2025... Full #cryoET workflows for #plant tissues. Plus some general tricks and tweaks on serial Lift-Out and cryo-FLM. 🧪🧵1/5 #teamtomo #PlantScience #Physcomitrium #Arabidopsis #cryoEM #CLEM
- Pretty sad. Just got the email that CZI is canceling the second round of Diversity Leadership Awards. Private industry will definitely not fill the hole that NIH and NSF are leaving. 😢💔
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- A recent study by the Institut Pasteur highlights the emergence of a cholera strain resistant to 10 antibiotics, including key treatments azithromycin and ciprofloxacin. This study demonstrates the need to strengthen global surveillance of the cholera agent. 🌍🔬 #cholera #AntibioticResistance
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- Join our Infectious diseases & antimicrobial resistance workshop ! Registration form : www.ipbs.fr/mira-worksho... Programme and details : www.ipbs.fr/mira2025/ #AMR #WAAW #AntimicrobialResistance #PublicHealth #Antibiotics #Tuberculosis #healthcareinnovation
- An ascidian tadpole losing its tail in a few hours. Tiny little sea critter at this stage (around 1mm long). Thanks to the Ascidian BioCell Team
- This is 67 cases--a tiny fraction of TB's global burden, which exceeds 10,000,000 active cases per year. But the longer we allow a curable illness to infect and kill millions, the more TB we'll see in the U.S. Tuberculosis is an airborne disease, and TB anywhere is a threat to humans everywhere.
- Kansas Is Battling the Largest Tuberculosis Outbreak Ever Recorded in the U.S. gizmodo.com/kansas-is-battling-…
- Here is a highly recommended thread that summarizes what has happened in scientific landscape in the US since Trump's inauguration. It makes for dystopian reading ⬇️
- An explainer about how health research funding happens and why this NIH funding cycle shutdown matters: www.msnbc.com/opinion/msnb...
- The NIH diversity supplement pages have all been pulled down. What is a diversity supplement and why should the public care? A diversity supplement is funding to help diversify the research workforce. You may be wondering, “so what?”. Let me explain. www.nigms.nih.gov/Pages/PageNo...
- Reducing #TB burden requires understanding local contexts. Our new preprint emphasizes the importance of considering social contact patterns for interventions like active case finding, infection prevention & control, & cluster trial design #TBsky #IDsky #GlobalHealth www.medrxiv.org/content/10.1...
- Ever wonder what snow in the swamp would look like? This is 5 miles into the Louisiana swamps in the Atchafalaya basin... it's unreal... having lived down there for the first 28 years of my life, we never saw anything like this. Smashed records. Curtesy of Garrett Roberts.
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- Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...
- Adaptive immune regulation of innate immunity ✨ the paradigm has been innate immune regulation of adaptive immunity but the relationship is bidirectional. So much to discover and learn here. www.cell.com/immunity/ful...
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- Hey friends! 🌟 My brilliant colleague @gclugo.bsky.social has just landed on our little blue planet! 🛸 An expert in the immunology of TB and TB/HIV coinfection, and honestly, one of the sweetest humans you’ll ever meet. Give him a follow, you won’t regret it! 😉
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