Olivier Neyrolles
Director of https://www.ipbs.fr Toulouse 🇫🇷🇪🇺
Microbe-host enthusiast tackling TB and beyond | Passionate #SciComm advocate | #MicroSky #TBSky #CNRS | He/Him | Views mine
- So inspiring to see the next generation of researchers in action. Their science gets clearer and more impactful every year. Watching Max Caouaille and Aizat Abdul at #TBVAC was genuinely moving. Great science, great storytelling, huge passion. The future of research is in very good hands. 👏
- Reposted by Olivier NeyrollesThe Barber lab is looking to hire post-docs to work on #tuberculosis #immunology using murine and NHP models. BSL3 experience not required. Check out our lab in the NIH intramural program in Bethesda MD!
- Reposted by Olivier NeyrollesA great meeting ahead for host and pathogen aficionados! Keynote speakers: Florence Niedergang (Cochin) and Raphael Valdivia (Duke)- plenty of opportunities for early career researchers to present their work and a very collegial and supportive network. Belfast here we go! Please repost.
- SAVE THE DATE! The 2026 UK CellularMicrobiologyNetwork meeting will be held 22nd - 23rd of June at @wwiem-qub.bsky.social in Belfast. Researchers from the UK and beyond are invited to share exciting work on the mechanisms of host-pathogen interactions. Follow us to stay tuned! www.ukcellmicro.org
- 🥳 𝐄𝐱𝐜𝐢𝐭𝐞𝐝 𝐭𝐨 𝐬𝐡𝐚𝐫𝐞 𝐨𝐮𝐫 𝐥𝐚𝐭𝐞𝐬𝐭 𝐰𝐨𝐫𝐤 𝐬𝐡𝐨𝐰𝐢𝐧𝐠 𝐡𝐨𝐰 𝐩𝐨𝐥𝐲𝐬𝐢𝐚𝐥𝐲𝐥𝐚𝐭𝐢𝐨𝐧, 𝐚 𝐫𝐚𝐫𝐞 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐦𝐨𝐝𝐢𝐟𝐢𝐜𝐚𝐭𝐢𝐨𝐧, 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐞𝐬 𝐢𝐧𝐟𝐥𝐚𝐦𝐦𝐚𝐭𝐨𝐫𝐲 𝐦𝐨𝐧𝐨𝐜𝐲𝐭𝐞 𝐦𝐨𝐛𝐢𝐥𝐢𝐳𝐚𝐭𝐢𝐨𝐧 𝐟𝐫𝐨𝐦 𝐭𝐡𝐞 𝐛𝐨𝐧𝐞 𝐦𝐚𝐫𝐫𝐨𝐰. ✍️ Aurélien Boyancé, Nelly Gilles, @yoannrombouts.bsky.social & coll. @ipbstoulouse.bsky.social 📖 shorturl.at/IDwza 👇 A short thread...
- Inflammatory monocytes are critical for fighting infections (like tuberculosis) and regulating inflammation. We found that the enzyme ST8SIA4, through polysialylation, controls their egress from the bone marrow via the CCR2 receptor, both at steady state and during 𝑀. 𝑡𝑢𝑏𝑒𝑟𝑐𝑢𝑙𝑜𝑠𝑖𝑠 infection.
- Nothing like a good meal with an even better team. Here’s to a bright, productive 2026! 🤩 @mcaouaille.bsky.social @saurabhchugh09.bsky.social @vogeleerp.bsky.social @yoannrombouts.bsky.social & more!
- Reposted by Olivier NeyrollesTwo pieces of fun news: 1. We've launched a new website for our lab: www.brysonlab.org 2. With some new funding, we are recruiting for new postdocs and graduate students. The projects build upon our previous studies of antigen presentation and phagosome biology and go into new exciting dimensions!
- Reposted by Olivier Neyrolles🚨 We are excited to announce that @virginiestevenin.bsky.social has been awarded a starting grant from the @frm-officiel.bsky.social to establish her research team at IPBS and study the nutrition of pathogenic bacteria inside human host cells. More info: shorturl.at/U6zSa #MicroSky #Salmonella
- A big thank-you to @sheetalgandotra.bsky.social & @vivekrao.bsky.social and everyone at CSIR-IGIB for their warm welcome! 😊 What a wonderful day with incredibly friendly hosts and such brilliant, motivated students! 🇫🇷🇮🇳 Long live Franco-Indian cooperation!
- 🚨 𝐍𝐞𝐰 𝐩𝐫𝐞𝐩𝐫𝐢𝐧𝐭 𝐟𝐫𝐨𝐦 𝐨𝐮𝐫 𝐥𝐚𝐛, 𝐚𝐧𝐝 𝐚 𝐟𝐢𝐫𝐬𝐭 𝐢𝐧 𝐭𝐡𝐞 𝐓𝐁 𝐟𝐢𝐞𝐥𝐝! 🚨 We’re thrilled to share our new study revealing how the chromatin regulator SP140 preserves protective T cell immunity during #tuberculosis infection by restraining harmful type I IFN responses. 📖 𝗥𝗲𝗮𝗱 𝘁𝗵𝗲 𝗽𝗿𝗲𝗽𝗿𝗶𝗻𝘁: shorturl.at/r5jd9
- 🔬 𝗙𝗶𝗿𝘀𝘁-𝗲𝘃𝗲𝗿 𝗶𝗻𝘁𝗿𝗮𝘃𝗶𝘁𝗮𝗹 𝗹𝘂𝗻𝗴 𝗺𝗶𝗰𝗿𝗼𝘀𝗰𝗼𝗽𝘆 𝗶𝗻 𝗧𝗕 allowed us to watch T cells in real time inside infected lesions, an unprecedented view made possible by the work of Emma Lefrançais, Léa Fromont & colleagues. Preprint here: shorturl.at/gm20H
- 𝗜𝗣𝗕𝗦 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵𝗲𝗿𝘀 𝗶𝘀𝗼𝗹𝗮𝘁𝗲𝗱 𝗵𝘂𝗺𝗮𝗻 𝗿𝗲𝗴𝘂𝗹𝗮𝘁𝗼𝗿𝘆 𝗯𝗼𝗻𝗲 𝗺𝗮𝗿𝗿𝗼𝘄 𝗮𝗱𝗶𝗽𝗼𝗰𝘆𝘁𝗲𝘀 𝗳𝗼𝗿 𝘁𝗵𝗲 𝗳𝗶𝗿𝘀𝘁 𝘁𝗶𝗺𝗲! These anucleate fat cells still metabolize lipids and glucose, support blood cell production, and may shape the bone marrow niche and hematopoiesis.🩸 📖 shorturl.at/bunUV #Hematopoiesis #Adipocytes #BoneMarrow
- Reposted by Olivier NeyrollesHey friends. I’m looking for a postdoc interested in studying host-pathogen interactions and immunology of tuberculosis. Send me some good people! We have a great group here! Email me joanne@pitt.edu. Thanks!
- Reposted by Olivier NeyrollesIPBS researchers created LiveLung-TB, a BSL-3 imaging platform that visualizes real-time immune responses in Mtb-infected lungs. They found most CD4 T cells fail to reach infected cells, revealing physical barriers that limit TB immunity—a new window into host-pathogen dynamics! 🔬🫁 #Tuberculosis
- Reposted by Olivier Neyrolles#RésultatScientifique 🔎 | Comment les filaments d'actine s'organisent à l'intérieur des cellules et des tissus vivants 🔬 @institutfresnel.bsky.social 🤝 @univ-amu.fr @centralemed.bsky.social @cnrs.fr 📍 @cnrs-dr12.bsky.social
- Reposted by Olivier NeyrollesWhy would Mycobacterium shed its surface right after entering a host cell? Host phagocytes rapidly strip its outer layer, releasing components that alert neighbors and trigger defense responses Our preprint is out, curious to hear your take! 👀 www.biorxiv.org/content/10.1...
- Reposted by Olivier Neyrolles👇👇Last days to submit your abstract to be considered for a short talk! Deadline 24 November!https://www.keystonesymposia.org/conferences/conference-listing/meeting/travel/c42026
- At #SLAMTB conference with friends and colleagues. Feels good to reconnect! 😉 @lucianabalboa.bsky.social @prados-rosales.bsky.social #Montevideo
- Reposted by Olivier NeyrollesTwo M. tuberculosis RelE toxins don’t cut mRNA, they slice 16S rRNA itself, shutting down translation in a totally unexpected way, new study reveals. A big leap in understanding TB’s survival tricks and new angles for therapies. 📖 shorturl.at/Z8MVX ✍️ @genevauxpierre.bsky.social & coll. #MicroSky
- 👏👏👏 So proud of our co-PI! This well-deserved recognition honors Luciana’s outstanding scientific contributions, her dedication to mentoring, and her support for young women in research. Please join me in congratulating her on this incredible achievement!
- We are thrilled to congratulate @lucianabalboa.bsky.social, co-leader of our IPBS/CNRS-CONICET lab, for receiving a special mention in the L’Oréal-UNESCO “For Women in Science” Award 2025. This honor recognizes her exceptional career & dedication to research in infectious diseases. shorturl.at/Gfo4a
- Reposted by Olivier NeyrollesUn immense merci à nos doctorants, au comité organisateur et à nos orateurs invités @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy, pour la réussite de ce superbe 10e Symposium des étudiants de l’IPBS. Bravo à toutes et à tous ! Cap sur le 11e Symposium !
- Reposted by Olivier NeyrollesA huge thank you to our PhD students, the organizing committee, and our guest speakers @mblokesch.bsky.social, F. Mechta-Grigoriou & E. Crubezy for making the 10th IPBS Student Symposium such a success. Kudos to everyone involved! On to the 11th Symposium! 🎉
- Reposted by Olivier NeyrollesExciting #postdoc opportunity in T. Gensollen's group! How early-life interactions between the immune system and microbiota shape lifelong immune imprinting and disease risk Learn more: shorturl.at/F8hqE Deadline: January 15, 2026 Contact: recruit@ipbs.fr #Immunology #Microbiology #Microbiota #Omics
- Reposted by Olivier NeyrollesExciting #postdoc opportunity in KL Ung's group! Understanding the molecular mechanisms of cell wall remodeling in pathogens Learn more: shorturl.at/gPuFV Deadline: January 15, 2026 Contact: recruit@ipbs.fr #Protein #Biochemistry #StructuralBiology #Biophysics #CryoEM
- Reposted by Olivier NeyrollesInsights from Andrea Cooper: Mtb drives expression of type I IFN–mediated #neutrophil accumulation, which limits interaction btwn CD4 T cells & macrophages. Failure to limit type I IFN very early in the process allows rapid progression of disease rupress.org/jem/article/... #Tuberculosis
- Women's medicine, a 'bikini medicine'… « You do realize we have other organs too, right? » That joke is so true, unfortunately! ✍️ Camille Van Belle
- 👏👏👏 Ophélie Dufrançais, @chrisverollet.bsky.social et leurs collègues ! Un travail soutenu par @frm-officiel.bsky.social et @agencerecherche.bsky.social et réalisé en collaboration avec @lp2mlab.bsky.social et @embl.org, entre autres.
- Des chercheurs de l’IPBS (@chrisverollet.bsky.social et coll.) ont découvert que la protéine moésine régule les ostéoclastes, les cellules qui résorbent l’os. Sans elle, les os s’affaiblissent. Une piste prometteuse contre l’ #ostéoporose. 📘 @jcb.org shorturl.at/OhNSa
- Reposted by Olivier NeyrollesDes chercheurs de l’IPBS (@chrisverollet.bsky.social et coll.) ont découvert que la protéine moésine régule les ostéoclastes, les cellules qui résorbent l’os. Sans elle, les os s’affaiblissent. Une piste prometteuse contre l’ #ostéoporose. 📘 @jcb.org shorturl.at/OhNSa
- Reposted by Olivier NeyrollesToo much cell fusion can break your bones, literally! IPBS researchers @chrisverollet.bsky.social & coll. found that moesin keeps bone-resorbing cells (osteoclasts) in check. Without it, bones weaken, a discovery that could inspire new #osteoporosis treatments. 📘 @jcb.org shorturl.at/N0Esc
- Reposted by Olivier NeyrollesWe are inviting applications for postdoctoral fellows in immunology of TB at the South African Tuberculosis Vaccine Initiative, University of Cape Town. For more information see the attached ad: idm.uct.ac.za/media/739223
- Reposted by Olivier NeyrollesOpen position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here: emploi.cnrs.fr/Offres/Docto...
- This!👇
- Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here: emploi.cnrs.fr/Offres/Docto...
- What a fantastic event! Thanks to @carobarisch.bsky.social, Oliver Jäckle-Tietjen, and the amazing students for the kind invite and great organization. Such a pleasure to join! 🤩 @fzborstel.bsky.social
- Yesterday’s NGMI3 symposium @fzborstel.bsky.social was a real highlight 🎉 Great keynotes, inspiring discussions & a lot of fun! Many thanks to #NDI3, #Nordinfect & Oliver JT who did such a great job👏 @oneyrolles.bsky.social, @maxgg.bsky.social, Susanne Häussler, Silke Meiners & Christian Karsten!
- What an honor and joy to speak at Borsteler Herrenhaus for #NDI3 2025! Thrilled to reconnect with friends & colleagues. Special thanks to the brilliant students and @carobarisch.bsky.social for the kind invite & flawless organization! #Immunology #InfectionBiology #NordInfect Fotos: Kerstin Pukall
- Reposted by Olivier NeyrollesA big thank you to our Scientific Advisory Board for their engagement during out meeting this week. So many thoughtful questions and insightful comments! Hans-Georg Kräusslich, @oneyrolles.bsky.social, @sykhalid.bsky.social, @thamlab.bsky.social, Joost Enninga, Friedrich Förster, Ilaria Ferlenghi
- Welcome to the little blue planet @khadershabaana.bsky.social 😉
- Reposted by Olivier Neyrolles#ResultatScientifique🔎| Un transporteur spécifique du bacille de la tuberculose pourrait être la cible de médicaments ? ✍️ @oneyrolles.bsky.social 🤝 @ipbstoulouse.bsky.social 📕 @pnas.org | buff.ly/XAynagm
- Very happy to have attended the inaugural lecture of the 20th congress of the @sfmicrobiologie.bsky.social by my former PhD supervisor, @alainblanchard.bsky.social. Brilliant and moving 🙏🙏🙏
- Excited to share Wendy Le Mouëllic’s PhD work, now published in @pnas.org! It reveals that M. tuberculosis depends on inorganic sulfate import to survive inside host cells—fueling essential processes such as redox balance and stress resistance. Huge congrats to Wendy & colleagues! shorturl.at/WbFQC
- More details here 👇 www.ipbs.fr/a-weak-point...
- Another memorable #TBVACHORIZON WP1 working group meeting in Basel, Switzerland! Grateful to #TBVI and many thanks to Daniel Pinschewer and colleagues for the warm welcome and inspiring discussions. @unibas.ch @horizoneu.bsky.social
- Reposted by Olivier NeyrollesWe are looking to hire post-docs to work on T cell responses to M. tuberculosis infection using murine and NHP models. If you know T cells and wanna work on the top global infectious killer check us out. BSL3 experience not required. The NIH intramural program in Bethesda MD is an amazing place!
- Reposted by Olivier NeyrollesA 2-year postdoc position in my lab, under the supervision of P-Alex Kaminski, on Z-DNA phages and the benefit given by ZTGC DNA and the replication machinery, with attempt to create a Z based minireplicon research.pasteur.fr/en/job/a-two...
- Reposted by Olivier NeyrollesFrom tuberculosis to rheumatoid arthritis: A glycobiology breakthrough enters the valorization phase 👏 @yoannrombouts.bsky.social Thanks @frm-officiel.bsky.social More info: shorturl.at/i3sQd
- Reposted by Olivier NeyrollesBig news from IPBS! Our researchers are coordinators or partners in 8 cutting-edge projects funded by @agencerecherche.bsky.social From DNA vaccine electroporation to drug-resistant pathogens, bone health, allergy, and proteasomes, IPBS is driving innovation in biomedicine! urls.fr/gt6JZf
- Reposted by Olivier NeyrollesWe have an open engineer position to work on type IX secretion (T9SS), under the supervision of @doan_thierry (collab with HP Fierobe & A. Tolonen). 1-year contract, renewable up to 3.5 years. Please apply here or forward to anyone potentially interested: emploi.cnrs.fr/Offres/CDD/U...
- Reposted by Olivier NeyrollesCongratulations to all the newly elected @embo.org members. A special shout-out to our SAB member, Wolf-Dietrich Hardt, on this well-deserved recognition! Outstanding life scientists elected to the EMBO Membership – Press releases – www.embo.org/press-releas...
- Reposted by Olivier Neyrolles🎉🎉🎉 Big congrats to Kien Lam UNG, recipient of the 2025 #ATIP-Avenir award! From decoding antibiotic resistance in M. abscessus to revealing plant hormone transporters in Nature, he is now launching a bold project on how sugar tweaks shape host–pathogen battles. Sweet science! 👏👏👏 shorturl.at/TJiHg
- Honored to award the title of Dr. honoris causa of the University of Toulouse to Dr. Manjula Reddy (CCMB, Hyderabad). A world-renowned microbiologist, Dr. Reddy has made major contributions to our understanding of bacterial cell division. 🇫🇷🇮🇳
- Thrilled to have co-authored this review with amazing colleagues! We dive into the mysteries of T cell immunity in TB and explore how cutting-edge tech could unlock better vaccines. #Tuberculosis #Immunology #TCells #Vaccines @natrevimmunol.nature.com www.nature.com/articles/s41...
- Reposted by Olivier NeyrollesAfter a PhD and two postdocs, I’m very proud to be joining the CNRS as a Chargé de recherche, this is a meaningful milestone. Huge thanks to Claude Bruand, @michaelglickman.bsky.social, and @oneyrolles.bsky.social for their guidance and support. Olivier, let’s turn this into exciting discoveries!
- Reposted by Olivier Neyrolles🏳️🌈 For the 3rd year in a row, IPBS proudly kicks off #PrideMonth by reaffirming our year-round commitment to inclusion, equity & respect. Diversity drives science, and we celebrate every identity that makes our institute stronger. 💪 #LGBTQIA #InclusionMatters #PrideAtIPBS shorturl.at/eyTei
- Hi friends! @goletti-delia.bsky.social just landed on the blue planet! Follow her if you’re interested in TB and other infectious diseases.
- Thrilled to host our Indian colleagues for the first MIRA workshop, the @cnrsbiologie.bsky.social International Research Network on #AMR that I co-coordinate with the amazing Amit Singh! 🇮🇳🇫🇷 Huge thanks to @isabellesaves.bsky.social and team for the stellar organization! #MicroSky
- Reposted by Olivier NeyrollesIn @cp-cellrepmed.bsky.social, IPBS researchers propose a treatment based on optimized antibodies that, in mice, increases the proportion of HEV blood vessels and facilitates killer cell entry into tumors. These molecules are currently in clinical trials ⤵️ buff.ly/Ip3US2l
- Dans @cp-cellrepmed.bsky.social, des chercheurs proposent un traitement à base d’anticorps optimisés qui, chez la souris, augmente la proportion des vaisseaux sanguins HEV et facilite l’entrée des cellules tueuses dans les tumeurs. Ces molécules sont en essai clinique ⤵️ buff.ly/w2dk30U
- Reposted by Olivier NeyrollesDans @cp-cellrepmed.bsky.social, des chercheurs proposent un traitement à base d’anticorps optimisés qui, chez la souris, augmente la proportion des vaisseaux sanguins HEV et facilite l’entrée des cellules tueuses dans les tumeurs. Ces molécules sont en essai clinique ⤵️ buff.ly/w2dk30U
- Reposted by Olivier Neyrolles🤝 @ipbstoulouse.bsky.social 👉 Lire l'article dans Cell Reports Medicine buff.ly/Ip3US2l
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- @ghafrance.bsky.social 80 chercheurs s'engagent pour faire de la recherche contre la tuberculose une priorité européenne ! www.actionsantemondiale.fr/app/uploads/...
- Kicking off the #MIRA workshop in style with a fantastic keynote from Marie-Cécile Ploy on the global state of #AMR research, insightful and inspiring! @ipbstoulouse.bsky.social @cbitoulouse.bsky.social
- Reposted by Olivier Neyrolles🚨My new team at @ipbstoulouse.bsky.social in France currently have an open, fully-funded PhD position 🧑🔬👩🔬to study membrane proteins & transporters of therapeutic interest using cryo-EM & biophysics.🧊🔬🦠 #StructuralBiology #MicroSky Please share 🤝 For more details 👇
- New study reveals how M. tuberculosis PdtaS, a constitutively active kinase, senses both copper and nitric oxide by inhibiting dimerization, not binding. A fresh twist on two-component signaling! ✍️ @michaelglickman.bsky.social and coll. 👏👏👏 📖 shorturl.at/DiWXp #Tuberculosis #MicroSky
- Reposted by Olivier NeyrollesI will be recruiting new postdocs with start dates end 2025 - early 2026. If you'd like to work at the Pasteur Institute in the heart of Paris surrounded by amazing scientists, reach out to discuss possible projects on SynBio / Bacterial Immunity!
- Reposted by Olivier Neyrolles🚨 PhD opportunity in Toulouse! Join a dynamic team to study membrane proteins & transporters of therapeutic interest using cryo-EM, enzymology & biophysics. 📅 Deadline: June 19, 2025 🔗 Funded by @frm-officiel.bsky.social #StructuralBiology #MicroSky More details 👇 shorturl.at/OaVMI
- Reposted by Olivier NeyrollesThis is what can be achieved today due to longstanding federal support of academic basic science alongside close partnership of universities, private industry and NIH intramural initiatives. An ecosystem worth not just saving but doubling down on! innovativegenomics.org/news/first-p...
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- How does TB make you cough? New research from @michaelshiloh.bsky.social & coll. shows hypertransmissible M. tuberculosis strains use phenolic glycolipid to activate sensory neurons via ATP–P2X3 signaling, triggering cough & boosting spread! #Tuberculosis #Neuroscience #Microsky shorturl.at/yfeKM
- Happy to share Saurabh's latest review on the bacterial exometabolome and its role in virulence and pathogenesis, just out in @cp-trendsmicrobiol.bsky.social — and it’s open access! 😉 👏 @saurabhchugh09.bsky.social www.cell.com/trends/micro...
- #Tuberculosis bacteria are evolving how they express, not just what they code. New study reveals Mtb evolves via regulatory mutations, altering virulence gene expression to enhance transmission and drug resistance, highlighting adaptive shifts beyond coding sequence variation. #MicroSky #Evolution
- Reposted by Olivier NeyrollesJoin the Blokesch lab (@EPFL) as a postdoc in Molecular Microbiology 🤩 Study Vibrio cholerae defense systems (phage/plasmid) in a dynamic, collaborative environment in Lausanne close to Lake Geneva in 🇨🇭! Please visit my lab's webpage for details about the position and how to formally apply.
- Reposted by Olivier NeyrollesOur set of new prokaryote-optimized fluorescent proteins is now published ! #microbiology #microsky #microscopy 🧫🦠🔬 www.science.org/doi/10.1126/...
- Reposted by Olivier NeyrollesJoin the 2025 #MIRA workshop, online or in Toulouse! From emerging pathogens to global health solutions, connect with top 🇮🇳🇫🇷 researchers, explore funding, and spark new collaborations. Keynotes by Nagasuma Chandra & Marie-Cécile Ploy! Details & registration: shorturl.at/VMfwn #GlobalHealth #MicroSky
- Reposted by Olivier NeyrollesNew postdoc position in our lab (2 y+): evolutionary genomics of integrons and MGEs with focus on vibrio-phage interactions. Great environment @pasteur.fr for science, career building. Super collaborators @celineloot.bsky.social @amazeld.bsky.social @fredoleroux.bsky.social 3 weeks to apply!
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