Rebecca Berrens
Group leader of transposon group in Oxford at IDRM. #new_pi sites.google.com/view/berrenslab
- Reposted by Rebecca BerrensSad to hear that Oxford Nanopore wants to discontinue the P2Solo later this year in favor of the P2i (the very pricey P2Solo that comes with a GPU to do the basecalling in it) It feels like such a big step in the wrong direction. They are a great sequencing company, not a great GPU upseller...
- Reposted by Rebecca BerrensThe speed at which Oxford Nanopore is cancelling support for their devices is just mind boggling 😳 P2 solo will be decommissioned soon!!! This is not sustainable! @nanoporetech.com
- Reposted by Rebecca Berrens🍄Transposon traffic in the mycocosmos🍄 Fascinating work reveals extensive horizontal TE transfer across fungi (@jromeijn.bsky.social, Iñigo Bañales & @mfseidl.bsky.social; doi.org/10.1016/j.cu...). I wrote a Dispatch to prime non-specialists,check it out here: doi.org/10.1016/j.cu.... #TEworldwide
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- Really excited to share our recent work here today and connect all of you :)
- International Genome Dynamics course in Institut Curie-Paris (April 8-15), experimental and computational methods in multiomics,with a #TE centered session. Free registration, until Jan 15th Don’t miss it! 👉https://training.institut-curie.org/courses/Genome-Dynamics-2026 @institutcurie.bsky.social
- What a cool story. Particularly like the fact of expansion and different TF bdg sites! Really speaks for each locus being differential key regulated.
- New Year, New Paper!🎊 Pervasive cis-regulatory co-option of a transposable element family reinforces cell identity across the mouse immune system www.biorxiv.org/content/10.6... Centerpiece of Jason Chobirko's PhD, talented PhD student co-mentored by Andrew Grimson & me. Really excited about it!🧵
- Reposted by Rebecca Berrens☕Earl Grey v7.0.0 brewed fresh☕ Nested TEs finally get the treatment they deserve: iterative detection of deep nesting, cleaner GFF annotations, and coverage stats that don’t double-count genomic space + a RepeatCraft edge-case fix. Happy new year to the TE folks! 🧬 github.com/TobyBaril/Ea...
- #TEsky still have to read the paper but sounds very interesting.
- Now online in Cancer Discovery @aacrjournals.bsky.social: LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture - by Michael Lee, Yuannyu Zhang, Jian Xu, and colleagues doi.org/10.1158/2159... @stjuderesearch.bsky.social
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- Reposted by Rebecca Berrens🪱 Selfish genes are everywhere and drive some of biology’s biggest innovations (CRISPR, antibody recombination, epigenetics). Yet almost no one asks the obvious question: how does a selfish gene begin? Our new manuscript uncovers how selfishness can emerge directly from the host genome.
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- Reposted by Rebecca BerrensISCO (Innovations in Single-Cell OMICS) will be back in beautiful Barcelona! 🗓️ 28th/29th of May 2026 📍Barcelona Biomedical Research Park @prbb.org (beachfront!) Keynotes: @bartdeplancke.bsky.social and @bocklab.bsky.social Submit your abstract and present your research! www.isco-conference.eu
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- Reposted by Rebecca Berrens🚨Our story is published! Same bones but + dissection of MERVL’s role integrating signals from #ZGA factors, & + about pathological DUX4 activation of NOXA #TEsky. Thanks to all revs for their helpful comments improving the ms. Even #rev3 - until they ghosted us 😜 www.science.org/doi/epdf/10....
- Happy to share our first #bluetorial & our latest #preprint, lead by postdoc @paulchammas.bsky.social. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state: #TEsky #MERVL www.biorxiv.org/content/10.1... (1/8)
- Reposted by Rebecca BerrensIntrigued by a long-standing conundrum in small RNA biology—how nuclear Argonaute proteins silence transposons when they *need* target transcription for their own recruitment—we studied the piRNA pathway. And found a hidden RNA-decay axis from Piwi to the RNA exosome.
- RNA decay via the nuclear exosome is essential for piwi-mediated transposon silencing biorxiv.org/content/10.64898/20…
- Very excited to share our work on locus level transposable elements in development with the @fnucleosome.bsky.social community!
- 🧬🎉Join us on Dec 17th for our last session of 2025! 🎉🧬Two fantastic talks on transcriptional regulation: 🔬JB Lalanne on developmental enhancers (and starting a lab in 2025?) 🔬 @rberrens.bsky.social on transposable elements in development 📋Register here: us06web.zoom.us/webinar/regi...
- Very excited to take part in ISCO in Barcelona next year. Looking forward to great discussions and new ideas!
- ISCO (Innovations in Single-Cell OMICS) will be back in beautiful Barcelona! 🗓️ 28th/29th of May 2026 📍Barcelona Biomedical Research Park @prbb.org (beachfront!) Keynotes: @bartdeplancke.bsky.social and @bocklab.bsky.social Submit your abstract and present your research! www.isco-conference.eu
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- Reposted by Rebecca BerrensTEs aren’t just genomic parasites, they’re also engines of genomic novelty. Our new study with ~2,000 Z. tritici genomes shows repeated TE mobilization waves during global expansion. With @danielcroll.bsky.social & @guidopuccetti.bsky.social 🧬 www.nature.com/articles/s41... #TEworldwide
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- Reposted by Rebecca Berrens#TEsky A comparative analysis of transposable element diversity and evolution across 75 bee genomes doi.org/10.1186/s128...
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- Reposted by Rebecca Berrens1/ Ever needed to annotate TEs in a fungal genome, but didn't know where to start? We have released #MycoMobilome, a community-focused non-redundant database of transposable element consensus sequences for the fungal kingdom, constructed from >4,000 fungal genomes! www.biorxiv.org/content/10.1...
- Reposted by Rebecca BerrensLab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
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- Reposted by Rebecca BerrensOur latest paper on a histone methyltransferase-independent function of PRC2 controlling small RNA dynamics during programmed DNA elimination in Paramecium is now published in #NAR. #RNAbiology #TEsky #smallRNAs #PRC2 #DNAelimination 1/5 academic.oup.com/nar/article-...
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- Reposted by Rebecca Berrens👀Next Wednesday, Oct 22nd, at #FragileNucleosome seminar, we are excited to host @alicelaigle.bsky.social and @seungsookim.bsky.social to tell us about amazing work they are doing! 🗓️Register here for upcoming session and the entire series: us06web.zoom.us/webinar/regi...
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- Reposted by Rebecca Berrens"(...) an extremely large transposon, Teratorn, containing a herpesvirus genome, was inserted into the hoxc12a 3' UTR. This insertion decreased hoxc12a expression & (...) also affected neighboring hox genes, resulting in variations in fin size and the presence or absence of dorsal fins."
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- Reposted by Rebecca BerrensWe are very pleased to announce our joint meeting with the German @gfeev.bsky.social and the Dutch Developmental Biology Societies, which will take place in Potsdam from the 10-13th of March 2026. Registration is now open! www.uni-potsdam.de/en/gfe-meeti...
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- Reposted by Rebecca BerrensThe Peters lab is looking for a new team member! The role transposons play in evolution, basic mechanisms regulating transposition, and applying transposons as tools for genome modification with a special focus on guide RNA-directed transposition. cornell.wd1.myworkdayjobs.com/CornellCaree...
- Reposted by Rebecca BerrensToday I am so pleased to present our work on how chromatin remodelers affect mesoscale chromatin organization. www.science.org/doi/10.1126/...
- Reposted by Rebecca BerrensSee this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
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- nice review on how TEs rise from graveyards! right in time for Halloween.
- Reposted by Rebecca BerrensSo happy to see my first first-author paper published! 🎈 A short thread on how Ectocarpus and its TE secrets have kept me busy lately: rdcu.be/eITQH
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- Reposted by Rebecca BerrensDual transposon sequencing profiles the genetic interaction landscape in bacteria | Science www.science.org/doi/10.1126/...
- Reposted by Rebecca BerrensDelighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols. Thread 1/n
- Reposted by Rebecca Berrens✨Exciting news: the main story of my PhD is out in Science! Together with Christine Moene @cmoene.bsky.social, we explored what happens when you scramble the genome—revealing how Sox2’s position shapes enhancer activation. 📖 Read the full story here: www.science.org/doi/10.1126/...
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