Lis Lowe
Scientist, mum, wife. Fan of gut bacteria, mycobacteria, glycans and cazymes. Mannose evangelist. Lowe Lab, NUBI, Newcastle University
- Reposted by Lis LoweA gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends. www.jbc.org/article/S002...
- Reposted by Lis Lowe#Microbiology The anti-tuberculosis drug bedaquiline targets the mycobacterial ATP synthase, but how that leads to bacterial death is unclear Here the authors clarify how bedaquiline works @jnblab.bsky.social @morwan.me #TBSky #antibiotics #AMR dlvr.it/TQjZ0W
- Reposted by Lis LoweI know what they're getting at with the "could put jobs at risk" but can we focus on the immediate impact? Each suspended round at MRC and BBSRC means about 80 fewer postdoc jobs and the retrospective cuts at MRC add another 30 or so
- Reposted by Lis LoweWith much love RIP Catherine O'Hara.
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- Reposted by Lis LoweI am completely baffled by the total lack of any action or any evidence of speaking out from our scientific ‘leaders’. We’re in a void of information and the consequences are potentially catastrophic- especially as it looks like BBSRC are following suit.
- Reposted by Lis Lowewww.findaphd.com/phds/project... interested in bacterial antagonism? PhD opportunity in our team, see below. Please repost!
- Reposted by Lis LoweHappy New Year – new role! 🎉 We’re looking for a PostDoc to join us in @halllab.bsky.social @unibirmingham.bsky.social. Full-time, fixed-term to March 2028. Note tight closing date: 11 Jan 2026. CV + cover letter (submit via portal). Further details 👇 edzz.fa.em3.oraclecloud.com/hcmUI/Candid...
- Reposted by Lis LoweWe’re excited to share our latest study that reshapes our understanding of Mycobacterium tuberculosis (Mtb) lipid composition, with major implications for drug discovery, immunity, and vaccine development. www.nature.com/articles/s41... A thread.
- Reposted by Lis LoweFantastic to have Prof Matthias Wilmanns from EMBL Hamburg hosted by @kshbeckham.bsky.social to give a @mhd-newcastle.bsky.social seminar on mycobacterial infection #dreamtheme
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- Reposted by Lis LoweAre you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
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- Reposted by Lis LowePleased to see this collaboration with a great PhD student Pei Cing Ng, from Prof. Luning Liu's lab at Liverpool University published. Structure of the H. neapolitanus carbonic anhydrase and localisation in a mini-carboxysome: www.pnas.org/doi/epdf/10....
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- Reposted by Lis LoweExcited to share our preprint led by Carlos Voogdt et al We developed new genetic tools & genome-wide libraries for species of the Bacteroidales order; constructed saturated barcoded transposon libraries in key representatives of three genera. www.biorxiv.org/content/10.1...
- Spending some time collecting memories of Harry today 🥺 - this is when he was elected a Fellow of the Royal Society. If anyone in the #glycotime universe has pictures or memories of Harry Gilbert they want to share please send them my way 💚
- Reposted by Lis LoweNext up, Dr Kate Beckham @kshbeckham.bsky.social The Beckham lab is interested mycobacterial membrane transport processes. They focusing on understanding the steps occurring at the mycobacterial outer membrane. www.ncl.ac.uk/cbcb/staff/p...
- Reposted by Lis LoweDay 2 of MHD introductions 😃 Dr Lis Lowe @lislowe.bsky.social The Lowe lab is focussed on microbial glycobiology. They work on bacterial Cazymes from commensals and pathogens, and are particularly interested in enzymes that target microbial glycans such as the cell walls of Mycobacteria.
- Reposted by Lis LoweAbsolutely delighted to share the labs latest work. We identify and characterise two pathways for D-ribulose utilisation in pathogenic EHEC and Citrobacter.
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- On the way home from a really great CAZyme GRC. Lots of v interesting talks, a poster prize for Jean-Lou, karaoke, lake swims, beers, catching up with friends, and a lot of responsibility in 2029 when I co-Chair the meeting!
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- Reposted by Lis LoweFolddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬 📄 www.biorxiv.org/content/10.1... 🌐 search.foldseek.com/folddisco
- Reposted by Lis LoweLearning from bacterial predators on porin-like proteins that trap lipids at rdcu.be/euXWk! Amazing insights by Rebecca J. Parr & Andrew L. Lovering @unibirmingham.bsky.social, and @lalouxlab.bsky.social, as well as all collaborators including Liz Sockett. #MicroSky #predatoryBacteria #porins
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- Reposted by Lis Lowe🦠 NEW VIDEO 🦠 The molecular biology of how Mycobacterium Tuberculosis evades the immune system so well. Starting with this simulation of a full outer envelope of m.TB--let's explore how the deadliest & most persistent human pathogen completely hacks our immune response. #molecularbiology
- Reposted by Lis LoweIn about a week we (Biological Sciences @ Monash Uni in Melbourne, Australia) will be opening a search for 3 (!!!) permanent academic positions (40% research, 40% teaching, 20% service) at Lecturer/Senior Lecturer. 1 Genomics, 2 Ecology. Please share, email me, DM, follow, send carrier pigeons…
- Reposted by Lis LoweJinich et al. present an important new resource for the Mtb community! The Mycobacterium tuberculosis Transposon Sequencing Database (MtbTnDB) is an interactive web resource summarizing 150+ published screens. #MicroSky #Mycobacterium #tuberculosis onlinelibrary.wiley.com/doi/10.1111/...
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- Reposted by Lis LoweToo cool to be true? 😎 Nope! GlycoShape ReGlyco runs on PyMol through the GlycoMe interface 🥰😍 check out this fab #glycotime tool from Hiren @glyco.me and Ojas @ojas-singh.bsky.social ⤵️🥳🥳🥳🎉🎉
- Holy forking shirtballs this Giro has been 🔥🔥🔥
- Reposted by Lis Lowe“The visa fees are so exceedingly high that it makes coming here very difficult for some people. We are fishing for the best scientists in the world. They want to come and work here because we are such an effective country at science, but if we have these high costs, they can and will go elsewhere.”
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- Reposted by Lis LowePostdoc position available! This is a 2-year post funded by the Academy of Medical Sciences. You'll be based in the Centre for Bacterial Cell Biology here in Newcastle, using super-resolution microscopy to look at the bacterial cell wall. 🔬🦠 Please re-post 🙏 www.jobs.ac.uk/job/DMY885/r...
- Resisting the urge to ask the guy next to me at the bus stop with a phone in one hand and an iPod in the other what he’s listening to.
- Reposted by Lis LoweTwo ERC-funded postdoc positions available in the team - one here and second to follow - please repost! jobs.ncl.ac.uk/job/Newcastl...
- Reposted by Lis LoweThis has been a long journey, but it's now out in final form. @kjamali.bsky.social academic.oup.com/bioinformati...
- Pretty sure my protein is actually Hestu from Legend of Zelda
- Gutted that I can’t get to San Diego for my talk at ACS Mycobacterial cell wall session thanks to the Heathrow closure😭 I can justify buying myself a month of Discovery+ so I can watch cycling all day tomorrow instead to deal with the disappointment right? Right?!
- Reposted by Lis LoweLooking for a PhD opportunity in Microbiology? Consider joining one of the strongest clusters of microbiology research in UK at @newcastleuni.bsky.social, Biosciences Institute, and @cbcb-newcastle.bsky.social. See thread for BBSRC DTP PhD studentships currently advertised.
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- PhD available with me & Paul James looking for exciting new enzymes - www.findaphd.com/phds/project...
- Reposted by Lis LoweExcited to share that our paper on locus visualisation tool LoVis4u is out! Entirely driven by fantastic PhD student Artyom Egorov @egorov.bsky.social academic.oup.com/nargab/artic...
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- Reposted by Lis LoweStarting my Bluesky adventure by highlighting a new paper from the lab!
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- Reposted by Lis Lowe☎️ Calling #MEvoSky ☎️ 2x 5-year research associate / research assistant positions in experimental evolution ERC-funded project: How do mobile genetic elements and defence systems shape bacterial genome evolution? Join the friendly and exciting @mermanchester.bsky.social community in Manchester!
- 🚨 Job alert 🚨 — are you interested in understanding how mobile genetic elements and defence systems shape bacterial genome evolution? 🧬 🧪 🧫 🦠 2x 5-year research positions available in experimental evolution @mermanchester.bsky.social Join us! #microsky www.jobs.manchester.ac.uk/Job/JobDetai...
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- Discovery+ putting the prices up to £30 a MONTH to be able to watch cycling wtaf. Who pays that amount?!?
- Reposted by Lis LoweWe are very pleased to share our latest preprint on the architecture of the membrane complex of the type 7 secretion system involved in bacterial competition in B. subtilis. #CryoEM #microsky
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