Stefan Oehlers
Principal Investigator, Bacterial Pathogenesis Lab (A*STAR ID Labs, Singapore)
@astar-idlabs.bsky.social
Zebrafish models of infection and immunity
www.oehlerslab.org
- Reposted by Stefan OehlersOur EMBO workshop is now live. Visit us in Bath this summer for a two week workshop designed to help you study host-microbe interactions in the zebrafish, and develop the bioinformatics skills needed to analyse the complex data sets that arise from microbiomic studies.
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- Reposted by Stefan OehlersLactic acid lover? Check out @ronni.bsky.social 's new work in @cp-cellhostmicrobe.bsky.social showing how Enterococcus faecalis-derived LA suppresses macrophage activation, in turn promoting bacterial persistence and polymicrobial wound infection in vivo. www.sciencedirect.com/science/arti...
- Tonight/tomorrow morning! Using the zebrafish to explore host genetic susceptibility and live image our model of post TB Mycobacterium abscessus Preview some of the videos bsky.app/profile/oehl...
- Reposted by Stefan OehlersExcited to share work led by the wonderful Gopi Viswanathan examining roles of granuloma neutrophils &defining bacterial transcriptional profiles within mycobacterial granulomas. Cool collab with Qingyun Liu at UNC for evolutionary analysis of granuloma-specific genes www.science.org/doi/10.1126/...
- Reposted by Stefan OehlersWe’re delighted to see this out today! Latest work from the lab reveals insights into the evolution of brain immunity and the developmental and evolutionary plasticity of lymphatic endothelial cells. www.nature.com/articles/s41...
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- Reposted by Stefan OehlersA*STAR/KCL PhD scholarship available! Dream of doing cutting-edge research, travelling between continents, and becoming obsessed with modelling infections in zebrafish? My lab and @oehlerslab.org are looking for you! Project details: 👉 shorturl.at/mkt1a Catalogue page 6, project 2.1!
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- Reposted by Stefan OehlersOver the past weeks I have been reading the earliest papers on zebrafish development, and came to realize that in the “canonized" version of zebrafish history we neglect some important people pre-Streisinger. I will try to correct here the record. Let’s start with Edward C. Roosen-Runge. (1/7)
- My citations are at an all time high. What a science Christmas present from Google scholar
- Reposted by Stefan Oehlers🧵Enterococcus faecalis is not just an extracellular organism. 🧵 A growing body of work shows it can survive + REPLICATE inside host cells, and that intracellular life may seed persistence, dissemination, and reinfection. 1/n #MMBR @asm.org journals.asm.org/doi/10.1128/...
- Reposted by Stefan OehlersWe're looking for a Research Assistant / Senior Research Assistant to join our team. If you're interested in studying the extracellular matrix and tumour microenvironment in cancer, then get in touch. Applications will be reviewed on a rolling basis. garvan.wd3.myworkdayjobs.com/garvan_insti...
- Reposted by Stefan OehlersHey friends. I’m looking for a postdoc interested in studying host-pathogen interactions and immunology of tuberculosis. Send me some good people! We have a great group here! Email me joanne@pitt.edu. Thanks!
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- Published version up at @natcomms.nature.com New data with Aspergillus getting into tuberculous granulomas and growing like it's a member of the extended Myco family doi.org/10.1038/s414...
- Why are prior and concurrent #TB such huge risk factors for M. abscessus infection? #zebrafish preprint lead by our research officer Denise Wee discovers tuberculous granulomas (yellow blob) act as a safe haven for opportunistic mycobacterial pathogens (magenta blobs).
- Reposted by Stefan OehlersKnow the difference.
- Reposted by Stefan Oehlers👇👇Last days to submit your abstract to be considered for a short talk! Deadline 24 November!https://www.keystonesymposia.org/conferences/conference-listing/meeting/travel/c42026
- This explains the recent outbreak of arts and crafts in @astar-idlabs.bsky.social @vignuzzilab.bsky.social @alnajifg.bsky.social
- If you'd like to celebrate the biology of viruses - or the fight against viral diseases - this winter, try out our free and updated #VirusSnowflake designs. Please share, and if you have any photos of Virus Snowflakes in your area it would be lovely to see them! cvr-engagement.co.uk/virus-snowfl...
- Moxi. Warning: "potentially irreversible" side effects from working in my lab
- It’s World AMR Awareness Week, and this year I had the honor to re-imagine and doodle the antibiotics in the antibiotic personality quiz 😇🖍️ Thank u @brxad.bsky.social for this amazing and fun opportunity! C’mon, take the quiz, it’s a #WAAW tradition 😉💊 #IDSky quiz.tryinteract.com#/59e68e3a8ec...
- Work from the most mysterious scientist in @astar-idlabs.bsky.social on his cuckoo flu virus. This is what happens when he was told to stop at 50 passages but kept going out of spite.
- First big piece of research from our SG lab: Fadi's work with Chris Brooke's lab. Flu serially passaged 80X selects a defective genome with improved competition, but is nonviable as a full virus! Notable improvement & safety for DVGs as antiviral RNA therapies! www.biorxiv.org/content/10.1...
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- Reposted by Stefan OehlersWell, this is a brilliant #IDSky article that cuts close to the bone! 😬 Reframes #academia as an infection for which the causative organism may be less easy to define, but that can be just as insidious on affected individuals (clinical academics)! #AcademicSky #MedSky 🧪 @cidjournal.bsky.social
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- Bringing us one step closer to the #zebrafish we were promised by generative AI cartoons elifesciences.org/articles/106...
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- Reposted by Stefan OehlersEnhanced virulence and stress tolerance are signatures of epidemiologically successful Shigella sonnei @sydneylmiles.bsky.social @katholt.bsky.social 🙏to transformative collaborative effort www.nature.com/articles/s41...
- Reposted by Stefan OehlersOur new paper on valve disease in aged #zebrafish is out! onlinelibrary.wiley.com/doi/10.1111/... This has been a long running collaborative effort with contributions from lots of great people!
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- Reposted by Stefan OehlersInterested in establishing your own research group? Our support package for new Group Leaders includes: 🥼2 #Postdocs, a technician & 2 PhD students + lab costs 🔬Full access to core facilities 🧪Access to the MCRC #Biobank ✔️Mentorship, #grant advice & more www.cruk.manchester.ac.uk/career/new-g...
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- Reposted by Stefan OehlersI am biased 😉, but this is an amazing PI and an amazing person, check out this opportunity #immunosky #TB
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- Reposted by Stefan OehlersReally interesting work from our neighbor Clare Smith @dukemedschool.bsky.social starting from CC mice and linking Ctsz to TB infection outcome as well as functional variation in human populations (UW, Case Western, Uganda) and expression in human granulomas (@charliejpyle.bsky.social)
- #Tuberculosis severity varies widely between people; why is this? This study uses the #CollaborativeCross mouse panel to identify the protease #cathepsin Z (CTSZ) as a conserved regulator of #TB outcomes via its influence on CXCL1 in mice & in humans @plosbiology.org 🧪 plos.io/4phwRA8
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- Pro: you get to work alongside Caroline et al. in The Premier molecular biology institution in South East Asia. Con: we're moving into the same building and I will have access to your snack cabinet.
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- TB archeology paper! 300 year old mummies from a population with ~80% Mtb infection had a huge increase of ectopic rib growth out of their lower neck bones. www.sciencedirect.com/science/arti...
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- Reposted by Stefan Oehlers🚀 Hiring in Paris: 1 PhD + 1 Postdoc for an ANR project on gut-brain biology in zebrafish (imaging, optogenetics). Leads: P. Hernandez (Curie) & G. Sumbre (ENS-IBENS). Start flexible 2026. Also M2 internships (Jan–Feb 2026). Details in the call. Please share! #PhDposition #Postdoc #Paris #Zebrafish
- Reposted by Stefan OehlersMy recent postdoctoral work is out today in @nature.com! We found that physical confinement makes melanoma cells more invasive and drug tolerant. Thanks to all who made this work possible @whitefishlab.bsky.social @mskcancercenter.bsky.social #NIH #NCI www.nature.com/articles/s41...
- Would @callmetube.bsky.social care to comment on their poor ranking in this opinion poll?
- Reposted by Stefan OehlersDid I just read the best abstract ever? 😁 www.biorxiv.org/content/10.1...
- Reposted by Stefan Oehlers📣 Ready to lead your own lab? NTU Singapore's Nanyang Assistant Professorship offers a 100% paid salary & a S$2.75M start-up package. We're visiting the US this Sept to recruit top talent. Meet us in NYC, Boston & more! #FacultyJobs #TenureTrack Register HERE: lnkd.in/gSy5qpA7
- Reposted by Stefan Oehlers🚨 Job alert 🚨 I’m recruiting two postdoctoral research associates to join my lab at KCL to study how #Klebsiella pneumoniae regulates virulence factor expression during infection! #klebclub Mol Micro: tinyurl.com/mtrwtx5e Infection: tinyurl.com/2s3u8ca2 Deadline: 21st September.
- The @astar-idlabs.bsky.social photon torpedo is ready for live firing again after an 8 month break. Look out IMCB neighbours @carolineleiwee.bsky.social
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