Hiren Joshi
Glycobioinfonaut, Associate Professor at the Copenhagen Center for Glycomics, University of Copenhagen. @hirenj.11 on Signal
- Reposted by Hiren Joshi"Structural analysis enabled us to convert Tn-specific mAbs into STn-specific mAbs through modification of VH complementarity-determining region 3, demonstrating the versatility of this approach" #glycotime 😎🧪 www.nature.com/articles/s41...
- Just a reminder that when the Nazis were marching in to Copenhagen, Neils Bohr chose to dissolve his medal rather than have any Nazi take possession of it.
- Reposted by Hiren JoshiAuthors use “Siglec-7 and -15…Fc chimera to demonstrate that CHST1-mediated 6-O-sulfation markedly enhanced binding to select O-glycoproteins, namely MAdCAM1, CD43, and PSGL-1” www.biorxiv.org/content/10.6...
- The robots are not coming for your jobs, but bullshitters with robots ARE competing for your jobs, and unless we decouple publishing metrics from career paths (financial gain), we are going to lose both careers and our capacity to share information. doi.org/10.1126/science.adw3000
- Reposted by Hiren JoshiA tribute to Stuart Kornfeld, pioneering #glycotime scientist whose work on mannose-6-phosphate receptor lysosomal trafficking (among many other contributions) was highly influential to our work 🫡 www.jci.org/articles/vie...
- There are so many quotes in this article that read as dystopian satire - but the worst has to be the overall idea that the one thing conservation efforts need is the Silicon Valley treatment. Pauli’s phrasing of “not even wrong” seems very apt here.
- Reposted by Hiren Joshi🚨 Are you into comp chem/biophys? Do you like glycobiology? Are you located around Freiburg Germany? Do you like me as a person? Want to see an open lecture about Computational Glycobiology/Biophysics in Freiburg, Germany, delivered by me?! 15 Dec, 17:15 HS Chemie @ Alberstrasse 21, 79104 Freiburg
- Includes Xylose, Galactose and maybe Mannose? So what is the hypothesis for why animals don’t use Ribose for anything else than RNA/DNA and matriglycan? It’s abundant, easy enough to make it seems, so why reserved for those molecules? www.nature.com/articles/s41...
- This is probably for an early life researcher or astrobiologist, but what are the preconditions for disaccharides? Did life have to wait for enzymes, or are they likely enough to form with a few catalysts lying around?
- Reposted by Hiren Joshi
- Last stretch for these positions, as the deadline for this is on Sunday!
- employment.ku.dk/faculty/?sho... Hi all! We’re hiring at our brand new Center for Glycocalyx Research, across all areas - but I am also looking for postdocs to join my group specifically!
- The submission pages for the positions are closed now, sorry if you missed out on applying!
- Hey @biorxivpreprint.bsky.social @altmetric.com , I haven’t been able to see the BlueSky metrics for preprints for a while now on the BioRxiv website, so I am missing out on all the salacious gossip about the preprints. Is this a known bug?
- Another bump for the postdoc and PhD positions still open at the center and postdoc specifically within my group (same link to apply). We’re looking for wet/dry lab, and I’m specifically after people who do magic with computers!
- employment.ku.dk/faculty/?sho... Hi all! We’re hiring at our brand new Center for Glycocalyx Research, across all areas - but I am also looking for postdocs to join my group specifically!
- Reminder: our postdoc and PhD positions are still open. We work across different areas (wet and dry lab), but I am especially after people with a computational biology, bioinformatics, pytorch whisperer kind of background. Protein design and OpenFold/AF also counts.
- employment.ku.dk/faculty/?sho... Hi all! We’re hiring at our brand new Center for Glycocalyx Research, across all areas - but I am also looking for postdocs to join my group specifically!
- We are looking to work on the next frontiers of structural biology, where we understand the shapes and arrangements of these dynamic machines on the cell surface. Can we decode the organisational language that coordinates all these machines? (We think, yes it is possible!).
- Reposted by Hiren JoshiFirst neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience Our latest in @natrevneuro.nature.com Link: rdcu.be/eMX3E @jeffcolgren.bsky.social @msarscentre.bsky.social
- Reposted by Hiren Joshi
- Pretty low-effort example of plagiarism here.
- Reposted by Hiren JoshiI have a PhD position available in my lab at the University of Freiburg!! If you, or someone you know, might be looking for a position using modeling and simulations to uncover secrets in (glyco-)protein structure/function relationships please take a look at our website! www.kearnslab.org
- It’s cool to see more stuff being built on top of Joshua Klein’s mzdata libraries. I’ve been playing around with a version that compiles down to WASM, which has been great to work with.
- Our universal peptide spectrum Annotator (and codebase rustyms) is now published in Analytical Chemistry, check it out! pubs.acs.org/doi/10.1021/... github.com/snijderlab/a... github.com/jspaezp/rust...