Laura Breimann
Genome Organization & Imaging Researcher | Postdoctoral Fellow at Harvard Medical School | Expert in Advanced Imaging, Image Analysis & Chromatin Biology
laurabreimann.github.io
- Reposted by Laura BreimannJoin us at CSHL for Quantitative Imaging: From Acquisition to Analysis—two weeks of advanced imaging, analysis, and hands-on labs with cutting-edge microscopes and open source software! 📅 April 6–21, 2026 📝 Applications due Friday Jan 30, 2026
- Reposted by Laura Breimann🚨 Alarm!!! 🚨 AI/ML course for microscopy image analysis!!! 🧐 In 2026 at Janelia (@hhmijanelia.bsky.social), no tuition, housing and meals provided! Isn’t that borderline unbelievable?!? 20 students, ~14 TAs and lecturers 🗓️ June 4-18 2026 ✍️ Jan 15 2026 ✍️ 🔁 pls!! www.janelia.org/you-janelia/...
- Reposted by Laura BreimannNew paper out! Combining single-objective light-sheet microscopy and time-resolved SPAD array detection, we massively accelerate fluorescence lifetime imaging (FLIM) compared to confocal FLIM, making FLIM applicable to 3D specimen such as organoids and embryos. www.nature.com/articles/s42...
- Reposted by Laura BreimannVery happy to share that starting in January, I will take on a new position as microscopic imaging facility leader and researcher at Der Simulierte Mensch (Si-M), a new joint institute by Charité and TUBerlin, which aims at advancing human model systems (e.g. organoids) for biomedical research.
- Reposted by Laura BreimannI think about this post every day 🧪
- Reposted by Laura BreimannJanelia is hosting a course on DL for bioimage analysis www.janelia.org/you-janelia/...
- Reposted by Laura BreimannWe are excited to welcome @fueyoraquel.bsky.social, @sedonamurphy.bsky.social, and @jmstein.bsky.social as new group leaders at our institute! Read more about their work: --> www.molgen.mpg.de/2025-10-31-n... All three are recruiting in the IMPRS PhD Call! --> www.molgen.mpg.de/IMPRSPhDproj...
- Reposted by Laura BreimannWe are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3
- Reposted by Laura BreimannOh yes-the one and only Robert Haase @haesleinhuepf.bsky.social From #GrandTheftAuto to the impact AI is having on #bioimaging. +the challenges of creating AI courses for bioimage analysis, & his unique perspective as a programmer-turned-biologist. Stream- bit.ly/microscopist... @globias.bsky.social
- Reposted by Laura BreimannWe're super excited to announce the entire lineup for the Fall season of Fragile Nucleosome Seminars, starting on Sept 10th at 1200 EDT / 1600 UTC with @gracebower.bsky.social and @creminslab.bsky.social! register here for the entire series: us06web.zoom.us/webinar/regi...
- Reposted by Laura Breimann
If you like transcription regulation and its mechanisms, this WIP list is for you. I'm sure I've forgotten lots of people, so don't hesitate to let me know so I can add you to the list. go.bsky.app/8vTgeXBat://did:plc:y655pqb5a3etnlz62iqgck5d/app.bsky.graph.starterpack/3lxhl3qh3ay2d - Reposted by Laura BreimannHello! Very excited to share our latest preprint, which is great news for us but terrible news for any diehard fans of PSNR and SSIM as image quality metrics in microscopy... (1/5) www.biorxiv.org/content/10.1...
- Excited that our paper was published in Science Advances 🧪 Great work by first author Merrick Pierson Smela who will carry this work forward in his new start-up!
- Wyss researchers have induced human stem cells to initiate meiosis – a key step in creating eggs and sperm – in the lab for the first time. This work was published in @science.org Advances.
- Link to the paper: www.science.org/doi/10.1126/...
- Reposted by Laura Breimann🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. www.biorxiv.org/content/10.1...
- Reposted by Laura BreimannWhat better way to launch our new account with the publication of @jmstein.bsky.social latest paper from the lab! 🧪 Check out the 🧵 below to learn more about tkPAINT and how we use it to image proteins, DNA, and RNA in the nucleus using DNA-PAINT.
- (1/n) DNA-PAINT imaging inside the nucleus at single antibody resolution using TIRF? Ultrathin sectioning makes it happen! Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org! doi.org/10.1073/pnas... 👇🧵
- Excited that tkPAINT is finally published! 🔬 Check out the latest version at @pnas.org and see this thread from @jmstein.bsky.social for the overview! Thank you for this fun collaboration! 🤗
- (1/n) DNA-PAINT imaging inside the nucleus at single antibody resolution using TIRF? Ultrathin sectioning makes it happen! Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org! doi.org/10.1073/pnas... 👇🧵
- Reposted by Laura BreimannLooking for an opportunity to work on cutting super-resolution microscopy and AI? There's still time to apply to the two positions!
- Reposted by Laura Breimann(1/n) A simple, ultrastable, and cost-effective oxygen-scavenging system for long-term DNA-PAINT imaging Please check out our new study on the benefits of sodium sulfite as oxygen scavenging system for DNA-PAINT. 👇🧵 #SuperResolution #DNAPAINT #SMLM #Microscopy
- Reposted by Laura BreimannThis seems like a really important paper comparing chromosome tracing methods, demonstrating that classical denaturing DNA-FISH and chromosome tracing leads to substantial distortion of 3D genome structure, likely due to the high-temperatures involved (70-90C): www.nature.com/articles/s41...
- Reposted by Laura BreimannDo you like developing new AI vision methods for microscopy image analysis? You love theory & implementation? 1 week left to apply for a fully funded PhD position in our lab in Dresden 🇩🇪! Topics: object detection/tracking, multimodal models & more. DM/email for details! #PhD #AcademicJobs #GPUsgoBrr
- Reposted by Laura BreimannNature Methods is hiring! We are seeking a new editor with expertise in microscopy, imaging technology, and/or cell biology. The position is available in NYC/Jersey City or Shanghai/Beijing on a hybrid working model. Apply by August 3! springernature.wd3.myworkdayjobs.com/SpringerNatu...
- Reposted by Laura BreimannHow to represent genomes in 3D? In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅 👉🏼 genomebiology.biomedcentral.com/articles/10....
- Reposted by Laura BreimannOur new preprint is out on bioRxiv! We show that restoring rigidity sensing via Tpm2.1 is not enough to trigger anoikis in cancer cells, thanks to compensatory AKT signaling and cell–cell adhesion. With Anat, Nehal, and in memory of Mike Sheetz. www.biorxiv.org/content/10.1...
- I can’t take credit for this alone, but still a special moment ✨
- Reposted by Laura BreimannCome and work with us! Super exciting and relevant projects! Become an #AI pro and do something positive for the 🌍! 👩🎓 🧑🎓 If you know someone who might be interested… please repost and/or forward this! 🙏
- 🚀 Fully-funded #PhD opportunity in Computational Biology with our @florianjug.bsky.social Group through Politecnico of Milan DADS programme! Co-supervision by Francesca Ieva. 🧬 Use #AI to decode complex biological data across scales. Apply by 9 July 👉 humantechnopole.it/en/news/1-fu...
- Reposted by Laura Breimann🚨 New #preprint alert! We're excited to share our latest work: "Single-Allele Chromatin Tracing Reveals Genomic Clustering of Paralogous Transcription Factors as a Mechanism for Developmental Robustness in T Cells"🔗 tinyurl.com/4ve26tbd
- Reposted by Laura BreimannAre you looking to advance your bioimage analysis skills? Then don't miss the deadline for #EMBOBioImage 🔬✨ 📩 Apply by 4 June ➡️ s.embl.org/bia25-01-bl 🗓️ 14 – 19 September 📍 EMBL Heidelberg and Virtual
- Reposted by Laura BreimannExtensive differences observed in 3D genome structure between homologous heterozygous chromosomes revealed by Genome Architecture Mapping #GAM in the @apombo1.bsky.social lab ➡️ www.embopress.org/doi/full/10....
- I am excited to be one of this year's Leadership Academy fellows #LSA9! I am looking forward to meeting the other fellows and learning about the program. It is also a great time to visit Germany 🇩🇪 and see which opportunities exist for my research and me!
- #Leadership isn’t a buzzword. It’s a #responsibility. Our GSO Leadership Academy 9 brings together 25 researchers from 10 countries to rethink what leadership in science means - and how it can strengthen institutions, communities, and futures. #LSA9 #GSOLA 1. phase in Berlin - starting in July!
- Reposted by Laura BreimannI’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...
- Reposted by Laura BreimannWe are proudly hosting 𝐃𝐫. 𝐓𝐚𝐥𝐥𝐞𝐲 𝐋𝐚𝐦𝐛𝐞𝐫𝐭 @talley.codes (CITE, Harvard Medical School): 𝐒𝐢𝐦𝐮𝐥𝐚𝐭𝐢𝐧𝐠 𝐫𝐞𝐚𝐥𝐢𝐬𝐭𝐢𝐜 𝐥𝐢𝐠𝐡𝐭 𝐦𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐲 𝐢𝐦𝐚𝐠𝐞𝐬 𝐮𝐬𝐢𝐧𝐠 𝐦𝐢𝐜𝐫𝐨𝐬𝐢𝐦 When: 𝐌𝐚𝐲 𝟐𝟗𝐭𝐡 @ 𝟏𝟏 𝐚𝐦 𝐄𝐃𝐓 (Boston time) Join us on Zoom! harvard.zoom.us/j/9762343464...
- Reposted by Laura BreimannOne week to go before the applications close on the 6th May! What: Train-the-trainer in BioImage Analysis When: 13th June 2025 Where: London, UK More info: franciscrickinstitute.github.io/Train_the_tr...
- Reposted by Laura BreimannHow can AI help you to analyze your microscopy images? Find out at the "Machine Learning for Microscopy Image Analysis" course at the @mblscience.bsky.social in Woods Hole from Aug 22-Sep 6! Applications are due 🚨 April 30 🚨 Read on for more! 👇 www.mbl.edu/education/ad...
- Looking for a Postdoc position in 3D genome architecture? This is a great opportunity:
- 🧬 We’re hiring a Postdoc in Genomic Data Science @IITalk! Join us to explore 3D genome architecture and RNAs using imaging, genomics & ML 💻🔬🐠 💼 Up to €45k/year ✅ PhD + Python/ML skills ➕ Experience with omics, imaging, or modelling = plus 📍 Genoa 🌊☀️ 📧 irene.farabella@iit.it 🔗 tinyurl.com/6z52jhr9
- Reposted by Laura Breimann🚨 Excited to announce the 2nd Spatial Genome Organisation Conference! #SGO25 📅 Oct 31–Nov 3, 2025 | 📍 Riviera Maya, Mexico 🪑 Chairs: @altmeyerlab.bsky.social, @chiololab.bsky.social, @karimmekhail.bsky.social 🔗 Registration: fusion-conferences.com/conference/188 Please 🔄 ❤️
- Reposted by Laura Breimann💻 Announcing the Boston Bioimage Analysis Course — BoBiAC! Join us this July at Harvard Medical School in Boston for a 6-day deep dive into bioimage analysis with Python, hosted by the IAC and CITE. Apply by May 16th, 2025!
- Happy to share the publication of another collaboration with the Chekulaeva lab at @mdc-berlin.bsky.social. This work uses patient-derived iPSC models to study the molecular mechanisms of neurodegenerative diseases like ALS: academic.oup.com/narmolmed/ad...
- Reposted by Laura BreimannWhy does National Institutes of Health funding matter? It’s the fuel to find cures for: - Cancer - Alzheimer’s - Cystic Fibrosis - Pediatric Cancer - ALS - MS - Parkinson’s Trump tried to cut it, but thanks to AG Campbell, a judge blocked the cuts. This is why we fight.
- My German election ballot only arrived today, a long shot but is anyone traveling from Boston to Berlin today who could take it? Any leads @germanyinboston.bsky.social ?
- Reposted by Laura BreimannFriendly reminder to get your free Covid tests before they throw them away. Covidtests.gov wapo.st/42VLGQh
- Reposted by Laura BreimannDNA-PAINT imaging with hydrogel imprinting and clearing biorxiv.org/content/10.1101/202…
- Reposted by Laura BreimannAfter a long journey, Segment Anything for Microscopy is now published in Nature Methods! We significantly improve SAM for interactive and automatic segmentation in light and electron microscopy and build a user-friendly tool. www.nature.com/articles/s41...
- Reposted by Laura Breimann🔬🎤 As pre-announced a few days ago... please let us proudly present to you: 𝑴𝒊𝒄𝒓𝒐𝕊𝒑𝒍𝒊𝒕 - your ticket to imaging more, imaging more gentle, and/or imaging more efficient. 🔬 doi.org/10.1101/2025... Like ❤️, repost 🔂, and most importantly... please send feedback ✉️ our way! 🙏
- Immagine you could image two cellular structures in the same fluorescent channel and still reliably get them separated afterwards… What would you do with this? Now… what would you do if that also worked with 4 structures at once? 👇 #MicroSplit #preview🧵
- Reposted by Laura BreimannExcited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...
- Reposted by Laura BreimannWe often speak about chromatin as being accessible or inaccessible, but what does it mean? We wrote a short review on this, 🔬 focused: sciencedirect.com/science/arti... A big thank you to Tom Fillot for his efforts on this and to @hansen_lab @marcelonollmann for their help as editors.
- Reposted by Laura BreimannCongrats, Ana Pombo! The #mdcBerlin scientist receives Germany's most important science prize: the Gottfried Wilhelm Leibniz Prize by the German Research Foundation #DFG. About @apombo1.bsky.social and her work: www.mdc-berlin.de/news/news/an... #mdcBIMSB @www.helmholtz.de @humboldtuni.bsky.social
- Reposted by Laura BreimannAnnouncing the next EMBO Chromosome Segregation and Aneuploidy Meeting! Italy 2025. Please register and join us for another exciting and friendly meeting in a beautiful location meetings.embo.org/event/25-ane...
