Ting Wu Lab
We are the Ting Wu Lab @ HMS. Our laboratory studies how chromosome behavior and positioning influence genome function, with implications for gene regulation, genome stability, and disease.
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- Reposted by Ting Wu LabA major output of the 4D Nucleome project appeared today. This is the joint effort of many scientists working together and (publicly) sharing data and results for several years. We hope this is of interest to many genome biologists! www.nature.com/articles/s41...
- Reposted by Ting Wu LabIn this episode we talked with @andersshansen.bsky.social from MIT about his work on the impact of 3D genome structures on gene expression and advanced techniques like Region Capture Micro-C for mapping genome organisation. #podcast #epigenetics Listen here: activemotif.com/podcasts-and...
- Reposted by Ting Wu LabExcited that our paper was published in Science Advances 🧪 Great work by first author Merrick Pierson Smela who will carry this work forward in his new start-up!
- Wyss researchers have induced human stem cells to initiate meiosis – a key step in creating eggs and sperm – in the lab for the first time. This work was published in @science.org Advances.
- Reposted by Ting Wu LabNew preprint from @apombo1.bsky.social’s lab on gene regulation; insights into super-enhancers and their role in establishing complex regulatory networks of cell-type specific interactions with other enhancers and genes with specialized cellular functions 🧪🧬 www.biorxiv.org/content/10.1...
- Reposted by Ting Wu LabExcited that tkPAINT is finally published! 🔬 Check out the latest version at @pnas.org and see this thread from @jmstein.bsky.social for the overview! Thank you for this fun collaboration! 🤗
- (1/n) DNA-PAINT imaging inside the nucleus at single antibody resolution using TIRF? Ultrathin sectioning makes it happen! Grateful to share my postdoctoral work introducing “tomographic & kinetically-enhanced DNA-PAINT” or in brief: tkPAINT. Out in @pnas.org! doi.org/10.1073/pnas... 👇🧵
- Reposted by Ting Wu Lab🚨New preprint from the lab🚨 🧬 What keeps certain chromatin domains anchored at the nuclear periphery? Our new genome-wide HiDRO screen uncovers a key role for RNA-binding protein hnRNPK. www.biorxiv.org/content/10.1...
