Golnaz Vahedi
Department of Genetics, Institute for Immunology and Immune Health, Epigenetics Institute, University of Pennsylvania
vahedilab.com instagram.com/vahedilaboratory/
- Didn’t get the grad school interview you wanted yet? Turn this year into a launchpad. The Vahedi Lab @Penn is hiring a Research Specialist A/B — an ideal role for undergrads & recent grads aiming for PhD/MD-PhD programs. 🧬 Immunology + genomics. Apply here: lnkd.in/e8uT_hif
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- Reposted by Golnaz Vahedift. @yeqiaoz.bsky.social, N. Burget, Tobias Friedrich, @faryabi.bsky.social (@pennpathlabmed.bsky.social), @atishayjay.bsky.social (Bioeng), S. Yoon & @vahedilab.bsky.social (@penngenetics.bsky.social) @pennepigenetics.bsky.social @i3h-upenn.bsky.social www.nature.com/articles/s41...
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- Beyond excited to share the collaborative work with @faryabi.bsky.social led by stars Yeqiao Zhou and @atishayjay.bsky.social; Walking along thousands of chromosomes has shown us just how essential it is to measure chromatin fiber geometry to truly understand enhancer biology. tinyurl.com/2st3afwf
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- Reposted by Golnaz VahediHow to keep in step when your (protein) partner speeds up… Here we investigated the adaptive remodeling of a protein-protein interaction surface essential for telomere protection. Congrats to whole team! www.science.org/doi/10.1126/...
- I am very excited to share our collaborative work on multiome profiling of gene expression and chromatin accessibility of more than 1 million immune cells in pancreatic lymph nodes and spleens in human type 1 diabetes in @sciimmunology.bsky.social scim.ag/4o12TOZ
- We are also beyond grateful to @sciimmunology.bsky.social editorial team and also the peer review process helping us improve the quality of our study
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- In this article, I share my perspective on leveraging AI and single-cell profiling to predict type 1 diabetes. It’s great to see the diverse insights contributed by other experts in the field: www.nature.com/articles/s42...
- Reposted by Golnaz VahediThrilled to share my promotion to Associate Professor with tenure at @pitt-immunology.bsky.social! Huge thanks to my incredible lab, collaborators, department, colleagues, family & friends. Science is a team effort, and I'm so proud of our work & excited for what's next! Stay tuned!
- Congratulations to Dr. Amanda Poholek @poholeklab.bsky.social for her promotion to Associate Professor with tenure! Learn more about Dr. Poholek and her research: buff.ly/q14wey8
- The Vahedi Lab is seeking a highly motivated Research Specialist A/B to join our dynamic research group studying the mechanisms of immune regulation. Apply here: wd1.myworkdaysite.com/recruiting/u...
- Reposted by Golnaz VahediExcited to finally present the lab's latest work in defining candidate causal genetic variants that drive autoimmune diseases and their effects on primary human T cell expression and function! www.nature.com/articles/s41...
- New preprint in collaboration with the Faryabi lab: Optical Looping Interactive Viewing Engine (OLIVE), a web-based tool designed for high-throughput chromatin tracing data that functions similarly to genome browsers. If you work with these data, give a try: www.biorxiv.org/content/10.1...
- 🚨 New #preprint alert! We're excited to share the latest work from the brilliant Sora Yoon: "Inference of multi-enhancer interactions in T lymphocytes using Hi-Cociety"🔗 www.biorxiv.org/content/10.1...
- 🚨 New #preprint alert! We're excited to share our latest work: "Single-Allele Chromatin Tracing Reveals Genomic Clustering of Paralogous Transcription Factors as a Mechanism for Developmental Robustness in T Cells"🔗 tinyurl.com/4ve26tbd
- This study was a huge team effort, led by the brilliant @atishayjay.bsky.social in close collaboration with Yeqiao Zhao in the @faryabi.bsky.social Lab, with key contributions from @arjunraj.bsky.social, whose Nimbus image analysis tool was essential.
- Sometimes you only need to focus on good news: www.nytimes.com/2025/05/15/h...
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- Reposted by Golnaz VahediCongratulations to Katalin Karikó (@PennNSG), Virginia Lee (@pennpathlabmed.bsky.social), @ejohnwherry.bsky.social (@PennSysPharmATT) & Mark Devlin (@physatpenn) on their election to @nasonline.org! tinyurl.com/5eehdtms
- Reposted by Golnaz VahediSuper excited to be launching NimbusImage.com! Cloud-based image analysis to democratize machine learning! Documentation here! docs.nimbusimage.com
- Congrats to Atishay and Carlos for their review article on the epigenetics regulation of T cells: www.nature.com/articles/s41...
- Reposted by Golnaz VahediAccuracy of gene regulatory network inference is increased by combining multiome single-cell and atlas-scale bulk data go.nature.com/43YySqO rdcu.be/ebBio
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- Reposted by Golnaz VahediDisease diagnostics using machine learning of B cell and T cell receptor sequences www.science.org/doi/10.1126/... TL;DR: BCRs ARE ALL YOU NEED! (Well actually .... keep reading) 1/
- Reposted by Golnaz VahediResearchers at Fred Hutch have discovered an overlooked mechanism driving aggressive breast and brain tumors involving genes so ancient — more than 2 billion years old — that they fly under the radar of standard genetic sequencing methods. 1/9 www.science.org/doi/10.1126/...
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- Reposted by Golnaz VahediThis will kill science in the US. This is how China wins. Why is this not on the news? Why are people not more upset about this? grants.nih.gov/grants/guide...
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- Go Birds!
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- Reposted by Golnaz VahediIf you’ve been directly impacted by a pause or cancellation of an NIH study session, we @forbes.com would like to talk to you
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- Reposted by Golnaz VahediHere is link to Shixin's new paper: www.science.org/doi/epdf/10....
- Reposted by Golnaz VahediI’m excited to share our latest study led by @giuliapasquesi.bsky.social out today in @cellpress.bsky.social , uncovering a new way transposons have been repurposed for human interferon signaling! Read on for a thread on cryptic splice variants, decoy receptors, and viruses (1/N) 👇🧵 #TESky 🧪
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- Reposted by Golnaz VahediThere are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research. A Place of Joy.
- Reposted by Golnaz VahediTET2 regulates early & late transitions in exhausted CD8+ T cell differentiation & limits CAR T cell function ft. Alexander Dimitri, Gregory Chen, @JoeFraietta (@PennMicro/ @penncancer.bsky.social), @amylizbaxter (@PennSysPharmATT) & Martha Jordan (@PennPathLabMed) www.science.org/doi/10.1126/...
