Kilchert lab
We are an RNA biology lab @JLU Giessen interested in RNA quality control, RNP remodelling and post-transcriptional gene regulation - branching into chromatin
- Reposted by Kilchert lab🧪 My lab has an opening for a postdoc position soon! Please share/get in touch!
- 📣NuQuest consortium update: Our first joint publication is out!Review on quiescence—A milestone for our initiative laying out the scientific groundwork & collaborative vision for our MSCA-DN application coordinated by @jlugiessen.bsky.social 1/n www.mdpi.com/3700996 #NuQuest #MSCA #DoctoralNetwork
- This was a joint effort between yeast and mammalian experts @thebraunlab.bsky.social @bulutkarslioglu.bsky.social @angela-taddei.bsky.social, D. Włoch-Salamon and co-workers, with great support from additional NuQuest members and @Biomol_MDPI. 4/n @pombase.bsky.social @yeastgenome.bsky.social
- Reposted by Kilchert labHappy to announce our RTG 2355 International Conference “Regulatory landscapes of RNA: From code to control”, Sept 14-16, 2026 in Giessen, Germany. Topics cover #RNA as messenger, recruiting platform, sponge, regulator & sensor. 👉tinyurl.com/rtg2355conf Save the date – registration opens May 1!
- Congrats to Fabienne and co-workers!
- Happy to share the work by Fabienne Becker et al in #NAR, showing how yeast Tho1-CTD stimulates helicase activity of Sub2, homologue of human DDX39B/UAP56, by promoting Sub2 oligomerization on RNA. The scaffolding mechanism is shared across species: academic.oup.com/nar/article/...
- Reposted by Kilchert lab📣 Our lab is looking for a PhD student to join us in exploring RNA biology! Details in the announcement. Feel free to reach out with any questions—and please RT!
- Reposted by Kilchert labPostdoc positions in structural biology of RNA processing complexes. An ERC-funded position will dissect pre-mRNA processing pathways in the infective organism Trypanosoma brucei. An ANR-funded position will characterise large complexes in RNA modification. Details: tinyurl.com/postdoc-RNA-...
- Reposted by Kilchert lab#Postdoc position - at the University of Marburg (Germany), funded within our ERC Advanced Grant "C-SWITCH" Focus: CTP-dependent molecular switches as a new principle of cellular regulation in bacteria (including bacteriophages) Apply by 04 May: stellenangebote.uni-marburg.de/jobposting/2...
- Reposted by Kilchert labCongratulations to Anne Spang @spanglab.bsky.social for being elected as a new #AAASFellow by @aaas.org ! The world’s largest scientific society recognizes her outstanding contributions to the field of cell #biology and #biochemistry. @unibas.ch www.biozentrum.unibas.ch/news/detail/...
- Reposted by Kilchert labI'm excited to share our latest publication on co-transcriptional RNA folding in a eukaryote! Great work by Leo Schärfen with collaboration from Isaac Vock and Matt Simon! @leoschaerfen.bsky.social @mattdsimon.bsky.social Take a peek here authors.elsevier.com/a/1kpxo_Oylr...
- Reposted by Kilchert labA nearly 9 year effort to design and implement new CLIP-based technologies to define multimeric protein assemblies on RNA. Enables ‘watching’ of RNP assemblies inside living cells Special congrats to Luca Ducoli, Brian Zarnegar, and Paul Khavari @nature.com www.nature.com/articles/s41...
- Reposted by Kilchert labRNA Salon in mRNA Translation We have an exciting lineup with Keynote by: Marvin Tanenbaum (Hubrecht/ Delft) Please RT @goetheuni.bsky.social @cpi-exstra.bsky.social
- Reposted by Kilchert lab📣 We are advertising for a postdoc to join our team at the University of Edinburgh! Our lab studies gene regulatory mechanisms in development, and how genetic changes may impact these processes to alter development and shape human craniofacial form and function 🧬🧪
- Reposted by Kilchert labCool! #MTR4 #RNADecay #RNA #RNAExosome The #nuclear #exosome co-factor #MTR4 shapes the #transcriptome for #meiotic initiation Li Zhang, Jianshu Wang, Zhidong Tang, Zhen Lin, Ruibao Su, Naijing Hu, Yao Tang, Gaoxiang Ge, Jing Fan, Ming-Han Tong, Yuanchao Xue, Yu Zhou & Hong Cheng rdcu.be/ed5WM
- Reposted by Kilchert lab[Not loaded yet]
- Super proud! Congrats and well done!
- Another Dr. from our RTG - Ebru Aydin from @kilchertlab.bsky.social successfully defended her thesis yesterday. Congratulations, Ebru! 🎓And a great party, too 🥳🍾🥂
- Reposted by Kilchert labCongratulations to RTG2355-member Jennifer Kothe from Elena Evguenieva-Hackenberg's lab for successfully defending her dissertation - well done, Jenni! 🎓🥳 (And please note the DNA, RNAP, RNA and ribosome on the cake!)
- Reposted by Kilchert labExcited to share the work of Jennifer Kothe et al suggesting a mechanism to be used by bacteria for fine-tuning gene expression according to ribosome availability and translation efficiency: www.biorxiv.org/content/10.1...
- Reposted by Kilchert labOpen PhD position in our RTG2355 - great diversity in topics, invited speakers, retreats and symposia, workshops, soft skill courses - and very nice people!
- Interested in RNA biology, especially mRNA processing and export from nucleus to cytoplasm? We are looking for an enthusiastic PhD student to investigate the RNA-binding proteins Sub2 and Tho1 🧪🧫🔬 More details and instructions on how to apply: www.uni-giessen.de/de/ueber-uns...
- Reposted by Kilchert lab[Not loaded yet]
- Reposted by Kilchert labSecond call for a postdoc position in my lab. Please read more and apply here: mbg.au.dk/aktuelt/ledi...
- Reposted by Kilchert labWe are excited to share the work of Nataliia Stefanyshena who showed that maintenance of an optimal Mex67 level in nuclear mRNPs is required for efficient mRNA export: www.biorxiv.org/content/10.1...
- Reposted by Kilchert labInterested in RNA biology, especially mRNA processing and export from nucleus to cytoplasm? We are looking for an enthusiastic PhD student to investigate the RNA-binding proteins Sub2 and Tho1 🧪🧫🔬 More details and instructions on how to apply: www.uni-giessen.de/de/ueber-uns...
- Reposted by Kilchert lab[Not loaded yet]
- Reposted by Kilchert labThe rise and shine of yeast optogenetics Full text: onlinelibrary.wiley.com/doi/10.1002/... #yeast #saccharomyces #microbiology
- Reposted by Kilchert lab
This work is not only an amazing resource for the community, it is also a total masterclass in code reusability, data FAIRness and reproducibility. Hopefully, this is the future!- www.sciencedirect.com/science/arti... I am very excited to share our latest work on the protein and chromatin interactomes of transcription factors! 🧬 Huge thanks to everyone who contributed, especially @csoneson.bsky.social and @mbstadler.bsky.social for driving this story with me! 🙌
- Reposted by Kilchert lab𝐇𝐨𝐰 𝐝𝐨 𝐜𝐞𝐥𝐥𝐬 𝐫𝐞𝐦𝐞𝐦𝐛𝐞𝐫 𝐰𝐡𝐨 𝐭𝐡𝐞𝐲 𝐚𝐫𝐞 𝐚𝐟𝐭𝐞𝐫 𝐃𝐍𝐀 𝐫𝐞𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧? Our new study “Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability” is out in 𝘚𝘤𝘪𝘦𝘯𝘤𝘦 𝘈𝘥𝘷𝘢𝘯𝘤𝘦𝘴. Led by @lleonie.bsky.social @biranalva.bsky.social 🧵 More below👇
- Reposted by Kilchert labPhD position vacant in the lab. Please spread the news. Study topic: Mammalian nuclear RNA production and turnover systems. Learn more about the lab here: www.mRNP.au.dk
- Reposted by Kilchert lab[Not loaded yet]
- Reposted by Kilchert lab[Not loaded yet]
- Reposted by Kilchert lab[Not loaded yet]
- Reposted by Kilchert labPomBase is GBC Global BioData Resource of the week www.linkedin.com/pulse/pombas...
- Reposted by Kilchert labCome and join us for the RMU RNA salon "Translation" in Frankfurt! Tuesday, April 1st 2025, 12:30 – 6:00 pm at Medical Campus Niederrad, Building 22 – HS22-2. Please register here: bit.ly/13_RMU_RNA_S... Thank you @rnasociety.bsky.social and #lexogen for funding!
- Reposted by Kilchert labWe are recruiting! Center for Gene Expression has 2 or more open positions for PhDs @ucph.bsky.social. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com). It's a wonderful city and amazing research environment. Deadline March 6. jobportal.ku.dk/phd/?show=16...
- Reposted by Kilchert labWe are pleased to announce registration for RNA 2025 - the 30th Annual Meeting of the RNA Society - is now open! www2.rnasociety.org This year’s meeting will be held at the beautiful Town and Country Resort & Convention Center in sunny San Diego, California, USA from May 27th - June 1st, 2025.
- Reposted by Kilchert lab[Not loaded yet]
- Reposted by Kilchert labExciting opportunity! Max Planck Institute for Terrestrial Microbiology is looking for a Head of the DNA-Biofoundry MaxGENESYS. Join us in vibrant #Marburg - apply by 15 February 2025. #ScienceJobs #SyntheticBiology #Biofoundry @maxplanck.de
- Reposted by Kilchert labOur newest publication is out! N-6-methyladenosine (m6A) promotes the nuclear retention of mRNAs with intact 5′ splice site motifs www.life-science-alliance.org/content/8/2/... Here is a short 🧵: (1/n)
- Reposted by Kilchert labCheck out our recent work on CDS #m6A mediated RNA decay (CMD)! Decay relies on ribosome pausing at m6A containing codons. Great collab with the Zarnack lab & colleagues. Thank you @uniwuerzburg.bsky.social , @imbmainz.bsky.social and RMap🥳 www.cell.com/molecular-ce...
- Reposted by Kilchert labSince April, we have been busy curating pathways using GO-CAM pathway modelling. So far, 466 proteins (33 pathways) have been modelled. We have modelled signalling pathways, metabolic pathways, and other processes. The full list is here: www.pombase.org/documentatio..., and will increase weekly!
- Reposted by Kilchert labThe GfG is delighted to reconnect with everyone here on Bluesky! We're excited to announce our upcoming symposium, "Epigenetics & Chromatin", taking place September 24–26 in Giessen, Germany. Stay tuned for more details! (... and become a member of the GfG...!)
- Reposted by Kilchert labCongratulations to Anne Spang for receiving the renowned Lelio Orci Award. The award honors her pioneering work in intracellular organization and her research achievements in Cell Biology. @unibas.ch www.biozentrum.unibas.ch/news/detail/...
- Reposted by Kilchert lab
- Reposted by Kilchert labHello Bluesky, Caliskan Lab is hiring! Our new Lab in Uni Regensburg has open #ERC funded PhD and postdoctoral positions (with long term employment opportunities) in viral #RNA-protein interactions regulating #translation, #transcription, #recoding and #single-molecule-analysis #RNA
- Also including JLU Giessen
- Reposted by Kilchert labNow out on bioRxiv: our collaboration with Simone Heber, Anne Ephrussi and Jeff Chao reveals how Staufen interacts with the kinesin adapter aTm1 to localize oskar mRNA in #Drosophila oocytes, modulating kinesin-1 dependent mRNA transport. #RNAsky #RNA doi.org/10.1101/2024...
- Reposted by Kilchert labIs chromatin ordered or disordered? It all depends on the linker DNA length. Check our latest work with Mike Rosen and Sy Redding. We explore how changes in linker DNA length (as small as 1 bp) fine-tune chromatin structure, between order and disorder, and the properties of chromatin droplets
- Nucleosome Spacing Can Fine-Tune Higher Order Chromatin Assembly biorxiv.org/content/10.1101/202…
- Reposted by Kilchert labPhosphorylation of a nuclear condensate regulates cohesion and mRNA retention #RNAbiology #RNAlocalization www.nature.com/articles/s41...
- Out in @naturecomms.bsky.social: Kris's work showing that elongation factor Spt5 suppresses DNA-directed, T tract-dependent RNAPII termination but promotes the torpedo-dependent mechanism - from the Vasiljeva lab @oxfordbiochemistry.bsky.social (not on bsky). www.nature.com/articles/s41...
- Reposted by Kilchert lab[Not loaded yet]
- Reposted by Kilchert lab[Not loaded yet]
