Leonie Kollenstart
Postdoc in the lab of Anja Groth at the Danish Cancer Institute in Copenhagen. Studying chromatin replication and parental histone recycling♻️ to understand epigenetic memory and cell fate. Lover of electronic music. She/her
- Reposted by Leonie KollenstartCongratulations to @groth-anja.bsky.social on receiving the Novo Nordisk Foundation Jacobæus Prize 🏆 we’re proud to see Anja's mentorship, leadership, & pioneering work in epigenetic cell memory getting top recognition 👏 celebrating the contributions of past & present lab members to this work too 🥳
- Reposted by Leonie KollenstartOur latest collaboration with the talented Susi @sbantele.bsky.social and Jiri Lukas is out now @science.org 🤩. We reveal the hidden price for DNA repair, with potential implications for genome function, gene therapy and ageing👇
- 𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
- Reposted by Leonie Kollenstart𝗖𝗮𝗻 𝗰𝗲𝗹𝗹𝘀 𝗲𝘃𝗲𝗿 𝘁𝗿𝘂𝗹𝘆 𝗿𝗲𝗰𝗼𝘃𝗲𝗿 𝗳𝗿𝗼𝗺 𝗗𝗡𝗔 𝗱𝗮𝗺𝗮𝗴𝗲?Excited to share our new study “Repair of DNA double-strand breaks leaves heritable impairment to genome function”, revealing DNA repair’s hidden cost, out now @science.org tinyurl.com/5n6zw3ye. Led by @sbantele.bsky.social and Jiri Lukas.🧵👇1/n
- Reposted by Leonie KollenstartSome (+)ve news to lighten another heavy weekend: our latest preprint (c/o Mattiroli + Ramani labs) is up! www.biorxiv.org/content/10.1... A tour-de-force by 1st authors Bruna Eckhardt & @palindromephd.bsky.social, focusing on chromatin replication. RTs welcome; tweetorial in 3,2...(1/n)
- Reposted by Leonie KollenstartWe have lift off!! 🚀 Yesterday was the official opening of EpiC! The DNRF Center for Epigenetic Cell Memory at the Danish Cancer Institute! Our EpiC team with director Anja Groth @groth-anja.bsky.social, were joined by Jesper Fisker, CEO @cancer.dk & Niels Mejlgaar, CEO @dg.dk to celebrate 🎉
- Reposted by Leonie KollenstartPostdoc positions open in my lab (Francis Crick Institute) to study 1. initiation of DNA replication. 2. chromatin replication/epigenetic inheritance. Great for biochemists, biophysicists and cryo-EM/cryo-tomography scientists. Deadline 3 August 2025. crick.wd3.myworkdayjobs.com/External/job...
- Reposted by Leonie Kollenstart🧬Postdoc position alert! 🚨 We're hiring a postoc in Computational Modeling of Epigenetic Inheritance at the Hubrecht Institute (Alexander van Oudenaarden, Utrecht 🇳🇱) & Danish Cancer Institute (Anja Groth, Copenhagen 🇩🇰). Come work in our collaberative team of top scientists shorturl.at/avBBy
- Reposted by Leonie Kollenstart🚨 Postdoc wanted (🇳🇱NL based) for our exciting collaboration with the lab of Alexander van Oudenaarden @hubrechtinstitute.bsky.social in Utrecht, with collaborative visits to our lab Copenhagen 🇩🇰. We seek a computational scientist to model epigenetic inheritance, see more below 👇!
- 🧬Postdoc position alert! 🚨 We're hiring a postoc in Computational Modeling of Epigenetic Inheritance at the Hubrecht Institute (Alexander van Oudenaarden, Utrecht 🇳🇱) & Danish Cancer Institute (Anja Groth, Copenhagen 🇩🇰). Come work in our collaberative team of top scientists shorturl.at/avBBy
- Reposted by Leonie KollenstartA few days left to apply for exciting PhD and Postdoc opportunities in wonderful Copenhagen and join our efforts in understanding Epigenetic Cell Memory.
- 🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
- Reposted by Leonie Kollenstart𝐍𝐞𝐰 𝐦𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐭𝐢𝐜 𝐢𝐧𝐬𝐢𝐠𝐡𝐭𝐬 𝐢𝐧𝐭𝐨 𝐭𝐡𝐞 𝐫𝐞𝐠𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐡𝐢𝐬𝐭𝐨𝐧𝐞 𝐬𝐮𝐩𝐩𝐥𝐲! Excited to share our latest collaboration led by tkjeong.bsky.social and ciaranfrater.bsky.social! Structural determination of the histone chaperone ASF1 and its regulator CODANIN-1 uncovers how CODANIN-1 counters ASF1 activity. 🧵👇
- Excited to share my main postdoctoral work and our new insights into epigenome inheritance! Huge thanks to an amazing team—especially Alva Biran (@biranalva.bsky.social) & Anja Groth (@groth-anja.bsky.social). 🧵👇
- 𝐇𝐨𝐰 𝐝𝐨 𝐜𝐞𝐥𝐥𝐬 𝐫𝐞𝐦𝐞𝐦𝐛𝐞𝐫 𝐰𝐡𝐨 𝐭𝐡𝐞𝐲 𝐚𝐫𝐞 𝐚𝐟𝐭𝐞𝐫 𝐃𝐍𝐀 𝐫𝐞𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧? Our new study “Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability” is out in 𝘚𝘤𝘪𝘦𝘯𝘤𝘦 𝘈𝘥𝘷𝘢𝘯𝘤𝘦𝘴. Led by @lleonie.bsky.social @biranalva.bsky.social 🧵 More below👇
- Moving-in day at the Danish Cancer Institute! Look at this pristine, untouched lab 🤩
- Want to join us in 𝐂𝐨𝐩𝐞𝐧𝐡𝐚𝐠𝐞𝐧, 𝐃𝐞𝐧𝐦𝐚𝐫𝐤? 🇩🇰 Our new 𝐂𝐞𝐧𝐭𝐞𝐫 𝐟𝐨𝐫 𝐄𝐩𝐢𝐠𝐞𝐧𝐞𝐭𝐢𝐜 𝐂𝐞𝐥𝐥 𝐌𝐞𝐦𝐨𝐫𝐲 (𝐄𝐩𝐢𝐂) is hiring 6 PhDs & postdocs! This is an amazing chance to be part of a top-tier research environment in Europe. I can’t recommend these labs enough! 🔬✨📢 Apply here 👇 & spread the word! #Hiring #AcademicJobs
- 🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
- I'm thrilled that this chapter from my PhD, completed and elevated by @sophievdhorst.bsky.social and other co-authors, is now published in Nature Communications! Check it out 👇.
- We present Repli-ID, an approach to identify proteins affecting DNA replication. Lge1 and Rox1 are new regulators of this process. Great work by @sophievdhorst.bsky.social, @lleonie.bsky.social and co-authors in collaboration with @andreichabes.bsky.social. tinyurl.com/mvvcp3xe
- Reposted by Leonie KollenstartExciting news!🌟 Together with Alexander van Oudenaarden, @jervdberg.bsky.social and @lleonie.bsky.social, we’ve been awarded a €2M NNF Synergy grant. We're thrilled to collaborate🤝 and to develop cutting-edge single-cell and single-molecule methods for replication and chromatin research! 🚀
- How reliably is the epigenome passed from one cell to its daughter cells? Alexander van Oudenaarden @jervdberg.bsky.social @grothlab.bsky.social @lleonie.bsky.social received @novo-nordisk.bsky.social grant to study this question ➡️new strategies to prevent disease & combat aging tinyurl.com/yh925b9u
- Reposted by Leonie KollenstartHow reliably is the epigenome passed from one cell to its daughter cells? Alexander van Oudenaarden @jervdberg.bsky.social @grothlab.bsky.social @lleonie.bsky.social received @novo-nordisk.bsky.social grant to study this question ➡️new strategies to prevent disease & combat aging tinyurl.com/yh925b9u
- Yesss! 🎉 We’ve secured a €2M Synergy grant from @novo-nordisk.bsky.social 🤯! What started as fun chats with my amazing friend @jervdberg.bsky.social, turned into an epic collaborative project 🤩. Huge thanks to Alexander and @grothlab.bsky.social for support and guidance. Can’t wait to dive in! 🚀
- How reliably is the epigenome passed from one cell to its daughter cells? Alexander van Oudenaarden @jervdberg.bsky.social @grothlab.bsky.social @lleonie.bsky.social received @novo-nordisk.bsky.social grant to study this question ➡️new strategies to prevent disease & combat aging tinyurl.com/yh925b9u
