Höfer Lab
The Höfer lab studies the epitranscriptomic mechanisms of gene regulation based on NAD-capped RNAs in bacteria and bacteriophages. We are located at the Max Planck Institute for terrestrial Microbiology, Marburg, Germany and area Member of SYNMIKRO
- Reposted by Höfer LabThis shows that "abortive infection" phenotypes are not neccessarily in all cases a "last line" of defense, but may be the consequence of mechanisms interferring with early steps in the phage life cycle. We further show synergy of daunorubicin with RM systems targeting the FST region T5 phages.
- 👇 - #phage
- 🔬 We're back! Kicking off 2026 with the 23. Industry Academia Panel: 📅 Jan 15, 2026, 4:00 PM CET 💻 Online via Zoom 🦠 Topic "New class of bacteriophage-based antibacterial solutions" Register: t1p.de/rqk1z Looking forward to seeing you there! 🎉 #Microbiology #PhageTherapy #VAAM #AMR
- Reposted by Höfer Lab🚨We are looking for a coordinator located at @uni-wuerzburg.de for our new excellence cluster NUCLEATE - Cluster of Nucleic Acid Sciences and Technologies 👇 www.uni-wuerzburg.de/fileadmin/03... Deadline: Jan 31 st, 2026
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- Reposted by Höfer LabPlease RT: We have an opening for a junior group leader position in „Phage Biology & Biotechnology“. www.fz-juelich.de/de/karriere/... Interested candidates are encouraged to contact me via email for further details. @spp2330.bsky.social; @mibinet.bsky.social
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- Reposted by Höfer LabLac de Louvie (2213 m elevation) was an incredibly stunning place to sample for microbes! Many thanks to altis.swiss for letting us use their maintenance cable car :) #CAPSOLUTION @mpimarinemicrobio.bsky.social @erc.europa.eu @hoeferlab.bsky.social @maxemilschon.bsky.social
- Reposted by Höfer LabSwitzerland welcomed us with summer weather and beautiful mountains! We started with the Lac de Champex (1467 m) which is influenced by human activity, and then hiked up to the Lacs de Fenêtre (2465 m) the next day. #CAPSOLUTION @mpimarinemicrobio.bsky.social @erc.europa.eu @hoeferlab.bsky.social
- Reposted by Höfer LabWe are looking to recruit a tenure track group leader in the field of Chemical/Synthetic Biology (in the broadest sense) to lead a research program within the Division of Protein & Nucleic Acid Chemistry ( www.jobs.ac.uk/job/DNW809/r... ) at the MRC Laboratory of Molecular Biology (LMB).
- Reposted by Höfer LabApplications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. 🔗 All positions: ki.se/en/about-ki/...
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- Reposted by Höfer Lab🔛LOEWE-RobuCop ist online, auch bei proloewe.de !🎯 Ziel von RobuCop @unimarburg.bsky.social ist es, die natürlich Mechanismen d. CO2-Fixierung, Stressantwort-+Resilienz-Mechanismen im Chloroplasten grundleg. zu🔬untersuchen, um robuste Photosynthese zu ermöglichen. ➡️ proloewe.de/de/loewe-vor...
- Reposted by Höfer LabWhat do you call a group of nucleic acid chemists? Suggestions welcome 🧬❤️ #SCNAC2025 @cjserpell.bsky.social @hoeferlab.bsky.social @boekhovenlab.bsky.social @rentmeisterlab.bsky.social @kgoepfrich.bsky.social @chlab.bsky.social
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- Reposted by Höfer LabManufacturing CAR T cells in the laboratory is expensive and time-consuming. An in vivo approach could get this powerful therapy to more people go.nature.com/45w5A5w
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- Reposted by Höfer LabWhat a lovely time at @synmikro.bsky.social! PIs, PhD students, PostDocs and associated members of RobuCop met at the kick off meeting to share ideas, discuss projects and connect with each other🌱🫰 Can't wait for our next meeting! Thank you @ramona-zuelch.bsky.social for the picture.
- Reposted by Höfer LabA new preprint from the lab in collaboration with Feng Jiang. www.biorxiv.org/content/10.1... This is a thread for you if you're interested in secretion systems, phages, and evolution. The extracellular contractile injection system (eCIS) is a mysterious microbial toxin delivery system.
- Reposted by Höfer LabExcited to announce the Molecular Biology of Archaea (MBoA) 2026! Join us in Cambridge, UK, from 6–10 July 2026 for the only international meeting dedicated to Archaea.
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- Reposted by Höfer LabIf you want to do single-cell RNA-seq on your favourite bacterium, here‘s our detailed Nature Protocol for microbial MATQ-seq. It profiles up to 600 genes in a single bacterial cell! www.nature.com/articles/s41...
- Reposted by Höfer LabAnd here it is, the completed BASEL collection finally published as early access in @plosbiology.org - see the thread for more details. 🤗🧬🎣
- Reposted by Höfer LabUnser #GirlsDay am MPI-TM war ein unvergesslicher Tag! Wir haben tolle Mädchen kennengelernt, die sich für #Mikrobenforschung begeistern. Vielen Dank an unsere Gäste: Wir freuen uns auf Euch als zukünftige Forscherinnen! #GirlsDay #GirlsInScience #GirlsRockScience
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- Reposted by Höfer LabAt LOEWE-Tree-M,👩🏽🔬👨🏻🔬scientists are studying the relationship between the #environment + #bacterial leaf #microbiome of #oaks.🌳The aim is to🔬analyze composition + activities to understand the influence on the leaf as habitat + food source. The knowledge gained will be used to strengthen the #forests.
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- Reposted by Höfer LabIn the latest from @kgoepfrich.bsky.social’s group, led by the relentless @tranmai.bsky.social, we expressed RNA origami “cytoskeletons” in vesicles! We were fascinated that small changes in design led to divergent results. Future potential for directed evolution?! 🧬🧪 www.nature.com/articles/s41...
- Reposted by Höfer Lab@science.org Cryo-EM reveals mechanisms of natural RNA multivalency | Science www.science.org/doi/10.1126/... #RNAsky #RNAbiology #Cryo-EM
- Huge congratulations to our #Phagebuster Nadiia for winning this year's #MarBinaMarburg Prize for Biotechnology and Nanotechnology! We are so entirely proud! Her work was also part of the @dfg.de funded SPP 2330 programm @spp2330.bsky.social @pozhydaieva.bsky.social #proudPI
- Congratulations to 𝗗𝗿. 𝗡𝗮𝗱𝗶𝗶𝗮 𝗣𝗼𝘇𝗵𝘆𝗱𝗮𝗶𝗲𝘃𝗮-𝗪𝗲𝗯𝗲𝗿 on being awarded the #MarBiNa Marburg Prize for Biotechnology and Nanotechnology 2024 for her groundbreaking research @hoeferlab.bsky.social on #bacteriophages! Go Nadiia! Exciting times ahead 🔬 🌟 s.gwdg.de/IYQH7M
- Reposted by Höfer LabSusan Gottesman and Gisela Storz, pioneers in regulatory RNA research, reflect on their personal scientific journeys and the evolution of their groundbreaking group research in two compelling articles. Gigi: www.sciencedirect.com/science/arti... Susan: www.sciencedirect.com/science/arti... #RNA
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- Reposted by Höfer LabHappy #InternationalWomensDay! As we celebrate the achievements of women everywhere today, a special shoutout to all women in science from us - from the trailblazers & changemakers to today’s innovators shaping the future. Thank you for your curiosity, courage & for redefining what’s possible! 🤗🔬💜
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- Reposted by Höfer LabFriends! The science that we love is under threat. World-wide, there're forces seeking to make it corporate-like, focused on deliverables, or even the enemy of society. Take a stand & celebrate science & music! #theconferencetoendallconferences - Registration starts NOW! woodstock.img.cas.cz
- IT'S HAPPENING! The Woodstock of Biology 2.0 meets Night Science @nightsciencepod.bsky.social 10-13 of June in Prague & the Woods of Bohemia... Be there or be REJECTED. #theconferencetoendallconferences
- Reposted by Höfer LabFor all of you who cannot access pubmed, here is a good alternative: europepmc.org
- Reposted by Höfer Labwe recently found some really neat RNA-guided DNA-cutting systems in phages. Despite remarkable similarities to CRISPR systems, including encoding guide RNAs in arrays, they appear entirely evolutionarily distinct (but definitely related to snoRNAs 🤓) We decided to call them TIGR-Tas systems 🐯
- Reposted by Höfer LabI'm excited to announce the 2025 Royal Society of Chemistry's Nucleic Acid Forum will take place on 11th July at Burlington House, London! Booking open's soon! @roysocchem.bsky.social @drzoewaller.bsky.social @diantoniogroup.bsky.social @yiliangding.bsky.social www.rsc.org/events/detai...
- Reposted by Höfer LabInvitation to our #Synmikro annual meeting in #Marburg, April 23rd, 2025 at the Cineplex Cinema: "Enzyme Design and Evolution - Unlocking a ustainable Future". Please register: www.eventbrite.de/e/enzyme-des... Participation is free
