Eduardo Eyras
Director of the Shine-Dalgarno Centre for RNA Innovation
EMBL Australia Group Leader
Australian National University
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- Excited to share our latest preprint: "SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications" www.biorxiv.org/content/10.6... Led by Stefan Prodic #RNA #Epitranscriptomics #Nanopore 1/6
- SWARM is an AI framework for nanopore direct RNA sequencing that detects m6A, pseudouridine (Ψ), and m5C mods at single-nucleotide & single-molecule resolution. Key innovation: Crosstalk-aware training with non-target mods & validated cellular signals to reduce false positives. 2/6
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- Thrilled to announce that I've been appointed Director of the ANU Shine Dalgarno Centre for RNA Innovation. Honoured to work with a world-class team advancing RNA science. Stay tuned for more exciting updates 🚀 jcsmr.anu.edu.au/research/cen... #RNA #RNAInnovation #ANU
- Very sad to hear about Peer Bork's passing. I met him as a very junior group leader in an early European network on splicing. He's been an inspiration for me since then. He visited us in Canberra ~2 years ago for my EMBL-A review. His legacy lives on www.embl.org/news/embl-an...
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- SWARM: A Single-Molecule Workflow for High-Precision Profiling of RNA Modifications #RNAmods #epitranscriptomics #nanopore github.com/comprna/SWARM www.biorxiv.org/content/10.6...
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- BenchMake: turn any scientific data set into a reproducible benchmark iopscience.iop.org/article/10.1... by Amanda Barnard pypi.org/project/benc...
- Quantification of transcript isoforms at the single-cell level using SCALPEL nature.com/articles/s41... by @miriplass.bsky.social and her team
- Free online event about CSIRO Industry PhD (iPhD) program. You will also hear from current iPhD students who will share their experiences and advice events.csiro.au/Events/2025/...
- Reposted by Eduardo Eyras"a fascinating case study on the limits of AI in biology and the harms of current publishing incentives" rachel.fast.ai/posts/2025-0...
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- CSIRO Industry PhD position available in my group: Prediction of molecular interactions with RNA using AI research.csiro.au/iphd-opportu... #RNA #molecularinteractions #AI #academicjobs
- Boarding an infinitely long plane 😊
- Reposted by Eduardo EyrasPhage people: Rich Losick and I are combing the world looking for T4 rIIB mutant FC0 (also known as P13). FC0 was the starting point for Francis Crick's beautiful 1961 paper on the triplet nature of the genetic code. We want to sequence it. Anyone have it in an ancient stock collection?
- Don't miss AJ's talk (T-93) on dFORCE this afternoon in the RNA processing session (Ballroom A) #RNA2025 #RNA25
- "Single-molecule multimodal timing of in vivo mRNA synthesis" a collaboration with Rippei Hayashi's lab, work led by AJ Sethi #RNA #pre-mRNA #splicing #RNAprocessing #m6A #polyadenylation www.biorxiv.org/content/10.1...
- SWARM (Single-molecule Workflow for Analysing RNA Modifications) detects pseudouridine, m6A, and m5C on individual molecules from direct RNA nanopore signals (in both chemistries RNA002 and RNA004) github.com/comprna/SWARM see more on poster P2-396 at #rna2025 #RNA25 #RNAmods
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- "Bullying is a means for mediocre scientists to rise to the top" … often supported by allies and networks. www.nature.com/articles/s41...
- Still available: CSIRO industry PhD project - Prediction of molecular interactions with RNA using AI for basic research and therapeutic discovery - collaboration with CSIRO and RNAfold.ai science.anu.edu.au/study/resear...
- Reposted by Eduardo Eyras🧬 Meet Dr. Liana Lareau, 2025 MTI Innovator Awardee! Her lab is using CRISPR + machine learning to reprogram RNA and silence toxic genes - offering hope for retinitis pigmentosa & beyond. A new era of mutation-agnostic therapeutics. #MTI #CRISPR #RNA moleculartherapeutics.org/2025-mti-inn...
- CSIRO Industry PhD program: Prediction of molecular interactions with RNA using AI
- Reposted by Eduardo Eyras[Not loaded yet]
- "Single-molecule multimodal timing of in vivo mRNA synthesis" a collaboration with Rippei Hayashi's lab, work led by AJ Sethi #RNA #pre-mRNA #splicing #RNAprocessing #m6A #polyadenylation www.biorxiv.org/content/10.1...
- We introduce dFORCE (direct fractionated observation of RNA coupled to elongation), a single-molecule approach capturing endogenous pre-mRNA processing without metabolic labelling or amplification. dFORCE separates elongating pre-mRNA from post-transcriptional pre-mRNA and catalytic intermediates
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- Amazing opportunity: Lecturer / Senior Lecturer in Machine Learning in Omics at Melbourne Integrative Genomics and the School of Mathematics and Statistics, University of Melbourne, Australia. jobs.unimelb.edu.au/en/job/91945...
- PhD opportunities in Computational Biology in fantastic labs!
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- Reposted by Eduardo EyrasPostdoc positions on nuclear RNA biology available in the Heick Jensen lab. Come join us in tiny Denmark. Interested? - then follow this link: mbg.au.dk/aktuelt/ledi...
- ModiDeC: a multi-RNA modification classifier for direct nanopore sequencing www.biorxiv.org/content/10.1...
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- Great way to end the year with some bowling. I feel really lucky to have such a fantastic research group! github.com/comprna/ jcsmr.anu.edu.au/research/gro...
- Our technology platforms team is looking for a Senior Technical Officer responsible for broad-ranging long-read sequencing services and protocol optimisations for ONT and PacBio platforms jobs.anu.edu.au/jobs/senior-... @jcsmr.bsky.social
- EMBL Australia invites expressions of interest for Scientific Head role www.emblaustralia.org/eoi-embl-aus...
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- Fantastic Dagstuhl Seminar last week on Deep Learning and RNA - 5 days of exciting science discussions. It was great to meet again with friends and collaborators www.dagstuhl.de/en/seminars/... #RNA #AI #ML
- Mis-splicing of a neuronal microexon promotes CPEB4 aggregation in ASD www.nature.com/articles/s41...
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- We have an opening for an industry PhD position (CSIRO iPhD Program) to work with CSIRO and RNAfold.ai on "Prediction of molecular interactions with RNA using AI for basic research and therapeutic discovery". More info and eligibility requirements here: science.anu.edu.au/study/resear...
- Reposted by Eduardo Eyras[Not loaded yet]
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- Two positions open to work with us at the National Therapeutic mRNA Platform (NTRP) within the ANU Shine-Dalgarno Centre for RNA Innovation (SDCRI) - contribute to RNA Science and its applications @ourANU @JCSMR #SDCRI #RNA #mRNA jobs.anu.edu.au/jobs/team-le...
