Khaled_Selim Lab
Microbiology | Cell Signaling | Structural Biology | Institute of Phototrophic Microbiology @hhu.de
phototrophic-microbiology.hhu.de/en/
Central Metabolism Coordination by #PII & #cdiAMP & #cdiGMP & #Ca2+ signaling #Cyanobacteria
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- Reposted by Khaled_Selim LabHappy to announce that our review article on vesicle-coupled mRNA trafficking is now availalbe @mibinet.bsky.social #EMBOrnaLocalization link.springer.com/article/10.1...
- Reposted by Khaled_Selim LabOur new paper, out today! We resurrected ancient nitrogenases first used by life on Earth 3 billion years ago. We combined synthetic biology and geology & validated their chemical #biosignature in rocks that helps reveal ancient life on Earth!(and beyond!) Link: www.nature.com/articles/s41...
- Reposted by Khaled_Selim LabResearchers led by Jun.-Prof. Dr. Julie Zedler at #UniJena have developed a sustainable alternative to synthetic food colourings: they have modified cyanobacteria so that they produce yellow natural colourings from light and carbon dioxide alone. ➡️ www.uni-jena.de/en/386595/gel…
- Reposted by Khaled_Selim LabA prophage-encoded abortive infection protein preserves host and prophage spread www.nature.com/articles/s41...
- Reposted by Khaled_Selim LabFormation & function of #MembranelessOrganelles! #CryoET structures of #proteasome storage granules inside cells! Read our paper @cp-cell.bsky.social! ❕Publication: doi.org/10.1016/j.ce... ❕Press Release: www.biochem.mpg.de/en/pressroom @uoftmedicine.bsky.social @erc.europa.eu #UPSmeetMet
- Reposted by Khaled_Selim LabWe are looking for new editors for Microbiology, the flagship journal of @microbiologysociety.org Deadline for applications is 16 Feb 2026 microbiologysociety.org/who-we-are/j...
- Reposted by Khaled_Selim LabNew AI tool “Helixer” identifies genes in newly sequenced organisms. Helixer identifies genes directly from DNA sequences. Developed by team around @usadellab.bsky.social @fz-juelich.de, @apmweber.bsky.social , @sebtriesch.bsky.social @hhu.de et al. www.fz-juelich.de/en/news/arch...
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- Reposted by Khaled_Selim LabWE ARE #HIRING: [reposting=👌 🙏 ] 2 funded positions for #nanopore related projects @unibas.ch 🇨🇭: 1️⃣ #PhD Candidate in Single-Molecule Biophysics using Nanopore Trapping. 2️⃣ #PhD Candidate in Microplastic Detection Using Micropores and Microfluidics. More info: schmid.chemie.unibas.ch/en/join-us-1/
- Reposted by Khaled_Selim LabHow did eukaryotic cells with complex architecture evolve from simpler prokaryotic cells? DNA analyses offer possible answers @nature.com www.nature.com/articles/d41... www.nature.com/articles/s41... @bristoluni.bsky.social www.nature.com/articles/s41... www.nature.com/articles/s41...
- www.ufz.de/index.php?en... Here ist a small press about our recent findings about Guanidin metabolism in #cyanobacteria Toxicity vs. Uptake & Catabolism A great collaboration between @ufz.de & @hhu.de & @unihalle.bsky.social HERE is the original publication @pnas.org www.pnas.org/doi/10.1073/...
- Our latest paper on Guanidine metabolism in #Cyanobacteria is out @pnas.org (it's useful as N nutrient but toxic at the same time) A great collaboration w Klähn lab w small part from us on toxicity😅 @hhu.de @spp2389.bsky.social @sfb1381.bsky.social @mibinet.bsky.social www.pnas.org/doi/10.1073/...
- New enzyme with dual function as methionine synthase and a glycine betaine methyltransferase Methionine synthesis and glycine betaine demethylation are intricately intertwined in cosmopolitan marine bacteria www.pnas.org/doi/full/10....
- Reposted by Khaled_Selim LabWe Are very happy that our Paper was published. Thank to everyone involved pubs.acs.org/doi/10.1021/... @mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social
- Reposted by Khaled_Selim LabHappy to share our recent preprint: "DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity" www.biorxiv.org/content/10.6... @spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social
- Reposted by Khaled_Selim LabAncestral sequence reconstruction reveals CTP-dependent loading of the bacterial centromere-binding protein ParB as an ancient evolutionary feature Now published: tinyurl.com/4ddhwbb3 Thanks to the Hochberg and Bange labs for the great collaboration!
- Reposted by Khaled_Selim LabWe are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...
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- Reposted by Khaled_Selim LabRegistration is open for the 2026 Gordon Research Conference on Microbial Stress Response to be held on July 19-24 2026!! Submit your abstract by February 15th to be considered for a short talk. Apply now before it fills up!! Hope to see you there!! www.grc.org/microbial-st...
- Reposted by Khaled_Selim LabNew manuscript alert. Turns out that calcium ion coordination may be a more common mechanism than we initially expected to trigger polymerization of extracellular filaments. @mikesleutel.bsky.social @vikramalva.bsky.social www.biorxiv.org/content/10.6...
- Reposted by Khaled_Selim LabMedina, Chang et al. of the @nanigrotjahn.bsky.social lab introduce a new method based on the Surface Morphometrics pipeline to measure global and local thicknesses of organellar #membranes from cellular cryo-electron tomography data. rupress.org/jcb/article/... #CryoET
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- Reposted by Khaled_Selim LabA new year brings new opportunities: we are looking to fill a permanent professorship position with a Microbiologist preferably with expertise on archaeal biology, RNA biology or imaging techniques to unravel cell biology in prokaryotes! Please share and/or apply :)! www.nature.com/naturecareer...
- Reposted by Khaled_Selim LabWe are starting 2026 by looking for candidates to apply for the Junta de Andalucía PhD fellowship. If you are interested in bacterial secretion systems and molecular biology, get in touch. More info about our work: personal.us.es/pbguzman/ & regarding the call www.investigacion.us.es/convocatoria...
- Reposted by Khaled_Selim LabA balance of infection and harmony called endosymbiosis helps shape evolution. For the first time, biologists have reproduced this arrangement between microbes in a lab.
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- Reposted by Khaled_Selim LabCongratulations to Doi Basu @dwaipayanbasu.bsky.social for publishing his first first-author paper from the lab! The cryoEM structure of a tubulin-like protein from bacteriophage Goslar forms "microtubules" with nine protofilaments! authors.elsevier.com/a/1mM253SNvc...
- Reposted by Khaled_Selim LabA free, open-access library of high-quality organism illustrations for science communication
- Reposted by Khaled_Selim LabThanks to all who provide these illustrations for free - it helps so much for teaching etc! It’s like a Christmas present again and again ☺️
- Reposted by Khaled_Selim LabOld and mighty: A novel cytosine nucleobase modification in phage genomic DNA renders the majority of restriction-based host defence systems useless. Great collaboration with the Bielefeld Gang. | Applied and Environmental Microbiology journals.asm.org/doi/10.1128/...
- Reposted by Khaled_Selim LabTiffany Zarrella et al. provide new insights into the role of the bacterial second messenger cyclic di-adenosine monophosphate (c-di-AMP) in maintaining cell envelope homeostasis in Streptococcus pneumoniae. #MicroSky #cyclic-di-AMP onlinelibrary.wiley.com/doi/10.1111/...
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- Reposted by Khaled_Selim LabWhen I quit Twitter/X, I made sure to delete 18 years of Tweets, because I knew this was coming. If you’re still on that platform, you are enabling sooooo much disinformation.
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- Reposted by Khaled_Selim LabWe are looking for a team leader to join the cryo-EM facility work at the new Ernst Ruska-Centre 2.0 at the Forschungszentrum Jülich. We have a series of microscopes used by (@irene-vercellino.bsky.social, Schröder, @sachsegroup.bsky.social) and external users. www.fz-juelich.de/de/karriere/...
- The beauty of the art! 😍 www.sciencedirect.com/science/arti...
- Final version is out! Our large-scale cryo-ET dataset 🔬 of Chlamydomonas reinhardtii 🦠 is now published in @cp-molcell.bsky.social Huge collaborative effort! So glad to see the community already using it to develop new resources & tools. Check it out here: shorturl.at/z4i4c #CryoEM #CryoET
- Reposted by Khaled_Selim LabTake advantage of this fantastic opportunity to become part of the SCALE community! Several professorships and group leader positions are available at Goethe University and FIAS. We are looking for professors in the fields of molecular microbiology, cellular biochemistry, and molecular biochemistry.
- ⏰Call for Applications - Join Our Team and Help Shape Our Cluster @goetheuni.bsky.social and the Cluster of Excellence SCALE - Subcellular Architecture of Life are seeking 3 highly motivated scientists to join a vibrant and innovative research community on Campus Riedberg. Share with your network!
- New function for PII-like protein, PstA, in bacterial death.... Cyclic di-AMP inhibits Listeria monocytogenes thymineless death during infection journals.asm.org/doi/10.1128/...
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- Reposted by Khaled_Selim LabHow do simple cells make complex patterns? We discovered a key piece in cyanobacteria—an ancient enzyme repurposed to activate a pattern-forming signal. A conserved signaling strategy, showing how nature reuses tools to build multicellularity. www.cell.com/iscience/ful...
- Reposted by Khaled_Selim LabVery happy to See This Published!!!! Thanks for the collaboration link.springer.com/article/10.1...
- Reposted by Khaled_Selim LabAttention scientists from all over the world🙃 The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪 Get your international & interdisciplinary team. It's time to put your bold research idea into practice! 🔗https://bit.ly/48VsGCG 📅 15 Dec 2025–26 Mar 2026 #sts #LifeSciences
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- Reposted by Khaled_Selim LabHappy to share that our work on HLp, a bacterial histone from Leptospira perolatii, is now published in Nature Communications 🎉 In this study, we show that HLp forms stable tetramers that wrap ~60 bp of DNA, revealing a distinct histone–DNA organization in bacteria. www.nature.com/articles/s41...
- Reposted by Khaled_Selim Lab📣Interested in doing your PhD in Plant Sciences 🌱, Microbial Sciences 🦠 or Computational Biology 👩💻? @ceplas.bsky.social offers 10 fully funded PhD 🎓fellowships. Pls repost and forward to interested candidates holding BSc degree.
- ‼️Please RT: The CEPLAS Graduate School call for 2026 is now open! Detailed info on our website: bit.ly/4q19JWk @hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
- This week in @science.org Structural insight into the incorporation of far-red chlorophyll f in cyanobacterial photosystem I www.science.org/doi/10.1126/... #cyanobacteria #plantscience
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- IsoNet2 determines cellular structures at submolecular resolution without averaging biorxiv.org/content/10.64898/20…
- More than well deserved Mark! I'm so happy for you!
- Reposted by Khaled_Selim LabWe are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
- Reposted by Khaled_Selim LabConfused by all the histones that are cropping up in organisms that are decidedly NOT eukaryotes? check out our review - fantastic work by team NucEvo in the #Lugerlab The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms - www.annualreviews.org/content/jour...
- Reposted by Khaled_Selim Lab‼️Please RT: The CEPLAS Graduate School call for 2026 is now open! Detailed info on our website: bit.ly/4q19JWk @hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
- Come and join us at @ceplas.bsky.social for a structured #PhD program A new call for PhD students
- Reposted by Khaled_Selim LabNew call for PhD students to join CEPLAS
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- Our latest paper on Guanidine metabolism in #Cyanobacteria is out @pnas.org (it's useful as N nutrient but toxic at the same time) A great collaboration w Klähn lab w small part from us on toxicity😅 @hhu.de @spp2389.bsky.social @sfb1381.bsky.social @mibinet.bsky.social www.pnas.org/doi/10.1073/...
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