Robert Krautz
Assistant Professor at University of Copenhagen | Gene Regulation | Developmental Biology | Method Development | http://tgrlab.org
- Reposted by Robert KrautzEvery American needs to watch this:
- Reposted by Robert KrautzAuschwitz was at the end of a process. We must remember that it did not start from gas chambers. This hatred gradually developed: from ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder. Auschwitz took time.
- Reposted by Robert KrautzCongratulations to @groth-anja.bsky.social on receiving the Novo Nordisk Foundation Jacobæus Prize 🏆 we’re proud to see Anja's mentorship, leadership, & pioneering work in epigenetic cell memory getting top recognition 👏 celebrating the contributions of past & present lab members to this work too 🥳
- Reposted by Robert KrautzOur work on improving human egg quality was featured in @theguardian.com. We hope this will help to make #IVF more successful and allow more couples to conceive. 💜
- Reposted by Robert KrautzI'm guest-editing a collection on "Enhancer-promoter interactions" at Genome Biology. Please send us your exciting stories! link.springer.com/collections/...
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- Reposted by Robert KrautzBizarre that our 2020 #Drosophila #AMP review already feels out of date. Thanks to #AnnualReviews to cover the many updates in the field and present a much more complete picture of the diversity, mechanisms, topics, of fly immunity re: host defence peptides. www.annualreviews.org/content/jour...
- Reposted by Robert KrautzWe (@sobuelow.bsky.social) developed AF-CALVADOS to integrate AlphaFold and CALVADOS to simulate flexible multidomain proteins at scale See preprint for: — Ensembles of >12000 full-length human proteins — Analysis of IDRs in >1500 TFs 📜 doi.org/10.1101/2025... 💾 github.com/KULL-Centre/...
- AF-CALVADOS: AlphaFold-guided simulations of multi-domain proteins at the proteome level biorxiv.org/content/10.1101/202…
- Reposted by Robert KrautzOur collab w. V Goel, @nicholas-aboreden.bsky.social , J Jusuf, G Blobel, L Mirny, @irate-physicist.bsky.social out in @natsmb.nature.com www.nature.com/articles/s41... Was co-submitted with @allanaschooley.bsky.social @jobdekker.bsky.social whose paper should also come out soon Brief thread 👇
- been lurking here a while but time to spend less time in the bad place Here's my latest work in collab w/ Viraat Goel, @andersshansen.bsky.social, Leonid Mirny, Nick Aboreden, Gerd Blobel et al. Dynamics of microcompartment formation at the mitosis-to-G1 transition www.biorxiv.org/content/10.1...
- Reposted by Robert Krautz“Harvard geneticist David Reich said … increasingly sophisticated analysis of genetic material made possible by technological advances shows that virtually everyone came from somewhere else, and everyone’s genetic background shows a mix from different waves of migration that washed over the globe.”
- Reposted by Robert KrautzGenes are not On/Off switches. In a new preprint we show that HDAC3 is key to establish correct transcriptional dose in development. Gr8 work from N. Stamidis @ucph.bsky.social and collab. @jamiehackett.bsky.social @gregersenlab.bsky.social . Huge thx to all authors! www.biorxiv.org/content/10.1...
- Guess, I'll have a coffee then.
- Reposted by Robert KrautzExcited to share our Review on human PGC development covering the latest in vivo observations & in vitro developments, esp. in the last 5 years. Have a read! journals.biologists.com/dev/article/... From: @astar-gis.bsky.social @ki.se Warwick University, @gurdoninstitute.bsky.social
- “Nurses should be at the very top of our social hierarchy but we live in a world where it’s just the opposite,” www.theguardian.com/film/2025/ju...
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- Reposted by Robert Krautz📢 We are recruiting! Several projects are available and can be tailored to the candidate's profile. Most include confocal imaging/spatial OMICs technologies. Please share and RT 🙏
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- Reposted by Robert KrautzCalling all aspiring Postdocs! One extra week to apply to join our exciting HFSP-funded project to uncover how chromatin moves to function. Deadline July 15th. www.mdc-berlin.de/career/jobs/...
- Postdoc🚨! Come join our HFSP team to uncover how chromatin moves in cells and what this means for genome function! Great opportunity to combine single-cell genomics, live imaging and polymer physics in the unique mammalian retina with @andersshansen.bsky.social, Davide Michieletto & Sandra Tenreiro
- Reposted by Robert KrautzWe have created a new DNase I- & ATAC-seq peak caller that uses an adaptive background model that controls for copy number variation & aneuploidy. It performs a per-nucleotide test (+FDR correction) and is very fast. Please try it out and give us feedback! github.com/vierstralab/...
- Reposted by Robert KrautzOur paper describing the Range Extender element which is required and sufficient for long-range enhancer activation at the Shh locus is now available at @nature.com. Congrats to @gracebower.bsky.social who led the study. Below is a brief summary of the main findings www.nature.com/articles/s41... 1/
- Reposted by Robert Krautz(1/n) Excited to present the latest work from the de Wit lab, where we identify and characterise loop extrusion-mediated fountains in mammalian genomes using acute depletion of 3D genome regulators: doi.org/10.1093/nar/.... A Bluetorial🧵:
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- Reposted by Robert KrautzLatest from the lab! Led by @xuening-he.bsky.social, establishing a framework for interpretation of the motif syntax of regulatory elements and a quantitative model for transcription factor cooperativity. Plenty of cool stuff revealed, including TF redundancy and synergy, and their regulatory roles!
- Reposted by Robert KrautzPostdoc🚨! Come join our HFSP team to uncover how chromatin moves in cells and what this means for genome function! Great opportunity to combine single-cell genomics, live imaging and polymer physics in the unique mammalian retina with @andersshansen.bsky.social, Davide Michieletto & Sandra Tenreiro
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- Reposted by Robert KrautzExcited to unveil Boltz-2, our new model capable not only of predicting structures but also binding affinities! Boltz-2 is the first AI model to approach the performance of FEP simulations while being more than 1000x faster! All open-sourced under MIT license! A thread… 🤗🚀
- Reposted by Robert KrautzA three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @camplantsci.bsky.social www.jobs.cam.ac.uk/job/51488/
- Reposted by Robert KrautzHow does metabolism act through generic chromatin modifiers promote specific cellular states? Simultaneous modification of transcription factors and chromatin, enhancing epigenetic signal to noise ratios. www.embopress.org/doi/full/10....
- Reposted by Robert KrautzNew preprint! We have discovered that the splicing factor Sex lethal (Sxl - well known for its role in sex determination) binds to chromatin and regulates tRNA synthesis in neurons by interacting with RNA Pol III! Highlighting Sxl as a novel modulator of neuronal homeostasis. tinyurl.com/s44s2z95
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- Reposted by Robert KrautzFunded PhD Studentship available in my lab at @lsiexeter.bsky.social. Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply! lsi.exeter.ac.uk/groups/hendr...
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- Reposted by Robert Krautz12. Like art, music, philosophy, and literature, science is literally part of humanity's heritage. My colleagues and I have had the amazing opportunity to be part of something vastly larger than ourselves, with meaning that transcends any state, regime, or generation. They can't take that away.
- Important reminder by @vivienm.bsky.social that actively shaping the context in laboratories makes a difference for how included, represented and balanced researchers feel. Apart from being the right way of treating others, respect directly improves productivity, too. www.nature.com/articles/s41...
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- We are hiring.🚨 The Tissue Gene Regulation Lab is looking for an experimental PhD student or PostDoc to join our efforts in devising new single cell methods and decoding gene regulation. 💻🔬🧫 Come join me and my lab in beautiful Copenhagen. 🇩🇰 PhD - lnkd.in/dtKz_gnA PostDoc - lnkd.in/dBgn6AcK
- If you 🫵: • want to understand how gene regulatory mechanisms instruct the development of tissues 🫀 🧠 🫁 • want to live in a country with a stabil & sane government 🧑⚖️ • want to work in a stimulating, stress-free lab 🧘♀️ • burn for single cell methodology and gene regulation 💣 You should apply! 📝
- We have a new website. The Tissue Gene Regulation Lab can now be found at tgrlab.org. 🫀 🧬 More information and updates will be added continuously.
- Reposted by Robert KrautzJoin us for this exciting @embo.org workshop to explore recent advances in our understanding of enhancer mechanisms and the critical roles of enhancers in human health! 🧬 🧪 Submit an abstract by March 17 to be considered for short talk. Register by April 1 to participate! 😊 @sdu.dk @dg.dk
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- Reposted by Robert KrautzPhD position vacant in the lab. Please spread the news. Study topic: Mammalian nuclear RNA production and turnover systems. Learn more about the lab here: www.mRNP.au.dk
- All European Academies (ALLEA) statement on threats to academia: "These new restrictions also threaten the careers of [..] professionals, and may cause lasting harm to the fundamental research [..], as well as efforts to secure a healthy, just, and safe world for all." allea.org/wp-content/u...
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- Great summary from Ayako Suzuki on the impact FANTOM and FLJ had on genome annotation and protein inference before reference genomes 🧬 even existed. Full length cDNAs, cap and oligo trapping 🪤 were leading the way! www.nature.com/articles/s41...
- Reposted by Robert KrautzInterested in exploring epigenetic cell memory? Join us!! 6 PhD and postdoc positions available in our new center, EpiC.
- 🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
- Reposted by Robert Krautz🚨𝐌𝐚𝐣𝐨𝐫 𝐉𝐨𝐛 𝐀𝐥𝐞𝐫𝐭!🚨The Groth @groth-anja.bsky.social, Mailand, Nilsson @nilssonlab.bsky.social & Krietenstein @nilskrietenstein.bsky.social labs are hiring 𝟔 𝐏𝐡𝐃&𝐩𝐨𝐬𝐭𝐝𝐨𝐜𝐬 to join the new Center for Epigenetic Cell Memory (EpiC) in Copenhagen, Denmark. Apply here: tinyurl.com/yvd93na2 & please share!
- Reposted by Robert KrautzPostdoc positions on nuclear RNA biology available in the Heick Jensen lab. Come join us in tiny Denmark. Interested? - then follow this link: mbg.au.dk/aktuelt/ledi...
- Job alert.🚨 Come join us in beautiful Copenhagen 🇩🇰 to develop computational tools to decode gene regulatory mechanisms from single cell data.💻🔬🧫 @randersson.bsky.social will be hiring either a PhD or a PostDoc. There is no supervisor I could recommend more! tinyurl.com/3v4uvmz4 tinyurl.com/yc83enfa
- If you 🫵: • want to understand how, when and where genetic variants 🧬 disrupt normal development and lead to disease 🫀 • want to live in a country with a sane government 🧑⚖️ • want to work in a stimulating, stress-free lab 🧘♀️ • burn for gene regulation 💣 You should apply! 📝
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- Reposted by Robert KrautzI’ve unfortunately needed to add more material to my post from yesterday. The re-election of Donald Trump is looking like the biggest act of American self-destruction since the Civil War. Same link, new title and some updates.
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- Reposted by Robert KrautzOur new paper is finally out, showing that the same enhancer sequences - and likely the same transcription factors recruited to them - affect the activity of distal enhancers and their looping over to target gene promoters. www.nature.com/articles/s41...
- Reposted by Robert KrautzAuschwitz was at the end of a long process. It did not start from gas chambers. This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder. Auschwitz took time.
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- Reposted by Robert KrautzWe are hiring! 3-year BBSRC-funded postdoc position available. TEs, epigenetics, pregnancy: if you love one or more of these keywords, apply through the link below. Please spread the word.
- Reposted by Robert Krautz📣 Registration for the next Non-Coding Genome course at @institutcurie.bsky.social closes on February 15th! Don't miss this opportunity to explore the versatility of non-genic DNA elements and non-coding RNAs with internationally renowned experts. ▶️ training.institut-curie.org/courses/non-...
