Miguel Gómez-Raya
Postdoc in the Cell Biology and Virology of Archaea Unit @pasteur.fr
Archaea is the coolest domain of life! 🔬🦠
PPU PhD @pasteur.fr, Mart Krupovic
MSc Microbiology @helsinki.fi, Mikael Skurnik
BSc Biomedicine @UB.edu
- Reposted by Miguel Gómez-RayaExtremophile alert! Registration is OPEN for the 2026 EMBO Archaeal workshop in Cambridge. Spaces are limited, so register soon with an abstract if you’d like to give a talk. If you can’t come in person, we are welcoming virtual attendees. So join us online where all talks will be screened!
- Sign up now for the EMBO Workshop "#MolecularBiology of #Archaea: Life Through the Prism of Archaea" in Cambridge, UK, 6–10 July 2026. Deadline: 15 April meetings.embo.org/event/26-archaea #EMBOArchaeaBiology #EMBOevents #CellBiology #StructuralBiology #ecology #evolution #biophysics 🧪
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- Reposted by Miguel Gómez-RayaBacteria chromosomes contain Genomic Islands that provide virulence, antibiotic resistance, MGE-defence,... They transfer between cells, but the mechanism of most remains elusive. Here we explore the conjugative capacity of these mysterious Genomic Islands. www.biorxiv.org/content/10.6...
- Reposted by Miguel Gómez-RayaUn poste de Maître de Conférence est ouvert pour rejoindre notre unité à Lyon ! Possibilité de rejoindre mon équipe pour travailler sur: - caractérisation des mécanismes de défense anti-phage - transfert horizontal et interactions entre éléments génétiques mobiles N'hésitez pas à me contacter
- 📢 Recrutement d’un(e) Maître(sses) de conférence en Biochimie générale, spécialité bactériologie moléculaire à MMSB 🔬Recherche *Immunité anti-phages *Réponse au stress, modulation de la croissance bactérienne ✉️ christophe.grangeasse@cnrs.fr 📚Enseignement : Université Lyon I ✉️ patrice.gouet@ibcp.fr
- Reposted by Miguel Gómez-RayaWe found a new mode by which bacteria deplete NAD+ to protect from phages. And then we found how phages overcome this defense Discovered by talented biochemist Dr Ilya Osterman, read the preprint: tinyurl.com/Narp-ap A thread 🧵
- Reposted by Miguel Gómez-RayaThe origin of eukaryotic cells continues to be one of the greatest mysteries in biology. EMBL Grenoble is excited to welcome Florian Wollweber, who will use cutting-edge imaging techniques to study Asgard archaea — microbes closely related to our earliest ancestors. 🦠🔬 www.embl.org/news/people-...
- Reposted by Miguel Gómez-RayaUsing micropatterning & thousands of hours on the microscope @manuelthery.bsky.social and the #CytoMorphoLab reimagined the Musée D’Orsay. Accompanied by an orchestra and poet, their images transported us into the cellular universe. I remembered why I am a cell biologist. All of this is in us. Wow!
- Reposted by Miguel Gómez-RayaA reminder to sign up for the 2026 EMBO archaeal meeting im Cambridge: meetings.embo.org/event/26-arc.... Registration is open. We are looking forward to hosting you!
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- Reposted by Miguel Gómez-Raya#NatMicroPicks Asgard archaea and the origin of eukaryotes! 🦠 Eukaryotic cellular complexity evolved largely within the Asgard lineage before mitochondrial endosymbiosis and later bacterial gene acquisitions #MicroSky www.nature.com/articles/s41...
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- Reposted by Miguel Gómez-RayaOrdering of cell cycle events by regulated proteolysis is not just for eukaryotes: @buzzbaum.bsky.social et al define mechanisms underlying switch-like degradation of archaeal ESCRT-III CvdB in Sulfolobus Thanks to @reviewcommons.org for another #RefereedPreprint link.springer.com/article/10.1...
- Reposted by Miguel Gómez-RayaTwo fantastic papers published back-to-back in @natmicrobiol.nature.com show that strictly lytic phages can persist intracellularly for long periods of time. Very much in line with ideas we had suggested in a recent study. Highly recommended reads 👇 www.nature.com/articles/s41...
- Reposted by Miguel Gómez-RayaProud of contributing to this work on archaeal chromosome segregation! Congrats, Rachel and Steve! www.nature.com/articles/s41...
- Reposted by Miguel Gómez-Raya@peterfineran.bsky.social and colleagues develop Tn-seq for phages by leveraging anti-CRISPR (Acr) as a positive selectable marker in the presence of CRISPR-Cas counter-selection, and identify essential genes in phage from non model orgs www.biorxiv.org/content/10.6...
- Reposted by Miguel Gómez-Raya1. As we recently joined BlueSky, we want to repost this story for all newcomers! We sat down with @radler92.bsky.social to get more insight into the unique videos from his recent preprint on Promethearchaeota (formerly Asgard archaea). doi.org/10.1101/2025... (Videos and info below)
- Reposted by Miguel Gómez-RayaAre you a long-time fan of Archaea, an extremophile-phile, or are you simply curious? Either way, we have good news. We’re delighted to announce the 2026 EMBO Workshop on Archaea, 6–10 July. Sign up: meetings.embo.org/event/26-arc... We look forward to seeing you in Cambridge, UK. Please repost!
- Reposted by Miguel Gómez-RayaCalling all archaeal enthusiasts! 🔬🔥 From molecular machines to microbial communities, Archaea never fail to surprise us! We are excited to announce the 2026 EMBO Workshop on the Molecular Biology of Archaea, 6–10 July in Cambridge, UK! Sign up here: meetings.embo.org/event/26-arc... #ArchaeaSky
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- Reposted by Miguel Gómez-RayaDelighted to share our new preprint: www.biorxiv.org/content/10.6... We address a longstanding question about the role of the topoisomerase reverse gyrase in hyperthermophiles. Great collaboration with Baranello and @tobiaswarnecke.bsky.social groups. #Archaeasky #Microsky
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- Reposted by Miguel Gómez-RayaOnline now: Discovery, characterization, and application of chromosomal integration sites in the hyperthermophilic archaeon Sulfolobus islandicus
- Reposted by Miguel Gómez-RayaAn Asgard Archaeon (Lokiarchaeum ossiferum) growing and retracting its arms
- Reposted by Miguel Gómez-RayaWrap up video from the Symbiotic Partners of Asgards Research Cruise (SPARC). youtu.be/mgmEh_qag5E?... #AsgardArchaea @schmidtocean.bsky.social @moorefound.bsky.social @texasscience.bsky.social @utmsi.bsky.social
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- Reposted by Miguel Gómez-RayaCheck out our latest paper on mirusviruses, one of the most remarkable new groups of protist viruses - extremely diverse, carry lots of spliceosomal introns (including new homing introns) and are at the evolutionary crossroads between tailed phages and herpesviruses! www.nature.com/articles/s41...
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- Reposted by Miguel Gómez-Raya🚀New preprint from our lab! I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡 Continue reading (🧵)
- Reposted by Miguel Gómez-RayaWhat is the best strategy to win any contest? Eliminate your opponents of course. Recently, my friend @fernpizza.bsky.social showed how plasmids compete intracellularly (check out his paper published in Science today!). With @baym.lol, we now know they can fight. www.biorxiv.org/content/10.1...
- Reposted by Miguel Gómez-RayaHot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/ www.science.org/doi/10.1126/...
- Reposted by Miguel Gómez-RayaHow do cells adapt morphology to function? In a 🔥 preprint by @zjmaggiexu.bsky.social , with @dudinlab.bsky.social and @amyweeks.bsky.social , we identify a self-organizing single-cell morphology circuit that optimizes the feeding trap structure of the suctorian P. collini. 🧵 tinyurl.com/4k8nv926
- Reposted by Miguel Gómez-RayaClone-FISH paper out: Manuscript/resource alert #microsky 🦠 We present a collection of 30 E. coli (CloneFISH) cultures, each carrying a plasmid for the heterologous expression of a (near) full-length 16S rRNA gene from one of 30 lineages of archaea, including 17 yet uncultured ones.
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- Reposted by Miguel Gómez-Raya📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social www.findaphd.com/phds/project... 📅 January 7, 2026 Please RP🙏thx!
- Reposted by Miguel Gómez-RayaAn Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...
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- Reposted by Miguel Gómez-RayaThis paper has been a must! Great collaboration with @mkrupovic.bsky.social and @yifanzhou.bsky.social, a N&V by a legend of halophilic archaea tinyurl.com/yc3dcv72, and one picture of one of our expeditions to Dallol making the cover of the November issue of @natmicrobiol.nature.com rdcu.be/eLtCH
- Reposted by Miguel Gómez-Raya🚨Our collaboration with @centriolelab.bsky.social & @gautamdey.bsky.social is out today in @cp-cell.bsky.social We show that #Expansion #Microscopy is a broad-spectrum modality for Euks, enabling 3D phenotypic maps rooted to phylogeny. #ProtistsOnSky #SciComm #SciSky www.cell.com/cell/fulltex...
- Reposted by Miguel Gómez-RayaLab’s first paper is out!! We show the first structures of #Asgard #chromatin by #cryo-EM 🧬❄️ Asgard histones form closed and open hypernucleosomes. Closed are conserved across #Archaea, while open resemble eukaryotic H3–H4 octasomes and are Asgard-specific. More here: www.cell.com/molecular-ce...
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- Reposted by Miguel Gómez-RayaOur work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology! @mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social www.nature.com/articles/s41...
- Reposted by Miguel Gómez-RayaCheck out our paper on intricate nested interactions between viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts. Excellent collaboration with @deemteam.bsky.social, @anagtz.bsky.social and Michail Yakimov Free access link: rdcu.be/eLtCH 🧵 by @yifanzhou.bsky.social 👇
- Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology! @mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social www.nature.com/articles/s41...
