Steve Quinn
Single molecule biophysicist at the University of York, UK. Alzheimer’s disease, biophotonics, diagnostics, protein-membrane interactions, smFRET.
- Congrats to Jamie et al! Our latest @york.ac.uk work dissecting the structural landscape of the Rep Helicase is now out in Nucleic Acids Research! 🧬🔬 @timcraggs.bsky.social @agnesnoy.bsky.social @bpsiyork.bsky.social @dr-mahmoud.bsky.social @single-mole.bsky.social 👇 tinyurl.com/bdznxur3
- Our latest paper is in ACS Omega! We reveal how detergents remodel membranes before solubilization using a simple fluorescence dequenching assay, catching nanoscale intermediates. 👇 pubs.acs.org/doi/10.1021/... Congrats to Claudia, Katie and 3 UG students (Emily, Lauryn and Chris) from the team!
- 🚨Only 2 more weeks to apply for our fully-funded PhD position @york.ac.uk! Want to pioneer a blood test for dementia, detect single molecules & spend time in industry with @ei-science.bsky.social?! Apply by 4th Dec: tinyurl.com/yt36p9tx It doesn't get any more EXCITING! 🔬🩸🧪
- Reposted by Steve Quinn📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social www.findaphd.com/phds/project... 📅 January 7, 2026 Please RP🙏thx!
- 🔬Want to develop a blood test for dementia? A fully funded PhD position is available in our lab to probe and detect single molecules! Join our team @york.ac.uk ! Find out more & apply by 4th Dec: tinyurl.com/yt36p9tx @ybri-uoy.bsky.social @ei-science.bsky.social @timcraggs.bsky.social
- We are delighted that our latest @york.ac.uk & @ybri-uoy.bsky.social work showcasing our photonic biosensor for Alzheimer's disease blood biomarkers has been published in @optica.org! 👇 opg.optica.org/optica/fullt... Thanks to @alzheimerssoc.bsky.social & @alzheimersresearchuk.org for support!
- Congratulations to Dr Fran D'Rozario from our @york.ac.uk team for successfully defending her thesis! Thanks also to Prof Paula Mendes & @bpsiyork.bsky.social for examining, and to Prof Steve Johnson for supervising. Well done Fran!

- New preprint! 🚨 I'm delighted to share our latest @york.ac.uk & @ybri-uoy.bsky.social pre-print: "Detergent-Triggered Membrane Remodelling Monitored via Intramembrane Fluorescence De-Quenching." Congratulations to Claudia from the team on her first manuscript! 👇👇 www.biorxiv.org/content/10.1...
- We are delighted to announce that our latest work - a handheld photonic biosensor for Alzheimer's disease blood biomarkers - has been accepted for publication in Optica! Check out the pre-print... 👇👇 arxiv.org/abs/2504.08476 ...and BBC story below: www.bbc.co.uk/news/uk-engl...
- 🚨 New preprint!🚨We introduce a DNA-scaffold strategy for efficient dye labelling of structured RNAs, enabling #smFRET studies of freely-diffusing SARS-CoV-2 pseudoknots🧬 👉 biorxiv.org/content/10.1... #smFRET #RNA #biophysics #SARSCoV2 #singlemolecule #Covid
- 🧬New Pre-Print!🧬 PhD candidate Fran D'Rozario explores how pH-sensitive DNA triplexes retain reversible switching in solution, and when densely immobilized on surfaces - a step towards hybrid electronic DNA devices? 👇👇 biorxiv.org/content/10.1... #DNAnanotech #bioelectronics #smFRET #DNAmachines
- New job opportunity! The Lindemann Trust is recruiting 2 freelance roles: a Trusts and Grants Fundraiser and Philanthropy Events Fundraiser. For more info, and to apply, visit: lindemanntrust.co.uk/support/ Closing date: Tuesday 19th August.
- 🚨New Preprint! Latest research led by @jemmabetts.bsky.social & @chillzaa.bsky.social reveals the structure of a protein-dependent riboswitch, revealing new mechanistic principles that could inspire novel antivirals! Thanks @ukri.org, @ei-science.bsky.social, @ybri-uoy.bsky.social for support! 🔬
- New preprint alert! 🚨👇 I'm delighted to share the latest research from @jemmabetts.bsky.social in our group: ‘A new protein-dependent riboswitch activates ribosomal frameshifting’. Huge congratulations to Jemma for the first manuscript of her PhD! ✨ www.biorxiv.org/content/10.1...
- Congratulations to Dr Sarah Graham @york.ac.uk #Physicsoflife group for successfully defending her thesis! Thanks also to Dr Tara Sabir & @agnesnoy.bsky.social for doing the honours as examiners, @bpsiyork.bsky.social for co-supervising & @chillzaa.bsky.social for all the help along the way!

- The heat was brutal, and the second half was gruelling. So chuffed to have made it through the 26.2 miles! Thanks London and @alzheimersresearchuk.org that was a blast!
- 26.2 hours until until I take on #londonmarathon2025 , running for @AlzResearchUK ! Every step is for a future free from dementia. Let’s do this! justgiving.com/page/runlabrun
- We are excited to share our latest pre-print, now available on @arxiv.bsky.social: our latest photonic biosensing platform for blood-based Alzheimer's Disease biomarker detection! Check it out! 👇👇 arxiv.org/abs/2504.08476 @ybri-uoy.bsky.social
- It’s finally time for the taper! My legs are delighted to share that they have completed the final long training run! London Marathon 2025 is just 2 weeks away! #inpain 🏃 Donations to @alzheimersresearchuk.org , who fund critical research are enormously appreciated! justgiving.com/page/runlabrun
- Blood biomarkers are beginning to revolutionize #Alzheimers diagnosis and have potential to offer early detection. Could emerging blood test technologies transform patiet care? Check out my editorial, out now in @jprecmed.bsky.social 👇👇 tinyurl.com/nwk34t7k #Biomarkers #Dementia #Diagnostics
- Excited to be running #londonmarathon 2025 in support of @alzheimersresearchuk.org! The charity does so much to support ground-breaking dementia research! Any support for their mission, however small, would be massively appreciated and treasured so much! www.justgiving.com/page/runlabrun
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- We’re on the way to #Birmingham for #ARUKConf2025! Excited to showcase our latest tech for blood based biomarker analysis and learn more about the latest developments in #dementia research! Come chat with us - we’re a friendly bunch! 🔬📈📊🥼
- We're all set for @biophysicalsoc.bsky.social #bps2025! Come learn more about our team's biosensing innovations for blood-based biomarker detection! Katie will showcase a new nanopillar-based approach for multiplexed analysis of Alzheimer's biomarkers! Sunday Feb 16th @ 9.45! 📊🩸🧪
- Reposted by Steve Quinn🚨 I'm delighted to announce a fully-funded PhD studentship (October 2025 entry) in collaboration with the Pirbright Institute. Are you interested in FMDV genome replication and packaging? Fascinated by structure and RNA-protein interactions? More info here: www.findaphd.com/phds/project...
- Our latest work showcasing a resonant Young's slit interferometric biosensor for the ultrasensitive detection of Alzheimer's disease biomarkers has been accepted for publication! Congrats to Stefanus, Katie & Augusto from the team! Thanks to @alzheimerssoc.bsky.social & @york.ac.uk for support! 🔬🧪
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- We have 4 fully funded #PhD positions available in York! Interested in single molecule biophysics, structural biology, biochemistry and/or physical chemistry? Get in touch! We have state-of-the-art labs in a fun-filled city! Come join us! DM for more or check out: sites.google.com/york.ac.uk/q...