Kaitlin McCreery
We study the cell nucleus and the tissue microenvironment, driving dynamic cell mechanics. Multiscale Bioengineering Lab at College of Engineering & Mathematical Sciences at the University of Vermont. mccreerylab.com
- Reposted by Kaitlin McCreeryYou don't understand that's my emotional support bag of loose PCR tubes
- Reposted by Kaitlin McCreerySleep matters for joint health! In our new paper led by Dr Liz Rowlands, we studied sleep habits of 500,000 people. Osteoarthritis risk was highest with <6 hours of nightly sleep and significantly increased by shift work. acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
- Reposted by Kaitlin McCreeryInterested in the biophysics of organoids? We just published a review in Dev Cell—take a look! dlvr.it/TPyTb8 #Organoids #Biophysics
- Reposted by Kaitlin McCreeryAppreciate Quanta for shining a light on our joint work with Simon Gsell, Sham Tlili (@shamtlili.bsky.social), and Matthias Merkel (@merkellab.bsky.social).
- Biophysicists are realizing that there is an undervalued element at play in early development: Aside from genes, mechanical forces also steer the growth of embryos. @annademming.bsky.social reports: www.quantamagazine.org/genes-have-h...
- Reposted by Kaitlin McCreery💫NEW: @sarawickstrom.bsky.social @katemiro.bsky.social & co show that mechano-osmotic changes in the #nucleus induce general #transcriptional repression and prime #chromatin for cell fate transitions by relieving repression of specific differentiation genes. #pluripotency bit.ly/3VMcyNZ
- Reposted by Kaitlin McCreerySee this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
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- Reposted by Kaitlin McCreeryAmazing to have our work finally out!!! 😍🤩😍
- How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
- Reposted by Kaitlin McCreeryMechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells @natcellbio.nature.com @sarawickstrom.bsky.social @akistubb.bsky.social www.nature.com/articles/s41... www.nature.com/articles/s41...
- Our paper is out in Nature Cell Biology! 🚀 Growth factors, mechanical forces, and osmotic stress work together to guide stem cell differentiation. Delighted to see these discoveries out in the world 🔥
- How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
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- Reposted by Kaitlin McCreeryAnother paper bluetorial! Today: how does the spatial location of genes influence their function? (1/n) www.nature.com/articles/s41...
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- Our review "Measuring and manipulating mechanical forces during development" is now published in Nature Cell Biology! #Mechanobiology #DevelopmentalBiology
- Happy to share our review on methodology for measuring and manipulating mechanical forces with specific focus on developmental biology! Congrats to authors @clemvilleneuve.bsky.social @mccreery.bsky.social and hats off to the community for developing awesome tools www.nature.com/articles/s41...
