@KingOfPathogens
🏴 Cytokines Parasites
- Reposted by @KingOfPathogensTo mark the highlights of AI use in research i thought it would be good to commemorate the two year anniversary of this crown jewel. Published in Frontiers in Cell and Developmental Biology. Frontiers are frequently front runners in this type of scanfals. Who remembers #ratgate ?
- Reposted by @KingOfPathogensA brief burst of sun in the Skagit Valley and suddenly everything came alive—owl Harrier fights, wings flashing, fields glowing. Sunset hit different tonight. #Skagit #PNW #birds #photography #wildlife
- Reposted by @KingOfPathogensA must-read !
- In a new article with Kevin Groen, we review the most recent scientific developments relating to autoantibodies targeting type I interferons and their impacts on severe viral disease: doi.org/10.1016/j.co...
- Reposted by @KingOfPathogensKey Takeaways from NIH Director Bhattacharya's hearing from Miriam and Bethesda Declaration whistleblower Jenna Norton (speaking in personal capacity). Our analysis? "Oof." (1/3 🧵)
- Reposted by @KingOfPathogensHe may be an idiot but he sure has perfect ‘scooting’ form. 😂
- Reposted by @KingOfPathogensNice summary of a paper that revealed a healing role for a fungi that is part of the gut commensal microbiome 🧵🧪#MicroSky
- Reposted by @KingOfPathogensCongrats to Mei Li and team for this nice story in @natimmunol.nature.com showing "that TSLP from keratinocytes activates transitional DC-derived DC2 to promote GATA3+ regulatory T cells and mediate immunosuppression during inflammation and cancer". www.nature.com/articles/s41...
- Reposted by @KingOfPathogensReviewers are the soul of any scientific journal and I want to thank you those who reviewed papers in 2025 for #mSphere. Exciting things to come from mSphere. Stay tuned @asm.org journals.asm.org/doi/10.1128/...
- Reposted by @KingOfPathogensNearly 15% (over 10,000 people) of the total number of Ph.D.s in science, technology, engineering, and math or health fields employed at the end of 2024 left their jobs in 2025. This is a science extinction event in the US. Rebuilding the lost expertise will take decades
- Wow. This is devastating. www.science.org/content/arti...
- Reposted by @KingOfPathogensAlex Pretti’s coworkers take a moment of silence this morning
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- Reposted by @KingOfPathogensAnnouncing the recipients of the 2025 AAI Public Service Award: 🔬 Dr. Marcia McNutt, President, NAS 🏛️ Sen. Tammy Baldwin (D‑WI) Both leaders have shown extraordinary commitment to protecting biomedical research, advancing NIH funding, and championing scientific integrity: ow.ly/b7TA50Y3WnC.
- Reposted by @KingOfPathogensHello world! I am excited to announce my lab is open at the University of Utah in the Department of Biochemistry. We are looking for scientists at all levels interested in studying host-virus interactions in both bacteria and animals. Come join us in beautiful Utah! (photo is 10 steps from lab)
- A historical view of power and ego in leadership. www.nytimes.com/2026/01/23/o...
- Reposted by @KingOfPathogensYet another reason to screen people over 65 years of age for type I IFN autoantibodies: Type I IFN autoantibodies underlie chikungunya live-attenuated vaccine encephalitis | PNAS www.pnas.org/doi/10.1073/...
- Reposted by @KingOfPathogensIt's been almost a century since scientists first demonstrated how to clean the air of measles and other pathogens with ultraviolet light, as I wrote in Air-Borne. Here's the latest guidance from @donmilton.bsky.social & other experts.
- Innate Recognition for the win! @aai.org @cytokinesociety.bsky.social www.japanprize.jp/en/press.html
- Reposted by @KingOfPathogensFuture generations will look back at what's happening in Minneapols andnreact the same way when we see these pictures. upload.wikimedia.org/wikipedia/en... www.dispatch.com/gcdn/authori...
- Reposted by @KingOfPathogensHow sad is this? The CDC closed its FOIA office, so this story could only be published because a Danish journalist provided Rolling Stone with the documents, after obtaining them through a freedom of information request to the University of Southern Denmark www.rollingstone.com/politics/pol...
- Reposted by @KingOfPathogensVaccination against whooping cough, RSV and flu during pregnancy saves babies lives, but expectant parents are sometimes unsure. How do I know it's safe? Will it protect my baby? To answer these questions, we've created www.vaccinesinpregnancy.org #ObGynSky #MedSky #ImmunoSky 1/
- Reposted by @KingOfPathogensThe Barber lab is looking to hire post-docs to work on #tuberculosis #immunology using murine and NHP models. BSL3 experience not required. Check out our lab in the NIH intramural program in Bethesda MD!
- Reposted by @KingOfPathogensRegistration and abstract submission is now open for the 2nd Biennial Cryptosporidium Meeting is now open. Deadline April 1st: eventbrite.co.uk/e/2nd-bienni... Submit your abstract by Feb 15th. See you in Edinburgh, May 24th-26th, 2026!
- Reposted by @KingOfPathogensWhat goes into planning the world's largest all-immunology event? Join AAI President Dr. Uli von Andrian and Program Chair Dr. Shekhar Pasare for a preview of #IMMUNOLOGY2026™! 🧬 Presidential Symposium 🔬 Special Sessions 🎓 Trainee Programs 🔗 immunology2026.aai.org
- 🎉 We're back with our first episode of 2026! Drs. Ulrich von Andrian and Shekhar Pasare from @aai.org discuss what to expect at #IMMUNOLOGY2026™! Listen now: bit.ly/3ZgtkGo
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- Reposted by @KingOfPathogensPeer Review is broken because a generation of Editors were trained that peer review is sacrosanct. Thus we have Editors who are clerks, sending and re-sending manuscripts to reviewers until they are happy. That's not the job. Be an Editor, not a clerk. Use your skill and judgement. Make decisions.
- Reposted by @KingOfPathogensChinese Universities Surge in Global Rankings as U.S. Schools Slip www.nytimes.com/2026/01/15/u... current govt policies are probably not directly responsible for this but the they will certainly not help and will accelerate the downward spiral
- Reposted by @KingOfPathogensProject 2025 is obsessed with China as our biggest international threat and their solution to that problem is to attack US higher education. That’s thinkin’.
- Reposted by @KingOfPathogensft. F. Li, B. Poudel, M. Andrade-Silva, J. Wu, A. Raman, J. Wahba, @ally-vassalotti.bsky.social, C. Li, A. Abedini, K. Klötzer, @ksusztak.bsky.social (Kidney), J. Miner (Rheum), E. Cruz-Morales & @kingofpathogens.bsky.social (Vet) www.ahajournals.org/doi/10.1161/...
- Who wants to learn more about the IL-17 family and what limits its activities? @cytokinesociety.bsky.social @aai.org www.nature.com/articles/s41...
- Who wants to learn more about the IL-17 family and what limits its activities? @cytokinesociety.bsky.social @aai.org www.nature.com/articles/s41...
- Reposted by @KingOfPathogensFDA deletes warning on bogus autism therapies touted by RFK Jr.‘s allies arstechnica.com/health/2026/...
- Reposted by @KingOfPathogensEach Friday, I write a briefing on what is happening to American science & higher ed. 🧪 This was Year 2, Week 2: - science budgets avoid catastrophic cuts, but NOT okay - vaccination schedule hijacked & kids will suffer - university mergers in Oregon & so much more buttondown.com/liminalcreat...
- Reposted by @KingOfPathogensNew year, new paper! Thrilled to share that our review “Contextualising TH17 cells in cancer” is out now! Congratulations to Declan & team for a fantastic, in depth overview🥳 Go give it a read here: doi.org/10.1038/s415... @natrevimmunol.nature.com @kiroxford.bsky.social
- Reposted by @KingOfPathogensMy main PhD paper is finally out! 🎉 After ~5 years, it’s published today in 𝘕𝘢𝘵𝘶𝘳𝘦 𝘐𝘮𝘮𝘶𝘯𝘰𝘭𝘰𝘨𝘺. @natimmunol.nature.com It all started with an unexpected observation 🔍: 👉 Mice lacking the dendritic cell receptor DNGR-1 developed tumours earlier ⏩ and more frequently 📈 than wild-type mice. 1/11 🧵
- Reposted by @KingOfPathogensNew York Times obituary for my dad. www.nytimes.com/2026/01/02/n...
- Reposted by @KingOfPathogensEssential reading: TIME highlights the legacy of Nobel Prize Laureate and AAI Past President James Allison. Discover how his work on immune "brakes" launched a new era of cancer immunotherapy. Read more: ow.ly/gnAH50XQqGI.
- Reposted by @KingOfPathogensIn this perspective, Ryan Langlois @langloislab.bsky.social suggests that understanding fever’s role in shaping antiviral gene #evolution may illuminate blind spots in our comprehension of host–pathogen interactions and antiviral mechanisms. rupress.org/jem/article/... #InfectiousDisease #Virology
- Reposted by @KingOfPathogensSo excited to share with you our latest work, result of my PhD with Dr.Rejane Rua at the @ciml.bsky.social! 🍾 If you want to brainstorm about bone channels and skull’s contribution to meningeal immunity, have a look! 🔬🧠
- Reposted by @KingOfPathogensThis is an outstanding essay describing some of the important roles and influences of NIH program officers (from an insider perspective). Read! elizabethginexi.substack.com/p/the-quiet-...
- Reposted by @KingOfPathogensTargeting TLR7 or downstream effectors may represent a promising strategy to alleviate chronic pain induced by lupus www.mdpi.com/2073-4409/15...
- Reposted by @KingOfPathogensIL-27 promotes Treg cell expression of CD122 and fitness at homeostasis @pnas.org @kingofpathogens.bsky.social www.pnas.org/doi/10.1073/...
- Reposted by @KingOfPathogensT follicular helper cells adopt alter egos and localize to diverse niches - what gene expression programs distinguish Tfh in the germinal center? After dissociating tissue samples into single-cell suspension, can we infer which Tfh were positioned in GCs? Check out our new preprint! bit.ly/3XVsrCI
- Reposted by @KingOfPathogensCytokines 2026 in Glasgow (Oct 18-21) has an incredible Scientific Organizing Committee! Simon Jones, Iain McInnes, Clare Bryant, Clare Lloyd, and Luke O'Neill creating the program. This one's going to be special. Details: 2026.cytokinesociety.org
- Reposted by @KingOfPathogensUrs Mörbe, William Agace et al. characterize and spatially map the fibroblast landscape within human large and small intestinal gut-associated lymphoid tissues, including Peyer’s patches and isolated lymphoid follicles, during homeostasis and #Crohns disease. rupress.org/jem/article/... #IBD
- In the year that Tregs get the respect they deserve - here is our contribution to help understand what regulates their homeostasis. One for lovers of cytokines and Tregs! www.pnas.org/doi/10.1073/...
- Reposted by @KingOfPathogensThe top 10 people of 2025 @nature.com who shaped science. Recognizes Dr. Susan Monarez, the CDC Director who was "fired for holding the line on scientific integrity" www.nature.com/immersive/d4...
- Reposted by @KingOfPathogensThe United States "is losing its long-held lead as a research powerhouse and collaborator in world science." www.nature.com/articles/d41...
- Reposted by @KingOfPathogensA new review explores one of the themes of my book Air-Borne: our lungs are like the ocean. Both send life into the atmosphere. pubs.acs.org/doi/full/10....
- Reposted by @KingOfPathogensVaccinating newborns against hepatitis B saves lives. Why might a CDC panel stop recommending it? www.cidrap.umn.edu/childhood-va...
- Reposted by @KingOfPathogens🚨 New work out from the Pernas Lab. Congratulations to my labmate Chahat Mehra!! Host organelle - pathogen membrane contact sites!! ER edition! rdcu.be/eRKUM
- Reposted by @KingOfPathogensIn AIR-BORNE, I wrote about the reluctance many scientists had to acknowledge Covid can float to new hosts. Now it looks like something similar may be happening with bird flu, which may be blowing from farm to farm. Story in @propublica.org www.propublica.org/article/bird...
- Reposted by @KingOfPathogensStimulating day at MRC Biomedicine Science Conference. Super keynote from Sarah Teichmann, Entertaining and thought provoking talk from George Davey Smith, MRC Millennium Medal recipient, and amazing views from the loo @mendelrandom.bsky.social @ukri.org
- Reposted by @KingOfPathogensThere's a word for learning from evolution's inventions: bioinspiration. Here's my interactive story on the way animals and plants fuel technological creativity. Gift link: nyti.ms/4otNQyl
- Reposted by @KingOfPathogensNov issue of #Science #Immunology out now! This week: exTH17 cells sustain #IL17 –independent rheumatoid #arthritis; CXCR4+ mesodermal progenitors → rostral blood vessels, prodefinitive hematopoiesis, & postnatal tissue #macrophages; & how #Bcells acquire antigens from #parasites! scim.ag/4qQA6Q6
- Reposted by @KingOfPathogensAfter many rewarding years at @StJudeResearch surrounded by exceptional colleagues & groundbreaking science, I’m delighted to join @fredhutch to push boundaries in viral & cancer immunology. Grateful to St. Jude and looking forward to what’s next at FH! More here: www.fredhutch.org/en/news/cent...
