Jay Hinton
Salmonella admirer & Prof of Microbiology - Working on Salmonella bloodstream infections (iNTS) in sub- Saharan Africa context. Functional genomics. T1D.
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- Reposted by Jay Hinton#NewResearch Diverse genomes of lytic phages are found in bacterial assemblies, challenging assumptions about the nature of the lytic lifestyle. #MicroSky 🦠 www.nature.com/articles/s41...
- Reposted by Jay Hinton#NewResearch The long-term existence of diverse virulent phages within cultures of Escherichia coli and others challenges the virulent–temperate dichotomy and points to non-canonical phage lifestyles. #MicroSky 🦠 @peterdoug.bsky.social @emggroupucph.bsky.social www.nature.com/articles/s41...
- Reposted by Jay HintonFriday we lost a brilliant mind, colleague, and friend to her battle with pancreatic cancer. Those who knew her will remember Helene Andrews-Polymenis for her warmth, generosity and leadership. She will be missed by many. RIP
- Reposted by Jay HintonOur recent paper in npj Antimicrobials and Resistance is a great example of scientific serendipity: after staring at thousands of bacterial growth curves over many studies, we started wondering whether the curve shapes themselves carry mechanistic information 1/9 🦠🧪 www.nature.com/articles/s44...
- Reposted by Jay Hinton#microsky #phagesky The 3rd (? Lost track!) manuscript on a CRISPR/anti-CRISPR -based transposon tool to study gene essentiality in #phages www.biorxiv.org/content/10.6...
- Reposted by Jay HintonThe final form of my 2nd postdoc paper with the Bassler Lab! Turns out our favorite quorum-sensing phage isn’t a one-off, but rather a member of a globally dispersed family of phages that sense a universal autoinducer. #phagesky #microsky journals.asm.org/doi/10.1128/...
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- Reposted by Jay Hinton#MachineLearning methods are used to predict #AntimicrobialResistance #AMR from genomic data. @lbarquist.bsky.social &co show that sampling biases driven by population structure severely undermine the accuracy of AMR prediction models even with large datasets @plosbiology.org 🧪 plos.io/4iZ0zXQ
- Very good news ‼️ fems-microbiology.org/european-aca... @femsmicro.org
- Reposted by Jay Hinton🔔New Preprint🔔 Just posted on Access Microbiology (first time using this platform, seems great!) our work on looking for antimicrobial proteins in snake venom. This is work from the first bit of funding I received and the project (1/3) www.microbiologyresearch.org/content/jour... #MicroSky
- Reposted by Jay HintonNew paper from the lab! Led by Patrick Müller: we show that non-antibiotic compounds — but not macrolide antibiotics — can induce an efflux pump that protects Bacteroidaceae from macrolides. A neat twist on drug–microbe interactions... www.tandfonline.com/doi/full/10....
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- Congratulations to Dr Annis Newman ‼️ It was a pleasure to read Dr Newman’s PhD thesis - and then to spend this morning’s Viva discussing the elegant science she did in @drprernavohra.bsky.social’s group at @edinburgh-uni.bsky.social
- Reposted by Jay HintonIf you’re interested in solving bacterial mysteries, this PhD project is for you! www.findaphd.com/phds/project...
- Reposted by Jay HintonHad such a great time with @jayhinton.bsky.social strolling around Liverpool, discussing science &life, visiting Hinton Lab & other microbiology labs at Liverpool
- Reposted by Jay HintonImpact of Small RNA Sponges on Regulatory RNA Networks in Bacteria #microsky www.annualreviews.org/content/jour...
- Reposted by Jay HintonIt’s not only medications—environmental chemicals can also inadvertently harm our gut microbes. Excited to have contributed a bit to this important study!
- Our paper mapping the effects of hundreds of pesticides and industrial chemicals on gut bacteria is out in @natmicrobiol.nature.com today! Turns out many such chemicals, although labelled as 'fungicides' or similar, can inadvertently inhibit friendly gut bacteria. www.nature.com/articles/s41...
- Reposted by Jay Hinton#microsky #phagesky #phage Anyone who’s tried deleting prophages in the lab by HR knows the difficulties of the task. Here we have an example of how HR-mediated natural transformation might hit the same hurdle in a more native context. academic.oup.com/mbe/article/...
- I took this photo in Dec 2024 - it explains my belief that sunsets are incredible at this time of year… Another calm evening had turned West Kirby’s Marine Lake into a perfect mirror ‼️ 🌇💛 🌇💛 #Sunset #BlueSky #Reflection #GoldenHour #WestKirby #Photography #PhotoOfTheDay
- Reposted by Jay Hintonif you are interested in a PhD in tuberculosis drug discovery, check out our opportunities 🧪🦠 #Tuberculosis lstm.ac/PhD
- The sunsets at this time of year are incredible. Last night’s was unforgettable — the calm evening turned West Kirby’s Marine Lake into a perfect mirror, reflecting the sky back at us. Truly life-affirming 🌇💛 🌇💛 #Sunset #BlueSky #Reflection #GoldenHour #WestKirby #Photography #PhotoOfTheDay
- Reposted by Jay Hinton🚀New preprint from our lab! I am very excited to finally share what has been the main focus of my PhD for the past almost 3 years! It is about viral dark matter and a powerful tool we built to shed light on it. 🧬💡 Continue reading (🧵)
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- Nottingham university to close its Microbiology course ☹️
- Proud to be part of this incredible multidisciplinary team uncovering why some people are NOT infected by Salmonella. This new Wellcome Trust @wellcometrust.bsky.social funding will allow us to uncover why some people naturally resist infection and colonisation by Salmonella Typhimurium.
- NEWS | Professor @jayhinton.bsky.social and an international team have been awarded £4.56M Wellcome Discovery Award to investigate natural human resistance to Salmonella 🔗 bit.ly/4hujsRG @livuninews.bsky.social | #TeamLivUni
- We believe that this colonisation resistance is driven by the human gut microbiota -we will test our hypotheses experimentally & aim to define the mechanisms involved The exciting project builds on outstanding work of @mgibani.bsky.social & team who developed Salmonella CHANTS human challenge model
- Reposted by Jay HintonNEWS | Professor @jayhinton.bsky.social and an international team have been awarded £4.56M Wellcome Discovery Award to investigate natural human resistance to Salmonella 🔗 bit.ly/4hujsRG @livuninews.bsky.social | #TeamLivUni
- Reposted by Jay Hinton🏆 Fighting the Gender Award Gap: Microbiologist Prof Dr Lisa Maier from @unituebingen.bsky.social received the main award of the German Association for #Microbiology and Hygiene at the #DGHM meeting in Jena. Congratulations to @lisamaierlab.bsky.social we are proud of you! 💜 📸 Gabriele Pradel
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- Reposted by Jay HintonI am delighted to be a co-investigator on this newly funded Wellcome Discovery Award. Excited to begin work with the team (including those not on Bluesky!) @jayhinton.bsky.social @roygoodacre.bsky.social @lisamaierlab.bsky.social @blancaps.bsky.social
- NEWS | Professor @jayhinton.bsky.social and an international team have been awarded £4.56M Wellcome Discovery Award to investigate natural human resistance to Salmonella 🔗 bit.ly/4hujsRG @livuninews.bsky.social | #TeamLivUni
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- Reposted by Jay Hintonhosting.northumbria.ac.uk/nu-omics/vom... #phagesky #phage #microsky Come and join us for Viruses of Microbes UK 2026 at @northumbriauni.bsky.social ! Fantastic chance for ECRs to showcase their work 🙂
- 📈 Reported cases of non-typhoidal Salmonella in England rose by 17% — from 8,872 in 2023 to 10,388 in 2024. Main culprits are S. Enteritidis (up 17%) and S. Typhimurium (up 15%), the most common reported serovars www.gov.uk/government/p...
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- Reposted by Jay HintonRegistration & abstract submissions are open for the #Shigella meeting! Travel grants available too! All are welcomed, whether you are active in #Shigella research or interested in the 21st century perspective on this formidable pathogen! 🦠 🧫 #Microsky www.shigella2026.conferences-pasteur.org/home
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- Reposted by Jay HintonWe're looking for a technician at Institut Pasteur for experimental work on satellite-phage-bacteria interactions, working directly with @jmouradesousa.bsky.social and myself in the lab of @epcrocha.bsky.social ! ANR funded. Link to the job emploi.pasteur.fr/offre-de-emp... Thx for sharing!
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- Reposted by Jay HintonA plasmid golden ratio? 🧬 Plasmid copy number ≈ 2.5% of chromosome size—consistent across bacterial species! pmc.ncbi.nlm.nih.gov/articles/PMC... @jerorb.bsky.social 🧪 #microbesky
- 🚨🚨New paper out in @natcomms.nature.com!! Come for the first large-scale analysis of plasmid copy number across species, stay for one of the most intriguing results of my lab: universal scaling laws in plasmid biology! 📈🧬 👉 www.nature.com/articles/s41...
- Reposted by Jay HintonHonored to have received the 2026 ASM Award for Early Career Basic Research. This award is also a recognition of my phenomenal trainees and their hard work. Thank you to the mentors that have supported my career and those who have nominated me for this award. asm.org/press-releas...
- Reposted by Jay HintonDelighted with our new paper on a novel itaconate transporter in the human pathogen Pseudomonas aeruginosa, led by Javeria and Reyme. @ybri-uoy.bsky.social @javeriamehboob.bsky.social @bethkw.bsky.social A duplicated transporter on its way to itaconate selectivity portlandpress.com/biochemj/art...
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- Reposted by Jay HintonAssistant Prof post in bacterial genomics @unibirmingham.bsky.social Come and join us!! @imibirmingham.bsky.social www.jobs.ac.uk/job/DOO184/a...
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- Reposted by Jay HintonGenetic Evidence of Yersinia pestis from the First Pandemic www.mdpi.com/3429378 #mdpigenes
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- Reposted by Jay HintonNew pre-print in the lab! Beautiful work by Francisco Garcia-Rodriguez in collab with @kamovalenz.bsky.social and @joaquinbernal.bsky.social : when macrophages are provided with specific nutrients, Salmonella can bypass its requirement of the T3SS to replicate, a process that occurs within the SCV
- Reposted by Jay HintonA Salmonella T3SS-2 mutant grows fine in spleen macrophages, contradicting tissue culture dogma (PMID: 23236281). This observation was largely ignored, but adding certain carbon sources rescues growth in cultured macrophages, hinting that T3SS-2 may be doing something entirely different in vivo.
- New pre-print in the lab! Beautiful work by Francisco Garcia-Rodriguez in collab with @kamovalenz.bsky.social and @joaquinbernal.bsky.social : when macrophages are provided with specific nutrients, Salmonella can bypass its requirement of the T3SS to replicate, a process that occurs within the SCV
