Axel Montagne
Senior Lecturer & Group Leader @UKDRI @EdinburghUni, @The_MRC CDA Fellow | @USC & @Universite_Caen alumnus | Vascular, Imaging & Dementia 🧠 | Lab - @montagnelab
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- Reposted by Axel MontagneThe BHF-UK DRI Centre for Vascular Dementia Research welcomes Dr Mohamad El Amki(University of Zurich) for the first seminar in our vascular dementia series 🗣️ Don't miss your chance to register at the link below! lnkd.in/ex5M-EZX
- Reposted by Axel Montagne💫 A top highlight from last year was the official launch of our new Centre dedicated to revolutionising understanding and treatment of vascular dementia, in partnership with the British Heart Foundation ♥️ Find out more 👉 youtu.be/g8KLVN1ODfs?...
- 📢 PhD fellowship opportunity in Edinburgh 🏴 Deadline: Friday 9 📅 Apply now 👇🏻
- 🧠 An exciting fully funded 4-year PhD at the Universities of Edinburgh & Manchester with Drs. Ingo Schiessl, Audrey Chagnot, and myself! 📅 Deadline: Jan 9! 📝 Details are below 👇🏻 Please circulate this widely, thanks!
- 🚀 Fully funded 4-yr PhD @edinburgh-uni.bsky.social & @officialuom.bsky.social on the vascular origins of Alzheimer’s (advanced imaging + proteomics) Supervisors: Drs. Axel Montagne, Ingo Schiessl, and Audrey Chagnot Join the VIDA DTC & @alzheimerssoc partnership 👉 www.findaphd.com/phds/project...
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- 🚀 Fully funded 4-yr PhD @edinburgh-uni.bsky.social & @officialuom.bsky.social on the vascular origins of Alzheimer’s (advanced imaging + proteomics) Supervisors: Drs. Axel Montagne, Ingo Schiessl, and Audrey Chagnot Join the VIDA DTC & @alzheimerssoc partnership 👉 www.findaphd.com/phds/project...
- Reposted by Axel MontagneI'm hiring! Come and work with me at UCL to try and understand how the brain's blood vessels go wrong and promote dementia: www.ucl.ac.uk/work-at-ucl/...
- Exciting PhD opportunity in beautiful Edinburgh: discover how ageing and vascular dementia biology maps onto neuroimaging signals. Using cutting-edge spatial transcriptomics + a new TSPO PET ligand, this project probes the immune-vascular mechanisms driving white matter decline. shorturl.at/8fMmA
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- Reposted by Axel MontagneThe #brain is often viewed as rather separate from the rest of body. One way it is separated somewhat is the BBB — the blood-brain-barrier. Fabulous primer by @axelmontagne.bsky.social and Audrey Chagnot www.cell.com/current-biol...
- Excited to share our Current Biology Primer written with Dr. Audrey Chagnot in the Brain-Body Interactions special issue! We discuss how the BBB works, what happens when it breaks down, and why this matters for brain and body health. @ukdri.ac.uk @thebhf.bsky.social shorturl.at/NNc57
- Reposted by Axel MontagneInterested in the heterogeneity of blood vessels in the CNS? Here we review the unique features of the spinal cord vasculature, its barrier properties and neurovascular interactions, highlighting unknown aspects and future research directions. @CRC1366 @erc.europa.eu @immunosens.bsky.social
- Reposted by Axel Montagne🌟 New job opportunity 🌟 Based within the UK DRI at Edinburgh, the Rajani Lab investigates the mechanisms of white matter damage in vascular and other dementias. Find out more and apply via the link 🗓️ Apply by 22 October 2025 📌 Full details 👉 tinyurl.com/22y73642
- Reposted by Axel MontagneCongratulations to Dr Maura Malpetti (UK DRI at Cambridge), who has won the 2025 European Young Researcher Award from the Fondation Recherche Alzheimer in France. 🎉👏 Read the full story 👉 tinyurl.com/243s9tuf
- Reposted by Axel MontagneThe Rajani Lab is hiring again! We are looking for a postdoc to join us at @ukdri.ac.uk @edinburgh-uni.bsky.social to investigate vascular-oligodendrocyte interactions in dementia. Apply here 👇 bit.ly/4nm8csZ
- Reposted by Axel MontagneThe Edinburgh participants at dinner at VasCog!
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- ✨ Preorders are OPEN ✨ My amazing wife just finished her very first children’s book, and I couldn’t be prouder 💛 📚 Preorder until Sept 7 📦 Shipped w/ tracking 🔗 www.etsy.com/shop/ElodieWho She’s poured her heart into this — every preorder, share, & boost means the world 🙌
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- Reposted by Axel MontagneDelighted to share our latest review in Nature Reviews Neuroscience! We examine the growing evidence that vascular dysfunction plays a key role in cognitive decline in ageing and dementia, and argue that preserving/restoring CBF should be central to future therapies. www.nature.com/articles/s41...
- Reposted by Axel MontagneJust over a week left to apply for this position in our lab!
- The Rajani Lab is hiring! We are looking for a postdoc to join us at @ukdri.ac.uk @edinburgh-uni.bsky.social to investigate neuronal activity and white matter changes in vascular dementia. Apply here 👇 bit.ly/44AFJHx
- 🚨 Review Alert *Walking on the tightrope: the shared roles of the bridging pericytes in the brain* Congratulations Audrey Chagnot!! 🥳 Bias aside, this feels like a really meaningful piece for the cerebrovascular field! 😊 www.frontiersin.org/journals/cel...
- Reposted by Axel MontagneThe Rajani Lab is hiring! We are looking for a postdoc to join us at @ukdri.ac.uk @edinburgh-uni.bsky.social to investigate neuronal activity and white matter changes in vascular dementia. Apply here 👇 bit.ly/44AFJHx
- Reposted by Axel MontagneCome and join us in Manchester... We are looking for candidates interested in vascular health and neurodegeneration. This project is specifically exploring how menopause may increase Alzheimer's risk. We also have a postdoc position available: www.jobs.manchester.ac.uk/Job/JobDetai...
- Reposted by Axel MontagneAmazing opportunity! specially looking for neurovascular research junior PIs!!
- Spread the word: The European Center for Angioscience @uniheidelberg.bsky.social continues to grow: We have openings for 2 additional Junior Group Leader positions. Get in touch with us if you are ready to start your own lab. See also corresponding ad in @nature.com: www.nature.com/naturecareer...
- Reposted by Axel MontagneWe're excited to welcome a new Group Leader to our vascular dementia research centre with the BHF🎉👏 Prof Susanne van Veluw's research focuses on cerebral amyloid angiopathy, where amyloid beta accumulates in the walls of the brain's blood vessels👉https://buff.ly/rNxxNRz
- Reposted by Axel Montagne🧠 New paper out in Biogerontology! We reviewed evidence linking circulating immune cells to cSVD features. Thanks to all co-authors, and the journal team! 🔗 link.springer.com/article/10.1... More coming soon! #Neuroimmunology #cSVD #Biomarkers #AgingBrain #Biogerontology
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- Reposted by Axel MontagneOur perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems. @jonykipnis.bsky.social www.nature.com/articles/s41...
- Well done Dany!!! 👏🤩 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
- Reposted by Axel Montagne🧠 PhD position available! Study polypathology in the medial temporal lobe at the Paris Brain Institute with @lemwisse.bsky.social , @nvillain-alz.bsky.social and myself. This exciting project combines neuroimaging, neuropathology and cognition! Please share widely 🙏
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- Reposted by Axel MontagneMicroglia & monocyte-derived cells were long assumed to have similar functions during remyelination. Our new paper @plosbiology.org shows non-redundant roles, with monocytes ultimately inhibiting remyelination. Team effort by Bianca Hill,Rebecca Holloway, Lindsey Forbes,Claire Davies plos.io/3RryCLF
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- Reposted by Axel Montagne"We're poised to treat our first patient, which is really exciting." Prof Chris Shaw, Group Leader at UK DRI at King's, shares how early support from the Institute helped transform his gene therapy research for MND/ALS & FTD into international clinical trials 👇 youtu.be/9eG6M5UPWz4?...
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- Reposted by Axel MontagneOmega 3 could play a vital role in protecting against motor neuron disease, new research led by @adrianisaacs.bsky.social reveals💡 The study in flies and cells found that increasing levels of certain fatty acids prolonged survival. Read more ⬇️
- Reposted by Axel MontagneAstrocytic cannabinoid receptor 1 promotes resilience to stress in males by dampening stress-induced blood–brain barrier alterations 🧪🧠 @caromenard666.bsky.social www.nature.com/articles/s41...
- Reposted by Axel MontagneSo excited to share the work of the fantastic Katarzyna, 1st 🧪PhD student of my lab 🧠, out in @natureneuro.bsky.social 🥂🥳 Cheers to the team, thanks to our precious collaborators and support from @braincanada.bsky.social #CIHR @fondsrechercheqc.bsky.social #newPI www.nature.com/articles/s41...
- Reposted by Axel MontagneReally excited this is out! We found polyunsaturated fatty acids (PUFAs) were beneficial in models of C9orf72 FTD/ALS and the greatest benefit occurred when increasing levels specifically within neurons @ukdri.ac.uk @uclqsion.bsky.social @ucl.ac.uk @cziscience.bsky.social rdcu.be/ebbZf
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- Thank you so much Caroline ! 😁 A lovely city, I will definitely come back and take some time to visit! Very impressed with all your work at @cervo-ulaval.bsky.social (especially Laurence's) and all your fantastic lab members and colleagues over there 🤩 Currently on the bus for my 1st connection 💪
- Reposted by Axel MontagneOne day, I'll finish this illustration, but I keep adding more details... #art #illustration #kidlitart
- Reposted by Axel MontagneFantastic new work led by @milenevandal.bsky.social showing that loss of brain endothelial CD2AP in mice alters memory and cerebrovascular function. Interestingly, mutations in CD2AP are known to predispose to Alzheimer’s disease! #cerebrovascular
- Reposted by Axel MontagneNew paper led by @silvia-anderle.bsky.social Lifestyle matters for genetic Alzheimer’s disease risk: APOE4 reduces neurovascular function most in an already-stressed system, when neurons are active and mice do less exercise. I'll tell you all about it! 🧪 #neuroscience #alzheimers rdcu.be/d74uh
- Shoutout to an amazing team - great science is only possible because of great people! 😍
- Reposted by Axel MontagneGet your cerebral blood flow and metabolism abstracts in for Brain and BrainPET 2025 in Seoul! Deadline Feb 1st!! I’m so excited! www.brain2025.org
- Reposted by Axel MontagneCouple of opportunities up to join the group! One at postdoc level, but open to senior support path. One research assistant role. Please share, or drop a line if you want to learn more! Or just apply! Thanks! elxw.fa.em3.oraclecloud.com/hcmUI/Candid... elxw.fa.em3.oraclecloud.com/hcmUI/Candid...
- Reposted by Axel Montagne2025 off to a decent start...Happy to share my latest first author paper with the brilliant Nela Fialova and @axelmontagne.bsky.social where we sought to identify genes that are frequently altered in vascular cells in CNS disorders across existing datasets. Check it out here!
- 🚨 Latest contribution where we delve into the dementia-related snRNAseq data & spotlight the signature changes in #endothelialcells and #pericytes! Proud of the effort led by Dr. Michael Sewell @pichaelmichael.bsky.social and Nela Fialova. alz-journals.onlinelibrary.wiley.com/doi/full/10....
- Reposted by Axel MontagneNew study on epigenetic regulation of blood-brain barrier development published at @elife.bsky.social elifesciences.org/articles/86978 #cerebrovascular #BloodBrainBarrier
- 🚨 Latest contribution where we delve into the dementia-related snRNAseq data & spotlight the signature changes in #endothelialcells and #pericytes! Proud of the effort led by Dr. Michael Sewell @pichaelmichael.bsky.social and Nela Fialova. alz-journals.onlinelibrary.wiley.com/doi/full/10....
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- Reposted by Axel MontagneAbstract submission for Stem Cell Models of Neurodegeneration 2025 is open until January 31st 2025! Come register and share your work with us! scmnd.com We look forward to hosting you in Edinburgh next year :-) #neuroscience #iPSC #neurodegeneration #stemcells #dementia #organoids
- Interested in pursuing a PhD with Dr Ben Dickie, Dr Harry Pritchard, and me to explore the role of mural cells in Alzheimer’s disease? Feel free to apply or share this opportunity widely! www.findaphd.com/phds/project...
