Philip Hasel
Group Leader and Wellcome Trust Career Development Fellow at the UK Dementia Research Institute at Edinburgh University. Interested in astrocytes at brain borders.
- Reposted by Philip HaselThe first event of 2026 in our seminar series is on Weds 21st January at 2pm. Presented by @philiphasel.bsky.social of @edinburgh-uni.bsky.social, hosted by Dr Ingo Schiessl. Details on poster - all welcome! 🧠 #neuroscienceseminar #neuroscience #manchesterneuroscience
- Reposted by Philip HaselThrilled to wrap up the year and my postdoc work in the Nester lab with this publication 🥳! We show that astrocytic CREB regulates astrocyte calcium and D1-MSN activity to drive behavioral response to cocaine. pubmed.ncbi.nlm.nih.gov/41406210/
- Reposted by Philip Hasel"Defining the molecular identity and morphology of glia limitans superficialis astrocytes in vertebrates" dlvr.it/TPKJSH @liddelowsa.bsky.social @philiphasel.bsky.social & colleagues @cp-cellreports.bsky.social #SfN2025
- Reposted by Philip HaselCheck out our new review article from my lab: doi.org/10.1111/jnc....
- Reposted by Philip HaselFinally it’s here! 🌟⬇️ www.nature.com/articles/s41... I’m sooo excited to share our latest article led by Steve Hill and Isabel Bravo-Ferrer 1- How does the vasculature communicate with astrocytes? 2- Is this communication dependent to what happens in the body. 3- Is it relevant to human diseases?
- Reposted by Philip HaselReally excited to announce that the Holt lab will be starting in January 2026 in the Center for Substance Use Research at Temple University Lewis Katz School of Medicine. Interested in the role of gene regulation, astrocytes, and addiction? I'm hiring at all positions-DM or email me! l-holt-lab.com
- Reposted by Philip Hasel📢 June 8th-9th 2026 Bristol University 📢 We have partnered with @physoc.bsky.social to organise the 2nd meeting Bristol. It is a privilege to announce Professor Baljit Khakh, FRS will join us in the UK. Check out the exciting programme here: www.physoc.org/events/uk-gl... #neuroskyence #glia
- Reposted by Philip HaselThrilled to share our new paper @cp-cell.bsky.social: “Microglia–astrocyte crosstalk regulates synapse remodeling via Wnt signaling.” This work demonstrates the necessity of glia–glia communication and coordination during synapse remodeling. 🔗 www.cell.com/cell/fulltex... Faust et al., Cell 2025
- Reposted by Philip HaselHello world! We just released a thing! In this preprint we provide evidence questioning the ability of the axon initial segment to undergo rapid structural plasticity in intact neurons from mouse, rat, and human cortex.
- Absence of short-term axon initial segment plasticity in human, mouse, and rat cortical circuits biorxiv.org/content/10.1101/202…
- Reposted by Philip Hasel
- Reposted by Philip HaselAstrocytes connect specific brain regions through plastic gap junctional networks biorxiv.org/content/10.1101/202…
- Reposted by Philip HaselExcited to share the preprint for one of my postdoctoral projects in the Nestler lab 🥳
- Reposted by Philip HaselSo grateful to the @wellcometrust.bsky.social for investing in me... believing in me. It's hard to believe in yourself sometimes. Science is going really well and I am thrilled to be back in the lab wellcome.org/research-fun...
- Reposted by Philip HaselAmyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease: @cp-immunity.bsky.social www.cell.com/immunity/ful...
- Reposted by Philip HaselFor those who want a distraction and/ or are interested, here's the latest from the group, led by Phil Braaker www.nature.com/articles/s41...
- Reposted by Philip HaselDear immune/glia lovers of brain, gut and beyond… We’re looking for a lab tech/manager to join our team! Pls see details for application here ucl.ac.uk/work-at-ucl/se… @ukdri.ac.uk @uclqsion.bsky.social - pls help circulate among networks who’d be of interest, thank you!
- Reposted by Philip HaselOur perspective in @natrevimmunol.nature.com on new concepts in neuroimmune interactions that have challenged the old dogma that immune privilege is a result of the isolation of the nervous and immune systems. @jonykipnis.bsky.social www.nature.com/articles/s41...
- Reposted by Philip HaselThrilled to announce that my lab is now open at Ohio State! We study astrocytes as gene therapy targets for brain repair after ischemic stroke and in vascular dementia, developing new viral tools along the way. If you're interesting in joining or collaborating, please reach out! gleichmanlab.com
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- Reposted by Philip HaselWe used microglia replacement to understand the therapeutic and pathologic roles of macrophages in a genetic brain disease 🧠 A 🧵 on my first author work from the Bennett Lab (+ the paper) below! ⬇️ www.cell.com/immunity/ful...
- Reposted by Philip HaselHow does the brain repair myelin after injury? We mapped the full cellular choreography of white matter repair using snRNA-seq + Slide-seqv2, uncovering a type I interferon-driven glial program that recruits lymphocytes to promote remyelination. www.biorxiv.org/content/10.1... Details below 👇
- Reposted by Philip HaselA new study led by @philiphasel.bsky.social reveals the unique genetic profile of astrocytes that form the glia limitans superficialis (GLS), the thin layer of cells that covers the brain and spinal cord 🧠 Dr Hasel spoke to @thetransmitter.bsky.social about his work⬇️
- Master class in single cell genomics analysis from @mrodea.bsky.social
- Reposted by Philip HaselI am #hiring an #MRI #physicist, please consider making an application. The job is based in #Sheffield, with extensive collaboration with #UCL. Opportunity to work at 7T & 9.4T, & undertake human imaging at 3T in parallel with the core preclinincal work. jobsite.sheffield.ac.uk/job/Research...
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- Great story covering our description of the superficial glia limitans! @thetransmitter.bsky.social : www.thetransmitter.org/astrocytes/u...
- Reposted by Philip HaselHave you seen our website: Built and maintained by @drmyelin.bsky.social Check it out 👀 www.glianetwork.org.uk
- Highly recommend Aida and her lab! Apply for this amazing opportunity:
- 🚨 Heads-up: a little over a week to apply for this exciting postdoc opportunity in Edinburgh @edinuni-irr.bsky.social! 🚨 I will be in Liverpool for #biologists100. Happy to chat about the position, our research, setting up a lab, spiny mice, axolotls, and whatnot!
- Reposted by Philip Hasel🚨The first #preprint of the #FalconeLab is OUT!🥹🚨 We found that varicose-projection astrocytes are not a physiological type of #astrocytes but they are rather associated with neuropathology. Read more here, feedback is welcome!! More details👇👇 1/ www.biorxiv.org/content/10.1...
- Reposted by Philip HaselSometimes you have to travel to find the cutting edge of glial biology... This meeting would definitely be worth the trip 👀 www.keystonesymposia.org/conferences/...
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- Reposted by Philip HaselFresh off the press! We found that degeneration in one retina causes astrocytes to respond retinotopically across *both* hemispheres of the brain. Perhaps astrocytes across the CNS are able to coordinate their responses more than we anticipated... www.pnas.org/doi/10.1073/...
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- Our paper on the superficial glia limitans is now published - huge thank you to all co-authors that helped getting this work across the finish line! www.cell.com/cell-reports...
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- Reposted by Philip HaselWe are excited to start the third edition of #AstrocyteCafe on February 6th with a lineup of amazing speakers 🤩 Join us for this monthly seminar series on #astrocyte research, it's online and it's free! To register for the mailing list and receive announcements, click the link in the bio!
- Reposted by Philip HaselHello, everyone! Please enjoy one of my favorite micrographs while I finally get set up over here. Vasculature (magenta, perfused lectin), GFAP (cyan), and cx43 (green) in a conditional astrocyte cx43 knockout mouse, demonstrating that cx43 is lost from astrocytes but not pericytes after tamoxifen.
- Reposted by Philip HaselFirst post at this side. Latest axon diameter action led by Jenea Bin, in collaboration with Nolan, Mobius, Monk, Werner, and Emery labs. www.biorxiv.org/content/10.1...
- PhD opportunity: If you're interested in how astrocytes and the meninges talk to each other and how this is affected in dementia come do your PhD with us in Edinburgh (cc: Karen Horsburgh and Ingo Schiessl)! www.findaphd.com/phds/project...
