Shane Liddelow
Neuroscientist and glial aficionado at NYU Grossman School of Medicine/NYU Langone Health in NYC. Posts in my individual/personal capacity.
My lab is full of awesome people doing amazing stuff - check them out: www.liddelowlab.com
he/him
- AMAZING PAPER ALERT! www.nature.com/articles/s41... congratulations to @margheritazamboni.bsky.social, @ellorens.bsky.social, and the rest of the team. This one is important and opens up lots of opportunityes.
- Read about one of the fantastic postdocs in the lab - @pryprk.bsky.social. Thanks to The Scientist for running this exciting series! Priya is on the job market atm - so keep your eyes peeled for exciting things to come from her lab soon! :-)
- I was featured on The Scientist as a part of their 'Postdoc Portraits' series where I spoke about my scientific career path and ongoing work on oligodendrocyte dysfunction in neurodegeneration. Check it out! www.the-scientist.com/postdoc-port...
- #SfN #SocietyForGlia #Astrocytes ENDING STRONG in Astrocyte land here in San Diego. Thanks for being an amazing community, and apologies (one last time) for anyone I missed! Please comment below with extra awesome astrocyte sessions. See you in 2026!
- #SfN #SocietyForGlia STARTING NOW! Ending strong with the last www.liddelowlab.com presentations of the week. @pryprk.bsky.social talking about a world first mouse model for XDP... and OLIGODENDROCYTES! @melcooperphd.bsky.social presenting on astrocyte networks in the mouse forebrain.
- PREPRINTS ON THEIR WORK: Priya - www.biorxiv.org/content/10.1... and www.biorxiv.org/content/10.1... (press - www.npr.org/2024/10/07/n...) Melissa - www.biorxiv.org/content/10.1... (press - www.thetransmitter.org/astrocytes/a...)
- #SfN25 #SocietyForGlia #Astrocytes IT'S A BIG DAY - if you're unsure what do do this afternoon - it seems just going to poster row C is the best way to spend some time! as always, apologies to those I have missed - please comment below with more sessions and presentations!
- IT'S A BUSY AFTERNOON FOR THE LAB! @mrodea.bsky.social - astrocyte chromatin in reactive astrocytes across the forebrain Nick Kathman - COCKROACH BRAIN ALERT! (is this the largest single cell atlas of an insect brain?) @liddelowsa.bsky.social - multiomic approaches to study astrocyte reacitivity
- Reposted by Shane LiddelowIt's a packed day for our researchers at #SfN25. Come say hi!
- #SfN25 #SocietyForGlia #Astrocytes Monday is a BUSY day - see you all out there! (apologies for anyone's presentation I missed - please comment below with details)
- #SocietyForGlia #SfN25 #Astrocytes Sunday is a rest day for astrocytes it seems - but still lots of cool stuff to go and see. Apologies again for anyone I missed - please link your presentations below
- #SocietyForGlia #SfN25 #Astrocytes Astrocyte presentation round up for Day 1. Sorry if I missed anyone, please comment below with others! See you about the conference
- #SfN25 #SocietyForGlia #Astrocytes @borderbiologist.bsky.social presenting now! Come and learn about a new function for a substate of reactive astrocytes - antigen presentation!
- Reposted by Shane LiddelowVery happy to have contributed to this new review on Lewy body dementia in @thelancetneuro.bsky.social led by Sonja W. Scholz. We highlight the latest advances in genetics and pathology. @liddelowsa.bsky.social Check it out! www.sciencedirect.com/science/arti...
- Reposted by Shane LiddelowIn case you were wondering what to do with precisely 150 minutes of your existence @sfn.org #SfN25 #SanDiego. Join our mini-symposium Single-Cell Multiomics in CNS Injury and Recovery. Guaranteed to contain many glial cells and at least a neuron. I am Co-chairing with Naomi Habib
- @sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below. Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social. (1/2)
- @sfn.org #SfN25 #SanDiego starts this Saturday. The lab is going to be there in full force - see our presentations below. Represented this year by @borderbiologist.bsky.social, Nick Kathman, @mrodea.bsky.social, @melcooperphd.bsky.social, @pryprk.bsky.social, @kerrylimberg.bsky.social. (1/2)
- (1/2) preprints: @melcooperphd.bsky.social - astrocyte networks pubmed.ncbi.nlm.nih.gov/40777296/ @mrodea.bsky.social - single cell analysis & diversity www.biorxiv.org/content/10.1... @pryprk.bsky.social - XDP www.biorxiv.org/content/10.1..., www.biorxiv.org/content/10.1... See you in San Diego
- (bonus) thanks to the amazing @droligo.bsky.social and @amygleichman.bsky.social the social aspects of glial biology will be strongly represented. (thanks also to @plasmidsaurus.bsky.social & Avantor for supporting our community!)
- Reposted by Shane LiddelowIf you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!
- Reposted by Shane LiddelowOur latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com www.nature.com/articles/s41...
- Reposted by Shane LiddelowOligodendrocytes support functional development of subcortical premotor neurons and navigation biorxiv.org/content/10.1101/202…
- We've been doing some amazing stuff outside the astrocyte realm. Check out our latest Oligo investigation led by @pryprk.bsky.social !
- I am proud to share our work on X-linked Dystonia-Parkinsonism — a rare neurodegenerative movement disorder driven by a SINE-VNTR-Alu retrotransposon insertion in the TAF1 gene. Read our two companion papers: 🔹 www.biorxiv.org/content/10.1... 🔹 www.biorxiv.org/content/10.1... 🧵 Highlights below!
- Reposted by Shane LiddelowAstrocyte networks are much larger than previously thought, which “flips the way we think about astrocytes and what their networks may mean,” says @liddelowsa.bsky.social. By @callimcflurry.bsky.social #neuroskyence www.thetransmitter.org/astrocytes/a...
- Great story in the @thetransmitter.bsky.social today by @callimcflurry.bsky.social. It was fun chatting about @melcooperphd.bsky.social's new research on astrocyte networks. Read the story here: www.thetransmitter.org/astrocytes/a... Read the preprint here: www.biorxiv.org/content/10.1...
- A fantastic time with an excellent group of trainees at the @neurochemistry.org Advanced School. Let the conference begin!
- are you a PD in the glia (or neuroscience) space? Do you want to come to NYC and give a lecture and meet some amazing faculty here at @nyumedpostdocs.bsky.social? LAST WEEK TO APPLY to be a SPiNES speaker for our next season. Details and apply here: med.nyu.edu/departments-... COME AND WOW US!
- The American Society for Neurochemistry (ASN) and the International Society for Neurochemistry (ISN) are hosting a discussion on autism, with clinical, research, family, & pharma perspectives. August 17, 2025 2-4 PM Hunter College, West Room 714 FREE Registration recommended: lnkd.in/dJY7hp-b
- Talks will be followed by audience Q&A Speakers: Dr Mollie Lobl, Pediatrician, Montefiore Einstein Alison Singer, Pres &Co-founder, Autism Science Foundation Dr Chiara Manzini, Assoc Prof, Rutgers U Dr Karin Knobe, Global Head of Dev, Rare Diseases, Sanofi Dr Annie Maguire, Postdoc, Einstein Med
- #GliaPapers #GliaAugust2025 @wiley.com AUGUST COVER Oligodendrocyte binds to laminin on the perivascular basement membrane in the murine cortex at the age of postnatal day 16 (red: CC-1; green: laminin alpha-2; blue: DAPI). (see Sasaki B, et al, doi.org/10.1002/glia...)
- #GliaPapers #GliaAugust2025 @wiley.com REVIEW Gonçalo Ferreira, Luísa Pinto Neural stem cell-derived astrogliogenesis: the hidden player of the adult hippocampal cytogenic niche onlinelibrary.wiley.com/doi/10.1002/...
- #GliaPapers #GliaAugust2025 @wiley.com RESEARCH Ziwan He, …, Zhihui Huang, Yongjie Wang Interplay between Schwann cells and peripheral cancers: mechanisms and therapeutic targets in cancer progression onlinelibrary.wiley.com/doi/10.1002/...
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View full thread#GliaPapers #GliaAugust2025 @wiley.com m RESEARCH @micaelaoreilly.bsky.social , …, Veronica Tom Microglial IKKβ alters central and peripheral immune activity at distinct time points after spinal cord injury onlinelibrary.wiley.com/doi/10.1002/...
- Reposted by Shane LiddelowAstrocytes connect specific brain regions through plastic gap junctional networks biorxiv.org/content/10.1101/202…
- fantastic work from @melcooperphd.bsky.social - what are these beautiful networks doing in our brains?
- Astrocytes connect specific brain regions through plastic gap junctional networks biorxiv.org/content/10.1101/202…
- Was a lot of fun working on this piece with Ben Clayton for @annualreviews.bsky.social Reactive astrocyte heterogeneity is a thoroughly exciting and complicated problem... lots of exciting discoveries in recent years. www.annualreviews.org/content/jour...
- On now, last session of #Glia2025, and last presenter from the lab. S26 | Exploring glial diversity using single cell and spatial genomics @mrodea.bsky.social 10:00 S26-01 Multi-omic definition of astrocyte diversity in the healthy and inflamed brain
- #glia2025 Liddelow Lab presentations start today! PS2 | Poster Session II Wednesday, 9 July 2025, 13:00 - 16:00 Room: Hall Garden Level T11-059B Understanding specific neuron-astrocyte interactions in neuroinflammation @sciencelemon92.bsky.social www.liddelowlab.com/francesco-li...
- And a special bonus for #EuroGlia @gliameeting.bsky.social in #Marseilles next week - all the abstracts of the fantastic presentations are available in #Glia onlinelibrary.wiley.com/toc/10981136... See you all in a few days - safe travels
- #GliaPapers #GliaJuly2025 JULY COVER Stochastically labeled astrocytes (cyan) and Müller glia (magenta) contacting blood vessels (orange) and neural cell bodies and axons bundles (green) in a mouse retina. (see Holden, JM, et al, doi.org/10.1002/glia...)
