Mireya Plass
Associate professor at Universitat de Barcelona.
Studying post transcriptional regulation in single cells and Alzheimer's Disease. iPSCs, gene regulatory networks, bioinformatics, systems biology
plasslab.com
- Reposted by Mireya PlassCellRank protocol now in @NatureProtocols! 🎉 @PhilippWeiler's detailed guide shows how to: - Integrate velocity, pseudotime & time points - Infer cell fate probabilities - Analyze lineage priming at scale Great complement to our CellRank 2 paper! 📖 www.nature.com/articles/s41...
- Reposted by Mireya Plass⏳¡Cuenta atrás para el evento 'El Proyecto Genoma Humano, 25 años después'! El investigador @rodericguigo.bsky.social (@crg.eu), que formó parte de este gran hito biomédico, nos contará por qué supuso un antes y un después en la biología ¡No os lo perdáis!👇 🔗 www.cnag.eu/events/el-pr...
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya PlassPlease share🙏: Our lab opens 2 PhD positions to investigate fungi's evolution: #Barcelona Wet lab in Biochemistry/Structural Biology of cryo-tolerant fungi www.upf.edu/documents/d/... Computational in Physical Chemistry of cellular processes under extrem environments www.upf.edu/documents/d/...
- Reposted by Mireya PlassFrom a personal POV, tagging along with @martaig.bsky.social and @aelek.bsky.social while they developed this project has been one big learning opportunity. In Nematostella biology, clever omics, evo-devo, and more. And the paper certainly reflects all of that. Go check it out!
- Excited to share the final version of our study on Nematostella cell type regulatory programs. Part of our @erc.europa.eu StG project, this was a challenging 5-year effort extraodinarily led by @aelek.bsky.social and @martaig.bsky.social. www.nature.com/articles/s41...
- Reposted by Mireya PlassExcited to share the final version of our study on Nematostella cell type regulatory programs. Part of our @erc.europa.eu StG project, this was a challenging 5-year effort extraodinarily led by @aelek.bsky.social and @martaig.bsky.social. www.nature.com/articles/s41...
- Reposted by Mireya PlassLovely Xmas gift 🎄—our paper is out today in @natecoevo.nature.com www.nature.com/articles/s41...! Huge thanks to everyone who made it possible, especially @aelek.bsky.social and @arnausebe.bsky.social
- Great work showing the power of scATAC-seq to decode ontogenetic relationships! Maybe I will check chromatin after all...
- Lovely Xmas gift 🎄—our paper is out today in @natecoevo.nature.com www.nature.com/articles/s41...! Huge thanks to everyone who made it possible, especially @aelek.bsky.social and @arnausebe.bsky.social
- Awesome talk from @akshayjg.bsky.social at the Jornades de Bioinformàtica i Genòmica presenying our work on Alzheimer's disease using iPSCs and scRNAseq.
- Reposted by Mireya PlassWe are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
- Reposted by Mireya PlassWant to image cells protecting the embryo during early development? We're hiring! 1 Postdoc, 1 PhD student, and 1 Research Technician. Come to Barcelona! www.embryobioimaging.com
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya PlassHey everyone! I’m excited to share that one of my thesis projects was just published in @currentbiology.bsky.social and featured on phys.org! In this paper, we use an old statistical approach developed by the US Navy in WW2 to predict the aquatic habits of various dinosaurs and marine reptiles 🦖🐊
- Reposted by Mireya Plass¡Ya llevamos 212.352€ recaudados! Estamos más cerca que nunca de lograr crear el algoritmo capaz de anticiparse al Alzheimer. Ayúdanos a seguir investigando 🧠🔬. Dona ahora en anticiparsealalzheimer.org
- Reposted by Mireya Plass[Not loaded yet]
- 🚨Interested in studing RNA regulation & neurodegeneration in single-cells? Join my lab @ub.edu in Barcelona! We are looking for a junior postdoc to apply for a Juan de la Cierva fellowship. Both computational and hybrid candidates are welcomed! Get in touch to discuss the project & details
- Reposted by Mireya Plass🚨 We're hiring! 🚨 Our lab at the University of Málaga, Spain🇪🇸 is looking for a bioinformatician researcher for a postdoc position (1+1 years). Check the ad, and if you're interested, get in touch! 📅 Starting date early 2026, with some flexibility. 🙏Please, RT!
- Finally after 5 years the first PhD from the lab! Congratulations Dr. Ake @franzake.bsky.social !!! 👏👏👏 🎉🎉🎉 It has been a pleasure to have you in the lab. #PhD_defense #new_PhD
- Reposted by Mireya PlassExcited and grateful to be part of this work with @smfernandezmoya.bsky.social and @mireyaplass.bsky.social at the Gene Regulation of Cell Identity lab!
- 🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells www.biorxiv.org/content/10.1...
- This project would have been impossible without the work of our collaborators Agnieskza Rybak-Wolf, @monikapiwecka.bsky.social & Alessandra Gioregtti.
- 🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells www.biorxiv.org/content/10.1...
- 🚨New preprint from the lab! This work led by @akshayjg.bsky.social & @smfernandezmoya.bsky.social shows how the RNA binding protein STAU2 regulates the timing of neurogenesis in iPSC-derived human cells www.biorxiv.org/content/10.1...
- Upon deletion of STAU2, we observe metabolic changes and accelerated differentiation of iPSCs
- Using single-cell transcriptomics, we have found that STAU2 alters mainly the transcriptomic profile of neuroepithelial cells
-
View full threadIf you wanna know all the details about the role of this interesting protein, please read the full pre-print on bioRxiv! #RBP #neurogenesis #iPSCs #scRNA-seq #STAU2
- #SENC2025 has just started. Looking forward to these 3 days showing the best neuroscience research in Spain.
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya Plass🧬🧬🧬 New review from the lab: Evolution of comparative transcriptomics: biological scales, phylogenetic spans, and modeling frameworks authors.elsevier.com/sd/article/S... By @mattezambon.bsky.social & @fedemantica.bsky.social, together with @jonnyfrazer.bsky.social & Mafalda Dias.
- Reposted by Mireya Plass[Not loaded yet]
- If you like our recent work and are interested in developing a postdoc project related to isoform diversity in individual cell types and their regulation, get in contact! We are looking for applicants for Marie Curie and EMBO postdoctoral fellowships #postdocposition #singlecell #RNA_processing
- Reposted by Mireya Plass🚨🚨🚨 Please RT! We're looking for a postdoc to join an exciting joint project between our lab @upf.edu & @crg.eu (Barcelona) and the Sander lab @mdc-berlin.bsky.social (Berlin) investigating how alternative splicing and microexons influences the maturation of pancreatic islets. Deadline: 30/09/25👇
- Reposted by Mireya PlassQuantification of transcript isoforms at the single-cell level using SCALPEL nature.com/articles/s41... by @miriplass.bsky.social and her team
- Reposted by Mireya PlassJoin our "Advances in Single-Cell Technologies" meeting in December in Freiburg, co-organised with Marco Prinz and @katrinkierdorf.bsky.social. Excellent line-up of speakers covering spatial technologies, lineage tracing, computational methods, and more. www.uniklinik-freiburg.de/single-cell-...
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya PlassTwo new preprints from the @arjunraj.bsky.social on #gastruloids. Both excellent. Exploring the relationship between macroscopic reproducibility v microscopic heterogeneity. Stunning experiments and much to think about biorxiv.org/content/earl... biorxiv.org/content/earl...
- Reposted by Mireya Plass[Not loaded yet]
- I’m really happy to present #SCALPEL, a new #Nextflow tool to quantify transcript isoforms at the single-cell level using conventional 3’ scRNA-seq data #scRNA-seq #single-cell #tools #isoforms www.nature.com/articles/s41...
- To do so, SCALPEL distributes the reads assigned to a gene to the different isoforms that the gene expresses in an individual cell
- These isoforms can be used to identify novel cell populations
-
View full thread#SCALPEL is the result of the work of @franzake.bsky.social with the support of @mschilli.com, Sandra M. Fernández-Moya, @akshayjg.bsky.social, Ana Gutiérrez-Franco & Lei Li. You can find #SCALPEL on Github here 👉 github.com/plasslab/SCA...
- Reposted by Mireya PlassI am very happy to have posted my first bioRxiv preprint. A long time in the making - and still adding a few final touches to it - but we're excited to finally have it out there in the wild: www.biorxiv.org/content/10.1... Read below for a few highlights...
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya PlassA major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)
- Applications are now open! We are recruiting 20 Assistant Professors in a wide range of subject areas. We're looking for early-career researchers with strong scientific merits and future potential. 🔗 All positions: ki.se/en/about-ki/...
- 🚨We are looking for post-doctoral candidates to apply for a MSCA fellowship. Projects on gene regulation in neural development or neurdegenerative diseases using single-cell omics. Computational & wet-lab candidates are welcomed! #postdoc #MSCA #Barcelona #singlecell.
- Requirements: -> less than 8 years of experience since PhD -> less than 12 months living in Spain Interested candidates please contact me by email. More info here 👉 marie-sklodowska-curie-actions.ec.europa.eu/actions/post...
- Reposted by Mireya Plass🚨 Our new preprint! In collaboration with @saramaciasrna.bsky.social and @heick.bsky.social labs 🧬 Control of retrotransposon-driven activation of the interferon response by the double-stranded RNA binding protein DGCR8 and its implications in 22q11.2 deletion syndrome. #22q11 #TEsky #RNAsky
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya PlassIn this Voices article, our @martingarridorc.bsky.social & @juliosaezrod.bsky.social discuss key strategies for building context-specific molecular networks: knowledge and data-driven methods, + future directions in the field bridging to structures and perturbations tinyurl.com/z8t6yych
- Reposted by Mireya PlassOur latest "Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data" A rigorous mathematical foundation for Waddington's landscape to study cell fate decision making Applied to ventral neural tube development www.biorxiv.org/content/10.1...
- Reposted by Mireya Plass[Not loaded yet]
- Reposted by Mireya PlassCheck out our latest work on the evolution of animal genome regulation out today in @nature.com. Nicely summarized below by @ianakim.bsky.social. www.nature.com/articles/s41... This is a major output from our ERC-StG project Evocellmap @erc.europa.eu at @crg.eu
- I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...
- The new website for the Plass Lab is up and running! www.plasslab.com thanks @imperio-sideral.bsky.social for such an awesome website!
- Reposted by Mireya Plass🚨Registration for the UK #EvoDevo meeting is open! Join us on July 11th in London to enjoy an exciting day of talks, posters, friends, and superb science! -Registration (only £5!): shorturl.at/9cQGL -More info: londonevodevo.ac.uk
- Looking for candidates for the FI STEP PhD fellowship. Deadline 31/03. Contact me if you are interested in joining the lab to develop your PhD project. agaur.gencat.cat/en/beques-i-...
- Please RT: We are still looking for computational and/or hybrid candidates to join the lab as PhD students. Topics on Alzheimer's Diseases, cell communication and aging. e-mail me if you are interested #joboffer #PhDposition #BCN #scRNAseq
- It was a pleasure to participate at the #EMBLRBP meeting and getting feedback together with @monikapiwecka.bsky.social from an awesome scientist like Narry Kim.
- Reposted by Mireya PlassI am glad to share that our study on RNA-protein interactions in the brain affected by myelin deficiency has been published in the latest Cell Reports issue. 😊🤠 Except for insights into RBPs, you will find there also something about circRNAs (of course!) :) www.cell.com/cell-reports...
- Great talk by @akshayjg.bsky.social at the #EMBLRBP conference on STAU2 rehulated GRNs on human neurogenesis
- amazing talk of tony hyman @ #EMBLRBP about RBPs and phase separation.
- back at EMBL for an exciting conference om RBPs! Looking forward to networking and discussind our work on AD and STAU2. #EMBLRBP #conferencemode
- Please RT: We are still looking for computational and/or hybrid candidates to join the lab as PhD students. Topics on Alzheimer's Diseases, cell communication and aging. e-mail me if you are interested #joboffer #PhDposition #BCN #scRNAseq
- Reposted by Mireya PlassWe are offering 15 PhD positions in Decoding Transcriptional Regulation in Regeneration by Advanced Genomics and Computational tools (funded by the DANIO-ReCODE MSCA 2023 Doctoral Network) 🇪🇸 🇭🇷 🇸🇮 🇬🇧 🇩🇪 🇦🇹 Apply now: euraxess.ec.europa.eu/jobs/290548
- Reposted by Mireya PlassJeff Bezos never wanted this cartoon to become public. He killed it, and as a result, pulitzer prize editorial cartoonist Ann Telnaes quit. Make sure everyone sees this cartoon.
- Reposted by Mireya Plass🚨🚨🚨 If you're a bioinformatician who loves: 🧬 #SingleCell #LongReadSequencing & #AlternativeSplicing 🚀 Collaborating and travelling Apply to work with us at the spectacular BIMSB (@mdc-berlin.bsky.social) in Berlin + @upf.edu-@crg.eu in Barcelona. Qs: www.transdevolab.com Please RT! 🙏
- Reposted by Mireya Plass#SpatialTranscriptomics is revolutionizing gene expression profiling at subcellular resolution! 🔬These 'molecular microscopes' can unlock disease mechanisms & guide therapies... But how to bring ST to the clinic? Our thoughts with T. Pentimalli and N. Rajewsky out @annualreviews.bsky.social 🧵👇
- Please RT: In my lab we are looking for computational #postdoc researchers to apply to a #juandelacierva or #embo postdoctoral fellowships to work on projects on post-transcriptional regulation on single-cell data (method development and/or data analysis). Contact me if you are interested!
- Still looking for #postdoc candidates to join our lab! Projects related to #RNA processing in #single-cell data and its role in cell type differentiation and neurodegeneration! #hybrid and #computational candidates from all nationalities are welcomed! #Barcelona #sciencejobs
- Reposted by Mireya PlassHuge effort from @anaconesa.bsky.social at @scb.iec.cat comparing long-read RNA technologies @pacbio.bsky.social @nanoporetech.com and softwares #sqanti3, #bambu, #talon, #isoquant, for isoform discovery, still challenging to disentangle real biology from artefacts
- for closing the day at the #XIIJornadesBioinformàticaiGenòmica from @scb.iec.cat we have Akshay presenting a poster about STAU2 function in neurogenesis.
- and now a talk by Franz Ake presenting SCALPEL, a pipeline for isoform quantification in single-cell data. #XIIJornadesBioinformàticaiGenòmica from @scb.iec.cat . #Nextflow #single-cell
- SCALPEL is available on GitHub! github.com/plasslab/SCA...
- SCALPEL work has been led by @franzake.bsky.social, an awesome PhD student in the lab
- first time scr4eam goes public! realistic & isoform-aware simulator of single-cell reads. short talk from @mschilli87.bsky.social at the #XIIJornadesBioinformaàticaiGenòmica #benchmarktools #scrna-seq
- You can find the github repo here 👉 github.com/plasslab/scr...
- The XIi jornada de bioinformàtica & genòmica from @scb.iec.cat starts now! #bioinformatics
- Reposted by Mireya PlassThis is so spot on. As a climate scientist and public intellectual, I see or experience these often
- Reposted by Mireya Plass..and to think that some people believe we can use these data to understand a cell www.cell.com/cell/fulltex... ......
- Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8
