Jaroslav Icha
Light microscopy at Bruker Fluorescence Microscopy division.
#lightsheet #multiphoton #superresolution #screening
Cell biologist in my previous life. Alumnus @mpicbg.bsky.social
@turkubioscience.bsky.social
- Deadline for abstract submission in one week! I'm sharing this reminder because right after the conference we have an open demo day at DZNE Bonn, which will include voltage imaging on Bruker 2P microscope and Ca imaging in freely moving mice with Inscopix miniscopes www.bruker.com/en/news-and-...
- We are hosting a demo day for @brukercorporation.bsky.social two photon microscopes and Inscopix miniscopes. 📅 March 26th 2026 📌 DZNE in Bonn Whole day event with hands on sessions, presentations and discussions with our existing 2P users. Register: www.bruker.com/en/news-and-...
- We (Bruker Fluorescence Microscopy) will run a satellite event on March 26th. A mixture of a hands on demo of our 2P and miniscopes and our user meeting. One can attend independently of the conference, so this is a free event for anyone who can make a daytrip to Bonn. www.bruker.com/en/news-and-...
- 💡 Join the 8th Bonn Brain Conference March 23–25, 2026 | DZNE Bonn, Germany Explore the latest in brain states, neural circuits, and behavior — with keynote talks by leading neuroscientists including Cori Bargmann and Edvard Moser @edvardmoser.bsky.social
- Reposted by Jaroslav IchaApplication is open! Come join us and our fantastic line-up of speakers next year in March in Bonn!
- Reposted by Jaroslav IchaJoin us for BonnBrain 2026! The official deadline for abstract submission is December 15th, but we only have a few slots left and might be sold out before the deadline. Apply quickly 👉 bonnbrain.de to be considered by our Scientific Committee!
- Reposted by Jaroslav Icha[Not loaded yet]
- First @brukercorporation.bsky.social (and mine) lightsheet microscope sale in Poland and it is straight away our most complex lattice system even with an IR laser photomanipulation module. Joint project with our distributor in Poland Labsoft.
- I meant to post it long time ago but things have been busy. Still, this article is worth sharing even if not breaking news. Researchers at Tsinghua University developed a new approach to tissue clearing, VIVIT, using among other instruments, the Bruker MuVi SPIM www.sciencedirect.com/science/arti...
- Reposted by Jaroslav IchaDevelopment of the zebrafish retina captured on a light sheet microscope. Credit to @ichajaroslav.bsky.social. #ZebrafishZunday 🧪
- Are you interested in long time lapse imaging of organoids? In this example, retinal organoids were imaged in high throughput for 3 days. The aim was to collect sufficient data to be able to use machine learning for predicting organoid differentiation just from brightfield images.
- Reposted by Jaroslav Icha[Not loaded yet]
- For those at Seeing is Believing in Heidelberg right now, do join our workshop, which is about to start soon at 11:30! www.embl.org/about/info/c... Focus on organoid time lapse imaging, with high throughput options as well. #EESImaging
- Reposted by Jaroslav Icha🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- We have just installed a third HIVE server in Czechia. After Prague and Brno, we are adding Olomouc! www.bruker.com/de/products-... Researchers often get HIVE to handle data from Luxendo as well as other companies' light-sheet scopes but it is a rather universal solution for big data management.
- Reposted by Jaroslav IchaWe are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
- Reposted by Jaroslav Icha🚨 Final bits are falling into place for #UKZF2025 🎉 The organisers are buzzing with excitement and can’t wait to welcome the zebrafish community to Exeter & Exmouth TODAY 🐟✨
- Reposted by Jaroslav Icha[Not loaded yet]
- Happy to be at the #V4SDB 2025 developmental biology conference. Amazing quality of the talks and a beautiful venue in the High Tatras in Slovakia. @v4sdb.bsky.social v4sdb2025.img.cas.cz/programme/
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav IchaDresden researchers @paveltomancak.bsky.social @bruvellu.bsky.social, Carl Modes, @cuencam15.bsky.social & colleagues published in @nature.com that a tissue fold in fruit fly embryos buffers mechanical stresses & may have evolved in response to mechanical forces. www.mpi-cbg.de/news-outreac...
- Reposted by Jaroslav Icha#LISH25 was BIG.
- Reposted by Jaroslav IchaThe Company of Biologists Workshops 2027: Excited to share that our workshop concept, "Bridging Scales and Disciplines to Understand Robust Development”, has been selected! 🤩@giuliapaci.bsky.social and I are looking forward to organizing it. Stay tuned for details! @biologists.bsky.social
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Really nice thread about the infrared co-illumination to reduce photobleaching of GFP. I was aware of the Ludvíkova et al paper but didn’t realize that lightsheet is the main modality, which would benefit from it.
- Reposted by Jaroslav IchaHow many photons are in a GFP? — more than last year, and more than you thought. Here's a simple, cheap, and practical method to break a fundamental limit in fluorescence microscopy. But it only works in light sheet!
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav IchaWould your #cellbio research benefit from you attending a #Microscopy or #BioimageAnalysis training course? For grants of up to £1,000, check out our Microscopy Training Grants with @focalplane.bsky.social Next deadline: 5 September 2025 www.biologists.com/grants/jcs-f...
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- We have just installed the high throughput microscope Acquifer IM from Bruker in the lab of Prof. Buchtova in Brno, Inst. of Animal Physiology and Genetics. This microscope is a versatile widefield fluorescence microscope, which is suited for imaging larger samples like organoids or fish embryos.
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Post no. 2 on lightsheet microscopy in neuroscience. Imaging whole cleared brains This is probably the most obvious use of lightsheet but I want to highlight something specific, read on. First, why is lightsheet uniquely suited for imaging whole cleared brains?
- Reposted by Jaroslav Icha[Not loaded yet]
- Looking forward to the conference in Wroclaw! I'll be there with our distributor Labsoft to talk mainly about Bruker's multiphoton and lightsheet microscopes and their applications in neuroscience.
- If you want to run a (drug) screen on something bigger than just 2D cells - like zebrafish embryos or organoids, we have a perfect instrument for you, the Acquifer IM. My colleagues summarized this into a new app note. Take a look: www.bruker.com/en/products-...
- Reposted by Jaroslav Icha🥂This was the highlight of my year. The "instigators", led by local master of the ceremony @svobodalab.bsky.social will never forget the privilege of organizing it and i think every participant will treasure the experience forever ❤️ @nature.com @josiegz.bsky.social www.nature.com/articles/d41...
- I’ve decided to do a few posts throughout the summer about using lightsheet microscopy in neuroscience, as part of my own learning. Today: calcium imaging Lightsheet with its widefield detection can be really fast and gentle to the sample, enabling 100s of frames per second imaging.
- Reposted by Jaroslav Icha
- Reposted by Jaroslav Icha🐌💫 Snail embryos never looked so fabulous! Tubulin (white), phospho-histone H3 (pink), and F-Actin (cyan) light up this early stage like a cytoskeletal disco ball. Image from Clemens Cabernard & Adam von Barnau Sythoff 🪩🧬 #FluorescenceFriday
- A great study showing the power of the zebrafish model. Methodologically rich from RNAseq, CRISPR screen to live and expanded sample imaging. It shows that nowadays you don't have to only image what is happening in development but you can also get to the mechanistic details, all using zebrafish.
- Interested in cell migration yet bored of the canonical translocation modes? 😴 Don’t worry — we @nordenlab.bsky.social with @aiopticalbiolab.bsky.social have multipolar migration back in stock! No need to follow the other cells: extend long protrusions and roam more freely🪼 in the crowded brain.
- Reposted by Jaroslav IchaCheck out @jalehtimaki.bsky.social and @nordenlab.bsky.social super cool latest work! We always wondered how horizontal cells "know" where to go despite lacking attachments. Turns out they need guidance cues from two different cell types... horizontal cells are the most social cells in the eye!
- Interested in cell migration yet bored of the canonical translocation modes? 😴 Don’t worry — we @nordenlab.bsky.social with @aiopticalbiolab.bsky.social have multipolar migration back in stock! No need to follow the other cells: extend long protrusions and roam more freely🪼 in the crowded brain.
- Reposted by Jaroslav IchaInterested in cell migration yet bored of the canonical translocation modes? 😴 Don’t worry — we @nordenlab.bsky.social with @aiopticalbiolab.bsky.social have multipolar migration back in stock! No need to follow the other cells: extend long protrusions and roam more freely🪼 in the crowded brain.
- Reposted by Jaroslav Icha[Not loaded yet]
- Photomanipulation. Something available on most Bruker Fluorescence Microscopy microscopes. Multiphotons, Lightsheets, high throughput systems. Over the years we specialized in this and accumulated a lot of practical know-how.
- Reposted by Jaroslav IchaBrillouin microscopy showing strength in non-invasive, live-imaging applications! Studying fruit fly embryos during gastrulation as cells rapidly change shape @prevedel-lab.bsky.social @gomezjm-devmech.bsky.social @marialep.bsky.social characterised & mapped mechanical changes in 3D. rdcu.be/ev6ZX
- Reposted by Jaroslav IchaExcited to share our latest Review on three-photon microscopy in the neurosciences - out today in @natrevneuro.nature.com! Hopefully this will help spread this powerful deep-imaging technique even further. Access here: rdcu.be/er5SZ Thanks to all co-authors!
- Reposted by Jaroslav IchaPls spread the word! We have a postdoc position available in the Rocha Lab @mpi-muenster.bsky.social. Join our team to study mechanisms underlying robust organ development using zebrafish embryos and human organoids. mpi-muenster.mpg.de/career
- We are looking for a #Postdoc with a great interest in biological robustness to lead a project investigating the self-correction capabilities of the developing nervous system. Join us at the @rocha-lab.bsky.social Rocha lab @mpi-muenster.bsky.social! jobs.mpi-muenster.mpg.de/jobposting/0...
- Looking forward!
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha[Not loaded yet]
- Reposted by Jaroslav Icha🚨🚨🚨 Tol2kit announcement! We have rebuilt the wiki that was corrupted a few months ago! We’re in the process of also linking it to the original address. Please visit us here: tol2kitkwan.genetics.utah.edu Thank you for your patience!! #zebrafish #transgenesis #plasmids #sharing
- Reposted by Jaroslav IchaHello microscopy and imaging experts and enthusiasts! We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English). Please apply and/or repost! jobs.unige.ch/www/wd_porta...
- If you are interested in FCS, FLIM and related methods: Bruker Luxendo lightsheet microscopes can be equipped with these modalities. It is admittedly rather niche, but very powerful. We already have a lot of experience implementing it. Customer webinar about it⬇️ info.bns.bruker.com/2025-07-08-W...
- Reposted by Jaroslav IchaIn Prague on Monday? Join my night science workshop on the creative process in science: openness, improvising ideas, how a hypothesis can be a liability, AI for hypothesis generation, import/export of ideas, puzzle switching, the 2 languages, questions, contradictions & awe 🙏 @svobodalab.bsky.social
- Corentin Rousset now introducing Bruker's Vutara VXL microscope to the EMBO course in superresolution microscopy in Prague. Practicals to follow later today with the generous help of Dr. Christoph Spahn. We will try z-stack acquisitions, STORM PAINT and PALM on bacteria. Looking forward!
- Reposted by Jaroslav IchaMorphodynamics of human early brain organoid development @nature.com @akanksha-jain.bsky.social @graycamplab.bsky.social nature.com/articles/s41...
- Reposted by Jaroslav Icha[Not loaded yet]
