Jaakko Lehtimäki
Currently post-doc @CellMigrationLab, previously @NordenLab. PhD from @LabLappalainen. Fascinated by cells on the move, zebrafish and boulders.
- A final milestone of my Lisbon-era☀️ Such an interesting type of migration and I just love all those dynamic protrusions❤️. Compared to my bioRxiv thread bsky.app/profile/jale..., we have here more data especially on the attractive neurturin-Gfrα axis.
- Check out the tour de force by @jalehtimaki.bsky.social in its final form: www.sciencedirect.com/science/arti... . An elegant combination of transcriptomics, F0 screens and high end imaging unravels the cues that guide cells (here retinal horizontal cells) in an increasingly crowded tissue. #proudPI
- Reposted by Jaakko Lehtimäki🚨 We are hiring TWO postdocs to join the Cell Migration Lab (cellmig.org) 🇫🇮 as part of the new Centre of Excellence in Immune–Endothelial Interfaces (IMMENs). Join us to decode immune regulation & develop next-gen imaging tools! 🧪🔬 Details in thread 🧵👇 #ScienceSky #Postdoc #AcademicJobs Please RT🫶
- Reposted by Jaakko Lehtimäki🚨 Job Alert! 🚨 We have an opening at our Microscopy Core Facility in Turku 🇫🇮. If you love imaging 🔬 and helping scientists succeed, we want you! 👇 abo.rekrytointi.com/paikat/index... #Microscopy #ScienceJobs #CoreFacility #Imaging @turkubioscience.bsky.social
- Reposted by Jaakko LehtimäkiInterested in Zebrafish brain imaging? We released a 3D printed mold that's is super helpful for us. Check it out Customizable FDM-based zebrafish embryo mold for live imaging www.biorxiv.org/content/10.1... Work by Marcela and Jaakko in the lab
- Reposted by Jaakko LehtimäkiNow online! Zebrafish use spectral information to suppress the visual background
- Mind-boggling. Remember seeing older papers on playing music to cultured cell lines. Would love to see the reviewer responses on this one.
- "Here we show that heartbeat sound promotes structural and functional maturation of human cortical organoids with a physiological astrocyte-to-neuron ratio." 🤯 www.biorxiv.org/content/10.1...
- Reposted by Jaakko LehtimäkiEric Peterman @errricpeterman.bsky.social, Jeffrey Rasmussen @jraslab.bsky.social @uwbiology.bsky.social & colleagues discover that microtubules regulate tissue-level navigation in skin-resident macrophages. journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/...
- Reposted by Jaakko LehtimäkiAcademic authors, here's a peek into the black box of journal publishing from an journal editor if you can bear it:
- Reposted by Jaakko LehtimäkiCancer cells are notoriously plastic, but what triggers the changes in cell state? In our new Nature (@nature.com) paper, Miranda Hunter (@mrndhntr.bsky.social) found that mechanical pressure is a key to this switch. Check it out here: go.nature.com/47iwDm2
- Had thought to test this wild idea in the future but so cool to see Francesca Peri lab making it real: Xenografted human microglia in zebrafish, doing their job 😍https://www.biorxiv.org/content/10.1101/2025.08.27.672578v1.full.pdf
- Reposted by Jaakko Lehtimäki🐟 Zebrafish (Danio rerio): Clear as glass, zebrafish embryos let you watch organs form in real time. A powerhouse for studying organogenesis and regeneration, they’re also champions of transgenic expression of fluorescent proteins 🌈 image from Gopi Shah 🧪 #ModelMonday #DevBio
- Interested in cell migration yet bored of the canonical translocation modes? 😴 Don’t worry — we @nordenlab.bsky.social with @aiopticalbiolab.bsky.social have multipolar migration back in stock! No need to follow the other cells: extend long protrusions and roam more freely🪼 in the crowded brain.
- But how then to know where to go? A problem many developing neurons face, including the retinal horizontal cells (HCs), we studied. Neighboring cells as tracks? Removing 3/4 retinal cell types and HCs still navigate correctly. However, take out the 4th type (amacrine cells) and 💥 HCs are stuck.
- Reposted by Jaakko LehtimäkiAre you looking for a postdoc? I will be looking for 2-4 people after the summer to join the lab !! Do not hesitate to reach out and disseminate !!
- Skimming through biorxiv might improve your climbing? As a non-expert (climber and in this field), I was taught to climb the route mentally before physically. Movement coordination comes through repetitions as in any sport.🤔
- Reposted by Jaakko Lehtimäki[Not loaded yet]
