David Llères
CNRS researcher in Marcelo Nollmann's team at Centre de Biologie Structurale (CBS) in Montpellier, France. Microscopist interested in using advanced imaging techniques (Hi-M, FRET, etc) to study 3D genome organization, gene regulation and epigenetics.
- Reposted by David Llères'The Centre for Research in Cellular Biology of Montpellier (CRBM) is recruiting Junior/Senior Group Leaders to shape its research in the coming decade. The deadline for application is 31st of March 2026.' #sciencejobs focalplane.biologists.com/cell-biology...
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- Reposted by David LlèresBIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
- Reposted by David LlèresEn ce début d’automne 2025, le CNRS continue de mettre à l’honneur les #FemmesEnScience. Tandis que "La Science taille XX elles" lance sa 8e édition, CNRS Ingénierie inaugure avec "Ingénieuses" une nouvelle exposition itinérante. Et le 15/10 paraît "Les filles sont parfaites pour les sciences".
- Reposted by David LlèresReally excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication. www.biorxiv.org/content/10.1... A🧵👇
- Reposted by David Llères🚀 Our new paper is out @natmethods.nature.com! Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells. 🔗 www.nature.com/articles/s41... 🧬 www.addgene.org/John_Ngo/
- Reposted by David LlèresFly labs — Now is the time to show some solidarity and chip in support for this vital resource!
- FlyBase needs your help! Visit the link below for more information, and please consider donating to help save this amazing resource. wiki.flybase.org/wiki/FlyBase...
- Reposted by David LlèresHow do enhancer-gene contacts relate to transcription activation? In mouse embryonic stem cells, a combo of STED, oligoFISH & RNA FISH shows that 3% of Dppa3 alleles transcribe. For these, enhancers and promoters come closer (panel E). Stumberger ... Leonhardt & Harz www.biorxiv.org/content/10.1...
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- Reposted by David LlèresYou can read about TurboCas here: www.sciencedirect.com/science/arti....
- Reposted by David LlèresHello World! Are you passionate about epigenomics and evolution 🧪🧬🐭🐵 ? Are you looking for a postdoc in a stimulating and inclusive environment ? Look no further... We are seeking creative postdocs for our ERC project EvoEpi @igred.fr ! 👇Details👇 tinyurl.com/PostdocEvoEp... Repost are appreciated
- Reposted by David LlèresCelebrating 10 years of our lab with a new preprint: www.biorxiv.org/content/10.1... How does enhancer location within a TAD control transcriptional bursts from a cognate promoter? Experiments by Jana Tünnermann and modelling by Gregory Roth
- Reposted by David Llères36 slots for selected talks from abstracts! Join us and share your latest research! Deadline for early registration coming up next week
- 📣Exciting meeting ahead! Join us next June in beautiful Cassis for #ShapingLife3! www.atoutcom.com/shaping-life/ @justinmcrocker.bsky.social @mhverlhac.bsky.social @guignardlab.bsky.social @bulutkarslioglu.bsky.social @dudinlab.bsky.social @flowerwhatelse.bsky.social @sfbd.bsky.social
- Reposted by David LlèresCome start your lab in beautiful Strasbourg 🇫🇷 www.nature.com/naturecareer...
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- Reposted by David LlèresThe U.S. Department of Defense is ending all of its funding for social science research, stopping 91 ongoing studies related to threats such as climate change, extremism, and disinformation. scim.ag/4hqu6HA
- Reposted by David LlèresOur study on how TAD boundaries actively influence the neighboring domains published today in @pnas.org: www.pnas.org/doi/10.1073/... Exciting outcomes from this interdisciplinary genomics/biophysical modeling strategy. See the thread for the BioRxiv preprint for a summary of highlights.
- Boundaries between TADs often extend over considerable distance. But how variable is this width of boundaries? And does it matter? Find out in our new pre-print with the group of David Holcman. www.biorxiv.org/content/10.1...
- Reposted by David Llères#Enhancer folks, submit your abstracts and register soon! Deadlines are around the corner and there are many opportunities for short talks.
- Reposted by David LlèresPaper out !!🥳big thanks to all authors @marliesoomen.bsky.social @diego-rt.bsky.social @kaessmannlab.bsky.social @jonathangoeke.bsky.social @lorenzamottes.bsky.social & 'bluesky-less' Lots of interesting new TE (& genes) biology Data fully browsable💻 👉 embryo.helmholtz-munich.de/shiny_embryo/
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- Reposted by David LlèresExcited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...
- Reposted by David LlèresL’Institut Pasteur décide de quitter X (ex-Twitter) pour rejoindre BlueSky ! 🦋 L’Institut Pasteur a pris cette décision en raison de plusieurs dérives graves constatées sur la plateforme X depuis son rachat. Rejoignez-nous pour continuer à défendre la science ! www.pasteur.fr/fr/espace-pr...
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- Reposted by David LlèresPortuguese Fly Meeting 7-8 November 2024, Batalha, Portugal. This is organized by Drosophilists working in Portugal but open to researchers from anywhere. Everyone, including Master students, is welcome to apply for oral or poster presentation. More info at: iridescent-gnu-ftqk0k.mystrikingly.com
- Reposted by David LlèresThe fruit fly Drosophila has been and continues to be a place where exciting new discoveries are made in all areas of biology. For example, we now have the entire "connectome" of its brain, with all neurons and neural connections identified. 1/n 🧪 www.science.org/doi/10.1126/...
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- Reposted by David Llères📢 We’re seeking a talented postdoc for Advanced Microscopy Fellows Program @harvardmed. Learn cutting-edge light microscopy techniques and more! microfellows.hms.harvard.edu/apply/
