Manuel Mendoza
Nuclear pore complexes and RNA export, Chromosomes and cytokinesis @igbmc.bsky.social Strasbourg. Who took the Bomp from the Bompalompalomp? Who took the Ram from the Ramalamading-dong? 🇻🇪 🇪🇸 🇫🇷
- Reposted by Manuel Mendoza🧬 #Yeast condensin does more than organize chromosomes. New study shows it acts as a transient crosslinker in entangled DNA, stabilizing entanglements rather than resolving them. This challenges current models of chromosome organizing proteins. #YeastResearch #SGD www.yeastgenome.org/reference/S1...
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- Reposted by Manuel MendozaPlease repost and consider applying: we work in such a fantastic context, we ask so interesting questions, and we have such a collegial and best-willing atmosphere… CRBM = Happy & Good Science
- Reposted by Manuel MendozaMelike Lakadamyali @melikel.bsky.social, Jérôme Solon and Manuel Mendoza @longchrom.bsky.social share the behind the paper story of their research interrogating how chromosome compaction scales with cell size using a combination of live confocal microscopy and 3D STORM.
- Reposted by Manuel MendozaMitosis has a timing system. If chromosomes attach properly, cells divide on schedule and keep proliferating. If attachment is slow or incomplete, the delay is recorded — and daughter cells stop dividing. We explore this link in our new preprint. 🔗 www.biorxiv.org/content/10.6...
- Reposted by Manuel MendozaI wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good. Stay free
- Thanks to @focalplane.bsky.social for the invitation to highlight our recent @biophysj.bsky.social paper! With @melikel.bsky.social and Jérôme Solon, we combined super-resolution and live imaging to connect interphase chromatin organisation to mitotic chromosome compaction across cell sizes.
- Reposted by Manuel MendozaI’ll soon share a call for a postdoc at Institut Jacques Monod (Paris) on fundamental mechanisms of membrane traffic and protein/collagen secretion in health and disease. Please get in touch if interested.
- “A student joining a lab is often presented with a hypothesis to work on and may see science as a hypothesis-testing endeavor. Many young postdocs have been told that as a PhD student their job was to answer questions—now they have to discover their own unknown unknowns.”
- Reposted by Manuel MendozaComme promis, un texte où je persiste et signe : le film "Le mage du Kremlin" est dangereux, car il se met au service du pouvoir russe en diffusant une vision du pays exactement conforme à ce que le Kremlin veut nous faire penser. colinlebedev.fr/2026/01/22/h...
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- Reposted by Manuel MendozaThis photo was taken in 1911 using glass plate technology by Herbert Ponting who was part of Scott's Antarctic expedition, The composition and detail are exquisite with the band of white snow/ice creating a perfect frame around the two people and the ship in the distance Iconic imo
- Who’s behind this? The answer will not surprise you www.cidrap.umn.edu/childhood-va...
- This is nuts
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- Reposted by Manuel Mendoza0/10 🥳 our #exocyst paper out in @cp-cell.bsky.social, led by Marta, Sebas & @sasmeek.bsky.social in collab with @jonasries.bsky.social, @cmanzo.bsky.social & Castaño-Díez labs #Quantitative_Cell_Biology Continuum architecture dynamics of vesicle tethering in exocytosis www.cell.com/cell/fulltex...
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- Reposted by Manuel MendozaHappy to share that the our manuscript "Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth" is now finally out in its final form @natcomms.nature.com www.nature.com/articles/s41... Below a short🧵 with the key findings!
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- Reposted by Manuel MendozaThis is basically the view of the world that Plato sets out to refute in the Republic. One of the core questions asked therein is: why do powerful people think the mere fact of them exercising dominion makes it good for them to do so? Sure, you *can* get away with stuff if you're powerful - so what?
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- A las barricadas compañeros, a trabajar conjuntamente en una agenda de cooperación
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- My sophisticated take on this is that when Trump said he was going to “run Venezuela” he was, in fact, full of shit
- Party like it’s the 1970s
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- “Maduro is gone. It’s tempting to think that, without him, the regime will implode. But Maduro’s system was always a team effort; the kind of regime that could very well survive decapitation. And if it does, Venezuelans will get the worst of it.”
- Welcome to 2026, the year of the Putinisation of American foreign policy
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- Reposted by Manuel MendozaRead our new preprint where we uncover a hierarchy in human PIC assembly and establish a quantitative framework that connects factor exchange kinetics to the regulation of Pol II activity in living human cells. doi: doi.org/10.64898/202... By A. Oravecz and our collaborators @molinalab.bsky.social
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- Reposted by Manuel MendozaHappy holiday ❄️⛄🎅! Global protein synthesis rates can fluctuate dramatically as a function of food intake, infections, energy resources, etc. Wondering whether/how protein elimination routes adapt to these changes to maintain proteome homeostasis ? Find out here: www.cell.com/cell-systems....
- Reposted by Manuel MendozaIn case any other Early-career scientist is interested in the call, I am based in Italy and we work on Transcription Factors cooperativity and their activation domains, co-translational assembly, promoter architecture (human cells). Very open to ideas! #HFSP #EarlyCareer
- Attention scientists from all over the world🙃 The Call for Letters of Intent for #HFSPResearchGrants 2027 is now open! 🧪 Get your international & interdisciplinary team. It's time to put your bold research idea into practice! 🔗https://bit.ly/48VsGCG 📅 15 Dec 2025–26 Mar 2026 #sts #LifeSciences
- Reposted by Manuel MendozaThanks @jcellsci.bsky.social for this opportunity to contribute to your centenary collection with our take on the state of the field - 10 years after its modern reincarnation 🧪🌍 W/ @alebenoit.bsky.social @eelcotromer.bsky.social @fritzlaylin.bsky.social journals.biologists.com/jcs/article/...
- Reposted by Manuel MendozaMy lab is hiring a postdoc (ERC funded)! If you're interested, get in touch!
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- Reposted by Manuel MendozaYour periodic reminder that science is not done by a few selected "stars scientists". Science is done by hundred of thousands. Siloed money mean a few flashy discoveries and a lot of waste. Want to change things? Make funding accessible and stop funding calls with less than 2% success rate.
- · #AcademicSky · The European Research Council is launching €7m Plus Grants for ambitious, long‑term research — open to researchers at any career stage but limited to about 30 awards; current ERC grantees and applicants are ineligible, reports @clanicholson.bsky.social.
- Reposted by Manuel Mendoza🚨 PhD opportunity in Strasbourg! 🚨 We’re looking for a motivated PhD student to join the @haploteam within the IMCBio program (PhD-2026-17). 🔗 imcbio-phdprogram.unistra.fr Please spread the word or contact me if you’re interested!
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- Reposted by Manuel MendozaBLOOMBERG REPORTER: “If there’s nothing incriminating in the Epstein files why not…?” TRUMP: “Quiet. Quiet, Piggy.” 😕