See full post

Conlon Lab

bconlon.bsky.social

Followers · Following

Associate professor studying antibiotics and host-pathogen interactions at UNC Chapel Hill

Joined November 2024

Posts Replies Media Original posts Likes

Conlon Lab bconlon.bsky.social · Jan 14
Congratulations to MD-PhD student, Amanda Velez and all co-authors on our new PNAS paper describing how the innate immune protein calprotectin incapacitates autolysins, inducing tolerance to B-lactam antibiotics. A fun collaboration with Thomas Kehl-Fie. www.pnas.org/doi/10.1073/...
PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

pnas.org

View on Bluesky Show all post labels

Reposted by Conlon Lab
Steve Diggle digglelab.bsky.social · Nov 13, 2025
www.theguardian.com/society/2025...
Deaths linked to antibiotic-resistant superbugs rose 17% in England in 2024

Data also shows an average of nearly 400 newly reported cases of antibiotic-resistant infections a week last year

theguardian.com

View on Bluesky Show all post labels

Reposted by Conlon Lab
Carolyn Ibberson cbibberson.bsky.social · Oct 24, 2025
Come join us in Knoxville! The Dept. of Microbiology 🧫🦠 at the University of Tennessee is hiring 2 Assistant Professors (tenure track, 9-month appt.). Microbial Drivers of Chronic Disease: apply.interfolio.com/173153Quantitative Microbe-Plant-Environment Interactions: apply.interfolio.com/173345

View on Bluesky Download image (1)Download image (2)Show all post labels

Conlon Lab bconlon.bsky.social · Oct 10, 2025
Delighted to share our latest paper - A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics. Excellently led by Dr. Kuan-Yi Lu. We think it's a great proof-of-concept that altering immune cell behavior can make antibiotics work better www.nature.com/articles/s41...
A host-directed adjuvant sensitizes intracellular bacterial persisters to antibiotics - Nature Microbiology

The authors developed a screen to find compounds that modulate intracellular Staphylococcus aureus metabolism and discovered KL1, which sensitizes persisters to antibiotics by reversing host-induced tolerance.

nature.com

View on Bluesky Show all post labels

Conlon Lab bconlon.bsky.social · Sep 11, 2025
Looking to hire a postdoctoral associate to examine how antibiotics frequently fail in vivo and identifying new ways to make them work better. unc.peopleadmin.com/postings/306...
Post-Doc Research Associate - Conlon Lab

This Postdoctoral Research Associate will be involved with advanced independent biomedical research, including project development, experimental design and performance, data analysis, written progress...

unc.peopleadmin.com

View on Bluesky Show all post labels

Reposted by Conlon Lab
Jake Choby jakechoby.bsky.social · Jul 2, 2025
Excited to share the work with @dweisslab.bsky.social‬ and great collaborators on how gene amplification generates dynamic heteroresistance to new beta-lactams, like cefiderocol. We hope drug developers will consider heteroresistance during antibiotic development rdcu.be/euijW
Copy number flexibility facilitates heteroresistance to increasing antibiotic pressure and threatens the beta-lactam pipeline

Nature Communications - Choby et al. show that dynamic increases in the copy number of preexisting β-lactamase genes in heteroresistance enables resistance of continua of cellular...

rdcu.be

View on Bluesky Show all post labels

Reposted by Conlon Lab
wolfganglab wolfganglab.bsky.social · May 15, 2025
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
Eric Topol erictopol.bsky.social · Mar 26, 2025
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
Infectious Diseases infectiousdz.bsky.social · Mar 5, 2025
[Not loaded yet]

View on Bluesky Show all post labels

Conlon Lab bconlon.bsky.social · Mar 4, 2025
www.nih.gov/news-events/... Nice to see our recent paper highlighted in NIH - Research Matters newsletter
Diabetes boosts antibiotic resistance in mice

Researchers found that infectious bacteria in diabetic mice rapidly evolved resistance to antibiotics.

nih.gov

View on Bluesky Show all post labels

Reposted by Conlon Lab
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ nizet.bsky.social · Feb 14, 2025
[Not loaded yet]

View on Bluesky Show all post labels

Conlon Lab bconlon.bsky.social · Feb 13, 2025
Delighted to share our new study. A collaboration with the Thurlow lab. Antibiotic resistance rapidly emerges and thrives in diabetic mice. A worrying coming together of two major and growing health problems worldwide www.science.org/doi/10.1126/...
Diabetes potentiates the emergence and expansion of antibiotic resistance

Diabetic infections are a reservoir for the emergence and proliferation of antibiotic resistance in Staphylococcus aureus.

science.org

View on Bluesky Show all post labels

Reposted by Conlon Lab
Ivan Zanoni lozanzi.bsky.social · Jan 11, 2025
#WeekendRead! Ahn, Arthur &co show @CellHost&Microbe that pathogenic E. coli produce a metallophore that sequesters zinc in macrophages, stabilizing HIF1a & driving fibrosis in #IBD mouse models and Crohn Disease patients! www.sciencedirect.com/science/arti...
Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease

Inflammatory bowel disease (IBD)-associated fibrosis causes significant morbidity. Mechanisms are poorly understood but implicate the microbiota, espe…

sciencedirect.com

View on Bluesky Show all post labels

Reposted by Conlon Lab
Antimicrobial resistance #AMR antimicrobial.bsky.social · Jan 6, 2025
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ nizet.bsky.social · Dec 6, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
John Helmann johnhelmann.bsky.social · Nov 21, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
Jay Hinton jayhinton.bsky.social · Nov 20, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
bioRxiv Microbiology biorxiv-microbiol.bsky.social · Nov 20, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
Andreas Peschel andreaspeschel.bsky.social · Nov 18, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
joshcompton joshcompton.bsky.social · Nov 17, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
Matt Barber biobarber.bsky.social · Nov 17, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
Gregg Gonsalves gregggonsalves.bsky.social · Nov 16, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Conlon Lab bconlon.bsky.social · Nov 16, 2024
Congratulations Lauren! Great work!
- Andreas Bäumler abaumler.bsky.social · Nov 15, 2024
  [Not loaded yet]
View on Bluesky Show all post labels

Reposted by Conlon Lab
Matthew Lawrenz lawrenzlab.bsky.social · Nov 9, 2024
[Not loaded yet]

View on Bluesky Show all post labels

Reposted by Conlon Lab
Victor J. Torres handle.invalid · Nov 15, 2024
[Not loaded yet]

View on Bluesky Show all post labels

An unhandled error has occurred. Reload 🗙