Zechner Lab
Research group at SISSA / Trieste. Interested in stochastic processes in biology & biophysics. Posts by C. Zechner.
- Reposted by Zechner LabThe EMBO Young Investigator Network consists of young investigators, installation grantees and global investigators. 🧪 Find more information on the individual programmes here: embo.org/the-embo-communitie… #LifeSciences #research #funding
- Reposted by Zechner LabExcited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
- Reposted by Zechner LabSee this recent paper by @andersshansen.bsky.social that discovers similar microcompartmentalization during mitotic exit: www.nature.com/articles/s41...
- Reposted by Zechner LabAn incredible ICTP initiative is our Postgraduate Diploma Programme. Rigorous one-year pre-PhD training for students from the Global South. I have personally seen this program transform the lives of those in the quant life sciences. Due Feb. 28 2026. Please share widely. www.ictp.it/news/2025/11...
- Reposted by Zechner LabSince more than a decade, our group has been exploring chemically active droplets, which are exciting since their size can be controlled. Yet, we still do not fully understand this control even in the simplest models. Until a new preprint (arxiv.org/abs/2512.02542) spearheaded by postdoc Guido...
- Reposted by Zechner LabWe are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28! www.cam.ac.uk/jobs/univers...
- Reposted by Zechner LabI am honored and proud to work with my amazing group @mpi-cbg.de and @csbdresden.bsky.social 🥰 🧬. Thanks to all my colleagues for the wonderful scientific environment. And thank you @kboes.bsky.social for preparing this superb video! 🤩
- Watch this video about the work of the research group of @agnestoth.bsky.social @mpi-cbg.de & @csbdresden.bsky.social. Agnes and her group work on protein plasticity and evolution. For her work, Agnes recently received the Schering Young Investigator Award 2025! youtu.be/lEpvGu3J63M?...
- Reposted by Zechner LabThe most precious commodity you have is your attention. You don’t have to waste it on poor-faith debates or arguments with strangers if you don’t think they’ll be productive. You can prioritize the things that matter to you and make your life richer.
- Reposted by Zechner LabI’m very excited to start this project — it brings together ideas that matured over many years and opens a long-term path for innovation in RNA modelling. 🍾 🧬
- 🎉Our group has been awarded a prestigious #FIS grant! #RNAScale - Exploring RNA Dynamics across Scales: From Base Pairs to Viral Genomes 👉 www.bussilab.org/fis3 We will soon open postdoctoral positions across several components of the project! An expression-of-interest form is already online.
- Reposted by Zechner LabOne of our founding directors Anthony Hyman @hymanlab.bsky.social will become @embl.org Director General: www.mpi-cbg.de/news-outreac...
- Anthony A. Hyman will become EMBL’s next Director General. He joins EMBL from @mpi-cbg.de in Dresden. He is also Professor of Molecular Biology @tudresden.bsky.social, and was a group leader at EMBL Heidelberg from 1993 to 1999. www.embl.org/news/people-...
- Reposted by Zechner LabWonderful to see the beautiful preprint from Sabate et al now published - TADs are also dynamic structures in human cells, with remarkably similar parameters between mESCs and HCT116 cells www.nature.com/articles/s41...
- Reposted by Zechner LabTwo 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176 #biophysics
- Reposted by Zechner LabReally excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication. www.biorxiv.org/content/10.1... A🧵👇
- Reposted by Zechner LabThanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.
- Hydra are ~basically~ immortal. Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads! This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
- Reposted by Zechner LabGreat work! Congratulations you all & especially to @carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
- The Friday second try: After intense work, especially in the last year, this work is finally ready to be seen by the public. Led by @apramos.bsky.social and great collaboration with @carldmodes.bsky.social group especially @liormoneta.bsky.social : www.biorxiv.org/content/10.1...
- Reposted by Zechner LabOut today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism. www.nature.com/articles/s41...
- Reposted by Zechner LabOur beautiful Hydra made the cover!!! 😍😍😍 An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de Actin fibers in blue, nuclei in orange.
- Reposted by Zechner LabOur first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.
- Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
- Reposted by Zechner LabStretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...
- Reposted by Zechner LabNovel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
- Reposted by Zechner LabWe are searching for an AI researcher in lab automation, statistical ML and (theoretical) physics AI for bio/med. Expression of interest and nominations welcome!!!
- Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
- Reposted by Zechner LabWe are looking for a research assistant to join our lab and support ongoing projects with genome engineering in mouse embryonic stem cells! Please get in touch if you are interested. www.fmi.ch/education-ca...
- Reposted by Zechner Lab(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint Q: how does chromatin move? Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
- Many congratulations to Anne for defending her PhD this week…excellent results and presentation! We wish you all the best for your future career!
- Reposted by Zechner LabWe are finalizing the program of the @cecamevents.bsky.social RNA modelling across scales www.cecam.org/workshop-det... at SISSA, Trieste, Italy, May 19-22. Please note that we still have a few slots for in person attendance. We will accept applications for the next few weeks, until fully booked!
- Still a few days remaining to apply for the RNA modelling across scales @cecamevents.bsky.social workshop at SISSA. Deadline March 23, hurry up!!
- Reposted by Zechner LabCome to #Prague for #Woodstock2025. What is it? A scientific conference unlike any other. Think #BurningMan or #MusicFestival but #science themed. It'll have two parts - decentralised sessions spread in #Prague (sightsee as you move around) & #campsite event to wrap it up (1/7)
- Reposted by Zechner Lab"Cacio e pepe" physics: In arxiv.org/abs/2501.00536v1, eight Italian scientists from the Max Planck Institute for the Physics of Complex Systems explain the physics behind a perfect dish of "cacio e pepe" and how to eschew the dreaded "mozzarella phase" - work featured @nytimes.com.
- Congratulations Tommaso for an excellent PhD defense! Very well done!
- Excited to share our new work with Frank Jülicher on noise control & concentration buffering in intracellular condensates! There has been confusion about these concepts, which we aim to address in this paper. www.cell.com/cell-systems...
- Key conclusions: 1. Noise reduction and concentration buffering are different concepts 2. Noise reduction does not depend on a fixed saturation concentration (c_sat)
- 3. Even "simple" systems with purely homotypic interactions lack a fixed c_sat in non-equilibrium conditions (e.g., cells) 4. Inferring solute interactions (homotypic vs. heterotypic) from changes of c_sat / partition coefficient is problematic in cells because of point 3.
- Reposted by Zechner LabStarting the new season of seminars in Molecular and Statistical Biophysics at SISSA! Gareth Tribello today gave a talk with title “Reconnaissance Metadynamics Rides Again”
- Please share! There are two postdoc opportunities at the Molecular and Statistical Biophysics group at SISSA. Join us in beautiful Trieste! More information at msb.sissa.it/join-us/
- Reposted by Zechner LabExcited to share James Jusuf's preprint: By integrating Micro-C with SuperRes Live-Imaging we can calibrate genomics&imaging to perform absolute quantification of looping (e.g. this loop is present 3%) We quantify mESC 36k loops: <loops> are generally rare (2.3%) www.biorxiv.org/content/10.1...
- Reposted by Zechner Lab📢 Post-doc opportunity alert! Join the Molecular and Statistical Biophysics group at SISSA. Choose your mentor from Giovanni Bussi, Cristian Micheletti, or Angelo Rosa, or collaborate across these groups. www.bussilab.org/joinus#postd... #joinus Please reshare!
