Luca Jovine
Professor of #StructuralBiology @karolinskainst.bsky.social studying #egg-#sperm interaction at #fertilization & #ZonaPellucida (ZP) module proteins
Member of #EMBO & the #NobelAssembly at Karolinska Institutet
More @ http://jovinelab.org
- The bureaucracy of science has grown so much, the system is collapsing upon itself: Scientists have become administrators of grants rather than spending time on science. Paid administrators are demanding even more administrative work from scientists. Administrators are eating the science budget.
- Very excited about this new preprint, in which @juliacoronasserna.bsky.social shows how cells ensure that fusion with another cell is irreversible! www.biorxiv.org/content/10.6... @biology-unige.bsky.social 👇
- 📢 Happy to share our new preprint from @sophiemartinlab.bsky.social ! Check our latest work on cell–cell fusion, uncovering how PAK kinases promote cell-cell fusion irreversibility by preventing cell wall repair.
- Mark your calendars for 2027! The best GRC is coming to Europe 🇳🇱 💥 Fertilization and Activation of Development 📍 Noordwijk, Netherlands 🗓️ July 31 - August 6, 2027 www.grc.org/fertilizatio... Can’t wait!
- Thrilled to announce that the GRC Fertilization and Activation of Development and associated GRS will come to Europe for the first time in 2027! Join us in Noordwijk, the Netherlands, 31 July–6 August 2027. Mark your calendars and help us spread the word! #GRC #GRS #Fertilization #Development
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- #aECM Cub starts next week Nov 18 with talks on patterning the Drosophila lens, mouse tectorial membrane, and C.elegans cuticle furrows. You can still sign up for access using the link below.
- The 2025-2026 #aECM club schedule is now posted on our website, where you can also find the link to sign up for access. I’m looking forward to lots of great talks and discussions! sundaramlab.com/blog/aecm-cl...
- OpenFold3-preview (OF3p) is out: a sneak peek of our AF3-based structure prediction model. Our aim for OF3 is full AF3-parity for every modality. We now believe we have a clear path towards this goal and are releasing OF3p to enable building in the OF3 ecosystem. More👇
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- 🧪 From petri dish to embryo model: @jacob-hanna.bsky.social work shows how naïve pluripotent stem cells can self-organize into advanced developmental stages. The 2025 #HFSPNakasoneAward lecture reveals the science behind synthetic embryo models. Full lecture 🎥 👉 zurl.co/Tgf4f #sts
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- This is a great meeting with great people and great science! Thanks again @jovinelab.org and @Rafael Fissore for the invitation!
- Excited that the Gordon Research Conference on Fertilization and Activation of Development 2025 (and associated GRS) is just a few days away! www.grc.org/fertilizatio... www.grc.org/fertilizatio... #GRC #GRS #fertilization #development #egg #sperm
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- Breaking News from @theathletic.bsky.social: Jannik Sinner defeated Carlos Alcaraz in a 4-set duel to win his first Wimbledon title.
- Molecular cat tweezers? 😺
- A paper thar took too long to finish. We show that AlphaFold3 its clearly better than AlphaFold2 (and Boltz-1 and Chai-1) to predict the structure of antibody-Antigens, but only for cases with (har to detect) similarity in the training set. www.biorxiv.org/content/10.1...
- Proud to share our work where we resolved a longstanding question regarding the existence of a human telomerase dimer and provided insights into its function. Led by 3 amazing lab members in collaboration with @yiliangding.bsky.social and @rdaslab.bsky.social. www.science.org/doi/10.1126/...
- Highly collaborative efforts that involved 6 lab members and the labs of @yiliangding.bsky.social and @rdaslab.bsky.social. We uncovered a telomerase dimer and its potential role in telomere maintenance.
- Sebastian Balch, Zala Sekne & Elsa Franco-Echevarría in @kellythd-nguyen.bsky.social's group have confirmed the existence of dimeric telomerase and illustrated how it is key to telomere maintenance: www2.mrc-lmb.cam.ac.uk/first-struct... #LMBResearch @yiliangding.bsky.social @rdaslab.bsky.social 🧪
- Professors Martin Jastroch, Hanna Johannesson and David Drew at Stockholm University are awarded Advanced Grants by the EU Research Council ERC @erc.europa.eu In total, it is about SEK 86 million for research in evolutionary biology, biochemistry and molecular bioscience. www.su.se/english/news...
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- Up on biorxiv! The tour de force protein tagging atlas for the #Celegans cuticle #aECM - from Jordan Ward @gotworms.bsky.social and Andrew Chisholm labs. So many beautiful images of cuticle collagen substructures !! www.biorxiv.org/content/10.1...
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- Happy 99th birthday to the man who gave voice to the wild. 🎉 Sir David Attenborough, thank you for a lifetime dedicated to the natural world, and for sharing its story with wisdom, wonder, and grace. You've inspired generations to fall in love with nature.
- We are very excited about our latest work, which just came out @embojournal.org – www.embopress.org/doi/full/10..... The work @MCB_UJ was driven by Anna Biela and Ting-Yu Lin 林亭妤 in collaboration with @jmbujnicki.bsky.social…a short🧵
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- I haven't seen the official announcement but would prefer to see more grants instead. I know it is not under the control of the ERC but I hope the EU manages instead to double the ERC budget. Take money away from the other research initiatives if needed.
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- A mammoth circus of macabre fantasy and moral bankruptcy. I got my views on mammoths down. Enjoy. www.theguardian.com/commentisfre...
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- Paper at Cell - ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat - zurl.co/xw7a - Our MiTeGen Loops zurl.co/Q3vm were used to help determine details of IVF-related mechanisms
