Julie Carnesecchi
Digging in RNA & TF interplay - Exploring TF-RNA networks in cell fate - Fly pusher + CNRS Researcher + Mentorfirst
igmm.cnrs.fr/en/team/integrative…
- Reposted by Julie CarnesecchiRegistration will open soon for the next JEDI meeting: June 1st - 3rd in Palmela, Portugal! Join us and our keynote speaker Eugenia Chiappe. Her #neuroscience lab studies how #Drosophila estimates its own movement and integrates sensory inputs to control locomotion. chiappelab.org
- Reposted by Julie CarnesecchiI am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
- Evolutionary dynamics of temporal transcription factor series in the insect optic lobe biorxiv.org/content/10.64898/20…
- Reposted by Julie CarnesecchiDear #Drosophila researchers, the year starts with good news! The date and venue for our next meeting is confirmed: June 1st to 3rd at the beautiful Historic Hotel Castle De Palmela in Portugal! Mark the dates, registration will open soon!
- Reposted by Julie CarnesecchiA new community-driven lab handbook for reducing conflict and creating more positive and equitable work environments gets strong support from a survey of 200 researchers. buff.ly/K7CGFLV
- Yesterday at @igmm-montpel.bsky.social we sold cakes &crêpes for @afm-telethon.bsky.social, all cooked and sold by volunteers. Proud to support research on neuromuscular disease, fundamental myology & gene therapy. Thanks, Florence Rage and everyone who contributed or came by! #Solidarity #Research
- Reposted by Julie CarnesecchiSo excited to finally be able to share my first paper and the culmination of my PhD work with @felipekteixeira.bsky.social 🪰🔬 www.pnas.org/doi/10.1073/...
- Reposted by Julie CarnesecchiWhen setting goals, we often focus on achieving milestones like a PhD, job, tenure, or promotion. Those are great goals but they’re not enough. We also need to think about: -Why we’re pursuing that goal -What specifically we need to do to succeed -The values we will follow as we do the work
- Reposted by Julie CarnesecchiDespair seems like a reasonable course of action 'Some estimates are that up to 20% of the entire proteome can bind RNA and moreover that about 20% of all known protein complexes have an RNA component in them and you really have to think about how to deal with such large figures.'
- Reposted by Julie CarnesecchiA reminder that the abundance of 'housekeeping' proteins varies significantly across cells and tissues. GAPDH is often slandered as a 'housekeeping' protein, and its abundance varies significantly across human tissues. How do you define a 'housekeeping' protein ?
- Reposted by Julie CarnesecchiHi folks, Check out our updated website! Details on next year's conference will be posted there soon! fly-jedi.org
- Reposted by Julie CarnesecchiCold induced #RNA binding protein linked with longevity and DNA repair
- The remarkably long lifespan of bowhead whales could be due to an increased ability to repair DNA mutations, according to research in Nature. go.nature.com/4hzvDN7 🌏 🧪
- Reposted by Julie CarnesecchiExcited to share my first PhD student’s @biorxivpreprint.bsky.social! Tracking 5 dyes simultaneously Kavan Gor @embl.org tracks nascent #RNA folding during #ribosome assembly to correlate structural with functional information on single RNA molecules! Check it out! www.biorxiv.org/content/10.1...
- Reposted by Julie CarnesecchiPreparations for the next JEDI meeting are underway! The upcoming Junior European #Drosophila Investigator / #NewPI meeting is planned for Portugal in June. Final dates and additional details will be announced soon - stay tuned for updates!
- Reposted by Julie CarnesecchiThis week in Science, researchers demonstrate positive affective contagion—a core component of empathy—in bumble bees. The discovery shows that even insects can share affective states, tracing the roots of affect and social cognition deep into evolution. Learn more: scim.ag/4oblMQq
- Reposted by Julie CarnesecchiThis article is a homecoming for me. As a PhD student, I focused on the growth-rate transcriptional regulation in yeast. Now, ~ 20 years later, we report protein regulation scaling with the growth rates of single cells in mammalian tissues. www.biorxiv.org/content/10.1...
- Reposted by Julie CarnesecchiA new family of ribosome hibernation factors in Archaea | bioRxiv biorxiv.org/content/10.1101/202…
- M2 internship (funded, 6months) in Montpellier — IGMM × ISEM with amazing @aigverte.bsky.social Project: Hox factors beyond DNA: how RNA binding links molecules to body-plan evolution. Start: early 2026 Apply: CV+motivation #Master2 #Internship #Montpellier #RNA #Hox #EvoDevo #Drosophila #Bat
- @igmm-montpel.bsky.social @isemevol.bsky.social @umontpellier.bsky.social www.linkedin.com/posts/julie-...
- Reposted by Julie CarnesecchiHigh levels of Cas9 are toxic in sensory neurons. Reducing Cas9 levels with uORFs avoids toxicity and is compatible with efficient editing. From @thompsonpeerlab.bsky.social. Fly lines @vdrc-flies.bsky.social #CRISPR #Drosophila www.biorxiv.org/content/10.1...
- Reposted by Julie CarnesecchiThere's an update on the state of FlyBase on the FlyBase.org front page. You can contribute to FlyBase at this link wiki.flybase.org/wiki/FlyBase... We express enormous gratitude to the people, labs, groups, and foundations who have already helped us. #FlyBase #Drosophila
- Reposted by Julie CarnesecchiThat’s a wrap! We are done with #EDRC2025 and we look forward to seeing everyone again in 2027 for #EDRC2027 in Bonn!
- Reposted by Julie CarnesecchiUpdate from #EDRC2025! Four days of amazing talks and poster sessions and JEDIs have reconnected across geographical boundaries. Dinner was fun and we are looking forward to everyone at the next #Drosophila conference!
- Reposted by Julie Carnesecchi#edrc2025 European #drosophila Society meeting announces the 2029 meeting location : see you all in Szeged (and Bonn in 2027 of course)!
- Reposted by Julie CarnesecchiWe are on day 3 of #EDRC2025 continuing with excellent #Drosophila science
- Reposted by Julie CarnesecchiDear JEDIs, as we are self-organizing using the #EDRC as a nucleator we decided it is time for a JEDI database to boost our network! If you identify as a JEDI, please contact us here or send a mail to katja.rust@uni-marburg.de to be added to our database. #Drosophila @fly-eds.bsky.social
- Reposted by Julie CarnesecchiWelcome to the second day of #EDRC2025 starting with two great keynote lectures by Cassandra Extavour from Harvard University and Yulong Li from Peking University
- Reposted by Julie Carnesecchi3, 2, 1 and we are on!!! #EDRC2025 is starting! Welcome to our more than 740 participants from more than 40 countries! Thank you to all our sponsors!
- Reposted by Julie Carnesecchi
- Reposted by Julie CarnesecchiOnly a few hours left before our meeting starts! Are you travelling to #EDRC2025 now? Let us know by using the oficial #EDRC2025 hashtag!
- Reposted by Julie Carnesecchi🧬 NEW Starr-Luxton Lab PREPRINT: Our 🌠grad student @XiangyiDing figured out why muscular dystrophy mutations cause such widespread cellular chaos. The answer wasn't what we expected - and it changes how we think about the disease. Thread🧵 (1/6). www.biorxiv.org/content/10.1...
- Reposted by Julie CarnesecchiDear JEDIs, the #EDRC meeting is coming soon! Who is joining? Looking forward to meeting everyone next week!
- Reposted by Julie CarnesecchiWe are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)
- Reposted by Julie CarnesecchiThe #Drosophila Dscam1 gene generates 10000s of isoforms, but only a small fraction supports neuronal functions. This study shows that #fitness & #immunity are the likely primary evolutionary drivers of Dscam1 isoform diversity in #arthropods @plosbiology.org 🧪 plos.io/4gp8cWd
- Reposted by Julie CarnesecchiOur new preprint is out ! We uncover how adult Drosophila muscles respond to injury through a coordinated dialogue between hemocytes, tracheal cells, and muscles. Check it out and please share @igdrennes.bsky.social
- Hello #Drosophila & #insect people! I am searching for libraries of ORF/RNA from Tribolium castaneum and Bombyx mori for cloning cDNA/proteins (or insects with unusual body plans). Is there an existing resource centre where I can find them, please? Thanks very much in advance for your help!
- We are recruiting an enthusiastic engineer to work on the core project of our lab: identifying Hox protein-RNA networks in Drosophila @igmm-montpel.bsky.social Interested in BioID, UV-RIP and muscle development? Apply: emploi.cnrs.fr/Offres/CDD/U... Please share! #jobOffer #RNA #hox #Drosophila
- Reposted by Julie CarnesecchiDear president@harvard.edu, dear gaudet@mcb.harvard.edu, to learn more about the importance of #Drosophila and crucial role of @flybase.bsky.social, and how it gave rise to at least 9 Nobel laureates in Physiology and Medicine, please see this link: droso4schools.wordpress.com/why-fly/
- Reposted by Julie CarnesecchiA time-resolved framework for the recruitment of mRNP processing and assembly factors to a site of transcription. Great work by the Montpetit lab! #RNAbiology #RNAprocessing #mRNP doi.org/10.1093/nar/...
- French only: article vulgarisé de nos premiers travaux d'équipe @igmm-montpel.bsky.social @wxiang007c.bsky.social #RNA #Hox #muscle Merci pour votre soutien a notre recherche fondamentale 🙏 @afm-telethon.bsky.social @agencerecherche.bsky.social
- #ResultatScientifique🔎| Les facteurs Hox ne lisent pas seulement l’ADN : ils dialoguent aussi avec l’ARN ! 🧬 🤝 @cnrs.fr @cnrsoccitanieest.bsky.social @umontpellier.bsky.social ✍️ @jcarnesecchi.bsky.social 📕 @narjournal.bsky.social
- Reposted by Julie CarnesecchiDrosophila research without FlyBase would be untenable. Time for all labs who can afford it to step up.
- A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate. www.philanthropy.cam.ac.uk/give-to-camb...
- Reposted by Julie CarnesecchiThis preprint from Helen Sakharova is one of the coolest things to come out of my lab: “Protein language models reveal evolutionary constraints on synonymous codon choice.” Codon choice is a big puzzle in how information is encoded in genomes, and we have a new angle. www.biorxiv.org/content/10.1...
- Reposted by Julie CarnesecchiI’m thrilled to share a @biorxivpreprint for my postdoc work in the @PerrimonLab🎉. Together with our collaborators, we built a tissue-specific atlas of circulating secreted proteins in Drosophila 🧬🪰🧪🗺️. Thread below🧵 1/8 www.biorxiv.org/content/10.1...
- 🎉 Thrilled to share our new paper in @narjournal.bsky.social! We uncover how the Hox TF Ultrabithorax controls alternative splicing to shape muscle patterning and homeotic identity 🧬 @igmm-montpel.bsky.social 🔗 doi.org/10.1093/nar/...
- 🔥 Highlights: – Ubx-RNA binding is required for splicing – DNA and RNA binding can be uncoupled – But only together do they drive homeotic function #RNA #Splicing #TF #GeneRegulation #Hox #Development #Muscle #Drosophila #OpenAccess
- 🙌 Massive kudos to co-first authors Constanza Blanco, @wxiang007c.bsky.social and Pan Boumpas for their hard work! 🙏 Grateful for support from @afm-telethon.bsky.social #MSCActions @agencerecherche.bsky.social
- Reposted by Julie Carnesecchi📣 We are recruiting new group leaders in Innovative Biology! RNA biology Epigenetic regulation Cell cycle regulation Cancer, immunology Virology Application and information ⬇️ application.igmm.cnrs.fr @cnrsbiologie.bsky.social @cnrsoccitanieest.bsky.social @umontpellier.bsky.social
- Wrapping up the #RNAOccinatie workshop, great #RNA science, friends and #proudPI of @wxiang007c.bsky.social first presentation 🤓🥰 #Drosophila #Hox #muscle accepted paper coming soon 🥳 @igmm-montpel.bsky.social
- Reposted by Julie CarnesecchiWe want to thank everyone who attended this year's #Drosophila JEDI meeting at Château du Feÿ! Three days of amazing talks, great ideas and chat at the camp fire. We are looking forward to meeting everyone again at the next meeting!
- Reposted by Julie CarnesecchiJoin me, #Drosophila people! A broad group of National Institutes of Health (NIH) public servants have taken action with the "Bethesda Declaration" that targets the NIH and HHS Leadership. Join these courageous and committed professionals by adding your name now. actionnetwork.org/forms/add-na...
- Reposted by Julie CarnesecchiELAV mediates circular RNA biogenesis in neurons genesdev.cshlp.org/content/earl... #RNA #RNAsky #RNAbiology
- Reposted by Julie CarnesecchiThe #SEBD fully supports the request for emergency funding by the European #Drosophila genetics database and encourages its members to help this important database #FlyBase @flybase.bsky.social
- #Drosophila @flybase.bsky.social requires emergency funding: "As it stands, by the end of July, 2025, there will be no future updates to #FlyBase, and in the worst case scenario access to the website will also be lost". Please help if you can!
- Reposted by Julie CarnesecchiWe currently have a call for support that has gone out to European labs, to support FlyBase-UK. We are asking our colleagues from labs in the US and other countries to wait for a similar call to them that will go out in the near future, to support the US sites. We thank you for your patience.
- URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.
- Reposted by Julie CarnesecchiContext
- Reposted by Julie Carnesecchi#Drosophila @flybase.bsky.social requires emergency funding: "As it stands, by the end of July, 2025, there will be no future updates to #FlyBase, and in the worst case scenario access to the website will also be lost". Please help if you can!
- Reposted by Julie CarnesecchiReady?
- Reposted by Julie CarnesecchiThis is also a useful complement to the "pivot" paper getting attention this week "...science marches backward when the participants are unwilling to consider preexisting information, and a certain level of push-back is warranted when such behavior is combined with excessive self-promotion"
- Reposted by Julie Carnesecchi"Single-molecule multimodal timing of in vivo mRNA synthesis" a collaboration with Rippei Hayashi's lab, work led by AJ Sethi #RNA #pre-mRNA #splicing #RNAprocessing #m6A #polyadenylation www.biorxiv.org/content/10.1...
- Reposted by Julie CarnesecchiA split ALFA tag-nanobody system for protein localization and proximity proteomics in mycobacteria biorxiv.org/content/10.1101/202…
- Reposted by Julie CarnesecchiAdvice for a scientific career: "A writer either repeats or contradicts themselves" – Cioran.
- Reposted by Julie CarnesecchiProfiling transcriptome composition and dynamics within nuclear compartments using SLAM-RT&Tag
