Altegoerlab
Group leader at Heinrich-Heine University | Exploring different aspects of fungal interactions | Passionate about Structural Biology | altegoerlab.de
- Reposted by AltegoerlabWe Are very happy that our Paper was published. Thank to everyone involved pubs.acs.org/doi/10.1021/... @mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social
- Reposted by AltegoerlabHappy to announce that our review article on vesicle-coupled mRNA trafficking is now availalbe @mibinet.bsky.social #EMBOrnaLocalization link.springer.com/article/10.1...
- Reposted by Altegoerlab⚡️Fully funded #PhD position in my lab at Stockholm University / SciLifeLab! If you’re interested in #lichens, #symbiosis, fungal biology, or meta-omics, please apply. Deadline Feb 1. Read more here: su.varbi.com/en/what:job/...
- Reposted by AltegoerlabOne week left to apply for the PhD position in my group in Stockholm!
- ⚡️Fully funded #PhD position in my lab at Stockholm University / SciLifeLab! If you’re interested in #lichens, #symbiosis, fungal biology, or meta-omics, please apply. Deadline Feb 1. Read more here: su.varbi.com/en/what:job/...
- Reposted by AltegoerlabGreat opportunity to join the lab of @patrick-pausch.bsky.social ! www.linkedin.com/feed/update/...
- Reposted by AltegoerlabNew lab preprint - Delora Baptista tested AlphaFold 2 and 3 for the prediction of structures of host-pathogen interactions and then applied these to study convergence of binding and molecular mimicry in host-pathogen vs. host-host interactions. www.biorxiv.org/content/10.1...
- Reposted by AltegoerlabAncestral sequence reconstruction reveals CTP-dependent loading of the bacterial centromere-binding protein ParB as an ancient evolutionary feature Now published: tinyurl.com/4ddhwbb3 Thanks to the Hochberg and Bange labs for the great collaboration!
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- Reposted by AltegoerlabDear Plant ECRs, don't miss this wonderful opportunity!
- Reposted by AltegoerlabVery happy to See This Published!!!! Thanks for the collaboration link.springer.com/article/10.1...
- Reposted by Altegoerlab📢Postdoc position available!🧪🧫🧬 Our group is seeking a motivated researcher to investigate the molecular mechanisms driving host–endosymbiont interactions. Full details & application: karriere.hhu.de//index.php?a.... Please help us get the word out!
- Reposted by AltegoerlabSo structural biology is not dead after all 😋 Not a big surprise The title of this article is exactly in line with what I think. Same applies to LLMs for scientific writing.
- Reposted by Altegoerlab📣Interested in doing your PhD in Plant Sciences 🌱, Microbial Sciences 🦠 or Computational Biology 👩💻? @ceplas.bsky.social offers 10 fully funded PhD 🎓fellowships. Pls repost and forward to interested candidates holding BSc degree.
- ‼️Please RT: The CEPLAS Graduate School call for 2026 is now open! Detailed info on our website: bit.ly/4q19JWk @hhu.de @unicologne.bsky.social @mpipz.bsky.social @fz-juelich.de @leibnizipk.bsky.social @plantsciencedbg.bsky.social
- Reposted by Altegoerlab👉Excited to share our latest work @natmicrobiol.nature.com, revealing a decrease in cytoplasmic crowding during filamentous growth in the human fungal pathogen Candida albicans. Furthermore we found that inhibition of ribosome biogenesis can trigger filamentous growth in this pathogen rdcu.be/eT1Su
- Reposted by AltegoerlabNew call for PhD students to join CEPLAS
- Reposted by AltegoerlabThe first paper of my PhD is now available as a preprint! 🎉 Transposable elements (TEs) don't just jump within fungal genomes, they also move extensively between species. In this study, we screened over 1,300 fungal genomes and found a conservative estimate of 5,500+ horizontal transfer events.
- Reposted by Altegoerlab#Lichens form their complex thalli through a partnership involving at least a fungus and an alga. But can these living structures be rebuilt in vitro? For more than a century, people have tried. With @spribille.bsky.social we revisited 150 years of #lichen #resynthesis to ask: has anyone succeeded?
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- Reposted by Altegoerlab📣 Now announcing the journal publication 📄 of our work in @newphyt.bsky.social on how Verticillium undermines the plant's 🌱 "cry for help": terrific work by @antonkraege.bsky.social & @wolki95.bsky.social doi.org/10.1111/nph....
- Reposted by Altegoerlab📣 I’m excited to share two open positions in my lab @leibniz-hki.de. For this interdisciplinary project with @luziagyr.bsky.social, I’m seeking (1) an enthusiastic PhD student interested in fungal natural product research and genetic engineering, as well as (2) a technical assistant 👇🏻
- Reposted by AltegoerlabNow out in Science! Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle. In @vcushing.bsky.social's magnum opus, we use #cryoEM to figure out how the CDK-activating kinase recognises CDKs to fully activate them - a key step in cell cycle control. www.science.org/doi/10.1126/...
- Reposted by Altegoerlab📣 New @biorxiv-microbiol.bsky.social preprint, another joint-venture of @wolki95.bsky.social & @antonkraege.bsky.social, co-directed by @nicksnelders.bsky.social. Here’s a 🧵
- Reposted by Altegoerlab🚀 New preprint! We used a human cell-free translation screen (~28 000 compounds) to discover NT-2, a #Fusarium -derived #mycotoxin that blocks human ribosomes. #Cryo-EM at 1.72 Å reveals a link between chemical inhibition and ribosome dormancy. www.biorxiv.org/content/10.1...
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- Reposted by AltegoerlabNew PhD opportunity in my group @thesainsburylab.bsky.social through the BBSRC NRP DTP Programme - see details of host to apply below biodtp.norwichresearchpark.ac.uk/projects/van...
- Reposted by Altegoerlab1/13 Thankfully, both you and your plants have a lot of sophisticated ways to fight off invading pathogens. In our new preprint, we describe a new way in which animals and plants share a common strategy to ward off harmful bacteria. www.biorxiv.org/content/10.1...
- Reposted by AltegoerlabFRET sensor for SA developed. www.science.org/doi/10.1126/...
- Reposted by AltegoerlabFran @frangordilloc.bsky.social and I wrote this piece on one of our favorite topics: the evolutionary relevance of co-receptors for immune receptor transfer in #plants 🌱 #EvoMPMI #MPMI Check also the beautiful paper by Zhang et al. on the PRR STOMR and discover what happened to its co-receptor 😱
- Lost & found: Reconstituting PRR immune function through co-receptor transfer @isabelmonte.bsky.social highlights work revealing cross-species co-receptor transfer can overcome restricted taxonomic functionality in rice, pointing to strategies for crop protection www.cell.com/cell-host-mi...
- Reposted by AltegoerlabPlease RT: We have an opening for a junior group leader position in „Phage Biology & Biotechnology“. www.fz-juelich.de/de/karriere/... Interested candidates are encouraged to contact me via email for further details. @spp2330.bsky.social; @mibinet.bsky.social
- Reposted by AltegoerlabA bit late 🙃 but happy to share our recent findings on #cdiAMP signaling in controlling #cyanobacteria #diurnal rhythm in @cp-iscience.bsky.social www.cell.com/iscience/ful... #cdiAMP is involved in almost all cellular processes, explaining it's essentiality in #cyano @hhu.de @mibinet.bsky.social
- Reposted by AltegoerlabNew pre-print from our group showing remarkable synchrony of proliferative growth and regulated cell death during plant infection- each conidial cell has a different fate - by the rice blast fungus. Led by Alice Eseola with @osesmir.bsky.social Lauren Ryder @danmaclean.bsky.social and Martin Egan
- Synchronous spatio-temporal control of autophagy and organelle trafficking is necessary for appressorium-mediated plant infection by Magnaporthe oryzae biorxiv.org/content/10.1101/202…
- Reposted by AltegoerlabWe’re renewing our collaboration with Google DeepMind! We'll keep developing the AlphaFold Database to support protein science worldwide 🎉 To mark the moment we’ve synchronised the database with UniProtKB release 2025_03. www.ebi.ac.uk/about/news/t... 🖥️🧬 #AlphaFold @pdbeurope.bsky.social
- Reposted by AltegoerlabVery interesting work for maintaining synthetic microbial consortia www.nature.com/articles/s41... @mibinet.bsky.social
- Reposted by AltegoerlabIndependent research fellowships leading to tenured positions at the John Innes Centre. Repost = nice. Thank you very much!!!
- Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026. Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years. Find out more: www.jic.ac.uk/training-car...
- Reposted by AltegoerlabViral AlphaFold Database (VAD) is live in Science Advances ~27,000 predicted viral protein monomers & homodimers Conserved folds across bacteria, archaea & eukaryotic viruses New toxin–antitoxin system KreTA uncovered Vast “functional darkness” remains uncharted www.science.org/doi/10.1126/...
- Excited to share our latest work, spearheaded by @gabmrojas.bsky.social! GPCRs are central sensors in eukaryotes, but little is known about them in fungi. In Ustilago maydis, we now uncovered a host-dependent GPCR mechanism that promotes fungal infection. Gabriel nicely explains the full story👇
