Elena Kuzmin
Assistant Professor, Dep. Biology, Centre for Applied Synthetic Biology, Centre for Structural and Functional Genomics, School of Health, Concordia University | Adjunct Professor, Dep. Human Genetics, Goodman Cancer Institute, McGill University
- Reposted by Elena KuzminNow online! Hallmarks of cancer—Then and now, and beyond
- Reposted by Elena Kuzminhere is our first contribution of yeast in microbiomes led by Jason Tsai group[ with contributions from Alberto and Nelly: www.biorxiv.org/content/10.6... more to come
- Reposted by Elena KuzminCanada is launching a new funding program for PhD students and postdoctoral scientists. Reach out to me if you are interested in studying gene regulation, RNA splicing and/or cancer immunotherapy using computational and/or experimental approaches. #PhD #Postdoc
- Reposted by Elena Kuzmin❄️The 2026 Winter Session of GIIN Webinars is here! Join us on the first Tuesday of each month at 5 PM (Rome) / 11 AM (NYC). No pre-registration needed, simply join via Zoom: uniroma1.zoom.us/j/95149984403 Want reminders? Subscribe here: docs.google.com/forms/d/e/1F...
- Reposted by Elena KuzminCheckout the latest preprint from the lab - single-cell CIN signatures unlocked! Ongoing HRD improves PARPi sensitivity detection and ongoing NHEJ associates with subclonal diversification in TNBC
- 📢 New preprint out! We are thrilled to introduce our framework to track #ongoingCIN by leveraging single-cell genomics and CIN signatures: www.biorxiv.org/content/10.1...
- Reposted by Elena KuzminThank the @johndoench.bsky.social and Root labs for depositing these deliciously named libraries, and check out our blog post for more:
- Very excited to co-chair the 2026 Forbeck Forum on Evolution and Modeling of Cancer Genetic Networks and Cell States with @goyallab.bsky.social | Great line-up of speakers, intimate setting and thorough discussions! www.forbeckforums.org/forums/evolu...
- Reposted by Elena Kuzmin2026 #Yeast #Genetics Meeting is 13–17 June 2026 in Pacific Grove CA. Conference website has invited speakers, abstract submission topics, preliminary schedule, etc. Bookmark the site as additional updates will be published as they become available. #YEAST26 genetics-gsa.org/yeast-2026/
- Reposted by Elena KuzminPlease 🔁! #MASSIV will be held in Vancouver from January 19-22, 2026. 4-day meeting on #synbio x #tissueengineering. Some trainee-focused events. >50 talks (10 from abstracts), posters, panel & publishing insights sessions. www.massivconference.com Abstract deadline: Nov 14
- Our department is looking for a Canada Research Chair Tier 2 in Applied Synthetic Biology candidate! Deadline to apply is Dec 5, 2025. Please, repost. www.concordia.ca/jobs/artsci/...
- Reposted by Elena KuzminPlease RP! A 4-day synbio and tissue engineering conference #MASSIV to transform biology and medicine together. Couldn't list all amazing speakers, so please check out this 👉https://www.massivconference.com/ Poster due is Nov 7, but will be extended. With @stemcellnetwork.ca and JST.
- Reposted by Elena KuzminExcited to share my first first-author preprint! This work would not have been possible without the support and guidance of my supervisor Dr. Elena Kuzmin, as well as my lab mates (past and present) and our collaborators.
- Excited to share our preprint on the “Integrated Metabolic Complex Genetic Interaction Network of Chromosome 4p Loss in Basal Breast Cancer” led by @lynnkaram.bsky.social! www.biorxiv.org/content/10.1...
- Excited to share our preprint on the “Integrated Metabolic Complex Genetic Interaction Network of Chromosome 4p Loss in Basal Breast Cancer” led by @lynnkaram.bsky.social! www.biorxiv.org/content/10.1...
- 1️⃣ We used differential gene expression analysis of patient derived xenografts and cancer cell models to show that chr4p loss is associated with changes in cellular energetics.
- 2️⃣ We analyzed DepMap pooled genome-wide CRISPRCas9 screens and identified complex genetic interactions specific to chr4p deletion in basal breast cancer cell models.
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View full threadwith a great team of collaborators @traver.bsky.social @guilbourque.bsky.social
- Reposted by Elena KuzminIn #G3journal, @elena-kuzmin.bsky.social et al. present PARPAL database, a valuable resource for #yeast researchers to understand the retention and evolution of paralogs. A phenomics screen further shows how proteins respond to paralog deletion by localization & abundance changes. buff.ly/oM97WyH
- Our manuscript on the PARPAL database is out in G3! We share our phenomics screen on how proteins respond to their paralog deletion by localization & abundance changes and integrate other datasets with collab @guilbourque.bsky.social @leopoldparts.bsky.social doi.org/10.1093/g3jo...
- Reposted by Elena KuzminAt long last, Rosalind's paper on comparing methods for paralog synthetic lethality is online: genomebiology.biomedcentral.com/articles/10....
- Our manuscript on how single-cell imaging of protein dynamics of paralogs reveals sources of gene retention is out in iScience with a great team of collaborators @leopoldparts.bsky.social @guilbourque.bsky.social www.cell.com/iscience/ful...
- 1️⃣ We used high-content screening and deep neural network analysis to investigate how proteins respond to the deletion of their paralogs in yeast
- 2️⃣ We used protein abundance and localization changes to identify paralogs that show compensatory vs dependent responses to the deletion of their paralogs
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View full thread8️⃣ Why are we excited about this is because this is the first systematic investigation of relocalization changes of paralogs and provides insight into their retention in evolution
- Reposted by Elena KuzminPlease check out our new approach to modeling somatic mutation signatures. DAMUTA has independent Damage and Misrepair signatures whose activities are more interpretable and more predictive of DNA repair defects, than COSMIC SBS signatures 🧬🖥️🧪 www.biorxiv.org/content/10.1...
- Reposted by Elena KuzminJoin us for the 2025 SynBio7.0 conference in Toronto, June 1-3! SynBio is Canada's largest academic synthetic biology conference. More details on our website! synbio7.vercel.app
- Reposted by Elena KuzminLast call for a postdoc position in single cell analysis/perturb-seq with @nikashakiba.bsky.social at UBC in beautiful Vancouver Canada! ubc.wd10.myworkdayjobs.com/en-US/ubcfac...
- Reposted by Elena KuzminThe Early Bird Registration & Submission Deadline is approaching: March 28, 2025! 🔗 Register now premc.org/yeast2025/re... Don’t wait until the last minute, spots are limited and allocated on a first-come, first-served basis 🌟 the list of Outstanding Invited Speakers premc.org/yeast2025/in...
- Reposted by Elena KuzminJust add sorbitol! onlinelibrary.wiley.com/doi/full/10....
- Great study to have been involved in!
- Benchmarking macaque brain gene expression for horizontal and vertical translation | www.science.org/doi/10.1126/... How useful is macaque brain gene expression for asking questions about macaque protein abundance and human gene expression? Andrea Luppi explores ⤵️
- Very excited to share our preprint on the PARPAL web data portal capturing how proteins change their subcellular localization and abundance due to their paralog deletion w/ collab @leopoldparts.bsky.social @guilbourque.bsky.social www.biorxiv.org/content/10.1...
- Reposted by Elena KuzminSome science news to brighten up your timelines ☀️ Our latest work on the modifiers that cause changes in gene essentiality between genetic backgrounds, now on bioRxiv: www.biorxiv.org/content/10.1... So what did we find?
