Guillaume Bourque
Prof in Human Genetics at McGill, Director of Bioinformatics at the McGill Genome Center and Director of @C3Genomics
computationalgenomics.ca/BourqueLab/
- Reposted by Guillaume BourqueCrushed to hear of Mark Batzer’s passing. He was the Boyd Professor at Louisiana State University. His influential research revealed how mobile elements shape the genomes of humans & other mammals. Mark’s personality, generosity & positivity were larger than life. He lifted everyone up. HUGE loss 💔
- Nice Christmas gift to see it in print!
- Exciting new conference!
- Congrats Manvendra, well deserved!
- Reposted by Guillaume BourqueGA4GH April Connect 2026 registration and session proposal submissions are now open! The meeting will take place from 14 to 17 April 2026 in Montreal, Canada. We invite the GA4GH community to submit session proposals by 30 January. Learn more: broadinstitute.swoogo.com/connect26/10...
- Exciting! Glad to see the Gold Cohort starting to get used for new discoveries!
- 🧬 🌐 Uncovering cancer’s hidden driver mutations through the power of the Gold Cohort 🧬 🌐 A research team led by Dr. Ian Watson will harness the power of MOHCCN's Gold Cohort to identify new mutations that may be responsible for driving cancer. tinyurl.com/5n7c6ub8
- Reposted by Guillaume BourqueExcited to share our preprint on the “Integrated Metabolic Complex Genetic Interaction Network of Chromosome 4p Loss in Basal Breast Cancer” led by @lynnkaram.bsky.social! www.biorxiv.org/content/10.1...
- Such a great @ga4gh.org meeting in Uppsala this past week. Genomics, with the help of GA4GH standards and policies, is really moving into the Age of Implementation globally!
- If you’re planning to be at ASHG, you should go see the poster ⬇️
- Thanks for sharing our work, @guilbourque.bsky.social! This work will also be presented at the #ASHG2025 conference on Wednesday, October 15th, in Boston!! My poster can be found at Board 1100W at the Thomas M. Menino Convention Center. Come and talk to me 🧬!!
- Wow, great summary!
- Reposted by Guillaume BourqueThanks for sharing our work, @guilbourque.bsky.social! This work will also be presented at the #ASHG2025 conference on Wednesday, October 15th, in Boston!! My poster can be found at Board 1100W at the Thomas M. Menino Convention Center. Come and talk to me 🧬!!
- 🚨 New paper alert on telomeres! 🚨 Something different from the group! Thanks to Yuxin, a talented student in the lab, we used long-reads in 75 human trios to study telomeres and their inheritance.
- We were able to confirm that different chromosome arms have different length distribution, consistent with what was reported in Karimian et al 2024. We also observed the expected age-related length decrease.
- It got really interesting when we started to do allelic tracing since we had trio data. Amazing to be able to do it by eye in some cases and then @davidlougheed.bsky.social helped us build a tool called TeloScore to apply it to all the families we had.
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View full threadThis suggest that telomere maintenance in sperm is more robust than in oocytes and impacts the inherited telomeres. Full paper is below. Curious to know what you think as this is a new area for us! www.biorxiv.org/content/10.1...
- So inspiring to run with Darryl Fox to support Terry’s dream and the @marathonofhope.bsky.social
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- Excited for the start of the Croucher Retrotransposons meeting organized by Danny Leung in Hong Kong. First speaker, the King of Krabs! projects.croucher.org.hk/advanced-stu...
- The issue that jumped at us in the current annotation of young LTR subfamilies in human, is that there was lot of variability in divergence rate (sometimes bimodal). That's what we tried to improve.
- Is the annotation of viruses in the human genome accurate? We think not. Take a look at our new paper and let us know if you agree! www.science.org/doi/10.1126/...
- Is the annotation of viruses in the human genome accurate? We think not. Take a look at our new paper and let us know if you agree! www.science.org/doi/10.1126/...
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- Reposted by Guillaume BourqueExcellent opportunity for PI positions at the Genome Institute of Singapore! Outstanding facilities, latest genomic technologies, strong and stable science funding. Junior candidates and established scientists are welcome to apply
- Are you passionate about advancing scientific research?🧬🔬 🧪 We are #hiring Principal Investigators who are ready to make a difference in the world of genomic research in AI, Computational biology to develop novel high throughput technologies for unveiling new insights into the biology of DNA or RNA!
- Bye bye magical Kyoto, see you next time!
- Check out the new STR tool from @davidlougheed.bsky.social in the group! Works with both PacBio and Nanopore!
- Yeah, great one!
- Reposted by Guillaume BourqueOn January 6th, 1995, my (now ex) wife and I boarded a flight from Heathrow to JFK on a one way ticket. We had two suitcases and about $900 in cash - this was everything we owned and we were moving to the US. We thought it was maybe for 2-3 years. I had visited the US once, for a conference, and
- Reposted by Guillaume BourqueWe are recruiting! We have an open position for a postdoctoral fellow to join our team at the Genome Institute of Singapore to work with long read RNA-Seq data. It’s a beautiful city state and outstanding research environment! More details here: jglab.org/postdoc-posi...
- Amazing! So moving. Such an important cause.
- Time for #MadeInCanada! madeinca.ca
- Thanks for sharing this very nice story of collaboration!
- Reposted by Guillaume BourqueDear all, registrations are open for the Mobile Genome @EMBO workshop. Many slots for posters, short talks but also long talks for last minute groundbreaking results! Let’s meet again on Nov 4-7, 2025 in Heidelberg. www.embl.org/about/info/c...
- Back in Barbados!
- Congratulations to the newly minted Dr. Zhuang! Well done! His thesis was about: "Unveiling Sex-Biased Patterns in RNA Expression and DNA Methylation in Mice Organs".
- If you're interested about this you can look at: pmc.ncbi.nlm.nih.gov/articles/PMC... and also: www.biorxiv.org/content/10.1... With another paper to come.
- Big thanks to Prof Anna Namouva, for countless hours providing guidance on these truly collaborative projects.
- We also explore the contribution of transposable elements in this work of course! #TEsky
- Two months ago, Jeffrey from lab also became Dr. Hyacinthe! His thesis was: "An Atlas of Transposable Elements Associated with the Epigenome Across Human Cell Types"
- You can get a taste for his work on #TEsky in this preprint: www.biorxiv.org/content/10.1...
- Important to support data infrastructures! I signed!
- Absolutely! Thanks again for doing most of the planning work.
- Reposted by Guillaume Bourque« Tout est public sur Bluesky? Les gens vont me piquer mes trucs! » 🧵 Un petit fil sur les avantages et les défis d’un réseau social où nos données sont publiques et faciles d’accès.* * Informé par plus d’un millier d’heures passées à jouer dans le code de Bluesky. 👇
- Wow, that’s quite a poster session #MBSJ2024! And it’s only half of it…
- Reposted by Guillaume BourqueLong-read special issue of GR is out, including our paper on T2T assembly using only Nanopore. Just in time for ONT to discontinue duplex cells on Nov 27 😅😂 Good thing Verkko also works great with HERRO-corrected simplex data! 📄 genome.cshlp.org/content/34/1... 📖 genome.cshlp.org/content/34/1...
- I will be at my first large Japanese conference next week (MBSJ in Fukuoka). I'm organizing a session on computational epigenomic methods with Ryuichiro Nakato. Let me know if you're also planning to be there! www.aeplan.jp/mbsj2024/en-...
- Reposted by Guillaume BourqueTracking transposable element (TE) activity in genomics data can be a pain, but there are solutions! Our lab built TEtranscripts -- which we've updated to work for small RNAs (TEsmall), bulk RNA at the locus level (TElocal), and in single-cell data (TEsingle). Check it out! www.mghlab.org/software
- Reposted by Guillaume BourqueIf you like #Transposons 👾 check out this feed and tag your posts with #TEsky! Thanks @tobybarilbio.bsky.social 🤗 bsky.app/profile/did:...
- Looking for postdoc for the lab in Kyoto 🇯🇵 to work on comparative epigenomics and transposable elements. #TEsky Come work with us in this awesome city and institute! ashbi.kyoto-u.ac.jp/wp/wp-conten...
