Claire O'Callaghan
Working in neuroscience etc.
Sydney, Australia
- Reposted by Claire O'CallaghanExcited to share newly minted PhD Anu Korukonda's tour de force thesis work describing the impact of pathogenic tau on #locuscoeruleus function in a mouse model of early #Alzheimers. A must for #BlueSpot researchers! www.biorxiv.org/content/10.6... 1/3
- Reposted by Claire O'CallaghanNow in press one of my last PhD projects! We traced the neurobiological profile of fMRI BOLD signal variability, a measure that has been related to age, behaviour, disease status, but had not yet been fully contextualised within the brain's multiscale architecture. www.nature.com/articles/s41...
- Reposted by Claire O'CallaghanOur latest preprint on how regional cellular, molecular, and other forms of heterogeneity shape macroscopic wave dynamics is now out: www.biorxiv.org/content/10.6... For a full thread, see: x.com/_victorbarne...
- Reposted by Claire O'CallaghanThe extended version of my thesis procrastination project/subcortex visualization package is out now in both Python and R, now that I’ve graduated 🤠 This figure shows the 9 atlases included (and counting)! Preprint: www.biorxiv.org/content/10.6... Website: anniegbryant.github.io/subcortex_vi...
- Reposted by Claire O'CallaghanWhy do some worms graze on bacteria while others hunt and kill? Our study, published today in Nature, reveals how predatory aggression evolved in nematodes. Led by @gunizgozeeren.bsky.social and @leoboeger.bsky.social across the @jameslightfoot.bsky.social and @monikakscholz.bsky.social labs.
- Reposted by Claire O'CallaghanExcited to share our new preprint! We explore the link between the locus coeruleus (LC) and arousal for astrocytes, pyramidal cells, interneurons in the hippocampus. A fantastic collaboration with @sianduss.bsky.social @bohaceklab.bsky.social, and many others: www.biorxiv.org/content/10.6... 1/5
- Reposted by Claire O'CallaghanWhat is the computational role of dendritic excitations? Byung Hun Lee and team mapped voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons in mice navigating in virtual reality. www.biorxiv.org/content/10.6...
- Reposted by Claire O'CallaghanA major part of our future health & prosperity lies in medical research. There are billions of available dollars that can be used for vital medical science. Please join the campaign for our government to act urgently to fully disperse these funds: aamri.org.au/mrff/ www.theage.com.au/politics/fed...
- Reposted by Claire O'CallaghanThrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...
- Reposted by Claire O'CallaghanExciting announcement! Our Institute is calling for applications for a EMCR 2-year fellowship . Come and join a great team @turnerinstitute! Details here: careers.pageuppeople.com/513/ci/en/jo...
- Reposted by Claire O'CallaghanMy very normal, by the book presentation from this years OHBM is now available. So if you weren't at OHBM, were there but happened to miss it, or if you did see it and just want to relive it all over again, here is your chance :) I'm quite fond of this one. www.youtube.com/watch?v=lP86...
- Excellent read for a clear take on the current state of Australian scientific research funding
- Reposted by Claire O'Callaghan
- Reposted by Claire O'CallaghanWe used rabies virus 👾 to map how #psilocybin modifies long-range circuits 🧠, revealing network-specific reorganization that we didn’t expect. The full study is now online at Cell. @cp-cell.bsky.social Paper 👉 www.cell.com/cell/fulltex... Thread for a synopsis 👉 bsky.app/profile/alex...
- New preprint + thread 🧵 #Psychedelics induce the formation of new synapses, but where do they connect? Our rabies tracing study reveals that #psilocybin shifts connectivity across specific cortical networks. www.biorxiv.org/content/10.1... 1/12
- Reposted by Claire O'CallaghanVery important! If you are an Australian researcher, please complete
- Every opportunity politicians provide for you to tell them about how chronic underfunding of research in Australia is affecting your particular fields, people, working conditions etc. is extremely important. Fill out the form here: lnkd.in/g8A_PAZG
- Reposted by Claire O'CallaghanAmazing letter in The Times (also an unbelievable play fwiw)
- Reposted by Claire O'Callaghan🔥🔥The Program for the 2026 Noosa Brain Workshop is now Available!!! 🔥🔥 We have an incredible line up of confirmed speakers! Commuter registrations are still available, but places are limited. Check the website for details: www.monash.edu/turner-insti...
- Reposted by Claire O'CallaghanRapid neocortical network modifications via dendritic plateau potential induced plasticity biorxiv.org/content/10.1101/202…
- Reposted by Claire O'Callaghan🚀 We're hiring ! 🕵️ Seeking a postdoc to study the development & individual-level organization of brain circuits supporting (in)flexible behavior in psychiatric populations. 🧠 Precision functional mapping, fMRI, normative modelling Details 👉 tinyurl.com/3h8tcv2e 🗓️ Apply by Dec 10! Please RT 🙌
- Reposted by Claire O'Callaghan🔥🔥Great news!🔥🔥 The registration deadline for the Noosa Brain Workshop is extended to Nov 17. Register by this date to guarantee accomodation: monash.edu/turner-insti...
- Reposted by Claire O'CallaghanSuzanne Haber was just elected to the National Academy of Medicine! Her work on the organization of the cortex and basal ganglia has had a huge impact. Please take the opportunity to congratulate her the next time you see her. www.urmc.rochester.edu/news/story/u...
- Reposted by Claire O'CallaghanThe final paper of my PhD is now out as a preprint. This is a follow-up piece in series of two companion papers modelling awareness and suppression in a new variant of continuous flash suppression. arxiv.org/abs/2510.17154 🧵 1/3
- Reposted by Claire O'CallaghanReally interesting work by Bakhurin and colleagues challenging the reward prediction error hypothesis of dopamine: www.nature.com/articles/s41... I love this figure which both echoes and undermines the famous figure from Schultz et al. (1997).
- Reposted by Claire O'CallaghanAs I argue in #PlatypusMatters, Australia has the world's best mammals, but is sadly the worst place on Earth to be a mammal, with the planet's worst #extinction rate. The Christmas Island shrew is now the latest species to be officially declared extinct. www.theguardian.com/environment/...
- Reposted by Claire O'CallaghanAI-generated content is flooding the internet, and we're entering a new era of information overload. Watch our latest video to find out how AI slop affects the internet and why kurzgesagt videos will always remain human-made: kgs.link/AISlop
- Reposted by Claire O'CallaghanOur new paper is out in Current Opinion in Behavioral Sciences; a perspective paper on the DMN, titled "Embodying the default mode network: self-related processing from an embodied perspective" www.sciencedirect.com/science/arti...
- Reposted by Claire O'CallaghanThe current environment is making it near impossible to run clinical trials in the UK. One key issue discussed in @brain1878.bsky.social is the duplication - or worse - of regulatory oversight at NHS hospitals & universities. My views on how to change the system academic.oup.com/brain/articl...
- Reposted by Claire O'CallaghanCongrats to Charlotte Taylor and team for dissecting how astrocyte networks integrate histamine to modulate adenosine over sleep and wake in unexpected ways: dx.plos.org/10.1371/jour... @vincenttse.bsky.social @maxine.science @trishavv.bsky.social
- Reposted by Claire O'CallaghanCheck out our resource for navigating and analyzing spatial transcriptomics data in the thalamus, which we fondly call "the THALMANAC" (𝐓𝐇𝐀𝐋amus 𝐌ERFISH 𝐀𝐍alysis and 𝐀𝐂cess), now live on bioRxiv: www.biorxiv.org/content/10.1...
- Reposted by Claire O'Callaghan🚨 New paper in Nature Methods: HippoMaps: multiscale cartography of the human hippocampus Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG) Led by @jordandekraker.bsky.social docs: hippomaps.readthedocs.io paper: doi.org/10.1038/s415...
- Reposted by Claire O'CallaghanYou can sign up for the early access to the new Sea Hero Quest: seaheroquest.com
- Just discovered (a bit late I admit) this fascinating talk from @hugospiers.bsky.social Now I really want to play that SeaHeroQuest game! Hope it gets available again soon!
- Reposted by Claire O'Callaghan[This post could not be retrieved]
- Reposted by Claire O'Callaghan📢 OHBM Australia 2025 Updates! 🖼️ Poster abstract submissions open until Oct 20 👉 Submit here: ohbm-aus.github.io/posts/2025-a... 🏆 Award nominations are now open! 🎖️ Early Career Researcher Award 🌟 Emerging Leadership Award 🗓️ Due by Oct 20 👉 ohbm-aus.github.io/posts/call-f...
- Reposted by Claire O'CallaghanAt #ICON? – Join us tomorrow to hear about novel measurement & manipulation approaches for neuromodulatory systems! 🗓️Sept 19, 🕚11:45 am 🏫Room Sé #ICON2025 #CogNeuro #AcademicSky #LocusCoeruleus #neuroskyence
- Reposted by Claire O'Callaghan🔵 I'm interrupting my social media hiatus to flag this important preprint from the Bruchas lab (is he not on Bluesky!?) together with @davidweinshenker.bsky.social. Very difficult experiments to show that dopamine release from LC terminals is independent of VTA 🔥 www.biorxiv.org/content/10.1...
- Reposted by Claire O'CallaghanDon't forget! Abstracts due Sept 22 📝 Don’t miss out!
- ✨✨ We are excited to announce the OHBM Australian Chapter 2025 Annual Meeting! 🧠🇦🇺 📢 Abstract submissions & registration now OPEN (abstract submission closes September 15th at 5pm) 📍 Melbourne 🏙️☕ 📅 Wednesday, November 12, 2025 ohbm-aus.github.io/posts/2025-a... We hope to see you there! 🤩
- Reposted by Claire O'CallaghanInterested in hippocampal dynamics and their interactions with cortical rhythms? Our physically constrained model of cortico-hippocampal interactions - complete with fast geometrically informed numerical simulation (available at embedded github repo) www.biorxiv.org/content/10.1...
- Reposted by Claire O'Callaghanwww.biorxiv.org/content/10.1... Representational Geometries of Perception and Working Memory: A Pilot Study Tomoya Nakamura's first fMRI project ... in which we hereby release a preprint as a way of pre-registration 🧠📈
- Reposted by Claire O'CallaghanCome to Melbourne for the 2025 Conference of the Australasian Society for Philosophy and Psychology Check out the great keynotes - submit your abstract Come join this exciting community of researchers Nov 24-25 - Register now! #philosophy #neuroskyence #philsky sites.google.com/monash.edu/a...
- Reposted by Claire O'CallaghanOf potential interest to those keen on motor control and/or multi-task networks. Congrats to Elom and Eric. www.biorxiv.org/content/10.1...
- Reposted by Claire O'CallaghanExcited to share my latest work with @jonathanamichaels.bsky.social @diedrichsenjorn.bsky.social & @andpru.bsky.social! We asked: How does the motor cortex account for arm posture when generating movement? Paper 👉 www.biorxiv.org/content/10.1... 1/10
- Reposted by Claire O'CallaghanOnline Now: Noradrenaline drives learning across scales of time and neurobiological organisation
- Reposted by Claire O'CallaghanNew preprint! We are pleased to share our Hierarchical Bayesian framework for Interoceptive Psychophysics! Implemented in rstan, we provide a complete suite of tools spanning model comparison, parameter recovery, multifactor designs, power analysis, and more! 🎯 www.biorxiv.org/content/10.1...
- Reposted by Claire O'Callaghan🚨🚨🚨 Don't forget our annual meeting is coming up! Registration and abstract submission is open!🚨🚨🚨
- ✨✨ We are excited to announce the OHBM Australian Chapter 2025 Annual Meeting! 🧠🇦🇺 📢 Abstract submissions & registration now OPEN (abstract submission closes September 15th at 5pm) 📍 Melbourne 🏙️☕ 📅 Wednesday, November 12, 2025 ohbm-aus.github.io/posts/2025-a... We hope to see you there! 🤩
- Reposted by Claire O'Callaghandoes someone good at coding & analysis want to work remotely w/ us in the coming few months (before end of 2025), as a paid consultant? project will be on neurofeedback (fMRI, ECoG, calcium imaging). we'll work towards developing the experiments & analysis pipelines together. if so pls DM me ur CV🧠📈
- Adaptive learning is coordinated across behaviour, time and neurobiology (from synapses and dendrites, to astrocytes and the systems level). If you’ve ever wondered how noradrenaline helps shape these multiscale learning processes, you might like this: www.cell.com/trends/cogni...
- Free access link authors.elsevier.com/a/1lgsH4sIRv... #neuroskyence
- Reposted by Claire O'CallaghanThe Australasian Dark Sky Alliance have created a petition to get the Aust. Govt to create legislation that limits light pollution and preserve Australia's Dark skies. Important for human health, wildlife and #Astronomy! Australians can sign here: www.aph.gov.au/e-petitions/... 🔭☄️
- OHBM Oz rego + abstracts now open. Get amongst it!
- ✨✨ We are excited to announce the OHBM Australian Chapter 2025 Annual Meeting! 🧠🇦🇺 📢 Abstract submissions & registration now OPEN (abstract submission closes September 15th at 5pm) 📍 Melbourne 🏙️☕ 📅 Wednesday, November 12, 2025 ohbm-aus.github.io/posts/2025-a... We hope to see you there! 🤩
- Reposted by Claire O'Callaghan✨✨ We are excited to announce the OHBM Australian Chapter 2025 Annual Meeting! 🧠🇦🇺 📢 Abstract submissions & registration now OPEN (abstract submission closes September 15th at 5pm) 📍 Melbourne 🏙️☕ 📅 Wednesday, November 12, 2025 ohbm-aus.github.io/posts/2025-a... We hope to see you there! 🤩
- Reposted by Claire O'Callaghan“The moon, it turns out, is a great place for men.” Nathan Heller reflects on E. B. White’s “perfect paragraph” on the 1969 moon landing.
- Reposted by Claire O'CallaghanHere's the latest installment in my series on neuroscience and the hyperreal. I look at the potential dangers of "walled garden thinking", and why extensible modeling is important. open.substack.com/pub/yohanjoh... #neuroscience
- Reposted by Claire O'CallaghanInterested in Network hubs, cortical hierarchies, and gradients? Ever wonder where they come from? Check our latest review, where we cover different approaches to mapping hubs, models for their evolution, and mechanisms for how they develop: osf.io/preprints/os...
- Reposted by Claire O'CallaghanMy PhD student @leonielorenz.bsky.social (with Eva Geissen) has made this nice (free) online course to introduce mathematical modelling for biology: www.ebi.ac.uk/training/onl... Including both molecular and epidemiological examples