Lena Palaniyappan
Psychiatric researcher
- Reposted by Lena PalaniyappanOur most read 2025 article explores AI-generated teaching signals in psychiatry, helping clinicians sharpen clinical sense-making. Read it now ▶️ ow.ly/I57u50XWp65 👥 Lena Palaniyappan, Priyadharshini Sabesan #BestofCSP
- Reposted by Lena PalaniyappanThe Mach-Gaensslen Foundation of Canada is happy to announce the 2025 winner of the Royal-Mach-Gaensslen Prize for Mental Health Research. This year's recipient is Dr. Lena Palaniyappan with the Douglas Mental Health University Institute in Montreal. www.theroyal.ca/news/dr-lena...
- Reposted by Lena PalaniyappanKick off the new year with the Neurogenesis Speaker Series! 🎤🧠 Join Manuela Ferrari & @lenapl.bsky.social at @theneuro.bsky.social on Jan. 21, 2026, for two exciting talks on their research in mental health, followed by a meet-and-greet reception. 🧀 🫵 Register now: mcgill.ca/x/5kz @mcgill.ca
- Quantitative semiology: harnessing AI-generated teaching signals in psychiatry cdnsciencepub.com/doi/10.1139/...
- Reposted by Lena PalaniyappanNew review paper on theory of mind/mentalizing and spontaneous speech/language. Led by Chaimaa El Mouslih, and co-authored with @vegashodgins.bsky.social and @lenapl.bsky.social www.mdpi.com/2076-328X/15...
- Reposted by Lena PalaniyappanCheck out this 🆕 paper form @lenapl.bsky.social et al showing that speech spectrograms can track negative symptom severity in schizophrenia www.nature.com/articles/s44...
- Reposted by Lena Palaniyappan🚨 NEW RESEARCH! ⚕️ 🩺 🧠 Elleuch et al. explore the association of grammatical challenges in people with Schizophrenia in a systematic review and meta-analysis of 45 studies. bit.ly/4kZnq66 @lenapl.bsky.social
- One of the largest longitudinal study of computational speech and language features and psychosis from @stanglab.bsky.social Tang & colleagues! www.nature.com/articles/s44...
- Reposted by Lena Palaniyappan#ThisWeekInNPP This study identified a prefrontal-limbic structural covariance network with ⬇️ gray matter volume specific to treatment-resistant schizophrenia, linked to serotonergic, glutamatergic, histaminergic, & opioid receptor distributions 🧠 www.nature.com/articles/s41...
- www.nature.com/articles/s41... People with schizophrenia that is resistant to treatment may have specific prefrontal-limbic brain deficits linked to non-dopaminergic neurotransmitter systems—highlighting the need for therapies beyond antipsychotics. #schizophrenia #neuroscience #mentalhealth
- Reposted by Lena PalaniyappanVery, very obviously we need to emphasize science-informed preventative strategies. Public health experts – myself included – have focused on this for decades! But phrase "root causes" long ago morphed into a red flag for bunk. 🚩 news.immunologic.org/p/real-root-... @drandrealove.bsky.social👇
- Reposted by Lena PalaniyappanCongratulations to @lenapl.bsky.social, @sylvainbaillet.bsky.social and the whole team on the boost from the @wellcometrust.bsky.social for the DIALOG initiative douglas.research.mcgill.ca/news/underst...
- Reposted by Lena PalaniyappanDrs. Peter Van Dyken and Lena Palaniyappan (@lenapl.bsky.social) (@schulichmeddent.bsky.social)'s research trainee study on graph theory and U-fibre network in people with #Schizophrenia: www.psifoundation.org/funded-resea... #SchizophreniaResearch
- Excellent synergy here, looking forward to it @sylvainbaillet.bsky.social !
- Looking forward to working with @lenapl.bsky.social through this transformative grant from @wellcometrust.bsky.social, leveraging LLMs and time-resolved imaging of natural speech processes in psychotic disorders. www.neurospeed-bailletlab.org/news/dialog-... @mcgill.ca @theneuro.bsky.social
- Reposted by Lena PalaniyappanWestern University is seeking applications for Canada Excellence Research Chairs. Please reach out if you are interested in Theme 2: Neuroscience. Western has extraordinary strengths in cognitive, molecular and systems neuroscience across species (rodents, NHPs, humans) uwo.ca/research/cer...
- Reposted by Lena PalaniyappanGreening the lab: Researchers are a group that can take concrete steps to reduce the environmental footprint associated with their activities. ➡️ www.jpn.ca/lookup/doi/1...
- Reposted by Lena PalaniyappanTopiramate for treatment of behavioural disorders in Prader–Willi syndrome: Topiramate is effective in treating compulsive behaviours associated with PWS, but requires monitoring. ➡️ www.jpn.ca/lookup/doi/1...
- Reposted by Lena Palaniyappan📣 We are proud to announce that the Wellcome Trust has awarded Dr. Palaniyappan! 📣 Nous sommes fiers d’annoncer l'obtention d'une subvention de la Fondation Wellcome Trust à Dr Palaniyappan pour soutenir le projet DIALOG! More infos / plus d'infos : douglas.research.mcgill.ca/news/underst...
- We show cannabis use disorder is associated with higher midbrain neuromelanin, where such an increase is associated with #psychosis severity. The higher the use, the greater the putative dopamine turnover. Led by Jessica Ahrens @healthsciences.mcgill.ca IPN jamanetwork.com/journals/jam...
- When we are depressed, we not only have negative thoughts but also experience a muddled, disorganized thinking process. We propose some steps to make progress in understanding and reducing the burden of disorganization in #Depression link.springer.com/article/10.1...
- www.sciencedirect.com/science/arti... We see a prominent excess of first-person pronouns in #schizophrenia, with no excessive inter-individual variability. While not a direct comparison, this effect (d=0.89) is >> than striatal dopamine excess or prefrontal glutamate reduction reported to date.
- Dog person open.substack.com/pub/lenapl/p... #poetry
- Transcriptional substrates of cortical thickness alterations in anhedonia of #depression ... www.sciencedirect.com/science/arti...
- www.sciencedirect.com/science/arti... Are hallucinations a result of pathological geenration of words? An experiential account argues so. A commentary with @olidn.bsky.social
- Reposted by Lena PalaniyappanOur Ready to Connect (eigsti.psy.uconn.edu/home-2/ready...) project is hiring a postdoc (at UConn): eigsti.psy.uconn.edu/open-postdoc... We investigate conversational success in autistic and non-autistic teenagers during realistic social interactions. Ideal start date: May 15, 2025
- www.sciencedirect.com/science/arti... Impoverished articulation of perceptual processes in #schizophrenia is linked to the structure of #cerebellum For a special issue in Neuropsychologia edited by @valentinabambini.bsky.social & team!
- www.bpsgos.org/article/S266... White matter does not seem to deteriorate in the first few years of #psychosis in patients receiving treatment.But negative symptoms consistently track white matter integrity.
- How do stimulants, MDMA, #cannabis, #ketamine and #psychedelics affect speech & language? Can we use these behavioral effects to test for intoxication? Our new pre-registered systematic review journals.sagepub.com/doi/10.1177/...
- If you are in Montreal, apply!
- #psychiatry #computational #LLMs jpn.ca/content/50/1... Is pragmatism antithetical to computational psychiatry?
- Reposted by Lena PalaniyappanWell just received this email regarding a paper under review:
- How long before we lose #pubmed ? I see a weird 'high traffic' notice on the site!
- Reposted by Lena PalaniyappanToday is Retraction Day, when we observe the anniversary of the retraction (Feb. 2, 2010) of the fraudulent paper that purported to show a link between vaccines and autism. 🧪#medsky
- Congrats all! A proud moment for ceymh-cesmj.ca/youth-family... who shaped 2 of the 4 funded grants this time!
- - Fall 2024 CIHR Project Grant Results - 📣 Congratulations to our CIHR Project Grant Recipients!! *** - Résultats des demandes de Subvention Projet des IRSC Automne 2024 - 📣Félicitations à tous les lauréats! More info / Plus d'infos : buff.ly/42yZpw2
- Well done, Tiana! douglas.research.mcgill.ca/news/hsi-wei.... Thanks to @sylvainbaillet.bsky.social & @magnetokrishio.bsky.social 's awesome groups - we are getting full-time into the oscillatory dynamics of psychosis.
- Reposted by Lena PalaniyappanI've been working with the Wilson-Cowan neural mass model for a while now and, over time, I've accumulated a bunch of tools to explore/visualize it. I recently decided to collect it all into a github repository available here if anyone is interested: github.com/NeuroLife77/...
- Reposted by Lena PalaniyappanHappy 30th birthday year to SPM!! 🎈🍰 To get the party started, we are delighted to announce SPM 25.01, a major new version of the open-source neuroimaging software. Read the preprint to discover what's new arxiv.org/pdf/2501.12081 and download SPM for free from Github github.com/spm/spm/rele...
- Reposted by Lena PalaniyappanReminder! Submit your abstracts for poster and oral presentations for our DISCOURSE Satellite Meeting by 2/14/25! forms.gle/nW5K9MGtBkqQ...
- douglas.research.mcgill.ca/offres_d_emp... With ~C$9.5M+ investment from @wellcometrust.bsky.social, we are setting out to study why disorganized speech/behaviour occur in #psychosis #bipolar & how to reverse it. Join us for this 7-country study with MEG+PET+MRI & communication remediation.
- Reposted by Lena Palaniyappan
- www.nature.com/articles/s41.... Both childhood and adult trauma converge on caudate volume. Oxidative stress and glutamate transmission may have an influence on this convergence. With Qiang Luo & team at Fudan.
- Reposted by Lena PalaniyappanGreat paper on the challenges of precision psychiatry, in particular modelling/predictions re complex causal/risk factors www.cambridge.org/core/journal...
- Reposted by Lena PalaniyappanNew 📃by #WIN members @andpru.bsky.social, Dr. Stefan Everling, Dr. Wataru Inoue, Dr. Julio Martinez-Trujillo, and colleagues - Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties... pubmed.ncbi.nlm.nih.gov/39772396/
- Reposted by Lena PalaniyappanPresent your great work at #CPConf25 and join us in Tübingen - poster abstract submission now open!
- Poster submissions for the Computational Psychiatry Conference 2025 in Tübingen are now open. Deadline is 7th February. Symposium submissions are open until 15th January. www.cpconf.org. Please RB.
- "Consider the practical effects of the objects of your conception. Then, your conception of those effects is the whole of your conception of the object" - CS Peirce
- Reposted by Lena Palaniyappan📣Join us on January 14, 2025 for our next Experiential Science Talk with Mykaell Blais #CEYMH - 📣 Rejoignez-nous le 14 janv. 2025 pour le prochain séminaire sur la science expérientielle avec Mykaell Blais #CESMJ buff.ly/3W5IHjN
- www.cambridge.org/core/journal... Brain state transitions and working memory in schizophrenia + indirect relationships with insulin signalling
- Reposted by Lena PalaniyappanYesterday, we lost William Labov, a foundational figure in sociolinguistics. In his Abralin Talk, Labov reflected on a lifetime of scholarship that has mentored generations and advanced the pursuit of social equity through linguistics.
- Reposted by Lena PalaniyappanA lovely obituary for Bill Labov in the Inquirer.
- “Are we what we do with time, or are we what time does with us?” - Mahmoud Darwish
- Reposted by Lena Palaniyappan[This post could not be retrieved]
- Reposted by Lena Palaniyappan💥 Some POST DOC JOB news 👀... I'm very happy to say that @melgaby.bsky.social, @mattnour.bsky.social, @mariaeckstein.bsky.social and I have been awarded funding from @wellcometrust.bsky.social to look at how planning 📝and mental models of the world 🌍 are affected by psychosis...
- Reposted by Lena Palaniyappan#WIN member Dr. Julio Martinez-Trujillo reappointed as Provincial Endowed Academic Chair in Autism. www.schulich.uwo.ca/about/news/2...
- Reposted by Lena PalaniyappanGABA, Glutamate dynamics and BOLD observed during cognitive processing in psychosis patients with hallucinatory traits biorxiv.org/content/10.1101/202…
- Reposted by Lena PalaniyappanDear academics We could dramatically reduce our administrative workload if we all just agreed not to ask for reference letters until we made our list of finalists. This is massive collective action problem has already been solved by… *checks notes* …every other industry on earth.
- With deadlines to chase all around the year, we sometimes don't see how much a small team of individuals that gather around an idea end up accomplishing in one year! 2024 has been a great year that taught us a lot of new things. Looking forward to 2025!
- Reposted by Lena PalaniyappanNew open access paper on #bilingualism, #multilingualism, #psychosis, and #schizophrenia, led by Vegas Hodgins. www.cambridge.org/core/journal...
- Reposted by Lena PalaniyappanHello bsky. Good to be here. I'm hiring! Can't think of a better inaugural post than to share details of new 2-year research fellow post we're advertising for an outstanding epidemiogist to join my team to work on improving population mental health. tinyurl.com/28mlykr9 #CausalSky #EpiSky
- Reposted by Lena PalaniyappanMetastability demystified — the foundational past, the pragmatic present and the promising future Dynamic systems theory review paper with Fran Hancock, Fernando Rosas & friends rdcu.be/d3bh9
