Quentin Huys
Professor of Computational Psychiatry @UCL. www.acplab.org. CI of RELMED study relmed.bsky.social / relmed.ac.uk.
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- The really exciting moments. Many congratulations Dr Chen! @jiazchen.bsky.social
- Postdoctoral research position in #ComputationalPsychiatry and #EEG as part of relmed.ac.uk trial testing reinforcement learning as biomarker for antidepressant treatment response. www.ucl.ac.uk/work-at-ucl/... @uclbrainscience.bsky.social @mikebrowning.bsky.social @relmed.bsky.social
- Reposted by Quentin Huys📣🔥Thrilled to announce that 2026 Computational Psychiatry Conference will take place in New Haven, CT, btw July 14-16 - www.cpconf.org @robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop More info to come soon!
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- New #neurojob #psychiatryjob #jobalert. www.northlondonmentalhealth.nhs.uk/current-vaca.... Focus is on clinical trials for mood disorders, with close links to @uclpsychiatry.bsky.social @uclqsion.bsky.social and @mpc-comppsych.bsky.social
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- New #job alert! Clinical research fellow / postdoc in #computationalpsychiatry at the @mpc-comppsych.bsky.social / @uclqsion.bsky.social and UCL psychiatry. We will aim to understand the computations engaged by serotonin in the treatment of depression. Please re-sky. www.ucl.ac.uk/work-at-ucl/...
- Proud husband! Ivana Gavric's new single is out m.youtube.com/watch?v=OegD...
- Reposted by Quentin Huys🧠 We're hiring a computational postdoc! 3+ years with me & @mitulamehta.bsky.social on @wellcometrust.bsky.social funded social cognition/paranoia research at the IoPPN. Lead & develop computational work, collaborate with experimentalists on psychosis/THC data. DM for details! lnkd.in/eCMy9Jf5
- The brain's priors have been found! They were hiding everywhere: www.nature.com/articles/s41.... So if this is true for "simple" decisions, it should also be true for more complex ones, like, say, emotions, right?
- Reposted by Quentin Huys🧵 New paper! We studied depression symptoms and goal-directed decisions under uncertainty @shiyiliang.bsky.social, with @evanrussek.bsky.social & @robbrutledge.bsky.social Surprisingly, we found that apathy–anhedonia was linked to enhanced goal-directed behavior. www.biorxiv.org/content/10.1...
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- Reposted by Quentin Huys📢 We are hiring! 📢 For our @wellcometrust.bsky.social grant on information gathering biases in #OCD and #Schizophrenia, we are looking for a Postdoc in Computational Modelling, supervised by Peter Dayan and myself. Interested? See all the details in the job advert here: devcompsy.org/wp-content/u...
- Another exciting new job opening at @uclpals.bsky.social with Niko Steinbeis and Essi Viding - www.ucl.ac.uk/work-at-ucl/... #neurojob #computationalpsychiatry
- Still open!
- New position alert! This is an exciting position for a Specialty Doctor to take a leading role in developing the North London Mood Disorders Research Clinic in a national network of Mental Health Mission research clinics apps.trac.jobs/job-advert/7.... @noclor.bsky.social @uclpsychiatry.bsky.social
- Reposted by Quentin Huys🚨 We’re hiring: Associate Professor/Professor of Cognitive Neuroscience 🧠 Lead pioneering imaging-informed cognitive neuroscience research 🌍 Open to international applicants | Visa sponsorship available 📍 Permanent, full-time, on-site 🔗 Apply now: www.ucl.ac.uk/work-at-ucl/...
- New position alert! This is an exciting position for a Specialty Doctor to take a leading role in developing the North London Mood Disorders Research Clinic in a national network of Mental Health Mission research clinics apps.trac.jobs/job-advert/7.... @noclor.bsky.social @uclpsychiatry.bsky.social
- New position alert! This is an exciting position for a Specialty Doctor to take a leading role in developing the North London Mood Disorders Research Clinic in a national network of Mental Health Mission research clinics apps.trac.jobs/job-advert/7.... @noclor.bsky.social @uclpsychiatry.bsky.social
- Reposted by Quentin HuysI still get chills Meet Mike *30+ years severe depression *first hospitalized @ 13y *20 meds *3 rounds of ECT *2 near-fatal suicide attempts Mike felt joy for the first time in decades after we turned on his new brain pacemaker or PACE see videos, read paper, follow thread doi.org/10.31234/osf...
- Associate Professor/Professor of Cognitive Neuroscience job opening in our own @imagingneuroucl.bsky.social department. Details here: www.ucl.ac.uk/work-at-ucl/...
- Here we go. #cpconf2025 is over. Thank you all for a superb conference and in particular @tobiasuhauser.bsky.social and Susan Fischer!
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- The bar is high!
- #CPConf2025 is exploring multidimensional reward functions #RufusTempleOrchestra
- @roelandheerema.bsky.social at #cpconf2025 talking about a new task linking specific emotional appraisals to computational states.
- Jiazhou Chen at #cpconf2025 on generalisation of MEG signatures of emotional states.
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- Can we quantify mental states using LLMs? What are the limits? When does it and when does it not work and why? Jakub Onysk talking #cpconf2025
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- V important meta-analysis doi.org/10.1001/jama...: Discontinuation symptoms 1 week post stopping antidepressants was below the threshold for clinically significant discontinuation syndrome. Later worse mood is likely depression relapse @jfhayes.bsky.social @sameerjauhar.bsky.social.
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- Deadline today - looking forward to the applications!
- @yanivabir.bsky.social and Zeguo Qiu are presenting exciting new behav & eeg battery of reinforcement learning tasks developed to see if different rl processes are selectively engaged by DA and 5HT. #BAP2025 @bapsych.bsky.social
- "substantially" is notable given this is in people with treatment-resistant depression, i.e. when there is a depression that has not responded to at least two other antidepressants.
- Our new study published in TheLancetPsych! We found that pramipexole augmentation substantially reduced depressive symptoms in patients with treatment-resistant depression over 48 weeks of treatment. This is an important advance in how we treat depression! 1/6 www.thelancet.com/journals/lan...
- @mikebrowning.bsky.social's paper on pramipexole in treatment-resistant depression is now out - very encouraging results authors.elsevier.com/sd/article/S....
- Reposted by Quentin HuysEarly registration is OPEN for the next #BrainConference! 🧠 🇬🇷 For the first time ever, the Brain Conference is heading to Fodele Beach in Crete, Greece, and you’re invited! 🌟 Register by 10 July 2025 👉 loom.ly/ei_yabg @lundbeckfonden.bsky.social @brainprize.org
- Thank you @santhouse.bsky.social for this exploration of the blurry line between healthy and ill, of how cultural norms affect our views of who is ill. It highlights challenges when we get this wrong - like raising awareness without having sufficient answers. A very curageous and necessary book!
- Looking forward to reading @santhouse.bsky.social's new book! What indeed is health and what is normal?
- Delighted to announce this position www.northlondonmentalhealth.nhs.uk/current-vaca.... It's part of the Mental Health Mission Mood Disorders Research Clinic Network, aiming to support clinical trials in mood disorders in the UK. Should be very interesting! oxfordhealthbrc.nihr.ac.uk/mhm/mood-dis...
- Super to see this out! Pavlovian biases have shown predictive power a surprising range of settings, e.g. long-term course of alcohol use. Here, we find that Pavlovian biases are engaged by therapy; and that this engagement medicates outcomes in NHS setting. Congratulations @liobanause.bsky.social!
- Huge thanks to everyone that made this project possible: Daisy Crawley, Lana Tymchyk, Anna Hall, Jakub Onysk, Tore Erdmann, Elliot Wimmer @elliottwimmer.bsky.social, Isabel Berwian, Agnes Norbury @agnesnorbury.bsky.social and Quentin Huys @docqhuys.bsky.social!
- Reposted by Quentin HuysNEW DEADLINE: Friday 20th June 🚨 MEG‑UKI 2025 lands in London (16–18 July)! A 3-day deep dive into the brain—naturalistic neuroscience, OP-MEG, cutting-edge methods, and real-world impact. Keynotes by Dominik Bach & Jamie Ward. Art, abstracts, and more! Register here: meguk.ac.uk/registration/
- This was hard work, but ultimately there is support in the literature that engagement of different RL processes by serotonergic and dopaminergic/noradrenergic pharmacological interventions may be a promising route to follow. The @relmed.bsky.social study will do just that.
- 🚨 New paper out in JAMAPsych: 🦣 project led by the brilliant @anahitm.bsky.social & @docqhuys.bsky.social ’ group. Our meta-analysis found that #dopamine & #serotonin have distinct effects on reinforcement learning. A step toward biomarker guided treatment? jamanetwork.com/journals/jam...
- Same for peer review methinks - let's not throw the baby out with the bathwater. www.science.org/content/arti...
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- RELMED.ac.uk is now open to recruitment. This @wellcometrust.bsky.social-funded study wellcome.org/research-fun... will ask whether reinforcement learning tasks are differentially sensitive to dopaminergic and serotonergic antidepressants.
- All the hard work was done by @yanivabir.bsky.social @hylu.bsky.social @muzhiw.bsky.social Elizabeth Zeguo Qiu, Michaela Poppe, @nikkisingh.bsky.social, Raziya Zharmakhan @qdercon.bsky.social @tsedlinska.bsky.social and too many outstanding collaborators to list!
- Thank you @clairelavalley.bsky.social and @rssmith.bsky.social. Striking to see aversive pruning altered in people with methamphetamine use, particularly given the results in depression (dx.doi.org/10.1017/S003...).
- Huge congrats to @clairelavalley.bsky.social on this new paper. www.nature.com/articles/s41.... Results show that methamphetamine users show a specific deficit in model-based planning, in which they fail to simulate plans with large short-term losses (elevated aversive pruning). Brief thread below!
- Looking forward to giving a pintofscience.co.uk talk on the mathematics of healthy emotions next week Tuesday evening pintofscience.co.uk/event/from-e....
- New John Slate chair in psychiatry at Exeter: jobs.exeter.ac.uk/hrpr_webrecr...
- Christian Volkmann and Subat Abulikemu's new analysis examining the relationship between depression and discontinuation symptoms after antidepressant discontinuation dx.doi.org/10.1007/s004... with excellent thread here: x.com/CVolkmannMD/.... Short summary: the details do matter.
- Reposted by Quentin Huys📢 We have an opportunity for students to join our PhD programme in Theoretical Neuroscience and Machine Learning this September. Application deadline is 27 May 2025. Information & how to apply: www.ucl.ac.uk/gatsby/study-and-work/gatsby-unit-phd-programme
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- Final chance!!!
- Late Abstract Submissions Now Open – Limited Space Available! We are now accepting late abstract submissions for the 2025 Computational Psychiatry Conference in Tübingen! cmt3.research.microsoft.com/CPConf2025/S... (1/3) #CPConf2025
- Congratulations @toshi-frkw.bsky.social, this is a real tour de force! Maybe, finally, dodo the bird can get some rest. Differential treatment effects for different outcomes, including also interesting insights into different psychotherapy control conditions.
- Published today in Nature Medicine. In one of the world’s largest RCTs of its kind (n=3,936), a smartphone app teaching 5 key cognitive-behavioral therapy skills improved subthreshold depression—and the effects lasted 6 months. www.nature.com/articles/s41...
- Looking forward to reading @santhouse.bsky.social's new book! What indeed is health and what is normal?
- Congratulations Jenny!
- Fully funded MSc in clinical research delivery: oxfordhealthbrc.nihr.ac.uk/fully-funded...
- Congratulations on a great piece of work!
