Jess Kelley
Postdoc with Dominika Gruszka at the University of Oxford. Previously DPhil student in the Klose lab. Interested in the molecular mechanisms of chromatin-based processes. She/her
- Reposted by Jess KelleyCome to hear Alan's great new story on SET1/MLL proteins and transcription next Wednesday. @fnucleosome.bsky.social
- 🥁 #FragileNucleosome is back on Jan 28! We are very excited to host @au-ho-yu.bsky.social and @gcloner.bsky.social as our first speakers of 2026! 📋Please don't forget to register for our 2026 seminar series: us06web.zoom.us/webinar/regi...
- Reposted by Jess KelleyUnbelievably, #DuvetKnowItsChristmas generates such good will on social media that over the years we've raised somewhere approaching a quarter of a million quid for homeless charities. If you can spare a bob or two, sling some to Centrepoint, and here's the link: www.gofundme.com/f/duvet-know...
- This year I'm hosting Christmas in my 1-bed flat. My brother has inherited last year's airbed setup and I've upgraded to an actual bed! Just a (freezing) 10-minute cycle down the road to my friend's house to get to it... I get to hang out with Imogen though so I'm still happy #DuvetKnowItsChristmas
- I finally get to join an honoured festive tradition in #DuvetKnowItsChristmas Parents are stopping over in my 1-bed flat before we go join the family gathering in the morning. They get my bed, I get the airbed on my own living room floor. Also featuring camping chair to supplement my 2-seat sofa
- Shout-out to @fairbanc.bsky.social for letting me sleep in her house and hang out with her cat
- Reposted by Jess KelleyExcited to share our new preprint from the Klose lab, where we investigate how SET1/MLL complexes shape H3K4me3 and regulate transcription in mouse ES cells. www.biorxiv.org/content/10.6...
- Reposted by Jess KelleyVery proud to have our latest work now online in @natsmb.nature.com. A wonderful team effort across the centromere community, across @jansenlab.bsky.social @naltemose.bsky.social @dfachinetti.bsky.social and Giunta labs. Happy reading! 1/4 www.nature.com/articles/s41...
- Reposted by Jess KelleyThis October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 20/31 Prompt RIVALS Pdb: 8V27 & 8G6S Two rival histone modifications on a nucleosome. Ubiquitination of H2BK120 activates genes while H2AK119 represses them. Next: BLAST Suggestions?
- Reposted by Jess KelleyTime to talk about one of my favourite Oxford buildings, 26-27-28 Cornmarket!! Popularly known as The Old Pret
- If you're looking for Oxford local news that actually reports local news, the Oxford Clarion is worth a follow and subscribe!
- Oxfordshire’s weekly news update with all the stories we’ve broken this week: ✅ 10,000-home new town in North Oxfordshire ✅ Why Oxford–Milton Keynes trains haven’t started ✅ The new café run by monks ❌ Cotswold celebrities and Emma Watson Read it online or by email: oxfordclarion.uk/clarion-week...
- Reposted by Jess KelleyWho can work in science, EVERYONE #pride
- Reposted by Jess KelleyEPIGENETIC HULK READY TO SMASH AGAIN! GET IN LOSERS!
- Reposted by Jess Kelley🔬 New from the Farnung Lab: We established a fully in vitro reconstituted chromatin replication system and report the first cryo-EM snapshots of the human replisome engaging nucleosomes. Brilliant work by @felixsteinruecke.bsky.social with support from @jonmarkert.bsky.social! tinyurl.com/replisome
- Reposted by Jess KelleyRNA xkcd.com/3056
- Reposted by Jess KelleyResearch @oxfordbiochemistry.bsky.social @ox.ac.uk supported by the Wellcome Trust (UK) and NIH (USA) reveals essential new player in the process of deciding whether genes should be made or not. Great work @jesskelley.bsky.social @robklose.bsky.social @edimitrova.bsky.social 👏 bit.ly/202502-klose
- Reposted by Jess Kelley@bencarty.bsky.social and the team did a fantastic job in a wonderful collaboration with @naltemose.bsky.social as well as Dani Fachinetti and Simona Giunta’s teams to help define the molecular basis for maintaining centromeric chromatin size and position. www.biorxiv.org/content/10.1...
- Reposted by Jess KelleyI love scientists
- Reposted by Jess KelleyDo you know a UK-based wheelchair user who works in a lab and would be willing to user-test our prototype of what is believed to be the first-ever lab coat adapted for wheelchair users? Please share far & wide! Interest form: forms.office.com/e/66FhcQjqRT More info: www.ucl.ac.uk/ucl-east/new...
- Reposted by Jess KelleySo I'll be back around then. We'll be trying to raise a bit of money for Centrepoint, bearing in mind that there are a bunch of people who have nowhere to go this evening. gofund.me/637d21d0 ENDS FOR NOW 🎄🛏️
- I finally get to join an honoured festive tradition in #DuvetKnowItsChristmas Parents are stopping over in my 1-bed flat before we go join the family gathering in the morning. They get my bed, I get the airbed on my own living room floor. Also featuring camping chair to supplement my 2-seat sofa
- Reposted by Jess KelleyGoogling Stuff: Then v Now.
- Reposted by Jess KelleyWe have had multiple discussions about why people have not previously observed the very dramatic reduction in transcription upon PNUTS depletion. So I looked at our own TT-seq data and analysed it without including the spike-in. The numbers speak for themselves! Spike-in calibration is important!
- Reposted by Jess KelleyJoin Oxford Biological Physics! #KavliOxford is inviting applications for Fellows to establish independent research groups in this dynamic, interdisciplinary field. Apply now: kavli.web.ox.ac.uk/article/2025...
- Reposted by Jess KelleyTurns out that, for me, news sites are a great way to become usefully informed about what's happening in the world, and Twitter is a great way to get uselessly stressed about it.
- Nice thread collating all these exciting new reviews! My 'to read' list has definitely just got even longer...
- As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School 🧪🧵 1/ www.sciencedirect.com/science/arti...
- Reposted by Jess KelleyOn the reading list
A special JMB issue on Transcription elongation and termination with really great reviews including @triggerloop.bsky.social @voslab.org @lucas.farnunglab.com www.sciencedirect.com/science/arti...
- Reposted by Jess KelleyThis paper is genuinely amazing! Not only is the science very cool, it is also a masterclass in scientific writing, as are most @robklose.bsky.social lab papers!
- Very excited that our paper describing a critical role for the PNUTS-PP1 phosphatase complex in transcription pause release is up online! This was a massive team effort with @edimitrova.bsky.social and the rest of the @robklose.bsky.social lab www.cell.com/molecular-ce... A short thread: (1/8)
- Repost for the morning crowd! ICYMI, our new paper on PNUTS-PP1 in transcription pause release is out now:
- Very excited that our paper describing a critical role for the PNUTS-PP1 phosphatase complex in transcription pause release is up online! This was a massive team effort with @edimitrova.bsky.social and the rest of the @robklose.bsky.social lab www.cell.com/molecular-ce... A short thread: (1/8)
- Reposted by Jess KelleyGo team PNUTS! @jesskelley.bsky.social @aleksszczurek.bsky.social @neilblackledge.bsky.social @robklose.bsky.social and Maciek!
