Wouter De Coster
Dad. Scientist at VIB. Bioinformatics postdoc. Sequencing technologies enthusiastic. Geneticist. He/him.
- I am fetching reads from cram files in Rust, using rust-htslib and a rayon thread pool. It surprises me that memory use is flat up to 5 threads, but then takes off linearly. Does anyone have a clue what is going on? @robp.bsky.social @johanneskoester.bsky.social Code: github.com/wdecoster/in...
- Reposted by Wouter De CosterWhether it's Donald Trump getting half a billion dollars from United Arab Emirates or Joe Biden getting free ice cream from a shop in Delaware, influence peddling has been a problem for both men.
- We are excited to have @minomatt.bsky.social as a keynote speaker at the Flanders Nanopore Day, alongside a wide range of @nanoporetech.com topics, spanning from microbes to plants to humans. All information - including free registration and free PromethION sequencing - at nanoporeflanders.be
- Reposted by Wouter De CosterYesterday it was cows using tools, today its penguins using satellite imagery.
- Reposted by Wouter De Coster
- Reposted by Wouter De CosterOh wow: Cryo-EM structure of #TAF15 filaments from postmortem #FTLD brains by the group of Ben Ryskeldi-Falcon at the @mrclmb.bsky.social. What an amazing tour-de-force!! 🤯 www.biorxiv.org/content/10.6...
- Join us at the Flanders Nanopore Day conference on April 17th in Antwerp, organized together with @nanoporetech.com! Details are available at nanoporeflanders.be, including registration (free), abstract submission, and project prizes with free PromethION sequencing for two selected projects.
- Reposted by Wouter De Coster#Iran is in the middle of #REVOLUTION. This isn't about inflation. It's about 47 years of oppression. Listen to the chants: "death to the dictator," calls for regime change, and demands for the Shah's return. Be the voice of the Iranian people. #DigitalBlackoutIran
- Reposted by Wouter De CosterWhat genetic change to Indian wheat led to superior baking in a tandoor? A naan sense mutation
- Reposted by Wouter De CosterNicolás Maduro Charged With Felony Oil Possession
- Reposted by Wouter De Coster„Never forget: whenever Elon Musk walks up to a podium to bullshit you about colonizing Mars or whatever, he is walking on the bodies of dead children. He yanked their food and medicine away while telling lies and cracking stupid jokes.“ @dereklowe.bsky.social as usual not pulling any punches
- Reposted by Wouter De Costerand the winner of the "2025 best thing on Internet" has just arrived neal.fun/size-of-life/ @carlbergstrom.com
- Reposted by Wouter De CosterAI ran our office vending machine for several weeks. It lost hundreds of dollars, gave away a PlayStation, bought a live fish—and taught us a lot about AI agents, writes Joanna Stern.
- Reposted by Wouter De CosterHIRING ALERT!!! 💥 We are looking for an enthusiastic postdoctoral researcher to uncover Alzheimer's disease mechanisms using state-of-the-art technologies! 🧠🧬 jobs.vib.be/j/128109/pos...
- Reposted by Wouter De CosterWe are thrilled to announce the first official release (v0.1.8) of #𝗯𝗲𝗱𝗱𝗲𝗿, the successor to one of our flagship tool, #𝗯𝗲𝗱𝘁𝗼𝗼𝗹𝘀! Based on ideas we conceived of long ago (!), this was achieved thanks to the dedication of Brent Pedersen. 1/n
- Does someone know if there public @nanoporetech.com or @pacbio.bsky.social genome sequencing data from individuals with pathogenic repeat expansions?
- Reposted by Wouter De CosterAs new human assemblies become available on beta.ensembl.org - which human reference genome will you choose? This article explores the question with insights from Ensembl’s own Fergal Martin - www.nature.com/articles/s41... #HumanGenomics #Pangenomes #ReferenceGenomes
- Reposted by Wouter De CosterDid not expect to see disk space become an issue but after a disk clean up and restart I ended up with 243 and 244 gbp for these two @nanoporetech.com flowcells 🎉🚀🧬 💚🟩💚🟩💚🟩
- Reposted by Wouter De CosterI am looking to get my hands on some #Illumina 5-base methylation data - does anyone have a bam file that I could use for some testing? Please RT for reach!
- My current favorite strategy for using LLMs to code (specifically, GitHub Copilot agent mode) is to write a paragraph or more of instructions, and finish with "Do not start writing any code yet. First, tell me all the questions you still have about this plan".
- It will generate some questions about the implementation, which it would usually try to solve on its own (get creative), and you want to avoid that. I answer the questions, and off it goes, crafting exactly what I had in mind.
- Reposted by Wouter De CosterWhy yes Windows, I did want to save this email attachment in C:\Users\pbayer\AppData\Local\Microsoft\Olk\Attachments\ooa-6b0f86af-a548-4060-9a83-7d943fcaa440\157ef8591494ef374d2433d75c318962f8bc4054af4a1be24c8e02b89b6d5ec9 that's just a logical place for it
- Reposted by Wouter De Coster(forgetting the word for antibiotics) do i need cancel culture
- Reposted by Wouter De CosterDr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.
- We are hiring a postdoctoral researcher to identify genes involved in frontotemporal dementia using short- and long-read sequencing data. More information is available at jobs.vib.be/j/124543/pos....
- Reposted by Wouter De CosterNEWS! Nation capable of spotting spurious link between paracetamol and autism still baffled by obvious link between guns and mass shootings
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minimap2.com is potentially a phishing site. Please don't use anything from that website. github.com/lh3/minimap2... - Reposted by Wouter De CosterHeads up: ignore samtools dot org, similarly minimap2 dot com and likely others. It's owned by a known phishing site and while the binaries they offer look valid currently (but note they may be serving us different binaries to others), that could change. Ie: it's not us (Samtools team)! Be warned
- Reposted by Wouter De CosterThis is awesome. @ellecordova.bsky.social
- Which tool should I use nowadays to identify pathogens in long-read DNA sequencing from human brain samples?
- Reposted by Wouter De CosterOk this is mad "...an ant that lays individuals from two distinct species. In this life cycle, females must clone males of another species because they require their sperm to produce the worker caste" www.nature.com/articles/s41...
- Reposted by Wouter De CosterFacts
- Reposted by Wouter De CosterFor @nanoporetech.com geeks I’ve just been pointed at this very helpful site - nanoporetech.github.io/ont-output-s... - I hadn't seen this before and it's very useful!
- Could you send me a Zoom link? Is Teams okay? The new coke vs. pepsi question.
- Reposted by Wouter De CosterCoukd It Have BEEN Found With Short Reads? 🧬🖥️ omicsomics.blogspot.com/2025/06/coul...
- Reposted by Wouter De CosterIf you want to check if a human gene has copy-number changes or lands in a complex region, try pangene.bioinweb.org. Recently updated with more and better assemblies.
- Reposted by Wouter De CosterThis would be a great time for everyone to be cool when reviewing manuscripts and *not* request $25,000 worth of new experiments that don’t substantially advance or validate the study...
- Reposted by Wouter De Coster🚨 Training Alert: Dive into long-read single-cell RNAseq with #scywalker 🗓️ June 5, 2025 📍 Ghent – VIB/UGent FSVM II 🎟️ Registration deadline is Monday May 26th: training.vib.be/all-trainings/scywa…
- Reposted by Wouter De CosterOur spotlight winner, Ruben Cools, presented his full talk exploring how they are bridging genotype and phenotype through long Oxford Nanopore read, single-molecule multiomics. #NanoporeConf
- If only I could use such an incredibly wide screen to browse long reads on IGV #nanoporeconf
- Reposted by Wouter De Coster[This post could not be retrieved]
- Reposted by Wouter De Coster✨ We’re off for three days of next-generation sequencing at #RNGS25 in Antwerp! Experts from academia and industry will showcase innovations transforming healthcare, agriculture, and more. 🎤 Kicking off: Rosa Rademakers on GOLGA8A repeat expansion & its link to FTD. Stay tuned! 🔬 #Genomics
- Reposted by Wouter De CosterAbout fifty years ago, NASA strapped a message in a bottle to a rocket and flung it into the deep dark It wasn’t supposed to go this far, but it did. Long past its mission, it’s still out there so far away now that a simple hello takes a day to reach it, and another day to hear if it says hello back
- Reposted by Wouter De CosterLast 2 days left to register for #RNGS2025. ⏱️So, don't miss out and register! Catch Simon Koplev's talk on the use of long reads for rare disease research. 📅19-21 March 2025 📍Antwerp, Belgium vibbio.tech/4htR01q #NGS #genomics #sequencing #omics
- Reposted by Wouter De Coster🚨The final deadline to register for #RNGS25 is this Wednesday, March 5th!🚨 Make sure to register - You don’t want to miss Prof. Bernard Thienpont (@bernthie.bsky.social)'s fascinating talk on improving patient care by using cell-free DNA methylome analysis.🧬 www.vibconferences.be/events/revol...
- How many times per day can one check the manuscript status page before it becomes excessive? Asking for a friend.
- Reposted by Wouter De CosterEvery scientist, long before they were a scientist, was a little kid who stood in front of a fish tank or stared up at the stars or turned over a rock to look at the bugs underneath and said “wow”. On the best days, working in science still feels like that.
- Reposted by Wouter De Coster📢 Our lab is looking for a bioinformatics postdoc. We have lots of exciting projects to work on, including single cell (epi-)genomics, microglia xenotransplantations and nanopore long reads splicing analysis. Look out for the official advert next week and get in touch in the meantime 🧬🧠
