Frederic Schaper
Instructor in Neurology, MD PhD | Neuroscientist at @braincircuits.bsky.social at Brigham and Women’s Hospital of MGB, Harvard Medical School | I’m Interested in neuromodulation, brain networks, and epilepsy
- Reposted by Frederic SchaperHonored to moderate a panel on noninvasive mapping of human brain circuits at MGB Neuroscience Day. Great insights from @anastasiayendiki.bsky.social @mghmartinos.bsky.social, @fredschaper.bsky.social @braincircuits.bsky.social, Alex Golby and Pravan Nanda @mgbneurosurgres.bsky.social.
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- Reposted by Frederic SchaperMassive, Herculanean work by @laurenahart.bsky.social and Garance Meyer to compile and integrate findings from DBS for epilepsy (20 targets!) including meta-analytical evidence for optimal stimulation sites for the two main targets (ANT & CM). Preprint out now 👇👇
- 🧠 ⚡️ Preprint alert ⚡️ 🧠 I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why. Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes www.researchgate.net/publication/...
- Reposted by Frederic Schaper🧠 ⚡️ Preprint alert ⚡️ 🧠 I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why. Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes www.researchgate.net/publication/...
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- Reposted by Frederic SchaperHow does early life adversity impact white matter brain connections and subsequent cognitive abilities? Adversity was associated with lower white matter integrity and later difficulty with arithmetic & receptive language yet interpersonal resilience was protective. www.pnas.org/doi/epub/10....
- Reposted by Frederic SchaperWas fun to do a podcast about our recent paper on creativity and brain disease with Dr Norman Swan @abcnewsbot.bsky.social @braincircuits.bsky.social @foxmdphd.bsky.social @harvardmed.bsky.social www.abc.net.au/listen/progr...
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- Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:
- Patients with idiopathic generalized epilepsy (IGE) typically present with generalized spike wave discharges with 'normal' brain MRI, leaving the neuroanatomical basis of IGE unclear.
- Reposted by Frederic SchaperInterested in an update on connectomic and adaptive deep brain stimulation for obsessive compulsive disorder? Take a look at our summary of this exciting field and how things could be brought together out now in BPS: www.biologicalpsychiatryjournal.com/article/S000... A brief 🧵
- Reposted by Frederic SchaperOut now in Brain A distinct pattern of brain damage intensifies political involvement, regardless of whether you're liberal, conservative, Democrat, or Republican. With coauthors S.Balters,S. Cohen-Zimerman,G.Zamboni,J.Grafman academic.oup.com/brain/advanc... @braincircuits.bsky.social
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- Reposted by Frederic SchaperEver wondered how well your Lead-DBS electrode localizations compare to expert solutions on the same data? Now, with Lead-Tutor, you can self-assess!
- Madan and Hart et al. introduce Lead-Tutor, an open-access educational resource that combines an imaging dataset of anonymized DBS cases with a software tool for self-teaching: doi.org/10.52294/001... @laurenahart.bsky.social @andreashorn.org @jordytasserie.bsky.social @ohbmofficial.bsky.social
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- Reposted by Frederic SchaperThe 12th Annual Deep Brain Stimulation Think Tank Proceedings are out and free to download. Check out Nico Dosenbach as he brings us up to speed on changes in the way we are thinking about the somato-cognitive action network (SCAN) functional connectivity to subcortex.
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- Reposted by Frederic SchaperSuper deserving of his award, @andreashorn.org identified specific tracts for specific diseases and even specific symptoms -> patient improvements in mx independent cohorts.
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- Reposted by Frederic SchaperI am hiring: PhD students, postdocs, admin personnel. Email me if you know somebody that may be interested in joining us in Cologne! 👇👇 Please RT for reach! 🙏🙏
- It’s a no brainer to join THE BEST brainer! 🧠@andreashorn.org is hiring, don’t wait to apply! Great opportunity to work with one of the best mentors and people in the field ☺️
- Reposted by Frederic SchaperI am excited to announce that I will be founding an institute for network stimulation at the University Hospital Cologne – already this coming May!
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- Reposted by Frederic Schaper🚨Interested in Dystonia?🚨 @braincircuits.bsky.social GPi DBS for dystonia is effective. More recently, STN DBS has been investigated, as an alternative. In what enfolded like a stunning thriller to me, Konstantin Butenko tells a tale of two networks… www.pnas.org/doi/10.1073/...
- Reposted by Frederic SchaperThe brain’s action-mode is created by a dedicated action-mode network (AMN) rdcu.be/d5odm. In the brain’s mode continuum, AMN sits opposite DMN’s default-mode, as yin-yang. AMN might be key in pain, apathy, Parkinson’s. New @natrevneurosci.bsky.social w/ Marc Raichle & @gordonneuro.bsky.social 🧵 ⬇️
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- Reposted by Frederic SchaperComing to #AES2024? Why spend the last conference day sleeping in when you could come to the Neuroimaging SIG? See you at 7am Dec 10 if you're curious about applications of brain gradients in TLE to understand cognitive and clinical phenotypes! 🌈 🌅
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- Reposted by Frederic SchaperVery happy to see this one out in the world 😁 a joint endeavour with Val Kebets 🌟 We used PLS to identify components linking symptoms of psychopathology with multimodal imaging markers in the ABCD dataset Get all the deets 👉 elifesciences.org/articles/87992
- 🍾 Now in press @elife.bsky.social Multimodal correlates of childhood psychopathology co-led by @jroyer.bsky.social , Valeria Kebets, @bttyeo.bsky.social & our many fantastic co-authors 🙏 based on the ABCD dataset 👉 elifesciences.org/articles/87992
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- Reposted by Frederic SchaperHad a lot of fun writing this news & views article on Converging Cortical Axes with @bogglerapture.bsky.social shorturl.at/LsB5p
- Tune in below at 12 EST today if you want to hear all about neuromodulation for epilepsy and Bob’s tips on job searching in academia👏🧠
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- Greatly looking forward to this @stimbrains.bsky.social session and sharing the stage with the legendary Robert S. Fisher! Want to hear about epilepsy network mapping and neuromodulation for epilepsy? Register below!👇 👇👇
- Reposted by Frederic SchaperWant to make beautiful scientific figures? Easy! The NIH released a library of 2000+ free scientific illustrations called *BioArt*. Check it out! bioart.niaid.nih.gov #AcademicSky #PsychSciSky 🧠🟦 🧪
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