Center for Brain Circuit Therapeutics
Center For Brain Circuit Therapeutics at Mass General Brigham / Harvard Medical School
- Reposted by Center for Brain Circuit TherapeuticsIn #DeepBrainStimulation the two major developments across the last decade have been 1. Adaptive DBS and 2. Connectomic DBS In a @natrevneurol.nature.com article with @julianneumann.bsky.social, we ask: Could the two be united into a common framework? www.nature.com/articles/s41... A 🧵
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- Reposted by Center for Brain Circuit TherapeuticsKonstantin Butenko compares four methods for mapping structural network activations in deep brain stimulation—two simple, two complex; some deterministic, some probabilistic—into @lead-dbs.org for direct use in the Fiber Filtering Explorer. See the methods paper below 👇👇
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- Reposted by Center for Brain Circuit TherapeuticsHonored to highlight our work @braincircuits.bsky.social @massgenbrigham.bsky.social Neuro Research Day. Thank you @shansiddiqi.bsky.social @fredschaper.bsky.social Sheena Baratano and Sam Snider for sharing your experience.
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- Reposted by Center for Brain Circuit TherapeuticsMassive, Herculanean work by @laurenahart.bsky.social and Garance Meyer to compile and integrate findings from DBS for epilepsy (20 targets!) including meta-analytical evidence for optimal stimulation sites for the two main targets (ANT & CM). Preprint out now 👇👇
- 🧠 ⚡️ Preprint alert ⚡️ 🧠 I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why. Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes www.researchgate.net/publication/...
- Reposted by Center for Brain Circuit Therapeutics🧠 ⚡️ Preprint alert ⚡️ 🧠 I️n the most comprehensive review of DBS in epilepsy, with 124 studies, 1,210 patients, and 20 anatomical targets we map where stimulation works best and why. Deep Brain Stimulation for Epilepsy: Optimal Targeting and Clinical Outcomes www.researchgate.net/publication/...
- Reposted by Center for Brain Circuit TherapeuticsCan a brain injury lead someone to commit a crime? Brain imaging is increasingly introduced as evidence in criminal trials but it remains unclear which structural injuries play a causal role in criminal behavior. @braincircuits.bsky.social @foxmdphd.bsky.social www.nature.com/articles/s41...
- Reposted by Center for Brain Circuit TherapeuticsThrilled our ADHD network mapping work is now out in Annals of the Child Neurology Society, and honored to be featured on the cover! 🔗 Full article: onlinelibrary.wiley.com/doi/full/10.... @childneurosoc.bsky.social @bostonchildrens.bsky.social @simonwarfield.bsky.social @braincircuits.bsky.social
- Reposted by Center for Brain Circuit TherapeuticsWe are actively looking for an administrative position to help lead the newly founded @netstim.org at the University of Cologne – please spread the word and/or let us know if you know somebody that could be interested! lnkd.in/eEbnXByJ
- 10,000! 🎂🍰 💯x💯!
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- Reposted by Center for Brain Circuit TherapeuticsHard to keep track about all the great things our labmembers have achieved recently:
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- Reposted by Center for Brain Circuit TherapeuticsCan brain injury cause the loss of visual imagination? We studied #aphantasia due to brain injury. Lesions were in many different regions but 100% were connected to the fusiform imagery node - a region active during visual mental imagery @braincircuits.bsky.social www.medrxiv.org/content/10.1...
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- Reposted by Center for Brain Circuit TherapeuticsTremor is a common symptom across many neurological disorders. But is there a shared tremor circuit across disorders - one that could guide treatment, regardless of diagnosis? We think: yes. Our study is out now in @natcomms.nature.com: 🔗 www.nature.com/articles/s41... 🧵 A thread.
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- Reposted by Center for Brain Circuit TherapeuticsMR guided focused ultrasound surgery is an effective and uprising treatment option for Essential tremor. But where is the optimal site to sonicate? Which spots to avoid due to side-effects? @science.org @braincircuits.bsky.social @netstim.org – a thread🧵! www.science.org/doi/10.1126/...
- Reposted by Center for Brain Circuit TherapeuticsWhen modeling volumes of tissue activated in subthalamic DBS for clinical outcomes, does it matter whether we process data in native or template space? Julianna Pijar and Clemens Neudorfer say No in the Brain Stimulation Journal: doi.org/10.1016/j.br...
- Reposted by Center for Brain Circuit TherapeuticsIt was a great honor to talk with the founding editor of Brain Stimulation, Dr. Harold Sackeim! Beyond the past, present and future of ECT, we covered the entire field of neuromodulation. Priceless insights from a key leader in the field! Tune in here 👇 stimulatingbrains.org/71-harold-sa...
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- Reposted by Center for Brain Circuit TherapeuticsWe had a truly inspiring and insightful conversation with Dr. Rees Cosgrove, Director of Epilepsy and Functional Neurosurgery at @brighamandwomens.bsky.social & Professor of Neurosurgery @harvardmed.bsky.social Rediscovering the lost art of brain lesions…! stimulatingbrains.org/70-rees-cosg...
- Reposted by Center for Brain Circuit TherapeuticsVery hard to say goodbye to these fantastic people. I will miss you guys! @braincircuits.bsky.social!
- Reposted by Center for Brain Circuit TherapeuticsProbably the most insightful and most important paper on physiomarkers of subthalamic DBS in a long while. Bravo @julianneumann.bsky.social @tsbinns.com and team!! Out at @natcomms.nature.com: www.nature.com/articles/s41...
- Reposted by Center for Brain Circuit TherapeuticsWas fun to do a podcast about our recent paper on creativity and brain disease with Dr Norman Swan @abcnewsbot.bsky.social @braincircuits.bsky.social @foxmdphd.bsky.social @harvardmed.bsky.social www.abc.net.au/listen/progr...
- Reposted by Center for Brain Circuit TherapeuticsIt's been pure joy to see Barbara grow over the years and I am very excited about her next steps as a post-doc at @braincircuits.bsky.social under supervision of none else than @foxmdphd.bsky.social – could not think of a better mentor for next steps in your career, Barbara!
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- Reposted by Center for Brain Circuit Therapeutics🚨 🥁 Preprint alert: The Deep Brain Stimulation Response Network in Parkinson’s Disease Operates in the High Beta Band ->> www.researchgate.net/publication/... <<--
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- Reposted by Center for Brain Circuit TherapeuticsLesions causing epilepsy map to a brain circuit, but what about generalized epilepsy? Great new paper (and thread) by @fredschaper.bsky.social identifies this circuit with implications for #DBS. @braincircuits.bsky.social
- Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:
- New @braincircuits.bsky.social Paper out 👇👇
- Out now in Brain A distinct pattern of brain damage intensifies political involvement, regardless of whether you're liberal, conservative, Democrat, or Republican. With coauthors S.Balters,S. Cohen-Zimerman,G.Zamboni,J.Grafman academic.oup.com/brain/advanc... @braincircuits.bsky.social
- Reposted by Center for Brain Circuit TherapeuticsCan brain damage change your political opinions? “No significant neuroanatomical circuit was associated with political ideology or party affiliation, but a distinct circuit was associated with intensity of political involvement” Work by @shansiddiqi.bsky.social @braincircuits.bsky.social
- Out now in Brain A distinct pattern of brain damage intensifies political involvement, regardless of whether you're liberal, conservative, Democrat, or Republican. With coauthors S.Balters,S. Cohen-Zimerman,G.Zamboni,J.Grafman academic.oup.com/brain/advanc... @braincircuits.bsky.social
- Reposted by Center for Brain Circuit TherapeuticsHuge thank you to first author Gongjun Ji for leading this study, to @foxmdphd.bsky.social for his invaluable mentorship at @braincircuits.bsky.social, and all collaborators for their support and generous sharing of their data:
- New @braincircuits.bsky.social paper out at @naturecomms.bsky.social 👇👇
- Is generalized epilepsy a seizure of the whole brain or a specific brain network? In our new paper out now in @naturecomms.bsky.social, we investigate this by combining brain abnormalities and DBS with the human connectome. Paper: nature.com/articles/s41... A 🧵 below:
- Reposted by Center for Brain Circuit TherapeuticsInterested in an update on connectomic and adaptive deep brain stimulation for obsessive compulsive disorder? Take a look at our summary of this exciting field and how things could be brought together out now in BPS: www.biologicalpsychiatryjournal.com/article/S000... A brief 🧵
- Reposted by Center for Brain Circuit TherapeuticsAdaptive DBS was recently approved by the FDA – in this episode, we talk with @toddherrington.bsky.social about the underlying ADAPT-PD trial, the mechanism of action of DBS, and the potential role of stem cell therapy in movement disorders. Tune in here 👇🎧👇🎧 stimulatingbrains.org/68-todd-herr...