Arnaud Krebs
Group leader at EMBL Heideberg
embl.org/groups/krebs/
- Reposted by Arnaud Krebs🚨WE'RE RECRUITING AT @irbbarcelona.org !!!! --- ADVANCED GENOMICS FACILITY MANAGER --- An amazing opportunity to help us drive the fight against cancer and other aging-related diseases using Single-cell, Bulk and Spatial genomics!!!! APPLY NOW!!!! recruitment.irbbarcelona.org/jobs/7124180...
- Come and join us at EMBL. Best way to get your scientific career started!
- Recruitment for the EMBL International PhD Programme is officially open! 🔊 At EMBL, we train young scientists to become skilled and creative future leaders in academia, industry and other sectors. Start your career in the life sciences with us! 🔎 Read more here: tinyurl.com/4jdt2ra5
- Reposted by Arnaud Krebs
- Nature research paper: Construction of complex and diverse DNA sequences using DNA three-way junctions go.nature.com/4qu2ExZ
- Very important work to reconcile canonical transcription initiation structures with the promoter diversity occurring in vivo. Some explanation on how the large majority of our promoters (TATA-less) ma initiate transcription through contacts downstream of the TSS.
- The @zeitlingerlab.bsky.social is pleased to announce @sergio-gma91.bsky.social’s preprint “High-resolution binding data of TFIID and cofactors show promoter-specific differences in vivo” (www.biorxiv.org/content/10.6...). TLDR; TFIID behaves differently depending on promoter type. More below:
- Epigenetics that matters! Very cool work on hard to hard-to-access cell types . Finally some solid epigenetics examples that should be used in textbooks! Congrats to Mathieu and team @embl.org Rome!
- This went under the radar but answers a fundamental question in Epigenetics... From many hundreds of olfactory receptor genes, each neuron selects expression of only single one (near-randomly). How? Outstanding work from Mathieu Boulard and colleagues www.biorxiv.org/content/10.6...
- This is nuts. Dead ringers fused. Cronenberg would have loved that.
- A fascinating case report. The DNA of a female murder victim was genotyped and it turns out that she has been a chimera: a mixture of 46XX/46XY cell lines. The analysis (STR-based) found: 1. The maternal chromosome was identical between the two cell lines. www.fsigenetics.com/article/S187... 1/6
- Reposted by Arnaud KrebsJoin @stirlingchurchman.bsky.social, @moffittlab.bsky.social, @saramostafavi.bsky.social, me and all speakers for the 2026 CSHL meeting Systems Biology: Global Regulation of Gene Expression, March 11-14. Abstract deadline January 9! More infos and registration at meetings.cshl.edu/meetings.asp...
- Reposted by Arnaud KrebsStill time to apply until January, 19th!
- We are recruiting a tenure track professor in the broader area of molecular biology @zmbh.uni-heidelberg.de at Heidelberg University! www.nature.com/naturecareer... Please share and apply!
- The best chromatin kickstart pack you will find this year - please consider it if you want to get in the field or consolidate your skills. Hands on training and top notch speakers!
- 👉 Chromatin Summer School 2026 – Apply Now! Join us in Munich 17–29 August 2026 for an immersive program on chromatin biology: 🔬 Expert lectures 🧪 Hands-on training 🤝 Global networking Open to 14 PhD students worldwide (sponsorship available) 👉 Apply here: bit.ly/4oGDR8f #ChromatinBiology
- Reposted by Arnaud KrebsAfter a huge amount of work w/ @alex-stark.bsky.social's group, a new version of our Ledidi preprint is now out! In an era of AI-designed proteins, the next leap will be controlling when, where, and how much of these proteins are expressed in living cells. www.biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsAn early Christmas present for those interested in chromatin and transcription! Fantastic work from @au-ho-yu.bsky.social and @aleksszczurek.bsky.social . Thanks to Inge and Michiel for their help. Please repost! www.biorxiv.org/content/10.6...
- Reposted by Arnaud KrebsAre you ready for the 17th edition of 'Transcription and chromatin'? Our conference remains a must-attend event for anyone engaged in the forefront of transcription research and we hope you can join us! 🧬 25 – 28 August 2026 Submit your abstract by 25 May: s.embl.org/trm26-01-bl #EMBLTranscript
- Reposted by Arnaud Krebs👉 Chromatin Summer School 2026 – Apply Now! Join us in Munich 17–29 August 2026 for an immersive program on chromatin biology: 🔬 Expert lectures 🧪 Hands-on training 🤝 Global networking Open to 14 PhD students worldwide (sponsorship available) 👉 Apply here: bit.ly/4oGDR8f #ChromatinBiology
- Reposted by Arnaud KrebsIts out!!!
A little reading before the Christmas break by the one and only @nucleosomepolice.bsky.social in @annualreviews.bsky.social The expanding Histone universe: Histone-Based DNA organization in noneukaryotic organisms www.annualreviews.org/content/jour...
- Reposted by Arnaud KrebsPlease RT 📧 Registration open for ➡️"Summer School on Chromatin Biology" Our 2 weeks hands on expedition 🧪👩💻August 2026. 3. edition. Learn CUT@Tag, CUT@Run, ChIPseq, ATACseq AND to analyse your own data at @helmholtzmunich.bsky.social Daily letures by experts in the field ! ▶️ shorturl.at/jrA8i
- Reposted by Arnaud KrebsIt's always exciting when the latest edition of JASPAR comes out. Great leadership by @amathelier.bsky.social and pleased to welcome @anshulkundaje.bsky.social to the journey. #Jaspar2026 academic.oup.com/nar/advance-...
- Reposted by Arnaud KrebsWe are pleased to announce a new preprint by @mlweilert.bsky.social: “Widespread low-affinity motifs enhance chromatin accessibility and regulatory potential in mESCs” (www.biorxiv.org/content/10.1...). See summary and longer recap below: (TLDR; low-affinity motifs matter as pioneers!)
- Reposted by Arnaud KrebsDeadline is coming up soon!! www.mdc-berlin.de/career/jobs/...
- Reposted by Arnaud KrebsThe 21st Course on Epigenetics which will take place from March 25th to April 1st, 2026 at the Institut Curie (Paris). The Course is open to M2 and PhD students. Application via the Advanced Training Office website before December 15th, 2025 at: minilien.curie.fr/3avv47
- And the science is amazing! Apply!
- We are looking for a postdoc to join our team! If you're interested in translating a cutting edge genomics technology (www.nature.com/articles/s41...) to real-life applications in hematology, this is for you. We offer a unique working environment ON THE BEACH: recruitment.crg.eu/content/jobs...
- Reposted by Arnaud KrebsThis Thursday, we’re pleased to welcome Philipp Korber. Prof Korber leads a research group on “Nucleosome Positioning & Remodeling in Yeasts” at the @bmc-lmu.bsky.social in Munich. His work has identified ATP-dependent chromatin remodelers as major determinants of nucleosome positioning. Join us!
- Reposted by Arnaud KrebsAn Asgard archaeon with internal membrane compartments Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors! www.biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsVous êtes étudiant(e) en informatique, ingénierie ou mathématiques dans une université ou une grande école ? La biologie et le fonctionnement du vivant vous intéressent ? Envie d'élargir vos horizons ? Ce stage pourrait vous convenir. www.ebi.ac.uk/about/jobs/i...
- Reposted by Arnaud KrebsDing ding! New Restrictor paper out showing that ZC3H4 affects transcription universally at a checkpoint downstream and distinct to Integrator! Sequential verification of transcription by Integrator and Restrictor: Molecular Cell www.cell.com/molecular-ce...
- Reposted by Arnaud KrebsEver wondered what drives enhancer-promoter specificity? Why would an enhancer activate one gene rather than another neighboring one? Check our latest preprint, led by @mmasoura.bsky.social, to find out! www.biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsOut now! 🎉 Check the thread & preprint to see why we think E–P specificity is real in mammals — and, well, a few other interesting things popped up too 👀 Huge thanks to @danielibrahim.bsky.social, @arnaudkr.bsky.social & @stemundi.bsky.social and fantastic people in their labs — what a journey! 🧪🔬
- What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...
- A genetic engineering tour de force by @blanka-majchrzycka.bsky.social. Systematic dissection of promoter function in relevant genomic context! Spoiler, promoter matters! Happy we could help on this!
- What is a promoter? And how does it work? We very happy to share our latest work trying to understand enhancer-promoter compatibility. I am very excited about the results of @blanka-majchrzycka.bsky.social, which changed the way I think about promoters www.biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsModel organisms as platforms for training scientific minds www.nature.com/articles/s41...
- PREACH! www.nature.com/articles/s41...
- Reposted by Arnaud KrebsThe @crick.ac.uk is recruiting Early Career Group Leaders - Lab set-up, research costs, salaries for up to 5 researchers - Support for up to 12 years - Access to our core facilities - Competitive salary - Fantastic colleagues - All areas of biology Deadline 27 Nov www.crick.ac.uk/careers-stud...
- Unique opportunity to get hands on experience at post-doc+ level in cutting edge environment!
- I am hiring! - looking for a Staff Scientist to co-run my research group with me. Staff Scientist is a senior professional scientist role at EMBL. Please forward to people you might know who could be interested! embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
- Reposted by Arnaud Krebs📢We're #hiring Group Leaders! Apply to lead a lab at Janelia & advance biology using theory, computational modeling & machine learning. 🔹5-year renewable appointment 🔹Pioneer new tools & approaches 🔹Collaborate across disciplines Apply by Nov. 4👉 janelia.link/groupleader
- Reposted by Arnaud KrebsTwo more days to apply for the VBC PhD program! Join us in beautiful Vienna to explore exciting scientific questions under fantastic mentorship and in an outstanding training environment!
- Our PhD program offers many training activities and courses for your future career. Check out the range of fully-funded PhD positions in our Autumn call before 10 October 2025: www.vbcphd.at
- Reposted by Arnaud Krebs🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China
- Reposted by Arnaud KrebsCongratulations! nice to see this out!
- 🧵1/ Excited to share our new paper introducing a new #singlecell assay: scTF-seq, a high-throughput single-cell approach to explore how transcription factor (TF) dose shapes cell identity and reprogramming outcomes. 🔗 www.nature.com/articles/s41... Big congrats to the entire team @EPFL & @SIAT_China
- Reposted by Arnaud KrebsWe're growing the VIB.AI Machine Learning Unit, and we're hiring! 📌 Head of the Machine Learning Unit 📌 LLM Engineer Both roles are based in Leuven, Belgium, at the heart of a thriving research ecosystem. vib.ai/en/opportunities#/j… Apply by October 31st.
- Reposted by Arnaud Krebs#Jobalert 🚨: Please RT ! Looking for a #PhD student for exciting project on the interphase between epigenetics and cellular metabolism: How do (nuclear) metabolic enzymes reguate chromatin function ? #epigenomics, #epigenetics, #metabolism www.helmholtz-munich.de/en/ife/job-o...
- Reposted by Arnaud Krebs✨Exciting news: the main story of my PhD is out in Science! Together with Christine Moene @cmoene.bsky.social, we explored what happens when you scramble the genome—revealing how Sox2’s position shapes enhancer activation. 📖 Read the full story here: www.science.org/doi/10.1126/...
- Reposted by Arnaud KrebsHave you ever wondered how the exact location of a gene affects it's activity? The main story of my PhD deals with exactly that question, and is now published in Science! ✨ www.science.org/doi/10.1126/... My amazing co-author and friend @mathiaseder.bsky.social summarized the highlights for you
- Reposted by Arnaud KrebsJoin EMBL AI! We have ambitious plans to transform life sciences research through AI. Interested in using ML/AI to solve complex interdisciplinary challenges? We’re looking for two senior leaders based at EMBL Heidelberg👇
- Reposted by Arnaud KrebsWe're getting started in ~90 minutes! In addition to watching the seminars, remember you can join us on Discord to chat about transcription and chromatin whenever you want! discord.com/invite/dXqT89r
- Let’s kickstart new series of #FragileNucleosome seminars! We are delighted to have @gracebower.bsky.social from Kvon lab and @creminslab.bsky.social to present their work! Register here for upcoming session and the entire series: us06web.zoom.us/webinar/regi...
- Reposted by Arnaud KrebsDo not forget to apply to the FEBS Advanced Lecture Course: 6th Danube Conference on Epigenetics (19–22 October 2026, Budapest, Hungary. Will be a great meeting as always. Check out the site: network.febs.org/posts/febs-a...
- Reposted by Arnaud KrebsCheck it out, Chromatin Kids! Chromatin remodeller does stuff to Transcription Factors! Functions where it is seldom seen! Both decreases and increases chromatin accessibility! How cool is that?
- The chromatin remodeller CHD4 controls both nucleosome integrity and transcription factor binding to promote activity of active regulatory elements and to prevent activation of silent enhancers biorxiv.org/content/10.1101/202…
- Reposted by Arnaud KrebsExcited to share another new preprint from our lab in which we developed a cluster-based phasing strategy using long read nano-NOMe-seq data to link distinct CTCF binding states—captured at the single molecule level—to the transcriptional status of genes: biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsBecome our colleague at @fmiscience.bsky.social! The FMI is a very special place to start your lab: a vibrant international institute with world-class research groups and facilities, core funding, fantastic trainees, great colleagues😅, and a collegial culture. Get in touch if you're interested!
- 🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬 Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at www.fmi.ch/education-ca...
- Reposted by Arnaud Krebs📢Last chance today! We are looking forward to receiving your applications👇!
- 📣 We’re recruiting 1-2 Group Leaders! NCMBM is looking for early-career researchers ready to establish their independent research groups! 🧬 With an attractive start-up package, help us shape the future of molecular biosciences and medicine in 🇳🇴 and be part of the @nordicembl.bsky.social!
- Reposted by Arnaud KrebsJust brilliat work by Kasit and colleagues in @arnaudkr.bsky.social's group @embl.org. This is leveraging the "everyday" length of ONT (20KB) plus exogenous modification to sort out co-occupancy between enhancers and promoters (and inter-enhancer).
- Activity of most genes is controlled by multiple enhancers, but is there activation coordinated? We leveraged Nanopore to identify a specific set of elements that are simultaneously accessible on the same DNA molecules and are coordinated in their activation. www.biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsHuge thanks to the co-first author @kasitc.bsky.social Also thanks to Rene, Marc Jan, Karine, Kim, and especially @arnaudkr.bsky.social @embl.org @dfg.de. Finally, Kasit will be presenting the story at the @cshlnews.bsky.social #cshlmoet next week! Please stop by if you are around!
- This is not a HiC map! Ever wondered if multiple enhancers get activated simultaneously? We measured chromatin accessibility on thousands of molecules by nanopore to create genome-wide co-accessibility maps. Proud of @mathias-boulanger.bsky.social @kasitc.bsky.social Biology in the thread👇
- Activity of most genes is controlled by multiple enhancers, but is there activation coordinated? We leveraged Nanopore to identify a specific set of elements that are simultaneously accessible on the same DNA molecules and are coordinated in their activation. www.biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsOur featured article: Epigenome dynamics in early mammalian embryogenesis by Adam Burton & Maria-Elena Torres-Padilla go.nature.com/45UA8Ob
- Reposted by Arnaud Krebs🎉 Congrats to the poster prize winners at #EMBLSingleMolecule! 🏅 Adam Cawte, University of Oxford, UK 🏅 Masa Shimazoe, National Institute of Genetics, Japan 🧬 Explore their winning abstracts & posters in our latest blog post: 🔗 s.embl.org/grg25-01-posters
- Reposted by Arnaud KrebsRegistration is still open for Transcription and Chromatin UK 2025. Join our growing research community in Manchester this September!
- Reposted by Arnaud KrebsFunny how many institutions that self-refer as “leading” have a wait-and-see approach to decision making…
- Bluesky is favoured by many academics - so why are universities taking a "wait-and-see" approach to it, despite migrating from X? Latest analysis from @andytattersall.bsky.social, plus views on why many universities remain silent on Bluesky. www.researchprofessionalnews.com/rr-news-uk-u...
- Reposted by Arnaud KrebsWe are hiring! A 3-year postdoc in #Chromatin #Cancer #Epigenetics at University of Oslo, Norway and co-supervised by @amathelier.bsky.social You will be part of @cancelluio.bosky.social. We focus on #Sarcoma #Epigenome #CRISPR and Drug screen studies. Find out more and apply here: shorturl.at/DtLHM
- Reposted by Arnaud KrebsExcited to share the latest work from the lab led by @eharo84.bsky.social, in which we have used synthetic biology to explore the mechanisms by which different types of long-range enhancers ensure robust and precise developmental gene expression www.biorxiv.org/content/10.1...
- Reposted by Arnaud KrebsEMBL is back on hiring faculty! Check out the multiple open positions: 3 PIs- 2 in Heidelberg incl. our Molecular Systems Biology Unit, 1 in Grenoble 1 Head of Unit (Cell Biology & Biophysics, Heidelberg). Closing deadlines in Sep! +3 more positions to come out then, stay tuned... @embl.org
- Reposted by Arnaud KrebsOpen Team Leader position @embl.org to head & reshape our Genomics Core facility. Interested in providing & developing state-of-the art omics tech to a wide community? A very vibrant, dynamic place to work with fantastic colleagues. Closing Sept 30th embl.wd103.myworkdayjobs.com/en-US/EMBL/j...
- Reposted by Arnaud KrebsExcited to see this published with additional data following our preprint a while back. Cool combination (in our biased view) of controlled TF expression and machine learning to decode chromatin sensitivity. www.sciencedirect.com/science/arti....
- Reposted by Arnaud Krebs📢One month left to apply to our Group Leader position! 🌟A chance to be part of @nordicembl.bsky.social: “The Partnership connects us with an exceptional network of researchers, facilities, and complementary expertise. It opens doors to meaningful scientific exchange”, says @amathelier.bsky.social.
- Reposted by Arnaud KrebsWe’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠 Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels. Take a look at these four open positions 👇
